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PubMed:32410772 JSONTXT

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LitCovid-OGER-BB

Id Subject Object Predicate Lexical cue
T1 9-26 CHEBI:52217;CHEBI:52217 denotes pharmacotherapies
T2 31-39 SP_7 denotes COVID-19
T3 47-53 NCBITaxon:11118 denotes Corona
T4 54-59 NCBITaxon:10239 denotes virus
T5 115-127 NCBITaxon:11118 denotes corona virus
T6 189-200 UBERON:0001004 denotes respiratory
T7 391-397 NCBITaxon:9606 denotes people
T8 438-444 GO:0016265 denotes deaths
T9 471-476 NCBITaxon:10239 denotes virus
T10 518-523 CHEBI:23888;CHEBI:23888 denotes drugs
T11 622-630 SP_7 denotes COVID 19
T12 710-721 CHEBI:3638;DG_10;CHEBI:3638 denotes chloroquine
T13 722-731 CHEBI:18367;CHEBI:18367 denotes phosphate
T14 736-754 CHEBI:5801;DG_20;CHEBI:5801 denotes hydroxychloroquine
T15 792-802 DG_28 denotes Remdesivir
T16 804-813 DG_23 denotes Lopinavir
T17 814-823 DG_30 denotes Ritonavir
T18 882-887 CHEBI:23888;CHEBI:23888 denotes drugs
T19 905-911 UBERON:0001969 denotes plasma
T20 1088-1093 NCBITaxon:10239 denotes virus
T21 1135-1146 NCBITaxon:1 denotes individuals
T22 1184-1189 CHEBI:23888;CHEBI:23888 denotes drugs
T23 1208-1219 DG_35 denotes Tocilizumab
T24 1336-1341 PR:000008989 denotes IL-37
T25 1519-1530 CHEBI:23888;CHEBI:23888 denotes medications

hydroxychloroquine

Id Subject Object Predicate Lexical cue hp_id
T1 168-177 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T2 189-209 Phenotype denotes respiratory distress http://purl.obolibrary.org/obo/HP_0002098
T3 1105-1119 Phenotype denotes cytokine storm http://purl.obolibrary.org/obo/HP_0033041

Inflammaging

Id Subject Object Predicate Lexical cue
T1 0-40 Sentence denotes Emerging pharmacotherapies for COVID-19.
T2 41-219 Sentence denotes Novel Corona-virus Disease 2019 (nCOVID 19) is caused by a novel virulent corona virus and leads to potentially fatal virulent pneumonia and severe respiratory distress syndrome.
T3 220-345 Sentence denotes It was initially declared as public health emergency if international concern by WHO followed by Pandemic on 12th March 2020.
T4 346-445 Sentence denotes As of 10th April 2020, more than 1.5 million people are affected globally with around 95000 deaths.
T5 446-631 Sentence denotes Vaccines for this deadly virus are currently under development and many drugs used for other indications have been repurposed and investigated for prophylaxis and treatment of COVID 19.
T6 632-920 Sentence denotes As per SOLIDARITY trial by WHO, some of the most promising candidates include chloroquine phosphate and hydroxychloroquine which are anti-malarial medications, Remdesivir, Lopinavir-Ritonavir combination with or without interferon which are anti-HIV drugs and convalescent plasma therapy.
T7 921-1010 Sentence denotes The current evidence of efficacy and ongoing research has been elaborated in the article.
T8 1011-1147 Sentence denotes Besides, there has been evidence regarding inflammatory pathogenesis of this virus leading to cytokine storm in susceptible individuals.
T9 1148-1284 Sentence denotes Thus, anti-proinflammatory cytokine drugs like Anakinra and Tocilizumab are undergoing multiple trials and some results are encouraging.
T10 1285-1403 Sentence denotes Similarly, use of anti-inflammatory cytokines like IL-37 and IL-38 is hypothesised to be useful and is under research.
T11 1404-1598 Sentence denotes The situation is still evolving and hence there is yet no definitive therapy but to conclude the use of repurposed medications can be a boon till a definitive therapy and vaccines are developed.
T1 0-40 Sentence denotes Emerging pharmacotherapies for COVID-19.
T2 41-219 Sentence denotes Novel Corona-virus Disease 2019 (nCOVID 19) is caused by a novel virulent corona virus and leads to potentially fatal virulent pneumonia and severe respiratory distress syndrome.
T3 220-345 Sentence denotes It was initially declared as public health emergency if international concern by WHO followed by Pandemic on 12th March 2020.
T4 346-445 Sentence denotes As of 10th April 2020, more than 1.5 million people are affected globally with around 95000 deaths.
T5 446-631 Sentence denotes Vaccines for this deadly virus are currently under development and many drugs used for other indications have been repurposed and investigated for prophylaxis and treatment of COVID 19.
T6 632-920 Sentence denotes As per SOLIDARITY trial by WHO, some of the most promising candidates include chloroquine phosphate and hydroxychloroquine which are anti-malarial medications, Remdesivir, Lopinavir-Ritonavir combination with or without interferon which are anti-HIV drugs and convalescent plasma therapy.
T7 921-1010 Sentence denotes The current evidence of efficacy and ongoing research has been elaborated in the article.
T8 1011-1147 Sentence denotes Besides, there has been evidence regarding inflammatory pathogenesis of this virus leading to cytokine storm in susceptible individuals.
T9 1148-1284 Sentence denotes Thus, anti-proinflammatory cytokine drugs like Anakinra and Tocilizumab are undergoing multiple trials and some results are encouraging.
T10 1285-1403 Sentence denotes Similarly, use of anti-inflammatory cytokines like IL-37 and IL-38 is hypothesised to be useful and is under research.
T11 1404-1598 Sentence denotes The situation is still evolving and hence there is yet no definitive therapy but to conclude the use of repurposed medications can be a boon till a definitive therapy and vaccines are developed.