PubMed:3208248
Annnotations
GlyCosmos6-Glycan-Motif-Image
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 39-42 | Glycan_Motif | denotes | GM3 | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G91237TK|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G56516VH |
| T3 | 89-92 | Glycan_Motif | denotes | GM3 | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G91237TK|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G56516VH |
| T5 | 150-153 | Glycan_Motif | denotes | GM3 | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G91237TK|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G56516VH |
| T7 | 327-330 | Glycan_Motif | denotes | GM3 | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G91237TK|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G56516VH |
| T9 | 378-381 | Glycan_Motif | denotes | GM3 | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G91237TK|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G56516VH |
| T11 | 405-408 | Glycan_Motif | denotes | GM3 | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G91237TK|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G56516VH |
| T13 | 420-423 | Glycan_Motif | denotes | GM3 | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G91237TK|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G56516VH |
| T15 | 442-445 | Glycan_Motif | denotes | GM3 | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G91237TK|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G56516VH |
| T17 | 481-484 | Glycan_Motif | denotes | GM3 | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G91237TK|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G56516VH |
| T19 | 644-655 | Glycan_Motif | denotes | sialic acid | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G81533KY |
GlyCosmos6-Glycan-Motif-Structure
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 39-42 | https://glytoucan.org/Structures/Glycans/G56516VH | denotes | GM3 |
| T2 | 39-42 | https://glytoucan.org/Structures/Glycans/G91237TK | denotes | GM3 |
| T3 | 89-92 | https://glytoucan.org/Structures/Glycans/G56516VH | denotes | GM3 |
| T4 | 89-92 | https://glytoucan.org/Structures/Glycans/G91237TK | denotes | GM3 |
| T5 | 150-153 | https://glytoucan.org/Structures/Glycans/G56516VH | denotes | GM3 |
| T6 | 150-153 | https://glytoucan.org/Structures/Glycans/G91237TK | denotes | GM3 |
| T7 | 327-330 | https://glytoucan.org/Structures/Glycans/G56516VH | denotes | GM3 |
| T8 | 327-330 | https://glytoucan.org/Structures/Glycans/G91237TK | denotes | GM3 |
| T9 | 378-381 | https://glytoucan.org/Structures/Glycans/G56516VH | denotes | GM3 |
| T10 | 378-381 | https://glytoucan.org/Structures/Glycans/G91237TK | denotes | GM3 |
| T11 | 405-408 | https://glytoucan.org/Structures/Glycans/G56516VH | denotes | GM3 |
| T12 | 405-408 | https://glytoucan.org/Structures/Glycans/G91237TK | denotes | GM3 |
| T13 | 420-423 | https://glytoucan.org/Structures/Glycans/G56516VH | denotes | GM3 |
| T14 | 420-423 | https://glytoucan.org/Structures/Glycans/G91237TK | denotes | GM3 |
| T15 | 442-445 | https://glytoucan.org/Structures/Glycans/G56516VH | denotes | GM3 |
| T16 | 442-445 | https://glytoucan.org/Structures/Glycans/G91237TK | denotes | GM3 |
| T17 | 481-484 | https://glytoucan.org/Structures/Glycans/G56516VH | denotes | GM3 |
| T18 | 481-484 | https://glytoucan.org/Structures/Glycans/G91237TK | denotes | GM3 |
| T19 | 644-655 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | sialic acid |
sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| TextSentencer_T1 | 0-141 | Sentence | denotes | Synthesis and characterization of lyso-GM3 (II3Neu5Ac Lactosyl sphingosine), de-N-acetyl-GM3 (II3NeuNH2 lactosyl Cer), and related compounds. |
| TextSentencer_T2 | 142-264 | Sentence | denotes | Various GM3 derivatives which are present in A431 cells have different effects on the activity of the EGF receptor kinase. |
| TextSentencer_T3 | 265-515 | Sentence | denotes | In order to systematically study these effects, the following GM3 derivatives have been synthesized: de-N-acetyl-GM3 (D1), de-N-acetyl-lyso-GM3 (D2), lyso-GM3 (D3), de-N-acetyl-GM3 with N-acetylsphingosine (D4), and GM3 with N-acetylsphingosine (D3). |
| TextSentencer_T4 | 516-685 | Sentence | denotes | A crucial step for the preparation of D1 is the use of mild alkaline conditions of hydrolysis under which the N-acetyl group of sialic acid is preferentially hydrolyzed. |
| TextSentencer_T5 | 686-1104 | Sentence | denotes | For the preparation of D3, conditions which allowed preferential N-acetylation of the amino group of the neuraminic acid moiety were devised, i.e., D2 was incorporated in a dipalmitoyl-phosphatidylcholine (dpPC) liposome in which the sphingosine moiety was protected and the amino group of neuraminic acid was N-acetylated with acetate and a water-soluble catalyst, 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide (DEC). |
| TextSentencer_T6 | 1105-1310 | Sentence | denotes | When an aqueous micellar solution of D2 was treated with acetic anhydride and sodium hydrogencarbonate, N-acetylation occurred at the amino groups of both neuraminosyl and sphingosyl residues, yielding D5. |
| TextSentencer_T7 | 1311-1409 | Sentence | denotes | The structures of these derivatives were verified by 1H-n.m.r. spectroscopy and mass spectrometry. |
| T1 | 0-141 | Sentence | denotes | Synthesis and characterization of lyso-GM3 (II3Neu5Ac Lactosyl sphingosine), de-N-acetyl-GM3 (II3NeuNH2 lactosyl Cer), and related compounds. |
| T2 | 142-264 | Sentence | denotes | Various GM3 derivatives which are present in A431 cells have different effects on the activity of the EGF receptor kinase. |
| T3 | 265-515 | Sentence | denotes | In order to systematically study these effects, the following GM3 derivatives have been synthesized: de-N-acetyl-GM3 (D1), de-N-acetyl-lyso-GM3 (D2), lyso-GM3 (D3), de-N-acetyl-GM3 with N-acetylsphingosine (D4), and GM3 with N-acetylsphingosine (D3). |
| T4 | 516-685 | Sentence | denotes | A crucial step for the preparation of D1 is the use of mild alkaline conditions of hydrolysis under which the N-acetyl group of sialic acid is preferentially hydrolyzed. |
| T5 | 686-1104 | Sentence | denotes | For the preparation of D3, conditions which allowed preferential N-acetylation of the amino group of the neuraminic acid moiety were devised, i.e., D2 was incorporated in a dipalmitoyl-phosphatidylcholine (dpPC) liposome in which the sphingosine moiety was protected and the amino group of neuraminic acid was N-acetylated with acetate and a water-soluble catalyst, 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide (DEC). |
| T6 | 1105-1310 | Sentence | denotes | When an aqueous micellar solution of D2 was treated with acetic anhydride and sodium hydrogencarbonate, N-acetylation occurred at the amino groups of both neuraminosyl and sphingosyl residues, yielding D5. |
| T7 | 1311-1409 | Sentence | denotes | The structures of these derivatives were verified by 1H-n.m.r. spectroscopy and mass spectrometry. |
Glycosmos6-GlycoEpitope
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 80-92 | http://www.glycoepitope.jp/epitopes/EP0053 | denotes | N-acetyl-GM3 |
| T2 | 369-381 | http://www.glycoepitope.jp/epitopes/EP0053 | denotes | N-acetyl-GM3 |
| T3 | 433-445 | http://www.glycoepitope.jp/epitopes/EP0053 | denotes | N-acetyl-GM3 |
GlyCosmos15-Glycan
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 39-42 | Glycan | denotes | GM3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G91237TK |
| T2 | 89-92 | Glycan | denotes | GM3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G91237TK |
| T3 | 150-153 | Glycan | denotes | GM3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G91237TK |
| T4 | 327-330 | Glycan | denotes | GM3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G91237TK |
| T5 | 378-381 | Glycan | denotes | GM3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G91237TK |
| T6 | 405-408 | Glycan | denotes | GM3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G91237TK |
| T7 | 420-423 | Glycan | denotes | GM3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G91237TK |
| T8 | 442-445 | Glycan | denotes | GM3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G91237TK |
| T9 | 481-484 | Glycan | denotes | GM3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G91237TK |
Glycan-GlyCosmos
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 39-42 | Glycan | denotes | GM3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G91237TK |
| T2 | 89-92 | Glycan | denotes | GM3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G91237TK |
| T3 | 150-153 | Glycan | denotes | GM3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G91237TK |
| T4 | 327-330 | Glycan | denotes | GM3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G91237TK |
| T5 | 378-381 | Glycan | denotes | GM3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G91237TK |
| T6 | 405-408 | Glycan | denotes | GM3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G91237TK |
| T7 | 420-423 | Glycan | denotes | GM3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G91237TK |
| T8 | 442-445 | Glycan | denotes | GM3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G91237TK |
| T9 | 481-484 | Glycan | denotes | GM3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G91237TK |
GlyCosmos-GlycoEpitope
| Id | Subject | Object | Predicate | Lexical cue | glycoepitope_id |
|---|---|---|---|---|---|
| T1 | 80-92 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | N-acetyl-GM3 | http://www.glycoepitope.jp/epitopes/EP0053 |
| T2 | 369-381 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | N-acetyl-GM3 | http://www.glycoepitope.jp/epitopes/EP0053 |
| T3 | 433-445 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | N-acetyl-GM3 | http://www.glycoepitope.jp/epitopes/EP0053 |
GlyCosmos15-Sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-141 | Sentence | denotes | Synthesis and characterization of lyso-GM3 (II3Neu5Ac Lactosyl sphingosine), de-N-acetyl-GM3 (II3NeuNH2 lactosyl Cer), and related compounds. |
| T2 | 142-264 | Sentence | denotes | Various GM3 derivatives which are present in A431 cells have different effects on the activity of the EGF receptor kinase. |
| T3 | 265-515 | Sentence | denotes | In order to systematically study these effects, the following GM3 derivatives have been synthesized: de-N-acetyl-GM3 (D1), de-N-acetyl-lyso-GM3 (D2), lyso-GM3 (D3), de-N-acetyl-GM3 with N-acetylsphingosine (D4), and GM3 with N-acetylsphingosine (D3). |
| T4 | 516-685 | Sentence | denotes | A crucial step for the preparation of D1 is the use of mild alkaline conditions of hydrolysis under which the N-acetyl group of sialic acid is preferentially hydrolyzed. |
| T5 | 686-1104 | Sentence | denotes | For the preparation of D3, conditions which allowed preferential N-acetylation of the amino group of the neuraminic acid moiety were devised, i.e., D2 was incorporated in a dipalmitoyl-phosphatidylcholine (dpPC) liposome in which the sphingosine moiety was protected and the amino group of neuraminic acid was N-acetylated with acetate and a water-soluble catalyst, 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide (DEC). |
| T6 | 1105-1310 | Sentence | denotes | When an aqueous micellar solution of D2 was treated with acetic anhydride and sodium hydrogencarbonate, N-acetylation occurred at the amino groups of both neuraminosyl and sphingosyl residues, yielding D5. |
| T7 | 1311-1409 | Sentence | denotes | The structures of these derivatives were verified by 1H-n.m.r. spectroscopy and mass spectrometry. |
GlyCosmos15-GlycoEpitope
| Id | Subject | Object | Predicate | Lexical cue | glycoepitope_id |
|---|---|---|---|---|---|
| T1 | 80-92 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | N-acetyl-GM3 | http://www.glycoepitope.jp/epitopes/EP0053 |
| T2 | 369-381 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | N-acetyl-GM3 | http://www.glycoepitope.jp/epitopes/EP0053 |
| T3 | 433-445 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | N-acetyl-GM3 | http://www.glycoepitope.jp/epitopes/EP0053 |