PubMed:32277065 / 0-111 JSON TXT

Halting coronavirus polymerase. The nucleotide analogue remdesivir is an investigational drug for the treatment of human coronavirus infection. Remdesivir is a phosphoramidate prodrug and is known to target viral RNA-dependent RNA polymerases. In this issue, Gordon et al. identify that remdesivir acts as a delayed RNA chain terminator for MERS-CoV polymerase complexes.

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LitCovid-OGER-BB (4) LitCovid-PD-FMA-UBERON (1) LitCovid-PD-CHEBI (3) LitCovid-PubTator (2) sentences (1) LitCovid-sentences (1)

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PubMed:32277065 / 0-111 JSONTXT

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