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PubMed:32363402 JSONTXT

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GlyCosmos6-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 285-298 Body_part denotes intracellular http://purl.obolibrary.org/obo/GO_0005622
T2 593-602 Body_part denotes secretion http://purl.obolibrary.org/obo/UBERON_0000456

sentences

Id Subject Object Predicate Lexical cue
T1 0-95 Sentence denotes How glycosylation affects glycosylation: the role of N-glycans in glycosyltransferase activity.
T2 96-185 Sentence denotes N-glycosylation is one of the most important posttranslational modifications of proteins.
T3 186-338 Sentence denotes It plays important roles in the biogenesis and functions of proteins by influencing their folding, intracellular localization, stability and solubility.
T4 339-464 Sentence denotes N-glycans are synthesized by glycosyltransferases, a complex group of ubiquitous enzymes that occur in most kingdoms of life.
T5 465-646 Sentence denotes A growing body of evidence shows that N-glycans may influence processing and functions of glycosyltransferases, including their secretion, stability and substrate/acceptor affinity.
T6 647-734 Sentence denotes Changes in these properties may have a profound impact on glycosyltransferase activity.
T7 735-822 Sentence denotes Indeed, some glycosyltransferases have to be glycosylated themselves for full activity.
T8 823-1078 Sentence denotes N-glycans and glycosyltransferases play roles in the pathogenesis of many diseases (including cancers), so studies on glycosyltransferases may contribute to the development of new therapy methods and novel glycoengineered enzymes with improved properties.
T9 1079-1241 Sentence denotes In this review, we focus on the role of N-glycosylation in the activity of glycosyltransferases and attempt to summarize all available data about this phenomenon.
T1 0-95 Sentence denotes How glycosylation affects glycosylation: the role of N-glycans in glycosyltransferase activity.
T2 96-185 Sentence denotes N-glycosylation is one of the most important posttranslational modifications of proteins.
T3 186-338 Sentence denotes It plays important roles in the biogenesis and functions of proteins by influencing their folding, intracellular localization, stability and solubility.
T4 339-464 Sentence denotes N-glycans are synthesized by glycosyltransferases, a complex group of ubiquitous enzymes that occur in most kingdoms of life.
T5 465-646 Sentence denotes A growing body of evidence shows that N-glycans may influence processing and functions of glycosyltransferases, including their secretion, stability and substrate/acceptor affinity.
T6 647-734 Sentence denotes Changes in these properties may have a profound impact on glycosyltransferase activity.
T7 735-822 Sentence denotes Indeed, some glycosyltransferases have to be glycosylated themselves for full activity.
T8 823-1078 Sentence denotes N-glycans and glycosyltransferases play roles in the pathogenesis of many diseases (including cancers), so studies on glycosyltransferases may contribute to the development of new therapy methods and novel glycoengineered enzymes with improved properties.
T9 1079-1241 Sentence denotes In this review, we focus on the role of N-glycosylation in the activity of glycosyltransferases and attempt to summarize all available data about this phenomenon.

GlyCosmos6-CLO

Id Subject Object Predicate Lexical cue
T1 86-94 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T2 725-733 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T3 813-821 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T4 1098-1103 http://purl.obolibrary.org/obo/CLO_0009985 denotes focus
T5 1142-1150 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity