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LitCovid-OGER-BB

Id Subject Object Predicate Lexical cue
T1 97-103 UBERON:0002113 denotes kidney
T2 137-146 SP_7 denotes SARS-CoV2
T3 173-182 SP_7 denotes SARS-CoV2
T4 225-231 UBERON:0002113 denotes kidney
T5 269-286 CHEBI:35705 denotes immunosuppression
T6 269-286 CHEBI:35705 denotes immunosuppression
T7 314-320 UBERON:0002113 denotes kidney
T8 483-492 SP_7 denotes SARS-CoV2
T9 582-600 CHEBI:12071 denotes methylprednisolone
T10 582-600 DG_36 denotes methylprednisolone
T11 582-600 CHEBI:12071 denotes methylprednisolone
T12 663-681 CHEBI:5801 denotes hydroxychloroquine
T13 663-681 DG_20 denotes hydroxychloroquine
T14 663-681 CHEBI:5801 denotes hydroxychloroquine
T15 706-712 UBERON:0002113 denotes kidney
T16 841-846 UBERON:0001443 denotes chest
T17 1132-1138 UBERON:0002113 denotes kidney
T18 1216-1227 DG_35 denotes tocilizumab
T19 1252-1260 GO:0042571 denotes antibody
T20 1268-1272 PR:000001393 denotes IL-6
T21 1297-1303 UBERON:0002113 denotes kidney
T22 1326-1330 GO:0016265 denotes died
T23 1475-1480 UBERON:0001443 denotes chest
T24 1545-1550 UBERON:0002113 denotes renal
T25 1578-1587 SP_7 denotes SARS-Cov2
T26 1641-1647 UBERON:0002113 denotes kidney
T27 1669-1679 SP_7 denotes SARS-CoV-2

hydroxychloroquine

Id Subject Object Predicate Lexical cue hp_id
T1 147-156 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T2 501-510 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T3 759-764 Phenotype denotes fever http://purl.obolibrary.org/obo/HP_0001945
T4 792-815 Phenotype denotes difficulty in breathing http://purl.obolibrary.org/obo/HP_0002098
T5 1126-1145 Phenotype denotes acute kidney injury http://purl.obolibrary.org/obo/HP_0001919
T6 1588-1597 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T7 1688-1697 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090

Inflammaging

Id Subject Object Predicate Lexical cue
T1 0-157 Sentence denotes A single center observational study of the clinical characteristics and short-term outcome of 20 kidney transplant patients admitted for SARS-CoV2 pneumonia.
T2 158-298 Sentence denotes The outcome of SARS-CoV2 infection in patients who have received a kidney allograft and are being treated with immunosuppression is unclear.
T3 299-511 Sentence denotes We describe 20 kidney transplant recipients (median age 59 years [inter quartile range 51-64 years], median age of transplant 13 years [9-20 years], baseline eGFR 36.5 [23-47.5]) with SARS-CoV2 induced pneumonia.
T4 512-722 Sentence denotes At admission, all had immunosuppression withdrawn and were started on methylprednisolone 16 mg/day, all but one was commenced on antiviral therapy and hydroxychloroquine with doses adjusted for kidney function.
T5 723-816 Sentence denotes At baseline, all patients presented fever but only one complained of difficulty in breathing.
T6 817-959 Sentence denotes Half of patients showed chest radiographic evidence of bilateral infiltrates while the other half showed unilateral changes or no infiltrates.
T7 960-1102 Sentence denotes During a median follow-up of seven days, 87% experienced a radiological progression and among those 73% required escalation of oxygen therapy.
T8 1103-1178 Sentence denotes Six patients developed acute kidney injury with one requiring hemodialysis.
T9 1179-1282 Sentence denotes Six of 12 patients were treated with tocilizumab, a humanized monoclonal antibody to the IL-6 receptor.
T10 1283-1391 Sentence denotes Overall, five kidney transplant recipients died after a median period of 15 days [15-19] from symptom onset.
T11 1392-1598 Sentence denotes These preliminary findings describe a rapid clinical deterioration associated with chest radiographic deterioration and escalating oxygen requirement in renal transplant recipients with SARS-Cov2 pneumonia.
T12 1599-1769 Sentence denotes Thus, in this limited cohort of long-term kidney transplant patients, SARS-CoV-2 induced pneumonia is characterized by high risk of progression and significant mortality.
T1 0-157 Sentence denotes A single center observational study of the clinical characteristics and short-term outcome of 20 kidney transplant patients admitted for SARS-CoV2 pneumonia.
T2 158-298 Sentence denotes The outcome of SARS-CoV2 infection in patients who have received a kidney allograft and are being treated with immunosuppression is unclear.
T3 299-511 Sentence denotes We describe 20 kidney transplant recipients (median age 59 years [inter quartile range 51-64 years], median age of transplant 13 years [9-20 years], baseline eGFR 36.5 [23-47.5]) with SARS-CoV2 induced pneumonia.
T4 512-722 Sentence denotes At admission, all had immunosuppression withdrawn and were started on methylprednisolone 16 mg/day, all but one was commenced on antiviral therapy and hydroxychloroquine with doses adjusted for kidney function.
T5 723-816 Sentence denotes At baseline, all patients presented fever but only one complained of difficulty in breathing.
T6 817-959 Sentence denotes Half of patients showed chest radiographic evidence of bilateral infiltrates while the other half showed unilateral changes or no infiltrates.
T7 960-1102 Sentence denotes During a median follow-up of seven days, 87% experienced a radiological progression and among those 73% required escalation of oxygen therapy.
T8 1103-1178 Sentence denotes Six patients developed acute kidney injury with one requiring hemodialysis.
T9 1179-1282 Sentence denotes Six of 12 patients were treated with tocilizumab, a humanized monoclonal antibody to the IL-6 receptor.
T10 1283-1391 Sentence denotes Overall, five kidney transplant recipients died after a median period of 15 days [15-19] from symptom onset.
T11 1392-1598 Sentence denotes These preliminary findings describe a rapid clinical deterioration associated with chest radiographic deterioration and escalating oxygen requirement in renal transplant recipients with SARS-Cov2 pneumonia.
T12 1599-1769 Sentence denotes Thus, in this limited cohort of long-term kidney transplant patients, SARS-CoV-2 induced pneumonia is characterized by high risk of progression and significant mortality.