PubMed:32023685
Annnotations
LitCovid-PAS-Enju
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antiviral therapeutics for 2019 Novel Coronavirus].\nThe recent outbreak of respiratory illness in Wuhan, China is caused by a novel coronavirus, named 2019-nCoV, which is genetically close to a bat-derived coronavirus. 2019-nCoV is categorized as beta genus coronavirus, same as the two other strains - severe acute respiratory syndrome coronavirus (SARS-CoV) and Middle East respiratory syndrome coronavirus (MERS-CoV). Antiviral drugs commonly used in clinical practice, including neuraminidase inhibitors (oseltamivir, paramivir, zanamivir, etc.), ganciclovir, acyclovir and ribavirin, are invalid for 2019-nCoV and not recommended. Drugs are possibly effective for 2019-nCoV include: remdesivir, lopinavir / ritonavir, lopinavir / ritonavir combined with interferon-β, convalescent plasma, and monoclonal antibodies. But the efficacy and safety of these drugs for 2019-nCoV pneumonia patients need to be assessed by further clinical trials."}
LitCovid-ArguminSci
{"project":"LitCovid-ArguminSci","denotations":[{"id":"T1","span":{"begin":0,"end":62},"obj":"DRI_Background"},{"id":"T2","span":{"begin":63,"end":229},"obj":"DRI_Background"},{"id":"T3","span":{"begin":230,"end":431},"obj":"DRI_Background"},{"id":"T4","span":{"begin":432,"end":559},"obj":"DRI_Background"},{"id":"T5","span":{"begin":559,"end":646},"obj":"DRI_Background"},{"id":"T6","span":{"begin":647,"end":831},"obj":"DRI_Background"},{"id":"T7","span":{"begin":832,"end":955},"obj":"DRI_Challenge"}],"text":"[Potential antiviral therapeutics for 2019 Novel Coronavirus].\nThe recent outbreak of respiratory illness in Wuhan, China is caused by a novel coronavirus, named 2019-nCoV, which is genetically close to a bat-derived coronavirus. 2019-nCoV is categorized as beta genus coronavirus, same as the two other strains - severe acute respiratory syndrome coronavirus (SARS-CoV) and Middle East respiratory syndrome coronavirus (MERS-CoV). Antiviral drugs commonly used in clinical practice, including neuraminidase inhibitors (oseltamivir, paramivir, zanamivir, etc.), ganciclovir, acyclovir and ribavirin, are invalid for 2019-nCoV and not recommended. Drugs are possibly effective for 2019-nCoV include: remdesivir, lopinavir / ritonavir, lopinavir / ritonavir combined with interferon-β, convalescent plasma, and monoclonal antibodies. But the efficacy and safety of these drugs for 2019-nCoV pneumonia patients need to be assessed by further clinical trials."}
LitCovid-OGER
{"project":"LitCovid-OGER","denotations":[{"id":"T1","span":{"begin":432,"end":447},"obj":"CHEBI:36044"},{"id":"T2","span":{"begin":508,"end":518},"obj":"CHEBI:35222"},{"id":"T3","span":{"begin":520,"end":531},"obj":"CHEBI:7798"},{"id":"T4","span":{"begin":544,"end":553},"obj":"CHEBI:50663"},{"id":"T5","span":{"begin":562,"end":573},"obj":"CHEBI:465284"},{"id":"T6","span":{"begin":575,"end":584},"obj":"CHEBI:2453"},{"id":"T7","span":{"begin":589,"end":598},"obj":"CHEBI:63580"},{"id":"T8","span":{"begin":711,"end":720},"obj":"CHEBI:31781"},{"id":"T9","span":{"begin":723,"end":732},"obj":"CHEBI:45409"},{"id":"T10","span":{"begin":734,"end":743},"obj":"CHEBI:31781"},{"id":"T11","span":{"begin":746,"end":755},"obj":"CHEBI:45409"},{"id":"T1","span":{"begin":820,"end":830},"obj":"GO:0042571"},{"id":"T1","span":{"begin":361,"end":365},"obj":"PR:000014459"},{"id":"T2","span":{"begin":770,"end":782},"obj":"PR:000024939"},{"id":"T1","span":{"begin":600,"end":603},"obj":"SO:0001853"},{"id":"T2","span":{"begin":653,"end":656},"obj":"SO:0001853"},{"id":"T3","span":{"begin":916,"end":918},"obj":"SO:0000999"}],"namespaces":[{"prefix":"PR","uri":"http://purl.obolibrary.org/obo/PR_"},{"prefix":"UBERON","uri":"http://purl.obolibrary.org/obo/UBERON_"}],"text":"[Potential antiviral therapeutics for 2019 Novel Coronavirus].\nThe recent outbreak of respiratory illness in Wuhan, China is caused by a novel coronavirus, named 2019-nCoV, which is genetically close to a bat-derived coronavirus. 2019-nCoV is categorized as beta genus coronavirus, same as the two other strains - severe acute respiratory syndrome coronavirus (SARS-CoV) and Middle East respiratory syndrome coronavirus (MERS-CoV). Antiviral drugs commonly used in clinical practice, including neuraminidase inhibitors (oseltamivir, paramivir, zanamivir, etc.), ganciclovir, acyclovir and ribavirin, are invalid for 2019-nCoV and not recommended. Drugs are possibly effective for 2019-nCoV include: remdesivir, lopinavir / ritonavir, lopinavir / ritonavir combined with interferon-β, convalescent plasma, and monoclonal antibodies. But the efficacy and safety of these drugs for 2019-nCoV pneumonia patients need to be assessed by further clinical trials."}
LitCovid-PubTatorCentral
{"project":"LitCovid-PubTatorCentral","denotations":[{"id":"T1","span":{"begin":86,"end":105},"obj":"Disease:MESH:D012131"},{"id":"T2","span":{"begin":314,"end":359},"obj":"Species:227859"},{"id":"T3","span":{"begin":361,"end":369},"obj":"Species:227859"},{"id":"T4","span":{"begin":375,"end":419},"obj":"Disease:MESH:D018352"},{"id":"T5","span":{"begin":421,"end":429},"obj":"Disease:MESH:D018352"},{"id":"T6","span":{"begin":520,"end":531},"obj":"Chemical:MESH:D053139"},{"id":"T7","span":{"begin":533,"end":542},"obj":"Chemical:"},{"id":"T8","span":{"begin":544,"end":553},"obj":"Chemical:MESH:D053243"},{"id":"T9","span":{"begin":562,"end":573},"obj":"Chemical:MESH:D015774"},{"id":"T10","span":{"begin":575,"end":584},"obj":"Chemical:MESH:D000212"},{"id":"T11","span":{"begin":589,"end":598},"obj":"Chemical:MESH:D012254"},{"id":"T12","span":{"begin":711,"end":720},"obj":"Chemical:MESH:D061466"},{"id":"T13","span":{"begin":723,"end":732},"obj":"Chemical:MESH:D019438"},{"id":"T14","span":{"begin":734,"end":743},"obj":"Chemical:MESH:D061466"},{"id":"T15","span":{"begin":746,"end":755},"obj":"Chemical:MESH:D019438"},{"id":"T16","span":{"begin":889,"end":898},"obj":"Disease:MESH:D011014"},{"id":"T17","span":{"begin":899,"end":907},"obj":"Species:9606"}],"text":"[Potential antiviral therapeutics for 2019 Novel Coronavirus].\nThe recent outbreak of respiratory illness in Wuhan, China is caused by a novel coronavirus, named 2019-nCoV, which is genetically close to a bat-derived coronavirus. 2019-nCoV is categorized as beta genus coronavirus, same as the two other strains - severe acute respiratory syndrome coronavirus (SARS-CoV) and Middle East respiratory syndrome coronavirus (MERS-CoV). Antiviral drugs commonly used in clinical practice, including neuraminidase inhibitors (oseltamivir, paramivir, zanamivir, etc.), ganciclovir, acyclovir and ribavirin, are invalid for 2019-nCoV and not recommended. Drugs are possibly effective for 2019-nCoV include: remdesivir, lopinavir / ritonavir, lopinavir / ritonavir combined with interferon-β, convalescent plasma, and monoclonal antibodies. But the efficacy and safety of these drugs for 2019-nCoV pneumonia patients need to be assessed by further clinical trials."}
LitCovid-sentences-v1
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LitCovid-TimeML
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LitCovid-PD-MONDO-v1
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LitCovid-PD-HP-v1
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LitCovid-PD-FMA-UBERON-v1
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LitCovid-PD-FMA-UBERON
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LitCovid-PD-MONDO
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LitCovid-PD-CLO
{"project":"LitCovid-PD-CLO","denotations":[{"id":"T1","span":{"begin":135,"end":136},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T2","span":{"begin":203,"end":204},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T3","span":{"begin":205,"end":208},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_9397"},{"id":"T4","span":{"begin":797,"end":803},"obj":"http://purl.obolibrary.org/obo/UBERON_0001969"}],"text":"[Potential antiviral therapeutics for 2019 Novel Coronavirus].\nThe recent outbreak of respiratory illness in Wuhan, China is caused by a novel coronavirus, named 2019-nCoV, which is genetically close to a bat-derived coronavirus. 2019-nCoV is categorized as beta genus coronavirus, same as the two other strains - severe acute respiratory syndrome coronavirus (SARS-CoV) and Middle East respiratory syndrome coronavirus (MERS-CoV). Antiviral drugs commonly used in clinical practice, including neuraminidase inhibitors (oseltamivir, paramivir, zanamivir, etc.), ganciclovir, acyclovir and ribavirin, are invalid for 2019-nCoV and not recommended. Drugs are possibly effective for 2019-nCoV include: remdesivir, lopinavir / ritonavir, lopinavir / ritonavir combined with interferon-β, convalescent plasma, and monoclonal antibodies. But the efficacy and safety of these drugs for 2019-nCoV pneumonia patients need to be assessed by further clinical trials."}
LitCovid-PD-CHEBI
{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T1","span":{"begin":11,"end":20},"obj":"Chemical"},{"id":"T2","span":{"begin":258,"end":262},"obj":"Chemical"},{"id":"T3","span":{"begin":442,"end":447},"obj":"Chemical"},{"id":"T4","span":{"begin":494,"end":518},"obj":"Chemical"},{"id":"T5","span":{"begin":508,"end":518},"obj":"Chemical"},{"id":"T6","span":{"begin":520,"end":531},"obj":"Chemical"},{"id":"T7","span":{"begin":544,"end":553},"obj":"Chemical"},{"id":"T8","span":{"begin":562,"end":573},"obj":"Chemical"},{"id":"T9","span":{"begin":575,"end":584},"obj":"Chemical"},{"id":"T10","span":{"begin":589,"end":598},"obj":"Chemical"},{"id":"T11","span":{"begin":699,"end":709},"obj":"Chemical"},{"id":"T12","span":{"begin":711,"end":720},"obj":"Chemical"},{"id":"T13","span":{"begin":723,"end":732},"obj":"Chemical"},{"id":"T14","span":{"begin":734,"end":743},"obj":"Chemical"},{"id":"T15","span":{"begin":746,"end":755},"obj":"Chemical"},{"id":"T16","span":{"begin":770,"end":780},"obj":"Chemical"},{"id":"T17","span":{"begin":869,"end":874},"obj":"Chemical"}],"attributes":[{"id":"A1","pred":"chebi_id","subj":"T1","obj":"http://purl.obolibrary.org/obo/CHEBI_22587"},{"id":"A2","pred":"chebi_id","subj":"T2","obj":"http://purl.obolibrary.org/obo/CHEBI_10545"},{"id":"A3","pred":"chebi_id","subj":"T3","obj":"http://purl.obolibrary.org/obo/CHEBI_23888"},{"id":"A4","pred":"chebi_id","subj":"T4","obj":"http://purl.obolibrary.org/obo/CHEBI_52425"},{"id":"A5","pred":"chebi_id","subj":"T5","obj":"http://purl.obolibrary.org/obo/CHEBI_35222"},{"id":"A6","pred":"chebi_id","subj":"T6","obj":"http://purl.obolibrary.org/obo/CHEBI_7798"},{"id":"A7","pred":"chebi_id","subj":"T7","obj":"http://purl.obolibrary.org/obo/CHEBI_50663"},{"id":"A8","pred":"chebi_id","subj":"T8","obj":"http://purl.obolibrary.org/obo/CHEBI_465284"},{"id":"A9","pred":"chebi_id","subj":"T9","obj":"http://purl.obolibrary.org/obo/CHEBI_2453"},{"id":"A10","pred":"chebi_id","subj":"T10","obj":"http://purl.obolibrary.org/obo/CHEBI_63580"},{"id":"A11","pred":"chebi_id","subj":"T11","obj":"http://purl.obolibrary.org/obo/CHEBI_145994"},{"id":"A12","pred":"chebi_id","subj":"T12","obj":"http://purl.obolibrary.org/obo/CHEBI_31781"},{"id":"A13","pred":"chebi_id","subj":"T13","obj":"http://purl.obolibrary.org/obo/CHEBI_45409"},{"id":"A14","pred":"chebi_id","subj":"T14","obj":"http://purl.obolibrary.org/obo/CHEBI_31781"},{"id":"A15","pred":"chebi_id","subj":"T15","obj":"http://purl.obolibrary.org/obo/CHEBI_45409"},{"id":"A16","pred":"chebi_id","subj":"T16","obj":"http://purl.obolibrary.org/obo/CHEBI_52999"},{"id":"A17","pred":"chebi_id","subj":"T17","obj":"http://purl.obolibrary.org/obo/CHEBI_23888"}],"text":"[Potential antiviral therapeutics for 2019 Novel Coronavirus].\nThe recent outbreak of respiratory illness in Wuhan, China is caused by a novel coronavirus, named 2019-nCoV, which is genetically close to a bat-derived coronavirus. 2019-nCoV is categorized as beta genus coronavirus, same as the two other strains - severe acute respiratory syndrome coronavirus (SARS-CoV) and Middle East respiratory syndrome coronavirus (MERS-CoV). Antiviral drugs commonly used in clinical practice, including neuraminidase inhibitors (oseltamivir, paramivir, zanamivir, etc.), ganciclovir, acyclovir and ribavirin, are invalid for 2019-nCoV and not recommended. Drugs are possibly effective for 2019-nCoV include: remdesivir, lopinavir / ritonavir, lopinavir / ritonavir combined with interferon-β, convalescent plasma, and monoclonal antibodies. But the efficacy and safety of these drugs for 2019-nCoV pneumonia patients need to be assessed by further clinical trials."}
LitCovid-PubTator
{"project":"LitCovid-PubTator","denotations":[{"id":"1","span":{"begin":38,"end":60},"obj":"Species"},{"id":"25","span":{"begin":86,"end":105},"obj":"Disease"},{"id":"26","span":{"begin":137,"end":154},"obj":"Species"},{"id":"27","span":{"begin":162,"end":171},"obj":"Species"},{"id":"28","span":{"begin":217,"end":239},"obj":"Species"},{"id":"29","span":{"begin":269,"end":280},"obj":"Species"},{"id":"30","span":{"begin":314,"end":359},"obj":"Species"},{"id":"31","span":{"begin":361,"end":369},"obj":"Species"},{"id":"32","span":{"begin":408,"end":419},"obj":"Species"},{"id":"33","span":{"begin":494,"end":507},"obj":"Gene"},{"id":"34","span":{"begin":520,"end":531},"obj":"Chemical"},{"id":"35","span":{"begin":533,"end":542},"obj":"Chemical"},{"id":"36","span":{"begin":544,"end":553},"obj":"Chemical"},{"id":"37","span":{"begin":562,"end":573},"obj":"Chemical"},{"id":"38","span":{"begin":575,"end":584},"obj":"Chemical"},{"id":"39","span":{"begin":589,"end":598},"obj":"Chemical"},{"id":"40","span":{"begin":616,"end":625},"obj":"Species"},{"id":"41","span":{"begin":680,"end":689},"obj":"Species"},{"id":"42","span":{"begin":699,"end":709},"obj":"Chemical"},{"id":"43","span":{"begin":711,"end":732},"obj":"Chemical"},{"id":"44","span":{"begin":734,"end":755},"obj":"Chemical"},{"id":"45","span":{"begin":770,"end":782},"obj":"Gene"},{"id":"46","span":{"begin":879,"end":898},"obj":"Disease"},{"id":"47","span":{"begin":899,"end":907},"obj":"Species"}],"attributes":[{"id":"A1","pred":"tao:has_database_id","subj":"1","obj":"Tax:2697049"},{"id":"A25","pred":"tao:has_database_id","subj":"25","obj":"MESH:D012140"},{"id":"A26","pred":"tao:has_database_id","subj":"26","obj":"Tax:2697049"},{"id":"A27","pred":"tao:has_database_id","subj":"27","obj":"Tax:2697049"},{"id":"A28","pred":"tao:has_database_id","subj":"28","obj":"Tax:2697049"},{"id":"A29","pred":"tao:has_database_id","subj":"29","obj":"Tax:11118"},{"id":"A30","pred":"tao:has_database_id","subj":"30","obj":"Tax:694009"},{"id":"A31","pred":"tao:has_database_id","subj":"31","obj":"Tax:694009"},{"id":"A32","pred":"tao:has_database_id","subj":"32","obj":"Tax:11118"},{"id":"A33","pred":"tao:has_database_id","subj":"33","obj":"Gene:4758"},{"id":"A34","pred":"tao:has_database_id","subj":"34","obj":"MESH:D053139"},{"id":"A36","pred":"tao:has_database_id","subj":"36","obj":"MESH:D053243"},{"id":"A37","pred":"tao:has_database_id","subj":"37","obj":"MESH:D015774"},{"id":"A38","pred":"tao:has_database_id","subj":"38","obj":"MESH:D000212"},{"id":"A39","pred":"tao:has_database_id","subj":"39","obj":"MESH:D012254"},{"id":"A40","pred":"tao:has_database_id","subj":"40","obj":"Tax:2697049"},{"id":"A41","pred":"tao:has_database_id","subj":"41","obj":"Tax:2697049"},{"id":"A42","pred":"tao:has_database_id","subj":"42","obj":"MESH:C000606551"},{"id":"A43","pred":"tao:has_database_id","subj":"43","obj":"MESH:C558899"},{"id":"A44","pred":"tao:has_database_id","subj":"44","obj":"MESH:C558899"},{"id":"A45","pred":"tao:has_database_id","subj":"45","obj":"Gene:3456"},{"id":"A46","pred":"tao:has_database_id","subj":"46","obj":"MESH:C000657245"},{"id":"A47","pred":"tao:has_database_id","subj":"47","obj":"Tax:9606"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"[Potential antiviral therapeutics for 2019 Novel Coronavirus].\nThe recent outbreak of respiratory illness in Wuhan, China is caused by a novel coronavirus, named 2019-nCoV, which is genetically close to a bat-derived coronavirus. 2019-nCoV is categorized as beta genus coronavirus, same as the two other strains - severe acute respiratory syndrome coronavirus (SARS-CoV) and Middle East respiratory syndrome coronavirus (MERS-CoV). Antiviral drugs commonly used in clinical practice, including neuraminidase inhibitors (oseltamivir, paramivir, zanamivir, etc.), ganciclovir, acyclovir and ribavirin, are invalid for 2019-nCoV and not recommended. Drugs are possibly effective for 2019-nCoV include: remdesivir, lopinavir / ritonavir, lopinavir / ritonavir combined with interferon-β, convalescent plasma, and monoclonal antibodies. But the efficacy and safety of these drugs for 2019-nCoV pneumonia patients need to be assessed by further clinical trials."}
LitCovid-PD-HP
{"project":"LitCovid-PD-HP","denotations":[{"id":"T1","span":{"begin":86,"end":105},"obj":"Phenotype"},{"id":"T2","span":{"begin":889,"end":898},"obj":"Phenotype"}],"attributes":[{"id":"A1","pred":"hp_id","subj":"T1","obj":"http://purl.obolibrary.org/obo/HP_0002086"},{"id":"A2","pred":"hp_id","subj":"T2","obj":"http://purl.obolibrary.org/obo/HP_0002090"}],"text":"[Potential antiviral therapeutics for 2019 Novel Coronavirus].\nThe recent outbreak of respiratory illness in Wuhan, China is caused by a novel coronavirus, named 2019-nCoV, which is genetically close to a bat-derived coronavirus. 2019-nCoV is categorized as beta genus coronavirus, same as the two other strains - severe acute respiratory syndrome coronavirus (SARS-CoV) and Middle East respiratory syndrome coronavirus (MERS-CoV). Antiviral drugs commonly used in clinical practice, including neuraminidase inhibitors (oseltamivir, paramivir, zanamivir, etc.), ganciclovir, acyclovir and ribavirin, are invalid for 2019-nCoV and not recommended. Drugs are possibly effective for 2019-nCoV include: remdesivir, lopinavir / ritonavir, lopinavir / ritonavir combined with interferon-β, convalescent plasma, and monoclonal antibodies. But the efficacy and safety of these drugs for 2019-nCoV pneumonia patients need to be assessed by further clinical trials."}
LitCovid_AGAC_only
{"project":"LitCovid_AGAC_only","denotations":[{"id":"p107s4","span":{"begin":86,"end":105},"obj":"Disease"},{"id":"p107s11","span":{"begin":125,"end":134},"obj":"Reg"}],"text":"[Potential antiviral therapeutics for 2019 Novel Coronavirus].\nThe recent outbreak of respiratory illness in Wuhan, China is caused by a novel coronavirus, named 2019-nCoV, which is genetically close to a bat-derived coronavirus. 2019-nCoV is categorized as beta genus coronavirus, same as the two other strains - severe acute respiratory syndrome coronavirus (SARS-CoV) and Middle East respiratory syndrome coronavirus (MERS-CoV). Antiviral drugs commonly used in clinical practice, including neuraminidase inhibitors (oseltamivir, paramivir, zanamivir, etc.), ganciclovir, acyclovir and ribavirin, are invalid for 2019-nCoV and not recommended. Drugs are possibly effective for 2019-nCoV include: remdesivir, lopinavir / ritonavir, lopinavir / ritonavir combined with interferon-β, convalescent plasma, and monoclonal antibodies. But the efficacy and safety of these drugs for 2019-nCoV pneumonia patients need to be assessed by further clinical trials."}
LitCovid-sentences
{"project":"LitCovid-sentences","denotations":[{"id":"T1","span":{"begin":0,"end":62},"obj":"Sentence"},{"id":"T2","span":{"begin":63,"end":229},"obj":"Sentence"},{"id":"T3","span":{"begin":230,"end":431},"obj":"Sentence"},{"id":"T4","span":{"begin":432,"end":646},"obj":"Sentence"},{"id":"T5","span":{"begin":647,"end":831},"obj":"Sentence"},{"id":"T6","span":{"begin":832,"end":955},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"[Potential antiviral therapeutics for 2019 Novel Coronavirus].\nThe recent outbreak of respiratory illness in Wuhan, China is caused by a novel coronavirus, named 2019-nCoV, which is genetically close to a bat-derived coronavirus. 2019-nCoV is categorized as beta genus coronavirus, same as the two other strains - severe acute respiratory syndrome coronavirus (SARS-CoV) and Middle East respiratory syndrome coronavirus (MERS-CoV). Antiviral drugs commonly used in clinical practice, including neuraminidase inhibitors (oseltamivir, paramivir, zanamivir, etc.), ganciclovir, acyclovir and ribavirin, are invalid for 2019-nCoV and not recommended. Drugs are possibly effective for 2019-nCoV include: remdesivir, lopinavir / ritonavir, lopinavir / ritonavir combined with interferon-β, convalescent plasma, and monoclonal antibodies. But the efficacy and safety of these drugs for 2019-nCoV pneumonia patients need to be assessed by further clinical trials."}