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LitCovid-OGER-BB

Id Subject Object Predicate Lexical cue
T1 63-73 SP_7 denotes SARS-CoV-2
T2 74-77 GO:0071735 denotes IgM
T3 78-81 GO:0071735 denotes IgG
T4 86-94 GO:0042571 denotes antibody
T5 116-127 NCBITaxon:11118 denotes Coronavirus
T6 157-165 SP_7 denotes COVID-19
T7 343-385 SP_10 denotes severe acute respiratory distress syndrome
T8 356-367 UBERON:0001004 denotes respiratory
T9 570-578 SP_7 denotes COVID-19
T10 622-643 GO:0001171 denotes reverse transcription
T11 683-700 UBERON:0000065 denotes respiratory tract
T12 841-849 SP_7 denotes COVID-19
T13 850-860 GO:0042571 denotes antibodies
T14 867-870 GO:0071735 denotes IgG
T15 875-878 GO:0071735 denotes IgM
T16 1017-1026 SP_7 denotes 2019-nCov
T17 1027-1030 GO:0071735 denotes IgM
T18 1035-1038 GO:0071735 denotes IgG
T19 1230-1235 CHEBI:60004 denotes mixes
T20 1230-1235 CHEBI:60004 denotes mixes
T21 1279-1284 UBERON:0001977 denotes serum
T22 1294-1308 GO:0019814 denotes Immunoglobulin
T23 1356-1361 UBERON:0001977 denotes serum
T24 1397-1405 SP_7 denotes COVID-19
T25 1685-1688 GO:0071735 denotes IgM
T26 1693-1696 GO:0071735 denotes IgG
T27 1843-1851 SP_7 denotes COVID-19
T28 1852-1862 GO:0042571 denotes antibodies
T29 1936-1939 GO:0071735 denotes IgM
T30 1944-1947 GO:0071735 denotes IgG
T31 1987-1990 GO:0071735 denotes IgG
T32 2076-2079 GO:0071735 denotes IgM
T33 2242-2245 GO:0071735 denotes IgM
T34 2250-2253 GO:0071735 denotes IgG
T35 2257-2261 UBERON:0001977 denotes sera
T36 2265-2273 SP_7 denotes COVID-19
T37 2341-2344 GO:0071735 denotes IgM
T38 2349-2352 GO:0071735 denotes IgG
T39 2354-2362 SP_7 denotes COVID-19
T40 2363-2373 GO:0042571 denotes antibodies
T41 2456-2466 GO:0042571 denotes antibodies
T42 2503-2511 SP_7 denotes COVID-19

LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T1 74-77 Body_part denotes IgM http://purl.org/sig/ont/fma/fma62873
T2 78-81 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T3 86-94 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T4 683-700 Body_part denotes respiratory tract http://purl.org/sig/ont/fma/fma265130
T5 867-870 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T6 875-878 Body_part denotes IgM http://purl.org/sig/ont/fma/fma62873
T7 1027-1030 Body_part denotes IgM http://purl.org/sig/ont/fma/fma62873
T8 1035-1038 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T9 1156-1158 Body_part denotes A3 http://purl.org/sig/ont/fma/fma66599
T10 1279-1284 Body_part denotes serum http://purl.org/sig/ont/fma/fma63083
T11 1294-1308 Body_part denotes Immunoglobulin http://purl.org/sig/ont/fma/fma62871
T12 1356-1361 Body_part denotes serum http://purl.org/sig/ont/fma/fma63083
T13 1573-1575 Body_part denotes A3 http://purl.org/sig/ont/fma/fma66599
T14 1685-1688 Body_part denotes IgM http://purl.org/sig/ont/fma/fma62873
T15 1693-1696 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T16 1936-1939 Body_part denotes IgM http://purl.org/sig/ont/fma/fma62873
T17 1944-1947 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T18 1987-1990 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T19 2076-2079 Body_part denotes IgM http://purl.org/sig/ont/fma/fma62873
T20 2242-2245 Body_part denotes IgM http://purl.org/sig/ont/fma/fma62873
T21 2250-2253 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T22 2341-2344 Body_part denotes IgM http://purl.org/sig/ont/fma/fma62873
T23 2349-2352 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872

LitCovid-PD-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 683-700 Body_part denotes respiratory tract http://purl.obolibrary.org/obo/UBERON_0000065
T2 1279-1284 Body_part denotes serum http://purl.obolibrary.org/obo/UBERON_0001977
T3 1356-1361 Body_part denotes serum http://purl.obolibrary.org/obo/UBERON_0001977

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T1 63-71 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T2 116-140 Disease denotes Coronavirus disease 2019 http://purl.obolibrary.org/obo/MONDO_0100096
T3 157-165 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T4 350-385 Disease denotes acute respiratory distress syndrome http://purl.obolibrary.org/obo/MONDO_0006502
T5 356-385 Disease denotes respiratory distress syndrome http://purl.obolibrary.org/obo/MONDO_0009971
T6 387-391 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T7 570-578 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T8 841-849 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T9 1397-1405 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T10 1843-1851 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T11 2265-2273 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T12 2354-2362 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T13 2503-2511 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T1 27-28 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T2 253-256 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T3 509-514 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tests
T4 520-521 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T5 1156-1158 http://purl.obolibrary.org/obo/CLO_0001577 denotes A3
T6 1344-1345 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T7 1573-1575 http://purl.obolibrary.org/obo/CLO_0001577 denotes A3
T8 1911-1912 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T9 2396-2397 http://purl.obolibrary.org/obo/CLO_0001020 denotes a

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T1 592-596 Chemical denotes gold http://purl.obolibrary.org/obo/CHEBI_29287|http://purl.obolibrary.org/obo/CHEBI_30050

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T1 356-376 Phenotype denotes respiratory distress http://purl.obolibrary.org/obo/HP_0002098

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T1 622-643 http://purl.obolibrary.org/obo/GO_0001171 denotes reverse transcription
T2 630-643 http://purl.obolibrary.org/obo/GO_0006351 denotes transcription

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
16 116-140 Disease denotes Coronavirus disease 2019 MESH:C000657245
17 157-165 Disease denotes COVID-19 MESH:C000657245
18 350-385 Disease denotes acute respiratory distress syndrome MESH:D012128
19 387-391 Disease denotes ARDS MESH:D012128
20 409-417 Species denotes patients Tax:9606
21 570-578 Disease denotes COVID-19 MESH:C000657245
22 841-849 Disease denotes COVID-19 MESH:C000657245
23 1017-1026 Species denotes 2019-nCov Tax:2697049
24 1397-1405 Disease denotes COVID-19 MESH:C000657245
25 1415-1423 Species denotes patients Tax:9606
26 1843-1851 Disease denotes COVID-19 MESH:C000657245
27 2265-2273 Disease denotes COVID-19 MESH:C000657245
28 2274-2282 Species denotes patients Tax:9606
29 2354-2362 Disease denotes COVID-19 MESH:C000657245
30 2503-2511 Disease denotes COVID-19 MESH:C000657245
31 2512-2520 Species denotes patients Tax:9606

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T1 0-104 Sentence denotes Analytical performances of a chemiluminescence immunoassay for SARS-CoV-2 IgM/IgG and antibody kinetics.
T2 105-285 Sentence denotes Background Coronavirus disease 2019, abbreviated to COVID-19, represents an emerging health threat worldwide as, after initial reports in China, it has continued to spread rapidly.
T3 286-393 Sentence denotes The clinical spectrum of the disease varies from mild to severe acute respiratory distress syndrome (ARDS).
T4 394-497 Sentence denotes Moreover, many patients can be asymptomatic, thus increasing the uncertainty of the diagnostic work-up.
T5 498-711 Sentence denotes Laboratory tests play a pivotal role in the diagnosis and management of COVID-19, the current gold standard being real-time reverse transcription polymerase chain reaction (rRT-PCR) on respiratory tract specimens.
T6 712-812 Sentence denotes However, the diagnostic accuracy of rRT-PCR depends on many pre-analytical and analytical variables.
T7 813-966 Sentence denotes The measurement of specific COVID-19 antibodies (both IgG and IgM) should serve as an additional, non-invasive tool for disease detection and management.
T8 967-1168 Sentence denotes Methods The imprecision of the MAGLUMI™ 2000 Plus 2019-nCov IgM and IgG assays (Snibe, Shenzhen, China) was assessed by adopting the Clinical and Laboratory Standards Institute (CLSI) EP15-A3 protocol.
T9 1169-1293 Sentence denotes Linearity of dilution and recovery was evaluated by means of mixes of high-level pools and low-level pools of serum samples.
T10 1294-1474 Sentence denotes Immunoglobulin time kinetics were evaluated using a series of serum samples, repeatedly collected from COVID-19-positive patients at different times, from <5 days up to 26-30 days.
T11 1475-1753 Sentence denotes Results Findings at the analytical validation of the assay carried out according to the CLSI EP15-A3 guideline demonstrated that imprecision and repeatability were acceptable (repeatability was <4% and <6% for IgM and IgG, respectively, whilst intermediate imprecision was <6%).
T12 1754-1826 Sentence denotes In addition, results of dilution and recovery studies were satisfactory.
T13 1827-1986 Sentence denotes The kinetics of COVID-19 antibodies confirmed previously reported findings, showing a rapid increase of both IgM and IgG after 6-7 days from the symptom onset.
T14 1987-2109 Sentence denotes IgG had 100% sensitivity on day 12, whilst 88% was the higher positive rate achieved for IgM after the same time interval.
T15 2110-2374 Sentence denotes Conclusions The findings of this study demonstrate the validity of the MAGLUMI 2000 Plus CLIA assay for the measurement of specific IgM and IgG in sera of COVID-19 patients, and for obtaining valuable data on the kinetics of both (IgM and IgG) COVID-19 antibodies.
T16 2375-2521 Sentence denotes These data represent a pre-requisite for the appropriate utilization of specific antibodies for the diagnosis and management of COVID-19 patients.