PubMed:32522282 / 1302-2613
Annnotations
LitCovid-OGER-BB
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T21 | 27-35 | GO:0007565 | denotes | pregnant |
T22 | 51-60 | GO:0007565 | denotes | pregnancy |
T23 | 156-164 | GO:0042696 | denotes | menarche |
T24 | 194-206 | GO:0042703 | denotes | menstruation |
T25 | 319-323 | CHEBI:17544 | denotes | FiO2 |
T26 | 319-323 | CHEBI:17544 | denotes | FiO2 |
T27 | 368-380 | CHEBI:28619 | denotes | azithromycin |
T28 | 368-380 | CHEBI:28619 | denotes | azithromycin |
T29 | 368-380 | DG_6 | denotes | azithromycin |
T30 | 384-402 | CHEBI:5801 | denotes | hydroxychloroquine |
T31 | 384-402 | CHEBI:5801 | denotes | hydroxychloroquine |
T32 | 384-402 | DG_20 | denotes | hydroxychloroquine |
T33 | 426-433 | CHEBI:15854 | denotes | quinine |
T34 | 426-433 | CHEBI:15854 | denotes | quinine |
T35 | 437-438 | CHEBI:51231 | denotes | 4 |
T36 | 437-438 | CHEBI:51231 | denotes | 4 |
T37 | 438-439 | CHEBI:86228 | denotes | - |
T38 | 438-439 | CHEBI:86228 | denotes | - |
T39 | 439-453 | CHEBI:36709 | denotes | aminoquinoline |
T40 | 439-453 | CHEBI:36709 | denotes | aminoquinoline |
T41 | 479-486 | GO:0007605 | denotes | hearing |
T42 | 534-540 | GO:0007601 | denotes | Visual |
T43 | 580-585 | UBERON:0002107 | denotes | liver |
T44 | 651-667 | UBERON:0001555 | denotes | gastrointestinal |
T45 | 669-681 | UBERON:0001016 | denotes | neurological |
T46 | 785-792 | UBERON:0000948 | denotes | cardiac |
T47 | 915-922 | CHEBI:4551 | denotes | digoxin |
T48 | 915-922 | CHEBI:4551 | denotes | digoxin |
T49 | 926-933 | CHEBI:17234 | denotes | Glucose |
T50 | 926-933 | CHEBI:17234 | denotes | Glucose |
T51 | 933-936 | CHEBI:14314 | denotes | -6- |
T52 | 933-936 | CHEBI:14314 | denotes | -6- |
T53 | 936-945 | CHEBI:18367 | denotes | phosphate |
T54 | 936-945 | CHEBI:18367 | denotes | phosphate |
T55 | 1000-1005 | UBERON:0000178 | denotes | Blood |
T56 | 1006-1013 | CHEBI:17234 | denotes | glucose |
T57 | 1006-1013 | CHEBI:17234 | denotes | glucose |
T58 | 1212-1217 | CHEBI:16933 | denotes | ergot |
T59 | 1212-1217 | CHEBI:16933 | denotes | ergot |
T60 | 1218-1227 | CHEBI:23943 | denotes | alkaloids |
T61 | 1218-1227 | CHEBI:23943 | denotes | alkaloids |
T62 | 1266-1273 | CHEBI:4551 | denotes | digoxin |
T63 | 1266-1273 | CHEBI:4551 | denotes | digoxin |
LitCovid-PD-FMA-UBERON
Id | Subject | Object | Predicate | Lexical cue | fma_id |
---|---|---|---|---|---|
T2 | 580-585 | Body_part | denotes | liver | http://purl.org/sig/ont/fma/fma7197 |
T3 | 926-933 | Body_part | denotes | Glucose | http://purl.org/sig/ont/fma/fma82743 |
T4 | 1000-1005 | Body_part | denotes | Blood | http://purl.org/sig/ont/fma/fma9670 |
T5 | 1006-1013 | Body_part | denotes | glucose | http://purl.org/sig/ont/fma/fma82743 |
T6 | 1073-1079 | Body_part | denotes | mental | http://purl.org/sig/ont/fma/fma264279 |
LitCovid-PD-UBERON
Id | Subject | Object | Predicate | Lexical cue | uberon_id |
---|---|---|---|---|---|
T2 | 580-585 | Body_part | denotes | liver | http://purl.obolibrary.org/obo/UBERON_0002107 |
T3 | 1000-1005 | Body_part | denotes | Blood | http://purl.obolibrary.org/obo/UBERON_0000178 |
LitCovid-PD-MONDO
Id | Subject | Object | Predicate | Lexical cue | mondo_id |
---|---|---|---|---|---|
T6 | 357-364 | Disease | denotes | allergy | http://purl.obolibrary.org/obo/MONDO_0005271 |
T7 | 406-422 | Disease | denotes | hypersensitivity | http://purl.obolibrary.org/obo/MONDO_0000605|http://purl.obolibrary.org/obo/MONDO_0005271 |
T9 | 479-491 | Disease | denotes | hearing loss | http://purl.obolibrary.org/obo/MONDO_0005365 |
T10 | 494-503 | Disease | denotes | Psoriasis | http://purl.obolibrary.org/obo/MONDO_0005083 |
T11 | 506-517 | Disease | denotes | Retinopathy | http://purl.obolibrary.org/obo/MONDO_0005283 |
T12 | 580-594 | Disease | denotes | liver diseases | http://purl.obolibrary.org/obo/MONDO_0005154 |
T13 | 606-616 | Disease | denotes | amoebiasis | http://purl.obolibrary.org/obo/MONDO_0005644 |
T14 | 686-709 | Disease | denotes | hematological disorders | http://purl.obolibrary.org/obo/MONDO_0005570 |
T15 | 793-813 | Disease | denotes | conduction disorders | http://purl.obolibrary.org/obo/MONDO_0007264 |
T16 | 814-825 | Disease | denotes | arrhythmias | http://purl.obolibrary.org/obo/MONDO_0007263 |
T17 | 880-897 | Disease | denotes | Myasthenia gravis | http://purl.obolibrary.org/obo/MONDO_0009688 |
T18 | 926-970 | Disease | denotes | Glucose-6-phosphate dehydrogenase deficiency | http://purl.obolibrary.org/obo/MONDO_0005775 |
T19 | 973-982 | Disease | denotes | Porphyria | http://purl.obolibrary.org/obo/MONDO_0019142|http://purl.obolibrary.org/obo/MONDO_0037939 |
T21 | 985-998 | Disease | denotes | Hypoglycaemia | http://purl.obolibrary.org/obo/MONDO_0004946 |
T22 | 1073-1087 | Disease | denotes | mental illness | http://purl.obolibrary.org/obo/MONDO_0002025 |
LitCovid-PD-CLO
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T12 | 61-65 | http://purl.obolibrary.org/obo/UBERON_0000473 | denotes | test |
T13 | 541-546 | http://purl.obolibrary.org/obo/UBERON_0007688 | denotes | field |
T14 | 580-585 | http://purl.obolibrary.org/obo/UBERON_0002107 | denotes | liver |
T15 | 580-585 | http://www.ebi.ac.uk/efo/EFO_0000887 | denotes | liver |
T16 | 742-744 | http://purl.obolibrary.org/obo/CLO_0053799 | denotes | 45 |
T17 | 873-875 | http://purl.obolibrary.org/obo/CLO_0007874 | denotes | ms |
T18 | 1000-1005 | http://purl.obolibrary.org/obo/UBERON_0000178 | denotes | Blood |
T19 | 1000-1005 | http://www.ebi.ac.uk/efo/EFO_0000296 | denotes | Blood |
LitCovid-PD-CHEBI
Id | Subject | Object | Predicate | Lexical cue | chebi_id |
---|---|---|---|---|---|
T8 | 368-380 | Chemical | denotes | azithromycin | http://purl.obolibrary.org/obo/CHEBI_2955 |
T9 | 384-402 | Chemical | denotes | hydroxychloroquine | http://purl.obolibrary.org/obo/CHEBI_5801 |
T10 | 426-433 | Chemical | denotes | quinine | http://purl.obolibrary.org/obo/CHEBI_137041|http://purl.obolibrary.org/obo/CHEBI_15854 |
T12 | 439-453 | Chemical | denotes | aminoquinoline | http://purl.obolibrary.org/obo/CHEBI_36709 |
T13 | 915-922 | Chemical | denotes | digoxin | http://purl.obolibrary.org/obo/CHEBI_145795|http://purl.obolibrary.org/obo/CHEBI_4551 |
T15 | 926-933 | Chemical | denotes | Glucose | http://purl.obolibrary.org/obo/CHEBI_17234|http://purl.obolibrary.org/obo/CHEBI_4167|http://purl.obolibrary.org/obo/CHEBI_42758 |
T18 | 936-945 | Chemical | denotes | phosphate | http://purl.obolibrary.org/obo/CHEBI_18367|http://purl.obolibrary.org/obo/CHEBI_26020|http://purl.obolibrary.org/obo/CHEBI_35780|http://purl.obolibrary.org/obo/CHEBI_43474 |
T22 | 1006-1013 | Chemical | denotes | glucose | http://purl.obolibrary.org/obo/CHEBI_17234|http://purl.obolibrary.org/obo/CHEBI_4167 |
T24 | 1212-1227 | Chemical | denotes | ergot alkaloids | http://purl.obolibrary.org/obo/CHEBI_23943 |
T25 | 1218-1227 | Chemical | denotes | alkaloids | http://purl.obolibrary.org/obo/CHEBI_22315 |
T26 | 1266-1273 | Chemical | denotes | digoxin | http://purl.obolibrary.org/obo/CHEBI_145795|http://purl.obolibrary.org/obo/CHEBI_4551 |
LitCovid-PD-HP
Id | Subject | Object | Predicate | Lexical cue | hp_id |
---|---|---|---|---|---|
T1 | 357-364 | Phenotype | denotes | allergy | http://purl.obolibrary.org/obo/HP_0012393 |
T2 | 406-422 | Phenotype | denotes | hypersensitivity | http://purl.obolibrary.org/obo/HP_0041092 |
T3 | 479-491 | Phenotype | denotes | hearing loss | http://purl.obolibrary.org/obo/HP_0000365 |
T4 | 494-503 | Phenotype | denotes | Psoriasis | http://purl.obolibrary.org/obo/HP_0003765 |
T5 | 506-517 | Phenotype | denotes | Retinopathy | http://purl.obolibrary.org/obo/HP_0000488 |
T6 | 580-594 | Phenotype | denotes | liver diseases | http://purl.obolibrary.org/obo/HP_0001392 |
T7 | 814-825 | Phenotype | denotes | arrhythmias | http://purl.obolibrary.org/obo/HP_0011675 |
T8 | 829-851 | Phenotype | denotes | prolonged QTc interval | http://purl.obolibrary.org/obo/HP_0005184 |
T9 | 880-890 | Phenotype | denotes | Myasthenia | http://purl.obolibrary.org/obo/HP_0003473 |
T10 | 985-998 | Phenotype | denotes | Hypoglycaemia | http://purl.obolibrary.org/obo/HP_0001943 |
LitCovid-PD-GO-BP
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T2 | 156-164 | http://purl.obolibrary.org/obo/GO_0042696 | denotes | menarche |
T3 | 194-206 | http://purl.obolibrary.org/obo/GO_0042703 | denotes | menstruation |
T4 | 406-422 | http://purl.obolibrary.org/obo/GO_0002524 | denotes | hypersensitivity |
T5 | 479-486 | http://purl.obolibrary.org/obo/GO_0007605 | denotes | hearing |
T6 | 736-740 | http://purl.obolibrary.org/obo/GO_0005006 | denotes | eGFR |
T7 | 785-803 | http://purl.obolibrary.org/obo/GO_0061337 | denotes | cardiac conduction |
LitCovid-sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T11 | 0-1311 | Sentence | denotes | Fertile women* must not be pregnant, i.e. negative pregnancy test must be available at inclusion • Informed consent signed by the patient *Defined as after menarche and until postmenopausal (no menstruation for 12 months) Exclusion criteria: • At the time of recruitment, the patient uses >5 LO2/min (equivalent to 40% FiO2 if measured) • Known intolerance/allergy to azithromycin or hydroxychloroquine or hypersensitivity to quinine or 4-aminoquinoline derivatives • Neurogenic hearing loss • Psoriasis • Retinopathy • Maculopathy • Visual field changes • Breastfeeding • Severe liver diseases other than amoebiasis (INR> 1.5 spontaneously) • Severe gastrointestinal, neurological and hematological disorders (investigator-assessed) • eGFR <45 ml/min/1.73 m2 • Clinically significant cardiac conduction disorders/arrhythmias or prolonged QTc interval (QTc (f) of> 480/470 ms). • Myasthenia gravis • Treatment with digoxin* • Glucose-6-phosphate dehydrogenase deficiency • Porphyria • Hypoglycaemia (Blood glucose at any time since hospitalization of <3.0 mmol/L) • Severe mental illness which significantly impedes cooperation • Severe linguistic problems that significantly hinder cooperation • Treatment with ergot alkaloids *The patient must not be treated with digoxin for the duration of the intervention. |
hydroxychloroquine
Id | Subject | Object | Predicate | Lexical cue | hp_id |
---|---|---|---|---|---|
T1 | 357-364 | Phenotype | denotes | allergy | http://purl.obolibrary.org/obo/HP_0012393 |
T2 | 406-422 | Phenotype | denotes | hypersensitivity | http://purl.obolibrary.org/obo/HP_0041092 |
T3 | 479-491 | Phenotype | denotes | hearing loss | http://purl.obolibrary.org/obo/HP_0000365 |
T4 | 494-503 | Phenotype | denotes | Psoriasis | http://purl.obolibrary.org/obo/HP_0003765 |
T5 | 506-517 | Phenotype | denotes | Retinopathy | http://purl.obolibrary.org/obo/HP_0000488 |
T6 | 580-594 | Phenotype | denotes | liver diseases | http://purl.obolibrary.org/obo/HP_0001392 |
T7 | 814-825 | Phenotype | denotes | arrhythmias | http://purl.obolibrary.org/obo/HP_0011675 |
T8 | 829-851 | Phenotype | denotes | prolonged QTc interval | http://purl.obolibrary.org/obo/HP_0005184 |
T9 | 880-890 | Phenotype | denotes | Myasthenia | http://purl.obolibrary.org/obo/HP_0003473 |
T10 | 985-998 | Phenotype | denotes | Hypoglycaemia | http://purl.obolibrary.org/obo/HP_0001943 |
Inflammaging
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T11 | 0-1311 | Sentence | denotes | Fertile women* must not be pregnant, i.e. negative pregnancy test must be available at inclusion • Informed consent signed by the patient *Defined as after menarche and until postmenopausal (no menstruation for 12 months) Exclusion criteria: • At the time of recruitment, the patient uses >5 LO2/min (equivalent to 40% FiO2 if measured) • Known intolerance/allergy to azithromycin or hydroxychloroquine or hypersensitivity to quinine or 4-aminoquinoline derivatives • Neurogenic hearing loss • Psoriasis • Retinopathy • Maculopathy • Visual field changes • Breastfeeding • Severe liver diseases other than amoebiasis (INR> 1.5 spontaneously) • Severe gastrointestinal, neurological and hematological disorders (investigator-assessed) • eGFR <45 ml/min/1.73 m2 • Clinically significant cardiac conduction disorders/arrhythmias or prolonged QTc interval (QTc (f) of> 480/470 ms). • Myasthenia gravis • Treatment with digoxin* • Glucose-6-phosphate dehydrogenase deficiency • Porphyria • Hypoglycaemia (Blood glucose at any time since hospitalization of <3.0 mmol/L) • Severe mental illness which significantly impedes cooperation • Severe linguistic problems that significantly hinder cooperation • Treatment with ergot alkaloids *The patient must not be treated with digoxin for the duration of the intervention. |
T11 | 0-1311 | Sentence | denotes | Fertile women* must not be pregnant, i.e. negative pregnancy test must be available at inclusion • Informed consent signed by the patient *Defined as after menarche and until postmenopausal (no menstruation for 12 months) Exclusion criteria: • At the time of recruitment, the patient uses >5 LO2/min (equivalent to 40% FiO2 if measured) • Known intolerance/allergy to azithromycin or hydroxychloroquine or hypersensitivity to quinine or 4-aminoquinoline derivatives • Neurogenic hearing loss • Psoriasis • Retinopathy • Maculopathy • Visual field changes • Breastfeeding • Severe liver diseases other than amoebiasis (INR> 1.5 spontaneously) • Severe gastrointestinal, neurological and hematological disorders (investigator-assessed) • eGFR <45 ml/min/1.73 m2 • Clinically significant cardiac conduction disorders/arrhythmias or prolonged QTc interval (QTc (f) of> 480/470 ms). • Myasthenia gravis • Treatment with digoxin* • Glucose-6-phosphate dehydrogenase deficiency • Porphyria • Hypoglycaemia (Blood glucose at any time since hospitalization of <3.0 mmol/L) • Severe mental illness which significantly impedes cooperation • Severe linguistic problems that significantly hinder cooperation • Treatment with ergot alkaloids *The patient must not be treated with digoxin for the duration of the intervention. |