> top > docs > PubMed:32415419 > annotations

PubMed:32415419 JSONTXT

Annnotations TAB JSON ListView MergeView

LitCovid-OGER-BB

Id Subject Object Predicate Lexical cue
T1 42-46 CHEBI:23888;CHEBI:23888 denotes Drug
T2 51-59 SP_7 denotes COVID-19
T3 61-79 CHEBI:5801;DG_20;CHEBI:5801 denotes Hydroxychloroquine
T4 206-216 UBERON:0002405 denotes autoimmune
T5 302-313 CHEBI:23888;CHEBI:23888 denotes medications
T6 348-353 NCBITaxon:10239 denotes viral
T7 365-373 SP_7 denotes COVID-19
T8 655-659 CHEBI:23888;CHEBI:23888 denotes drug
T9 687-695 SP_7 denotes COVID-19
T10 836-845 GO:0005768 denotes endosomal
T11 876-907 PG_10;PR:000003622 denotes angiotensin-converting enzyme 2
T12 911-915 G_3;PG_10;PR:000003622 denotes ACE2
T13 992-1000 SP_7 denotes COVID-19
T14 1138-1147 GO:0006914 denotes autophagy
T15 1162-1169 CL:0000084 denotes T cells
T16 1310-1318 SP_7 denotes COVID-19

hydroxychloroquine

Id Subject Object Predicate Lexical cue hp_id
T1 206-226 Phenotype denotes autoimmune disorders http://purl.obolibrary.org/obo/HP_0002960
T2 237-257 Phenotype denotes rheumatoid arthritis http://purl.obolibrary.org/obo/HP_0001370
T3 262-290 Phenotype denotes systemic lupus erythematosus http://purl.obolibrary.org/obo/HP_0002725

Inflammaging

Id Subject Object Predicate Lexical cue
T1 0-60 Sentence denotes Smooth or Risky Revisit of an Old Malaria Drug for COVID-19?
T2 61-119 Sentence denotes Hydroxychloroquine (HCQ) is an old medication for malaria.
T3 120-332 Sentence denotes In addition to handling this parasitic disease, HCQ is also used to treat a number of autoimmune disorders including rheumatoid arthritis and systemic lupus erythematosus when other medications are not effective.
T4 333-600 Sentence denotes Recently a new viral infection (COVID-19) is rocking the entire world so much that it has already taken more than 200,000 lives throughout the world within the last two months and the World Health Organization was forced to declare it as a pandemic on March 11, 2020.
T5 601-745 Sentence denotes Interestingly, some reports indicate that this wonder drug may be also beneficial for COVID-19 and accordingly, many clinical trials have begun.
T6 746-1008 Sentence denotes Here, we discuss different modes of action (anti-inflammatory, antioxidant, inhibition of endosomal acidification, suppression of angiotensin-converting enzyme 2 or ACE2 glycosylation, etc.) of HCQ that might be responsible for its possible anti-COVID-19 effect.
T7 1009-1319 Sentence denotes On the other hand, this review also makes an honest attempt to delineate mechanisms (increase in vasoconstriction, inhibition of autophagy, depletion of T cells, etc.) indicating how it may aggravate certain conditions and why caution should be taken before granting widespread repurposing of HCQ for COVID-19.
T8 1320-1339 Sentence denotes Graphical Abstract.
T1 0-60 Sentence denotes Smooth or Risky Revisit of an Old Malaria Drug for COVID-19?
T2 61-119 Sentence denotes Hydroxychloroquine (HCQ) is an old medication for malaria.
T3 120-332 Sentence denotes In addition to handling this parasitic disease, HCQ is also used to treat a number of autoimmune disorders including rheumatoid arthritis and systemic lupus erythematosus when other medications are not effective.
T4 333-600 Sentence denotes Recently a new viral infection (COVID-19) is rocking the entire world so much that it has already taken more than 200,000 lives throughout the world within the last two months and the World Health Organization was forced to declare it as a pandemic on March 11, 2020.
T5 601-745 Sentence denotes Interestingly, some reports indicate that this wonder drug may be also beneficial for COVID-19 and accordingly, many clinical trials have begun.
T6 746-1008 Sentence denotes Here, we discuss different modes of action (anti-inflammatory, antioxidant, inhibition of endosomal acidification, suppression of angiotensin-converting enzyme 2 or ACE2 glycosylation, etc.) of HCQ that might be responsible for its possible anti-COVID-19 effect.
T7 1009-1319 Sentence denotes On the other hand, this review also makes an honest attempt to delineate mechanisms (increase in vasoconstriction, inhibition of autophagy, depletion of T cells, etc.) indicating how it may aggravate certain conditions and why caution should be taken before granting widespread repurposing of HCQ for COVID-19.
T8 1320-1339 Sentence denotes Graphical Abstract.