PubMed:32277836
Annnotations
LitCovid-OGER-BB
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 7-15 | SP_7 | denotes | COVID-19 |
| T2 | 111-119 | SP_7 | denotes | COVID-19 |
| T3 | 199-212 | UBERON:0002405 | denotes | immune system |
| T4 | 216-223 | GO:0065007 | denotes | control |
| T5 | 228-233 | NCBITaxon:10239 | denotes | virus |
| T6 | 262-270 | SP_7 | denotes | COVID-19 |
| T7 | 503-511 | SP_7 | denotes | COVID-19 |
| T8 | 665-671 | UBERON:0000310 | denotes | breast |
| T9 | 756-764 | UBERON:0001637 | denotes | arterial |
| T10 | 811-820 | DG_13 | denotes | darunavir |
| T11 | 821-831 | DG_40 | denotes | cobicistat |
| T12 | 836-854 | DG_20 | denotes | hydroxychloroquine |
| T13 | 836-854 | CHEBI:5801 | denotes | hydroxychloroquine |
| T14 | 836-854 | CHEBI:5801 | denotes | hydroxychloroquine |
| T15 | 1166-1174 | SP_7 | denotes | COVID-19 |
| T16 | 1235-1241 | UBERON:0002405 | denotes | immune |
| T17 | 1235-1250 | GO:0006955 | denotes | immune response |
| T18 | 1312-1322 | GO:0065007 | denotes | controlled |
| T19 | 1341-1347 | UBERON:0002405 | denotes | immune |
| T20 | 1366-1376 | SP_7 | denotes | SARS CoV-2 |
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T1 | 199-212 | Body_part | denotes | immune system | http://purl.org/sig/ont/fma/fma9825 |
| T2 | 665-671 | Body_part | denotes | breast | http://purl.org/sig/ont/fma/fma9601 |
LitCovid-PD-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 199-212 | Body_part | denotes | immune system | http://purl.obolibrary.org/obo/UBERON_0002405 |
| T2 | 665-671 | Body_part | denotes | breast | http://purl.obolibrary.org/obo/UBERON_0000310 |
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T1 | 7-15 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T2 | 40-46 | Disease | denotes | cancer | http://purl.obolibrary.org/obo/MONDO_0004992 |
| T3 | 88-107 | Disease | denotes | Respiratory failure | http://purl.obolibrary.org/obo/MONDO_0021113 |
| T4 | 111-119 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T5 | 262-270 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T6 | 503-511 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T7 | 665-678 | Disease | denotes | breast cancer | http://purl.obolibrary.org/obo/MONDO_0007254 |
| T8 | 672-678 | Disease | denotes | cancer | http://purl.obolibrary.org/obo/MONDO_0004992 |
| T9 | 765-777 | Disease | denotes | hypertension | http://purl.obolibrary.org/obo/MONDO_0005044 |
| T10 | 1166-1174 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T11 | 1366-1370 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T12 | 1377-1386 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 70-71 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T2 | 123-124 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T3 | 159-162 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
| T4 | 182-183 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T5 | 199-212 | http://purl.obolibrary.org/obo/UBERON_0002405 | denotes | immune system |
| T6 | 228-233 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T7 | 351-352 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T8 | 569-570 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T9 | 586-587 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T10 | 665-671 | http://purl.obolibrary.org/obo/UBERON_0000310 | denotes | breast |
| T11 | 732-733 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T12 | 756-764 | http://purl.obolibrary.org/obo/UBERON_0001637 | denotes | arterial |
| T13 | 756-764 | http://www.ebi.ac.uk/efo/EFO_0000814 | denotes | arterial |
| T14 | 1221-1222 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T15 | 1310-1311 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T1 | 623-634 | Chemical | denotes | fulvestrant | http://purl.obolibrary.org/obo/CHEBI_31638 |
| T2 | 811-820 | Chemical | denotes | darunavir | http://purl.obolibrary.org/obo/CHEBI_367163 |
| T3 | 821-831 | Chemical | denotes | cobicistat | http://purl.obolibrary.org/obo/CHEBI_72291 |
| T4 | 836-854 | Chemical | denotes | hydroxychloroquine | http://purl.obolibrary.org/obo/CHEBI_5801 |
LitCovid-PD-HP
| Id | Subject | Object | Predicate | Lexical cue | hp_id |
|---|---|---|---|---|---|
| T1 | 40-46 | Phenotype | denotes | cancer | http://purl.obolibrary.org/obo/HP_0002664 |
| T2 | 88-107 | Phenotype | denotes | Respiratory failure | http://purl.obolibrary.org/obo/HP_0002878 |
| T3 | 467-475 | Phenotype | denotes | dyspnoea | http://purl.obolibrary.org/obo/HP_0002094 |
| T4 | 480-485 | Phenotype | denotes | fever | http://purl.obolibrary.org/obo/HP_0001945 |
| T5 | 665-678 | Phenotype | denotes | breast cancer | http://purl.obolibrary.org/obo/HP_0003002 |
| T6 | 765-777 | Phenotype | denotes | hypertension | http://purl.obolibrary.org/obo/HP_0000822 |
LitCovid-PD-GO-BP
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 1235-1250 | http://purl.obolibrary.org/obo/GO_0006955 | denotes | immune response |
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 3 | 7-15 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 4 | 40-46 | Disease | denotes | cancer | MESH:D009369 |
| 5 | 47-54 | Species | denotes | patient | Tax:9606 |
| 24 | 88-107 | Disease | denotes | Respiratory failure | MESH:D012131 |
| 25 | 111-119 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 26 | 262-270 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 27 | 302-307 | Species | denotes | women | Tax:9606 |
| 28 | 467-475 | Disease | denotes | dyspnoea | MESH:D004417 |
| 29 | 480-485 | Disease | denotes | fever | MESH:D005334 |
| 30 | 503-511 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 31 | 523-530 | Species | denotes | patient | Tax:9606 |
| 32 | 639-650 | Chemical | denotes | abemaciclid | |
| 33 | 665-678 | Disease | denotes | breast cancer | MESH:D001943 |
| 34 | 693-700 | Species | denotes | patient | Tax:9606 |
| 35 | 765-777 | Disease | denotes | hypertension | MESH:D006973 |
| 36 | 784-792 | Species | denotes | patients | Tax:9606 |
| 37 | 811-820 | Chemical | denotes | darunavir | MESH:D000069454 |
| 38 | 821-831 | Chemical | denotes | cobicistat | MESH:D000069547 |
| 39 | 836-854 | Chemical | denotes | hydroxychloroquine | MESH:D006886 |
| 40 | 1166-1174 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 41 | 1371-1386 | Disease | denotes | CoV-2 infection | MESH:C000657245 |
hydroxychloroquine
| Id | Subject | Object | Predicate | Lexical cue | hp_id |
|---|---|---|---|---|---|
| T1 | 40-46 | Phenotype | denotes | cancer | http://purl.obolibrary.org/obo/HP_0002664 |
| T2 | 88-107 | Phenotype | denotes | Respiratory failure | http://purl.obolibrary.org/obo/HP_0002878 |
| T3 | 467-475 | Phenotype | denotes | dyspnoea | http://purl.obolibrary.org/obo/HP_0002094 |
| T4 | 480-485 | Phenotype | denotes | fever | http://purl.obolibrary.org/obo/HP_0001945 |
| T5 | 665-678 | Phenotype | denotes | breast cancer | http://purl.obolibrary.org/obo/HP_0003002 |
| T6 | 765-777 | Phenotype | denotes | hypertension | http://purl.obolibrary.org/obo/HP_0000822 |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-87 | Sentence | denotes | Benign COVID-19 in an immunocompromised cancer patient - the case of a married couple. |
| T2 | 88-234 | Sentence | denotes | Respiratory failure in COVID-19 is a common feature in fatal cases and has been considered as a failure of the immune system to control the virus. |
| T3 | 235-350 | Sentence | denotes | Here we report the case of COVID-19 affecting an immunocompromised women and her presumably immunocompetent spouse. |
| T4 | 351-512 | Sentence | denotes | A married couple (age 60 years) was simultaneously admitted to the emergency department on 10 March 2020 because of dyspnoea and fever, consistent with COVID-19. |
| T5 | 513-778 | Sentence | denotes | The wife (patient 1) was partially immunocompromised as a consequence of a recently started chemotherapy with fulvestrant and abemaciclid for recurring breast cancer, her husband (patient 2) had been healthy except for a history of controlled arterial hypertension. |
| T6 | 779-855 | Sentence | denotes | Both patients were treated with darunavir/cobicistat and hydroxychloroquine. |
| T7 | 856-952 | Sentence | denotes | The clinical course of the immunocompromised partner was benign, without need of intensive care. |
| T8 | 953-1013 | Sentence | denotes | She was able to leave the hospital on day 6 after admission. |
| T9 | 1014-1123 | Sentence | denotes | In contrast, her husband needed intensive care and his recovery was slow, although eventually successful too. |
| T10 | 1124-1387 | Sentence | denotes | These findings suggest that the course of COVID-19 is not necessarily ominous in the presence of a compromised immune response and tend to reinforce the emerging therapeutic concepts of a controlled mitigation of the immune cascade following SARS CoV-2 infection. |