Id |
Subject |
Object |
Predicate |
Lexical cue |
T1 |
0-84 |
Sentence |
denotes |
Neuroimmune interaction in seizures and epilepsy: focusing on monocyte infiltration. |
T2 |
85-169 |
Sentence |
denotes |
Epilepsy is a major neurological condition that affects millions of people globally. |
T3 |
170-318 |
Sentence |
denotes |
While a number of interventions have been developed to mitigate this condition, a significant number of patients are refractory to these treatments. |
T4 |
319-370 |
Sentence |
denotes |
Consequently, other avenues of research are needed. |
T5 |
371-551 |
Sentence |
denotes |
One such avenue is modulation of the immune system response to this condition, which has mostly focused on microglia, the resident immune cells of the central nervous system (CNS). |
T6 |
552-706 |
Sentence |
denotes |
However, other immune cells can impact neurological conditions, principally bloodborne monocytes that can infiltrate into brain parenchyma after seizures. |
T7 |
707-867 |
Sentence |
denotes |
As such, this review will first discuss how monocytes can be recruited to the CNS and how they can be distinguished from there immunological cousins, microglia. |
T8 |
868-974 |
Sentence |
denotes |
Then we will explore what is known about the role monocytes have within seizure pathogenesis and epilepsy. |
T9 |
975-1213 |
Sentence |
denotes |
Considering how little is known about monocyte function in seizure and epilepsy related pathologies, further studies are warranted that investigate infiltrated bloodborne monocytes as a potential therapeutic target for epilepsy treatment. |
T1 |
0-84 |
Sentence |
denotes |
Neuroimmune interaction in seizures and epilepsy: focusing on monocyte infiltration. |
T2 |
85-169 |
Sentence |
denotes |
Epilepsy is a major neurological condition that affects millions of people globally. |
T3 |
170-318 |
Sentence |
denotes |
While a number of interventions have been developed to mitigate this condition, a significant number of patients are refractory to these treatments. |
T4 |
319-370 |
Sentence |
denotes |
Consequently, other avenues of research are needed. |
T5 |
371-551 |
Sentence |
denotes |
One such avenue is modulation of the immune system response to this condition, which has mostly focused on microglia, the resident immune cells of the central nervous system (CNS). |
T6 |
552-706 |
Sentence |
denotes |
However, other immune cells can impact neurological conditions, principally bloodborne monocytes that can infiltrate into brain parenchyma after seizures. |
T7 |
707-867 |
Sentence |
denotes |
As such, this review will first discuss how monocytes can be recruited to the CNS and how they can be distinguished from there immunological cousins, microglia. |
T8 |
868-974 |
Sentence |
denotes |
Then we will explore what is known about the role monocytes have within seizure pathogenesis and epilepsy. |
T9 |
975-1213 |
Sentence |
denotes |
Considering how little is known about monocyte function in seizure and epilepsy related pathologies, further studies are warranted that investigate infiltrated bloodborne monocytes as a potential therapeutic target for epilepsy treatment. |