PubMed:32301155
Annnotations
LitCovid-OGER-BB
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-8 | SP_7 | denotes | COVID-19 |
| T2 | 18-23 | UBERON:0000062 | denotes | organ |
| T3 | 144-155 | NCBITaxon:11118 | denotes | coronavirus |
| T4 | 170-178 | SP_7 | denotes | COVID-19 |
| T5 | 190-237 | SP_7 | denotes | severe acute respiratory syndrome coronavirus 2 |
| T6 | 203-214 | UBERON:0001004 | denotes | respiratory |
| T7 | 239-249 | SP_7 | denotes | SARS-CoV-2 |
| T8 | 263-268 | UBERON:0000062 | denotes | organ |
| T9 | 352-358 | UBERON:0002113 | denotes | kidney |
| T10 | 368-373 | UBERON:0002107 | denotes | liver |
| T11 | 387-392 | UBERON:0000948 | denotes | heart |
| T12 | 428-436 | SP_7 | denotes | COVID-19 |
| T13 | 750-759 | CHEBI:31781 | denotes | Lopinavir |
| T14 | 750-759 | DG_23 | denotes | Lopinavir |
| T15 | 750-759 | CHEBI:31781 | denotes | Lopinavir |
| T16 | 760-769 | CHEBI:45409 | denotes | ritonavir |
| T17 | 760-769 | DG_30 | denotes | ritonavir |
| T18 | 760-769 | CHEBI:45409 | denotes | ritonavir |
| T19 | 795-813 | CHEBI:5801 | denotes | hydroxychloroquine |
| T20 | 795-813 | DG_20 | denotes | hydroxychloroquine |
| T21 | 795-813 | CHEBI:5801 | denotes | hydroxychloroquine |
| T22 | 932-950 | CHEBI:5801 | denotes | hydroxychloroquine |
| T23 | 932-950 | DG_20 | denotes | hydroxychloroquine |
| T24 | 932-950 | CHEBI:5801 | denotes | hydroxychloroquine |
| T25 | 975-987 | PR:000024939 | denotes | interferon-β |
| T26 | 1157-1168 | UBERON:0001004 | denotes | respiratory |
| T27 | 1282-1300 | PR:000005897 | denotes | C-reactive protein |
| T28 | 1457-1467 | SP_7 | denotes | SARS-CoV-2 |
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T1 | 12-23 | Body_part | denotes | solid organ | http://purl.org/sig/ont/fma/fma55670 |
| T2 | 257-268 | Body_part | denotes | solid organ | http://purl.org/sig/ont/fma/fma55670 |
| T3 | 352-358 | Body_part | denotes | kidney | http://purl.org/sig/ont/fma/fma7203 |
| T4 | 368-373 | Body_part | denotes | liver | http://purl.org/sig/ont/fma/fma7197 |
| T5 | 387-392 | Body_part | denotes | heart | http://purl.org/sig/ont/fma/fma7088 |
| T6 | 1293-1300 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
LitCovid-PD-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 18-23 | Body_part | denotes | organ | http://purl.obolibrary.org/obo/UBERON_0000062 |
| T2 | 263-268 | Body_part | denotes | organ | http://purl.obolibrary.org/obo/UBERON_0000062 |
| T3 | 352-358 | Body_part | denotes | kidney | http://purl.obolibrary.org/obo/UBERON_0002113 |
| T4 | 368-373 | Body_part | denotes | liver | http://purl.obolibrary.org/obo/UBERON_0002107 |
| T5 | 387-392 | Body_part | denotes | heart | http://purl.obolibrary.org/obo/UBERON_0000948 |
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T1 | 0-8 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T2 | 144-168 | Disease | denotes | coronavirus disease 2019 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T3 | 170-178 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T4 | 190-237 | Disease | denotes | severe acute respiratory syndrome coronavirus 2 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T5 | 190-223 | Disease | denotes | severe acute respiratory syndrome | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T6 | 239-247 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T7 | 428-436 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T8 | 1157-1176 | Disease | denotes | respiratory failure | http://purl.obolibrary.org/obo/MONDO_0021113 |
| T9 | 1457-1465 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T10 | 1468-1477 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 18-23 | http://purl.obolibrary.org/obo/UBERON_0003103 | denotes | organ |
| T2 | 47-48 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T3 | 263-268 | http://purl.obolibrary.org/obo/UBERON_0003103 | denotes | organ |
| T4 | 344-346 | http://purl.obolibrary.org/obo/CLO_0050510 | denotes | 18 |
| T5 | 352-358 | http://purl.obolibrary.org/obo/UBERON_0002113 | denotes | kidney |
| T6 | 352-358 | http://www.ebi.ac.uk/efo/EFO_0000927 | denotes | kidney |
| T7 | 352-358 | http://www.ebi.ac.uk/efo/EFO_0000929 | denotes | kidney |
| T8 | 368-373 | http://purl.obolibrary.org/obo/UBERON_0002107 | denotes | liver |
| T9 | 368-373 | http://www.ebi.ac.uk/efo/EFO_0000887 | denotes | liver |
| T10 | 387-392 | http://purl.obolibrary.org/obo/UBERON_0000948 | denotes | heart |
| T11 | 387-392 | http://purl.obolibrary.org/obo/UBERON_0007100 | denotes | heart |
| T12 | 387-392 | http://purl.obolibrary.org/obo/UBERON_0015228 | denotes | heart |
| T13 | 387-392 | http://www.ebi.ac.uk/efo/EFO_0000815 | denotes | heart |
| T14 | 458-459 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T15 | 1048-1050 | http://purl.obolibrary.org/obo/CLO_0050510 | denotes | 18 |
| T16 | 1059-1060 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T17 | 1081-1083 | http://purl.obolibrary.org/obo/CLO_0050510 | denotes | 18 |
| T18 | 1250-1254 | http://purl.obolibrary.org/obo/CLO_0001001 | denotes | 8/13 |
| T19 | 1478-1481 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
| T20 | 1482-1483 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T1 | 750-759 | Chemical | denotes | Lopinavir | http://purl.obolibrary.org/obo/CHEBI_31781 |
| T2 | 760-769 | Chemical | denotes | ritonavir | http://purl.obolibrary.org/obo/CHEBI_45409 |
| T3 | 795-813 | Chemical | denotes | hydroxychloroquine | http://purl.obolibrary.org/obo/CHEBI_5801 |
| T4 | 904-913 | Chemical | denotes | antiviral | http://purl.obolibrary.org/obo/CHEBI_22587 |
| T5 | 932-950 | Chemical | denotes | hydroxychloroquine | http://purl.obolibrary.org/obo/CHEBI_5801 |
| T6 | 975-985 | Chemical | denotes | interferon | http://purl.obolibrary.org/obo/CHEBI_52999 |
| T7 | 1293-1300 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
LitCovid-PD-HP
| Id | Subject | Object | Predicate | Lexical cue | hp_id |
|---|---|---|---|---|---|
| T1 | 600-605 | Phenotype | denotes | Fever | http://purl.obolibrary.org/obo/HP_0001945 |
| T2 | 1145-1176 | Phenotype | denotes | progressive respiratory failure | http://purl.obolibrary.org/obo/HP_0002093 |
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 1 | 0-8 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 16 | 144-168 | Disease | denotes | coronavirus disease 2019 | MESH:C000657245 |
| 17 | 170-178 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 18 | 190-237 | Species | denotes | severe acute respiratory syndrome coronavirus 2 | Tax:2697049 |
| 19 | 239-249 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
| 20 | 428-436 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 21 | 600-605 | Disease | denotes | Fever | MESH:D005334 |
| 22 | 750-769 | Chemical | denotes | Lopinavir/ritonavir | MESH:C558899 |
| 23 | 795-813 | Chemical | denotes | hydroxychloroquine | MESH:D006886 |
| 24 | 836-844 | Species | denotes | patients | Tax:9606 |
| 25 | 932-950 | Chemical | denotes | hydroxychloroquine | MESH:D006886 |
| 26 | 975-987 | Gene | denotes | interferon-β | Gene:3456 |
| 27 | 1157-1176 | Disease | denotes | respiratory failure | MESH:D012131 |
| 28 | 1282-1300 | Gene | denotes | C-reactive protein | Gene:1401 |
| 29 | 1457-1477 | Disease | denotes | SARS-CoV-2 infection | MESH:C000657245 |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-46 | Sentence | denotes | COVID-19 in solid organ transplant recipients: |
| T2 | 47-86 | Sentence | denotes | A single-center case series from Spain. |
| T3 | 87-301 | Sentence | denotes | The clinical characteristics, management, and outcome of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) after solid organ transplant (SOT) remain unknown. |
| T4 | 302-491 | Sentence | denotes | We report our preliminary experience with 18 SOT (kidney [44.4%], liver [33.3%], and heart [22.2%]) recipients diagnosed with COVID-19 by March 23, 2020 at a tertiary-care center at Madrid. |
| T5 | 492-599 | Sentence | denotes | Median age at diagnosis was 71.0 ± 12.8 years, and the median interval since transplantation was 9.3 years. |
| T6 | 600-749 | Sentence | denotes | Fever (83.3%) and radiographic abnormalities in form of unilateral or bilateral/multifocal consolidations (72.2%) were the most common presentations. |
| T7 | 750-897 | Sentence | denotes | Lopinavir/ritonavir (usually associated with hydroxychloroquine) was used in 50.0% of patients and had to be prematurely discontinued in 2 of them. |
| T8 | 898-996 | Sentence | denotes | Other antiviral regimens included hydroxychloroquine monotherapy (27.8%) and interferon-β (16.7%). |
| T9 | 997-1052 | Sentence | denotes | As of April 4, the case-fatality rate was 27.8% (5/18). |
| T10 | 1053-1281 | Sentence | denotes | After a median follow-up of 18 days from symptom onset, 30.8% (4/13) of survivors developed progressive respiratory failure, 7.7% (1/13) showed stable clinical condition or improvement, and 61.5% (8/13) had been discharged home. |
| T11 | 1282-1405 | Sentence | denotes | C-reactive protein levels at various points were significantly higher among recipients who experienced unfavorable outcome. |
| T12 | 1406-1516 | Sentence | denotes | In conclusion, this frontline report suggests that SARS-CoV-2 infection has a severe course in SOT recipients. |
hydroxychloroquine
| Id | Subject | Object | Predicate | Lexical cue | hp_id |
|---|---|---|---|---|---|
| T1 | 600-605 | Phenotype | denotes | Fever | http://purl.obolibrary.org/obo/HP_0001945 |
| T2 | 1145-1176 | Phenotype | denotes | progressive respiratory failure | http://purl.obolibrary.org/obo/HP_0002093 |