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PubMed:32353634 JSONTXT

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LitCovid-OGER-BB

Id	Subject	Object	Predicate	Lexical cue
T1	0-8	SP_7	denotes	COVID-19
T2	54-65	NCBITaxon:11118	denotes	coronavirus
T3	66-75	SP_7	denotes	SARS-CoV2
T4	83-91	SP_7	denotes	COVID-19
T5	167-173	NCBITaxon:9606	denotes	humans
T6	182-187	NCBITaxon:10239	denotes	virus
T7	211-234	GO:0045087	denotes	innate immune responses
T8	218-224	UBERON:0002405	denotes	immune
T9	243-254	GO:0008283	denotes	proliferate
T10	290-297	UBERON:0000479	denotes	tissues
T11	310-320	GO:0008219	denotes	cell death
T12	347-352	GO:0019012	denotes	virus
T13	347-352	NCBITaxon:10239	denotes	virus
T14	367-380	GO:0005622	denotes	intracellular
T15	399-418	GO:0005615	denotes	extracellular space
T16	436-442	UBERON:0002405	denotes	immune
T17	436-447	CL:0000738	denotes	immune cell
T18	479-485	UBERON:0002405	denotes	immune
T19	486-495	GO:0032991	denotes	complexes
T20	532-541	CL:0000576	denotes	monocytes
T21	542-553	CL:0000235	denotes	macrophages
T22	587-593	UBERON:0002405	denotes	immune
T23	587-599	CL:0000738	denotes	immune cells
T24	697-720	CHEBI:67079	denotes	-inflammatory mediators
T25	697-720	CHEBI:67079	denotes	-inflammatory mediators
T26	770-786	CHEBI:22587	denotes	Antiviral agents
T27	770-786	CHEBI:22587	denotes	Antiviral agents
T28	791-797	UBERON:0002405	denotes	immune
T29	798-808	GO:0065007	denotes	modulating
T30	864-870	UBERON:0002405	denotes	immune
T31	864-870	GO:0006955	denotes	immune
T32	893-902	SP_7	denotes	SARS-CoV2
T33	937-943	UBERON:0002405	denotes	immune
T34	937-952	GO:0006955	denotes	immune response
T35	1126-1132	UBERON:0002405	denotes	immune
T36	1133-1143	GO:0065007	denotes	modulating

hydroxychloroquine

Id	Subject	Object	Predicate	Lexical cue	hp_id
T1	745-759	Phenotype	denotes	cytokine storm	http://purl.obolibrary.org/obo/HP_0033041

Inflammaging

Id	Subject	Object	Predicate	Lexical cue
T1	0-9	Sentence	denotes	COVID-19:
T2	10-43	Sentence	denotes	Immunology and treatment options.
T3	44-125	Sentence	denotes	The novel coronavirus SARS-CoV2 causes COVID-19, a pandemic threatening millions.
T4	126-298	Sentence	denotes	As protective immunity does not exist in humans and the virus is capable of escaping innate immune responses, it can proliferate, unhindered, in primarily infected tissues.
T5	299-518	Sentence	denotes	Subsequent cell death results in the release of virus particles and intracellular components to the extracellular space, which result in immune cell recruitment, the generation of immune complexes and associated damage.
T6	519-666	Sentence	denotes	Infection of monocytes/macrophages and/or recruitment of uninfected immune cells can result in massive inflammatory responses later in the disease.
T7	667-769	Sentence	denotes	Uncontrolled production of pro-inflammatory mediators contributes to ARDS and cytokine storm syndrome.
T8	770-849	Sentence	denotes	Antiviral agents and immune modulating treatments are currently being trialled.
T9	850-1151	Sentence	denotes	Understanding immune evasion strategies of SARS-CoV2 and the resulting delayed massive immune response will result in the identification of biomarkers that predict outcomes as well as phenotype and disease stage specific treatments that will likely include both antiviral and immune modulating agents.
T1	0-9	Sentence	denotes	COVID-19:
T2	10-43	Sentence	denotes	Immunology and treatment options.
T3	44-125	Sentence	denotes	The novel coronavirus SARS-CoV2 causes COVID-19, a pandemic threatening millions.
T4	126-298	Sentence	denotes	As protective immunity does not exist in humans and the virus is capable of escaping innate immune responses, it can proliferate, unhindered, in primarily infected tissues.
T5	299-518	Sentence	denotes	Subsequent cell death results in the release of virus particles and intracellular components to the extracellular space, which result in immune cell recruitment, the generation of immune complexes and associated damage.
T6	519-666	Sentence	denotes	Infection of monocytes/macrophages and/or recruitment of uninfected immune cells can result in massive inflammatory responses later in the disease.
T7	667-769	Sentence	denotes	Uncontrolled production of pro-inflammatory mediators contributes to ARDS and cytokine storm syndrome.
T8	770-849	Sentence	denotes	Antiviral agents and immune modulating treatments are currently being trialled.
T9	850-1151	Sentence	denotes	Understanding immune evasion strategies of SARS-CoV2 and the resulting delayed massive immune response will result in the identification of biomarkers that predict outcomes as well as phenotype and disease stage specific treatments that will likely include both antiviral and immune modulating agents.