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PubMed:32510927 JSONTXT

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Anatomy-MAT

Id Subject Object Predicate Lexical cue mat_id
T1 1121-1124 Body_part denotes gut http://purl.obolibrary.org/obo/MAT_0000043

mondo_disease

Id Subject Object Predicate Lexical cue mondo_id
T1 243-249 Disease denotes cancer http://purl.obolibrary.org/obo/MONDO_0004992
T2 385-391 Disease denotes cancer http://purl.obolibrary.org/obo/MONDO_0004992
T3 421-427 Disease denotes cancer http://purl.obolibrary.org/obo/MONDO_0004992
T4 638-644 Disease denotes cancer http://purl.obolibrary.org/obo/MONDO_0004992
T5 1487-1504 Disease denotes pancreatic cancer http://purl.obolibrary.org/obo/MONDO_0005192|http://purl.obolibrary.org/obo/MONDO_0009831
T7 1583-1589 Disease denotes cancer http://purl.obolibrary.org/obo/MONDO_0004992

GlyCosmos15-Glycan

Id Subject Object Predicate Lexical cue image
T1 56-66 Glycan denotes Tn-Antigen https://api.glycosmos.org/wurcs2image/latest/png/binary/G57321FI
T2 56-58 Glycan denotes Tn https://api.glycosmos.org/wurcs2image/latest/png/binary/G57321FI
T3 116-126 Glycan denotes Tn-antigen https://api.glycosmos.org/wurcs2image/latest/png/binary/G57321FI
T4 116-118 Glycan denotes Tn https://api.glycosmos.org/wurcs2image/latest/png/binary/G57321FI
T5 128-130 Glycan denotes Tn https://api.glycosmos.org/wurcs2image/latest/png/binary/G57321FI
T6 165-171 Glycan denotes GalNAc https://api.glycosmos.org/wurcs2image/latest/png/binary/G39738WL
T7 429-431 Glycan denotes Tn https://api.glycosmos.org/wurcs2image/latest/png/binary/G57321FI
T8 530-532 Glycan denotes Tn https://api.glycosmos.org/wurcs2image/latest/png/binary/G57321FI
T9 679-681 Glycan denotes Tn https://api.glycosmos.org/wurcs2image/latest/png/binary/G57321FI
T10 722-724 Glycan denotes Tn https://api.glycosmos.org/wurcs2image/latest/png/binary/G57321FI
T11 752-754 Glycan denotes Tn https://api.glycosmos.org/wurcs2image/latest/png/binary/G57321FI
T12 807-809 Glycan denotes Tn https://api.glycosmos.org/wurcs2image/latest/png/binary/G57321FI
T13 898-900 Glycan denotes Tn https://api.glycosmos.org/wurcs2image/latest/png/binary/G57321FI
T14 992-994 Glycan denotes Tn https://api.glycosmos.org/wurcs2image/latest/png/binary/G57321FI
T15 1008-1010 Glycan denotes Tn https://api.glycosmos.org/wurcs2image/latest/png/binary/G57321FI
T16 1087-1089 Glycan denotes Tn https://api.glycosmos.org/wurcs2image/latest/png/binary/G57321FI
T17 1200-1202 Glycan denotes Tn https://api.glycosmos.org/wurcs2image/latest/png/binary/G57321FI
T18 1321-1323 Glycan denotes Tn https://api.glycosmos.org/wurcs2image/latest/png/binary/G57321FI
T19 1377-1379 Glycan denotes Tn https://api.glycosmos.org/wurcs2image/latest/png/binary/G57321FI
T20 1445-1447 Glycan denotes Tn https://api.glycosmos.org/wurcs2image/latest/png/binary/G57321FI
T21 1517-1519 Glycan denotes Tn https://api.glycosmos.org/wurcs2image/latest/png/binary/G57321FI
T22 1577-1579 Glycan denotes Tn https://api.glycosmos.org/wurcs2image/latest/png/binary/G57321FI
T23 1596-1598 Glycan denotes Tn https://api.glycosmos.org/wurcs2image/latest/png/binary/G57321FI

Glycan-GlyCosmos

Id Subject Object Predicate Lexical cue image
T1 56-66 Glycan denotes Tn-Antigen https://api.glycosmos.org/wurcs2image/latest/png/binary/G57321FI
T2 56-58 Glycan denotes Tn https://api.glycosmos.org/wurcs2image/latest/png/binary/G57321FI
T3 116-126 Glycan denotes Tn-antigen https://api.glycosmos.org/wurcs2image/latest/png/binary/G57321FI
T4 116-118 Glycan denotes Tn https://api.glycosmos.org/wurcs2image/latest/png/binary/G57321FI
T5 128-130 Glycan denotes Tn https://api.glycosmos.org/wurcs2image/latest/png/binary/G57321FI
T6 165-171 Glycan denotes GalNAc https://api.glycosmos.org/wurcs2image/latest/png/binary/G39738WL
T7 429-431 Glycan denotes Tn https://api.glycosmos.org/wurcs2image/latest/png/binary/G57321FI
T8 530-532 Glycan denotes Tn https://api.glycosmos.org/wurcs2image/latest/png/binary/G57321FI
T9 679-681 Glycan denotes Tn https://api.glycosmos.org/wurcs2image/latest/png/binary/G57321FI
T10 722-724 Glycan denotes Tn https://api.glycosmos.org/wurcs2image/latest/png/binary/G57321FI
T11 752-754 Glycan denotes Tn https://api.glycosmos.org/wurcs2image/latest/png/binary/G57321FI
T12 807-809 Glycan denotes Tn https://api.glycosmos.org/wurcs2image/latest/png/binary/G57321FI
T13 898-900 Glycan denotes Tn https://api.glycosmos.org/wurcs2image/latest/png/binary/G57321FI
T14 992-994 Glycan denotes Tn https://api.glycosmos.org/wurcs2image/latest/png/binary/G57321FI
T15 1008-1010 Glycan denotes Tn https://api.glycosmos.org/wurcs2image/latest/png/binary/G57321FI
T16 1087-1089 Glycan denotes Tn https://api.glycosmos.org/wurcs2image/latest/png/binary/G57321FI
T17 1200-1202 Glycan denotes Tn https://api.glycosmos.org/wurcs2image/latest/png/binary/G57321FI
T18 1321-1323 Glycan denotes Tn https://api.glycosmos.org/wurcs2image/latest/png/binary/G57321FI
T19 1377-1379 Glycan denotes Tn https://api.glycosmos.org/wurcs2image/latest/png/binary/G57321FI
T20 1445-1447 Glycan denotes Tn https://api.glycosmos.org/wurcs2image/latest/png/binary/G57321FI
T21 1517-1519 Glycan denotes Tn https://api.glycosmos.org/wurcs2image/latest/png/binary/G57321FI
T22 1577-1579 Glycan denotes Tn https://api.glycosmos.org/wurcs2image/latest/png/binary/G57321FI
T23 1596-1598 Glycan denotes Tn https://api.glycosmos.org/wurcs2image/latest/png/binary/G57321FI

GlyCosmos-GlycoEpitope

Id Subject Object Predicate Lexical cue glycoepitope_id
T1 56-66 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes Tn-Antigen http://www.glycoepitope.jp/epitopes/EP0021
T2 56-58 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes Tn http://www.glycoepitope.jp/epitopes/EP0021
T3 116-126 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes Tn-antigen http://www.glycoepitope.jp/epitopes/EP0021
T4 116-118 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes Tn http://www.glycoepitope.jp/epitopes/EP0021
T5 128-130 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes Tn http://www.glycoepitope.jp/epitopes/EP0021
T6 429-431 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes Tn http://www.glycoepitope.jp/epitopes/EP0021
T7 530-532 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes Tn http://www.glycoepitope.jp/epitopes/EP0021
T8 679-681 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes Tn http://www.glycoepitope.jp/epitopes/EP0021
T9 722-724 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes Tn http://www.glycoepitope.jp/epitopes/EP0021
T10 752-754 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes Tn http://www.glycoepitope.jp/epitopes/EP0021
T11 807-809 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes Tn http://www.glycoepitope.jp/epitopes/EP0021
T12 898-900 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes Tn http://www.glycoepitope.jp/epitopes/EP0021
T13 992-994 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes Tn http://www.glycoepitope.jp/epitopes/EP0021
T14 1008-1010 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes Tn http://www.glycoepitope.jp/epitopes/EP0021
T15 1087-1089 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes Tn http://www.glycoepitope.jp/epitopes/EP0021
T16 1200-1202 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes Tn http://www.glycoepitope.jp/epitopes/EP0021
T17 1321-1323 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes Tn http://www.glycoepitope.jp/epitopes/EP0021
T18 1377-1379 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes Tn http://www.glycoepitope.jp/epitopes/EP0021
T19 1445-1447 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes Tn http://www.glycoepitope.jp/epitopes/EP0021
T20 1517-1519 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes Tn http://www.glycoepitope.jp/epitopes/EP0021
T21 1577-1579 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes Tn http://www.glycoepitope.jp/epitopes/EP0021
T22 1596-1598 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes Tn http://www.glycoepitope.jp/epitopes/EP0021

GlyCosmos15-HP

Id Subject Object Predicate Lexical cue hp_id
T1 243-249 Phenotype denotes cancer HP:0002664
T2 385-391 Phenotype denotes cancer HP:0002664
T3 421-427 Phenotype denotes cancer HP:0002664
T4 638-644 Phenotype denotes cancer HP:0002664
T5 1487-1504 Phenotype denotes pancreatic cancer HP:0002894
T6 1583-1589 Phenotype denotes cancer HP:0002664

GlyCosmos15-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T1 243-249 Disease denotes cancer MONDO:0004992
T2 385-391 Disease denotes cancer MONDO:0004992
T3 421-427 Disease denotes cancer MONDO:0004992
T4 638-644 Disease denotes cancer MONDO:0004992
T5 1487-1504 Disease denotes pancreatic cancer MONDO:0005192|MONDO:0009831
T7 1583-1589 Disease denotes cancer MONDO:0004992

GlyCosmos15-Taxon

Id Subject Object Predicate Lexical cue db_id
T1 1115-1120 Organism denotes human 9606

GlyCosmos15-GlycoEpitope

Id Subject Object Predicate Lexical cue glycoepitope_id
T1 56-66 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes Tn-Antigen http://www.glycoepitope.jp/epitopes/EP0021
T2 56-58 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes Tn http://www.glycoepitope.jp/epitopes/EP0021
T3 116-126 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes Tn-antigen http://www.glycoepitope.jp/epitopes/EP0021
T4 116-118 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes Tn http://www.glycoepitope.jp/epitopes/EP0021
T5 128-130 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes Tn http://www.glycoepitope.jp/epitopes/EP0021
T6 429-431 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes Tn http://www.glycoepitope.jp/epitopes/EP0021
T7 530-532 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes Tn http://www.glycoepitope.jp/epitopes/EP0021
T8 679-681 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes Tn http://www.glycoepitope.jp/epitopes/EP0021
T9 722-724 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes Tn http://www.glycoepitope.jp/epitopes/EP0021
T10 752-754 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes Tn http://www.glycoepitope.jp/epitopes/EP0021
T11 807-809 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes Tn http://www.glycoepitope.jp/epitopes/EP0021
T12 898-900 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes Tn http://www.glycoepitope.jp/epitopes/EP0021
T13 992-994 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes Tn http://www.glycoepitope.jp/epitopes/EP0021
T14 1008-1010 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes Tn http://www.glycoepitope.jp/epitopes/EP0021
T15 1087-1089 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes Tn http://www.glycoepitope.jp/epitopes/EP0021
T16 1200-1202 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes Tn http://www.glycoepitope.jp/epitopes/EP0021
T17 1321-1323 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes Tn http://www.glycoepitope.jp/epitopes/EP0021
T18 1377-1379 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes Tn http://www.glycoepitope.jp/epitopes/EP0021
T19 1445-1447 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes Tn http://www.glycoepitope.jp/epitopes/EP0021
T20 1517-1519 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes Tn http://www.glycoepitope.jp/epitopes/EP0021
T21 1577-1579 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes Tn http://www.glycoepitope.jp/epitopes/EP0021
T22 1596-1598 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes Tn http://www.glycoepitope.jp/epitopes/EP0021

GlyCosmos15-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 735-740 Body_part denotes scale http://purl.obolibrary.org/obo/UBERON_0002542
T2 1121-1124 Body_part denotes gut http://purl.obolibrary.org/obo/UBERON_0001007|http://purl.obolibrary.org/obo/UBERON_0001555|http://purl.obolibrary.org/obo/UBERON_0004907

GlyCosmos15-Sentences

Id Subject Object Predicate Lexical cue
T1 0-115 Sentence denotes Mass Spectrometric Mapping of Glycoproteins Modified by Tn-Antigen Using Solid-Phase Capture and Enzymatic Release.
T2 116-392 Sentence denotes Tn-antigen (Tn), a single N-acetylgalactosamine (GalNAc) monosaccharide attached to protein Ser/Thr residues, is found on most cancer yet rarely detected in adult normal tissues as reported in previous studies, featuring it as one of the most distinctive signatures of cancer.
T3 393-517 Sentence denotes Although it is important in cancer, Tn modified glycoproteins are not entirely clear owing to the lack of a suitable method.
T4 518-801 Sentence denotes Knowing the Tn-glycosylated proteins and glycosylation sites are essential to the prevention, diagnosis, and therapy of cancer associated with the expression of Tn. Here, we introduce a method named EXoO-Tn for large-scale mapping of Tn-glycosylated proteins and glycosylation sites.
T5 802-1053 Sentence denotes EXoO-Tn utilizes solid-phase immobilization of proteolytic peptides of proteins, which modifies Tn by glycosyltransferase C1GalT1 with isotopically labeled UDP-Gal(13C6), to tag and convert Tn to Gal(13C6)-Tn, which gives rise to a unique glycan mass.
T6 1054-1294 Sentence denotes The exquisite Gal(13C6) modified Tn are then recognized by a human-gut-bacterial enzyme, OpeRATOR, and released at the N-termini of the Gal(13C6)-Tn-occupied Ser/Thr residues from immobilized peptides to yield site-containing glycopeptides.
T7 1295-1435 Sentence denotes The effectiveness of EXoO-Tn was benchmarked by analyzing Jurkat cells, where 947 Tn-glycosylation sites from 480 glycoproteins were mapped.
T8 1436-1550 Sentence denotes The EXoO-Tn was further applied to the analysis of pancreatic cancer sera, where Tn-glycoproteins were identified.
T9 1551-1665 Sentence denotes Given the significance of Tn in cancer, EXoO-Tn is anticipated to have broad translational and clinical utilities.

GlyCosmos15-FMA

Id Subject Object Predicate Lexical cue db_id
T1 286-293 Body_part denotes tissues FMA:9637
T2 1121-1124 Body_part denotes gut FMA:7199

GlyCosmos15-MAT

Id Subject Object Predicate Lexical cue mat_id
T1 1121-1124 Body_part denotes gut http://purl.obolibrary.org/obo/MAT_0000043

NCBITAXON

Id Subject Object Predicate Lexical cue db_id
T1 1115-1120 OrganismTaxon denotes human 9606

Anatomy-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 735-740 Body_part denotes scale http://purl.obolibrary.org/obo/UBERON_0002542
T2 1121-1124 Body_part denotes gut http://purl.obolibrary.org/obo/UBERON_0001007|http://purl.obolibrary.org/obo/UBERON_0001555|http://purl.obolibrary.org/obo/UBERON_0004907

HP-phenotype

Id Subject Object Predicate Lexical cue hp_id
T1 243-249 Phenotype denotes cancer HP:0002664
T2 385-391 Phenotype denotes cancer HP:0002664
T3 421-427 Phenotype denotes cancer HP:0002664
T4 638-644 Phenotype denotes cancer HP:0002664
T5 1487-1504 Phenotype denotes pancreatic cancer HP:0002894
T6 1583-1589 Phenotype denotes cancer HP:0002664