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PubMed:318684 JSONTXT

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sentences

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-149 Sentence denotes Hereditary deficiency of the third component of complement in a child with fever, skin rash, and arthralgias: response to transfusion of whole blood.
TextSentencer_T2 150-323 Sentence denotes A previously well 34-month-old male presenting with fever, skin rash, and arthralgias was found to lack C3 by immunochemical (undetectable) and hemolytic (1% normal) assays.
TextSentencer_T3 324-366 Sentence denotes No infectious agent could be demonstrated.
TextSentencer_T4 367-389 Sentence denotes Protein levels of Clq.
TextSentencer_T5 390-606 Sentence denotes C4, C5, properdin, and C3b-INA and hemolytic activities of complement components C1 to C9 except C3 were normal or elevated; total hemolytic complement activity was 13% of normal and was reconstituted by purified C3.
TextSentencer_T6 607-729 Sentence denotes Properdin factor B was 702 (normal 175 to 275) mug/ml, and was not cleaver upon addition of zymosan or cobra venom factor.
TextSentencer_T7 730-1016 Sentence denotes The serum had normal immune adherence activity, but was deficient in ability to opsonize Candida albicans for uptake and Escherichia coli for killing by neurophils, generate neutrophil chemotactic factors and inhibit the growth of E. coli; these activities were restored by purified C3.
TextSentencer_T8 1017-1381 Sentence denotes A transfusion of 320 ml 1-hour-old normal whole blood on the fifty-second day resulted in transitory elevation of the C3 level to 25 mg/dl with a fall-off (approximately 2 1/2% per hour) to undetectable levels by 69 hours; it was followed by disappearance of the skin rash and arthralgias and return to normal of the previously elevated temperature and CRP levels.
TextSentencer_T9 1382-1644 Sentence denotes C3 levels in family members (seven of 24 half-normal), lack of anti-C3 activity, normal C3b-INA levels and a normal rate of catabolism of transfused C3 indicated that the deficiency was inherited with autosomal codominance and involved decreased synthesis of C3.
TextSentencer_T10 1645-1852 Sentence denotes Thus, this child is a unique individual with inherited C3 deficiency presenting with absence of repeated infections, whose symptoms of fever, skin rash, and arthralgia were abated by whole blood transfusion.
T1 0-149 Sentence denotes Hereditary deficiency of the third component of complement in a child with fever, skin rash, and arthralgias: response to transfusion of whole blood.
T2 150-323 Sentence denotes A previously well 34-month-old male presenting with fever, skin rash, and arthralgias was found to lack C3 by immunochemical (undetectable) and hemolytic (1% normal) assays.
T3 324-366 Sentence denotes No infectious agent could be demonstrated.
T4 367-389 Sentence denotes Protein levels of Clq.
T5 390-606 Sentence denotes C4, C5, properdin, and C3b-INA and hemolytic activities of complement components C1 to C9 except C3 were normal or elevated; total hemolytic complement activity was 13% of normal and was reconstituted by purified C3.
T6 607-729 Sentence denotes Properdin factor B was 702 (normal 175 to 275) mug/ml, and was not cleaver upon addition of zymosan or cobra venom factor.
T7 730-1016 Sentence denotes The serum had normal immune adherence activity, but was deficient in ability to opsonize Candida albicans for uptake and Escherichia coli for killing by neurophils, generate neutrophil chemotactic factors and inhibit the growth of E. coli; these activities were restored by purified C3.
T8 1017-1381 Sentence denotes A transfusion of 320 ml 1-hour-old normal whole blood on the fifty-second day resulted in transitory elevation of the C3 level to 25 mg/dl with a fall-off (approximately 2 1/2% per hour) to undetectable levels by 69 hours; it was followed by disappearance of the skin rash and arthralgias and return to normal of the previously elevated temperature and CRP levels.
T9 1382-1644 Sentence denotes C3 levels in family members (seven of 24 half-normal), lack of anti-C3 activity, normal C3b-INA levels and a normal rate of catabolism of transfused C3 indicated that the deficiency was inherited with autosomal codominance and involved decreased synthesis of C3.
T10 1645-1852 Sentence denotes Thus, this child is a unique individual with inherited C3 deficiency presenting with absence of repeated infections, whose symptoms of fever, skin rash, and arthralgia were abated by whole blood transfusion.

performance-test

Id Subject Object Predicate Lexical cue
PD-UBERON-AE-B_T1 143-148 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
PD-UBERON-AE-B_T2 1065-1070 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
PD-UBERON-AE-B_T3 1834-1839 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
PD-UBERON-AE-B_T4 734-739 http://purl.obolibrary.org/obo/UBERON_0001977 denotes serum
PD-UBERON-AE-B_T5 716-721 http://purl.obolibrary.org/obo/UBERON_0007113 denotes venom

UBERON-AE

Id Subject Object Predicate Lexical cue
PD-UBERON-AE-B_T1 143-148 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
PD-UBERON-AE-B_T2 1065-1070 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
PD-UBERON-AE-B_T3 1834-1839 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
PD-UBERON-AE-B_T4 716-721 http://purl.obolibrary.org/obo/UBERON_0007113 denotes venom
PD-UBERON-AE-B_T5 734-739 http://purl.obolibrary.org/obo/UBERON_0001977 denotes serum

PubCasesHPO

Id Subject Object Predicate Lexical cue
AB1 202-207 HP:0001945 denotes fever
AB2 209-218 HP:0000988 denotes skin rash
AB3 224-235 HP:0002829 denotes arthralgias
TI1 82-91 HP:0000988 denotes skin rash
TI2 97-108 HP:0002829 denotes arthralgias
AB4 1163-1167 HP:0002527 denotes fall
AB5 1280-1289 HP:0000988 denotes skin rash
AB6 1294-1305 HP:0002829 denotes arthralgias
AB7 1780-1785 HP:0001945 denotes fever
AB8 1787-1796 HP:0000988 denotes skin rash
AB9 1802-1812 HP:0002829 denotes arthralgia

PubCasesORDO

Id Subject Object Predicate Lexical cue
AB1 1700-1713 ORDO:280133 denotes C3 deficiency

NCBIDiseaseCorpus

Id Subject Object Predicate Lexical cue
T1 0-58 SpecificDisease:OMIM:613779 denotes Hereditary deficiency of the third component of complement
T2 75-80 DiseaseClass:D005334 denotes fever
T3 82-91 DiseaseClass:D005076 denotes skin rash
T4 97-108 DiseaseClass:D018771 denotes arthralgias
T5 202-207 DiseaseClass:D005334 denotes fever
T6 209-218 DiseaseClass:D005076 denotes skin rash
T7 224-235 DiseaseClass:D018771 denotes arthralgias
T8 1280-1289 DiseaseClass:D005076 denotes skin rash
T9 1294-1305 DiseaseClass:D018771 denotes arthralgias
T10 1618-1643 DiseaseClass:OMIM:613779 denotes decreased synthesis of C3
T11 1690-1713 SpecificDisease:OMIM:613779 denotes inherited C3 deficiency
T12 1780-1785 DiseaseClass:D005334 denotes fever
T13 1787-1796 DiseaseClass:D005076 denotes skin rash
T14 1802-1812 DiseaseClass:D018771 denotes arthralgia

NCBI-Disease-Train

Id Subject Object Predicate Lexical cue database_id
T2388 0-58 SpecificDisease denotes Hereditary deficiency of the third component of complement OMIM:613779
T2389 75-80 DiseaseClass denotes fever D005334
T2390 82-91 DiseaseClass denotes skin rash D005076
T2391 97-108 DiseaseClass denotes arthralgias D018771
T2392 202-207 DiseaseClass denotes fever D005334
T2393 209-218 DiseaseClass denotes skin rash D005076
T2394 224-235 DiseaseClass denotes arthralgias D018771
T2395 1280-1289 DiseaseClass denotes skin rash D005076
T2396 1294-1305 DiseaseClass denotes arthralgias D018771
T2397 1618-1643 DiseaseClass denotes decreased synthesis of C3 OMIM:613779
T2398 1690-1713 SpecificDisease denotes inherited C3 deficiency OMIM:613779
T2399 1780-1785 DiseaseClass denotes fever D005334
T2400 1787-1796 DiseaseClass denotes skin rash D005076
T2401 1802-1812 DiseaseClass denotes arthralgia D018771

NCBI-Disease-Corpus-All

Id Subject Object Predicate Lexical cue database_id
T2388 0-58 SpecificDisease denotes Hereditary deficiency of the third component of complement OMIM:613779
T2389 75-80 DiseaseClass denotes fever D005334
T2390 82-91 DiseaseClass denotes skin rash D005076
T2391 97-108 DiseaseClass denotes arthralgias D018771
T2392 202-207 DiseaseClass denotes fever D005334
T2393 209-218 DiseaseClass denotes skin rash D005076
T2394 224-235 DiseaseClass denotes arthralgias D018771
T2395 1280-1289 DiseaseClass denotes skin rash D005076
T2396 1294-1305 DiseaseClass denotes arthralgias D018771
T2397 1618-1643 DiseaseClass denotes decreased synthesis of C3 OMIM:613779
T2398 1690-1713 SpecificDisease denotes inherited C3 deficiency OMIM:613779
T2399 1780-1785 DiseaseClass denotes fever D005334
T2400 1787-1796 DiseaseClass denotes skin rash D005076
T2401 1802-1812 DiseaseClass denotes arthralgia D018771

NCBI-Disease-Corpus-2stage-All

Id Subject Object Predicate Lexical cue
T1 75-80 DiseaseClass denotes fever
T2 82-91 DiseaseClass denotes skin rash
T3 97-108 DiseaseClass denotes arthralgias
T4 202-207 DiseaseClass denotes fever
T5 209-218 DiseaseClass denotes skin rash
T6 224-235 DiseaseClass denotes arthralgias
T7 1280-1289 DiseaseClass denotes skin rash
T8 1294-1305 DiseaseClass denotes arthralgias
T9 1780-1785 DiseaseClass denotes fever
T10 1787-1796 DiseaseClass denotes skin rash
T11 1802-1812 DiseaseClass denotes arthralgia

NCBI-Disease-Corpus-rezarta-All

Id Subject Object Predicate Lexical cue
T1 75-80 DiseaseClass denotes fever
T2 82-91 DiseaseClass denotes skin rash
T3 97-108 DiseaseClass denotes arthralgias
T4 202-207 DiseaseClass denotes fever
T5 209-218 DiseaseClass denotes skin rash
T6 224-235 DiseaseClass denotes arthralgias
T7 1280-1289 DiseaseClass denotes skin rash
T8 1294-1305 DiseaseClass denotes arthralgias
T9 1700-1713 SpecificDisease denotes C3 deficiency
T10 1780-1785 DiseaseClass denotes fever
T11 1787-1796 DiseaseClass denotes skin rash
T12 1802-1812 DiseaseClass denotes arthralgia

NCBI-Disease-Corpus-4oGuideline-All

Id Subject Object Predicate Lexical cue
T1 11-58 SpecificDisease denotes deficiency of the third component of complement
T2 202-207 Modifier denotes fever
T3 209-218 Modifier denotes skin rash
T4 224-235 Modifier denotes arthralgias
T5 254-256 SpecificDisease denotes C3
T6 1280-1289 Modifier denotes skin rash
T7 1294-1305 Modifier denotes arthralgias
T8 1700-1713 SpecificDisease denotes C3 deficiency
T9 1780-1785 Modifier denotes fever
T10 1787-1796 Modifier denotes skin rash
T11 1802-1812 Modifier denotes arthralgia

NCBI-Disease-Corpus-Simple-All

Id Subject Object Predicate Lexical cue
T1 0-58 SpecificDisease denotes Hereditary deficiency of the third component of complement
T2 75-108 CompositeMention denotes fever, skin rash, and arthralgias
T3 202-235 CompositeMention denotes fever, skin rash, and arthralgias
T4 1280-1305 CompositeMention denotes skin rash and arthralgias
T5 1690-1713 SpecificDisease denotes inherited C3 deficiency
T6 1780-1812 CompositeMention denotes fever, skin rash, and arthralgia