PubMed:31690627
Annnotations
GoldHamster
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T4 | 0-7 | 114202 | denotes | Lactate |
| T1 | 0-7 | D019344 | denotes | Lactate |
| T2 | 0-7 | CHEBI:16651 | denotes | Lactate |
| T3 | 0-7 | D019344 | denotes | Lactate |
| T5 | 0-7 | CHEBI:24996 | denotes | Lactate |
| T6 | 47-56 | CL:0000136 | denotes | adipocyte |
| T7 | 57-67 | GO:0008152 | denotes | metabolism |
| T8 | 77-83 | UBERON:0000479 | denotes | tissue |
| T9 | 101-111 | UBERON:0000468 | denotes | whole-body |
| T10 | 101-111 | UBERON:0013702 | denotes | whole-body |
| T13 | 112-119 | 4850 | denotes | glucose |
| T11 | 112-119 | D005947 | denotes | glucose |
| T12 | 112-119 | D005947 | denotes | glucose |
| T14 | 112-119 | CHEBI:42758 | denotes | glucose |
| T15 | 112-119 | CHEBI:4167 | denotes | glucose |
| T16 | 112-119 | CHEBI:17234 | denotes | glucose |
| T17 | 112-131 | GO:0042593 | denotes | glucose homeostasis |
| T19 | 156-161 | CHEBI:18059 | denotes | lipid |
| T20 | 156-169 | GO:0019915 | denotes | lipid storage |
| T25 | 208-215 | 114202 | denotes | lactate |
| T22 | 208-215 | D019344 | denotes | lactate |
| T23 | 208-215 | CHEBI:16651 | denotes | lactate |
| T24 | 208-215 | D019344 | denotes | lactate |
| T26 | 208-215 | CHEBI:24996 | denotes | lactate |
| T27 | 305-312 | UBERON:0001013 | denotes | adipose |
| T28 | 317-327 | UBERON:0000468 | denotes | whole-body |
| T29 | 317-327 | UBERON:0013702 | denotes | whole-body |
| T32 | 328-335 | 4850 | denotes | glucose |
| T30 | 328-335 | D005947 | denotes | glucose |
| T31 | 328-335 | D005947 | denotes | glucose |
| T33 | 328-335 | CHEBI:42758 | denotes | glucose |
| T34 | 328-335 | CHEBI:4167 | denotes | glucose |
| T35 | 328-335 | CHEBI:17234 | denotes | glucose |
| T39 | 452-459 | 114202 | denotes | lactate |
| T36 | 452-459 | D019344 | denotes | lactate |
| T37 | 452-459 | CHEBI:16651 | denotes | lactate |
| T38 | 452-459 | D019344 | denotes | lactate |
| T40 | 452-459 | CHEBI:24996 | denotes | lactate |
| T41 | 517-524 | P51463 | denotes | Insulin |
| T42 | 517-524 | Q91XI3 | denotes | Insulin |
| T43 | 517-524 | P01308 | denotes | Insulin |
| T44 | 517-524 | P01340 | denotes | Insulin |
| T45 | 517-524 | P07453 | denotes | Insulin |
| T46 | 517-524 | P68988 | denotes | Insulin |
| T47 | 517-524 | P21563 | denotes | Insulin |
| T48 | 517-524 | P68245 | denotes | Insulin |
| T49 | 517-524 | P68990 | denotes | Insulin |
| T51 | 517-524 | P09476 | denotes | Insulin |
| T52 | 517-524 | P69047 | denotes | Insulin |
| T53 | 517-524 | Q8HXV2 | denotes | Insulin |
| T54 | 517-524 | P12705 | denotes | Insulin |
| T55 | 517-524 | P68987 | denotes | Insulin |
| T57 | 517-524 | Q9NDE7 | denotes | Insulin |
| T58 | 517-524 | P13190 | denotes | Insulin |
| T59 | 517-524 | P01321 | denotes | Insulin |
| T60 | 517-524 | C0HJT9 | denotes | Insulin |
| T61 | 517-524 | P81423 | denotes | Insulin |
| T62 | 517-524 | P01327 | denotes | Insulin |
| T63 | 517-524 | P41522 | denotes | Insulin |
| T64 | 517-524 | C0HJI1 | denotes | Insulin |
| T65 | 517-524 | P01336 | denotes | Insulin |
| T66 | 517-524 | P67974 | denotes | Insulin |
| T67 | 517-524 | P69046 | denotes | Insulin |
| T68 | 517-524 | P12704 | denotes | Insulin |
| T69 | 517-524 | P42633 | denotes | Insulin |
| T70 | 517-524 | P67968 | denotes | Insulin |
| T71 | 517-524 | P01334 | denotes | Insulin |
| T72 | 517-524 | P67973 | denotes | Insulin |
| T73 | 517-524 | P01328 | denotes | Insulin |
| T74 | 517-524 | P81881 | denotes | Insulin |
| T75 | 517-524 | P01330 | denotes | Insulin |
| T76 | 517-524 | Q9W7R2 | denotes | Insulin |
| T77 | 517-524 | P09477 | denotes | Insulin |
| T78 | 517-524 | P01311 | denotes | Insulin |
| T79 | 517-524 | P01315 | denotes | Insulin |
| T80 | 517-524 | P06306 | denotes | Insulin |
| T81 | 517-524 | P01319 | denotes | Insulin |
| T82 | 517-524 | Q6YK33 | denotes | Insulin |
| T83 | 517-524 | P67971 | denotes | Insulin |
| T84 | 517-524 | Q62587 | denotes | Insulin |
| T85 | 517-524 | P68991 | denotes | Insulin |
| T86 | 517-524 | P12708 | denotes | Insulin |
| T87 | 517-524 | P04667 | denotes | Insulin |
| T89 | 517-524 | P68989 | denotes | Insulin |
| T90 | 517-524 | P01333 | denotes | Insulin |
| T91 | 517-524 | PR:000009054 | denotes | Insulin |
| T92 | 517-524 | P30410 | denotes | Insulin |
| T93 | 517-524 | P01331 | denotes | Insulin |
| T94 | 517-524 | P01314 | denotes | Insulin |
| T95 | 517-524 | P01320 | denotes | Insulin |
| T96 | 517-524 | P01318 | denotes | Insulin |
| T97 | 517-524 | P12703 | denotes | Insulin |
| T98 | 517-524 | C0HJI4 | denotes | Insulin |
| T99 | 517-524 | P30406 | denotes | Insulin |
| T100 | 517-524 | C0HJU0 | denotes | Insulin |
| T101 | 517-524 | P68992 | denotes | Insulin |
| T102 | 517-524 | P67970 | denotes | Insulin |
| T103 | 517-524 | P18109 | denotes | Insulin |
| T104 | 517-524 | Q9TQY7 | denotes | Insulin |
| T105 | 517-524 | O73727 | denotes | Insulin |
| T106 | 517-524 | P01329 | denotes | Insulin |
| T107 | 517-524 | P01324 | denotes | Insulin |
| T109 | 517-524 | P01335 | denotes | Insulin |
| T110 | 517-524 | P68243 | denotes | Insulin |
| T111 | 517-524 | P67972 | denotes | Insulin |
| T112 | 517-524 | P29335 | denotes | Insulin |
| T113 | 517-524 | P01342 | denotes | Insulin |
| T114 | 517-524 | P69048 | denotes | Insulin |
| T115 | 517-524 | P01313 | denotes | Insulin |
| T116 | 517-524 | P01316 | denotes | Insulin |
| T117 | 517-524 | P17715 | denotes | Insulin |
| T118 | 517-524 | P30407 | denotes | Insulin |
| T119 | 517-524 | P01339 | denotes | Insulin |
| T121 | 517-524 | P81025 | denotes | Insulin |
| T122 | 517-524 | P69045 | denotes | Insulin |
| T123 | 517-524 | P01317 | denotes | Insulin |
| T124 | 517-524 | P01310 | denotes | Insulin |
| T125 | 517-524 | Q98TA8 | denotes | Insulin |
| T126 | 517-524 | P67969 | denotes | Insulin |
| T127 | 517-524 | P0C236 | denotes | Insulin |
| T50 | 517-524 | CHEBI:5931 | denotes | Insulin |
| T56 | 517-524 | D007328 | denotes | Insulin |
| T88 | 517-524 | CHEBI:145810 | denotes | Insulin |
| T108 | 517-524 | D007328 | denotes | Insulin |
| T120 | 517-524 | GO:0016088 | denotes | Insulin |
| T130 | 545-552 | 4850 | denotes | glucose |
| T128 | 545-552 | D005947 | denotes | glucose |
| T129 | 545-552 | D005947 | denotes | glucose |
| T131 | 545-552 | CHEBI:42758 | denotes | glucose |
| T132 | 545-552 | CHEBI:4167 | denotes | glucose |
| T133 | 545-552 | CHEBI:17234 | denotes | glucose |
| T134 | 545-559 | GO:0046323 | denotes | glucose uptake |
| T140 | 578-585 | 114202 | denotes | lactate |
| T137 | 578-585 | D019344 | denotes | lactate |
| T138 | 578-585 | CHEBI:16651 | denotes | lactate |
| T139 | 578-585 | D019344 | denotes | lactate |
| T141 | 578-585 | CHEBI:24996 | denotes | lactate |
| T142 | 622-629 | P51463 | denotes | insulin |
| T143 | 622-629 | Q91XI3 | denotes | insulin |
| T144 | 622-629 | P01308 | denotes | insulin |
| T145 | 622-629 | P01340 | denotes | insulin |
| T146 | 622-629 | P07453 | denotes | insulin |
| T147 | 622-629 | P68988 | denotes | insulin |
| T148 | 622-629 | P21563 | denotes | insulin |
| T149 | 622-629 | P68245 | denotes | insulin |
| T150 | 622-629 | P68990 | denotes | insulin |
| T152 | 622-629 | P09476 | denotes | insulin |
| T153 | 622-629 | P69047 | denotes | insulin |
| T154 | 622-629 | Q8HXV2 | denotes | insulin |
| T155 | 622-629 | P12705 | denotes | insulin |
| T156 | 622-629 | P68987 | denotes | insulin |
| T158 | 622-629 | Q9NDE7 | denotes | insulin |
| T159 | 622-629 | P13190 | denotes | insulin |
| T160 | 622-629 | P01321 | denotes | insulin |
| T161 | 622-629 | C0HJT9 | denotes | insulin |
| T162 | 622-629 | P81423 | denotes | insulin |
| T163 | 622-629 | P01327 | denotes | insulin |
| T164 | 622-629 | P41522 | denotes | insulin |
| T165 | 622-629 | C0HJI1 | denotes | insulin |
| T166 | 622-629 | P01336 | denotes | insulin |
| T167 | 622-629 | P67974 | denotes | insulin |
| T168 | 622-629 | P69046 | denotes | insulin |
| T169 | 622-629 | P12704 | denotes | insulin |
| T170 | 622-629 | P42633 | denotes | insulin |
| T171 | 622-629 | P67968 | denotes | insulin |
| T172 | 622-629 | P01334 | denotes | insulin |
| T173 | 622-629 | P67973 | denotes | insulin |
| T174 | 622-629 | P01328 | denotes | insulin |
| T175 | 622-629 | P81881 | denotes | insulin |
| T176 | 622-629 | P01330 | denotes | insulin |
| T177 | 622-629 | Q9W7R2 | denotes | insulin |
| T178 | 622-629 | P09477 | denotes | insulin |
| T179 | 622-629 | P01311 | denotes | insulin |
| T180 | 622-629 | P01315 | denotes | insulin |
| T181 | 622-629 | P06306 | denotes | insulin |
| T182 | 622-629 | P01319 | denotes | insulin |
| T183 | 622-629 | Q6YK33 | denotes | insulin |
| T184 | 622-629 | P67971 | denotes | insulin |
| T185 | 622-629 | Q62587 | denotes | insulin |
| T186 | 622-629 | P68991 | denotes | insulin |
| T187 | 622-629 | P12708 | denotes | insulin |
| T188 | 622-629 | P04667 | denotes | insulin |
| T190 | 622-629 | P68989 | denotes | insulin |
| T191 | 622-629 | P01333 | denotes | insulin |
| T192 | 622-629 | PR:000009054 | denotes | insulin |
| T193 | 622-629 | P30410 | denotes | insulin |
| T194 | 622-629 | P01331 | denotes | insulin |
| T195 | 622-629 | P01314 | denotes | insulin |
| T196 | 622-629 | P01320 | denotes | insulin |
| T197 | 622-629 | P01318 | denotes | insulin |
| T198 | 622-629 | P12703 | denotes | insulin |
| T199 | 622-629 | C0HJI4 | denotes | insulin |
| T200 | 622-629 | P30406 | denotes | insulin |
| T201 | 622-629 | C0HJU0 | denotes | insulin |
| T202 | 622-629 | P68992 | denotes | insulin |
| T203 | 622-629 | P67970 | denotes | insulin |
| T204 | 622-629 | P18109 | denotes | insulin |
| T205 | 622-629 | Q9TQY7 | denotes | insulin |
| T206 | 622-629 | O73727 | denotes | insulin |
| T207 | 622-629 | P01329 | denotes | insulin |
| T208 | 622-629 | P01324 | denotes | insulin |
| T210 | 622-629 | P01335 | denotes | insulin |
| T211 | 622-629 | P68243 | denotes | insulin |
| T212 | 622-629 | P67972 | denotes | insulin |
| T213 | 622-629 | P29335 | denotes | insulin |
| T214 | 622-629 | P01342 | denotes | insulin |
| T215 | 622-629 | P69048 | denotes | insulin |
| T216 | 622-629 | P01313 | denotes | insulin |
| T217 | 622-629 | P01316 | denotes | insulin |
| T218 | 622-629 | P17715 | denotes | insulin |
| T219 | 622-629 | P30407 | denotes | insulin |
| T220 | 622-629 | P01339 | denotes | insulin |
| T222 | 622-629 | P81025 | denotes | insulin |
| T223 | 622-629 | P69045 | denotes | insulin |
| T224 | 622-629 | P01317 | denotes | insulin |
| T225 | 622-629 | P01310 | denotes | insulin |
| T226 | 622-629 | Q98TA8 | denotes | insulin |
| T227 | 622-629 | P67969 | denotes | insulin |
| T228 | 622-629 | P0C236 | denotes | insulin |
| T151 | 622-629 | CHEBI:5931 | denotes | insulin |
| T157 | 622-629 | D007328 | denotes | insulin |
| T189 | 622-629 | CHEBI:145810 | denotes | insulin |
| T209 | 622-629 | D007328 | denotes | insulin |
| T221 | 622-629 | GO:0016088 | denotes | insulin |
| T231 | 664-671 | 4850 | denotes | glucose |
| T229 | 664-671 | D005947 | denotes | glucose |
| T230 | 664-671 | D005947 | denotes | glucose |
| T232 | 664-671 | CHEBI:42758 | denotes | glucose |
| T233 | 664-671 | CHEBI:4167 | denotes | glucose |
| T234 | 664-671 | CHEBI:17234 | denotes | glucose |
| T238 | 682-689 | 114202 | denotes | lactate |
| T235 | 682-689 | D019344 | denotes | lactate |
| T236 | 682-689 | CHEBI:16651 | denotes | lactate |
| T237 | 682-689 | D019344 | denotes | lactate |
| T239 | 682-689 | CHEBI:24996 | denotes | lactate |
| T242 | 756-763 | 4850 | denotes | glucose |
| T240 | 756-763 | D005947 | denotes | glucose |
| T241 | 756-763 | D005947 | denotes | glucose |
| T243 | 756-763 | CHEBI:42758 | denotes | glucose |
| T244 | 756-763 | CHEBI:4167 | denotes | glucose |
| T245 | 756-763 | CHEBI:17234 | denotes | glucose |
| T249 | 795-802 | 114202 | denotes | lactate |
| T246 | 795-802 | D019344 | denotes | lactate |
| T247 | 795-802 | CHEBI:16651 | denotes | lactate |
| T248 | 795-802 | D019344 | denotes | lactate |
| T250 | 795-802 | CHEBI:24996 | denotes | lactate |
| T253 | 853-860 | 4850 | denotes | glucose |
| T251 | 853-860 | D005947 | denotes | glucose |
| T252 | 853-860 | D005947 | denotes | glucose |
| T254 | 853-860 | CHEBI:42758 | denotes | glucose |
| T255 | 853-860 | CHEBI:4167 | denotes | glucose |
| T256 | 853-860 | CHEBI:17234 | denotes | glucose |
| T259 | 909-916 | 4850 | denotes | glucose |
| T257 | 909-916 | D005947 | denotes | glucose |
| T258 | 909-916 | D005947 | denotes | glucose |
| T260 | 909-916 | CHEBI:42758 | denotes | glucose |
| T261 | 909-916 | CHEBI:4167 | denotes | glucose |
| T262 | 909-916 | CHEBI:17234 | denotes | glucose |
| T263 | 909-927 | GO:0006006 | denotes | glucose metabolism |
| T268 | 948-955 | 114202 | denotes | lactate |
| T265 | 948-955 | D019344 | denotes | lactate |
| T266 | 948-955 | CHEBI:16651 | denotes | lactate |
| T267 | 948-955 | D019344 | denotes | lactate |
| T269 | 948-955 | CHEBI:24996 | denotes | lactate |
| T273 | 1024-1031 | 114202 | denotes | lactate |
| T275 | 1024-1045 | D007770 | denotes | lactate dehydrogenase |
| T276 | 1032-1045 | A0A5C1RDA6 | denotes | dehydrogenase |
| T279 | 1066-1069 | CHEBI:24021 | denotes | fat |
| T280 | 1066-1074 | UBERON:0003916 | denotes | fat body |
| T281 | 1066-1074 | UBERON:0003917 | denotes | fat body |
| T282 | 1078-1088 | 2294143 | denotes | Drosophila |
| T283 | 1078-1088 | 504603 | denotes | Drosophila |
| T284 | 1078-1088 | 2294139 | denotes | Drosophila |
| T285 | 1078-1088 | 2294145 | denotes | Drosophila |
| T286 | 1078-1088 | 2294141 | denotes | Drosophila |
| T287 | 1078-1088 | 2294142 | denotes | Drosophila |
| T288 | 1078-1088 | 2294144 | denotes | Drosophila |
| T289 | 1078-1088 | 2294140 | denotes | Drosophila |
| T290 | 1078-1088 | D004330 | denotes | Drosophila |
| T291 | 1078-1088 | 2080301 | denotes | Drosophila |
| T292 | 1089-1094 | D004175 | denotes | flies |
| T296 | 1115-1122 | 114202 | denotes | lactate |
| T293 | 1115-1122 | D019344 | denotes | lactate |
| T294 | 1115-1122 | CHEBI:16651 | denotes | lactate |
| T295 | 1115-1122 | D019344 | denotes | lactate |
| T297 | 1115-1122 | CHEBI:24996 | denotes | lactate |
| T298 | 1136-1146 | UBERON:0000468 | denotes | whole-body |
| T299 | 1136-1146 | UBERON:0013702 | denotes | whole-body |
| T302 | 1147-1154 | 4850 | denotes | glucose |
| T300 | 1147-1154 | D005947 | denotes | glucose |
| T301 | 1147-1154 | D005947 | denotes | glucose |
| T303 | 1147-1154 | CHEBI:42758 | denotes | glucose |
| T304 | 1147-1154 | CHEBI:4167 | denotes | glucose |
| T305 | 1147-1154 | CHEBI:17234 | denotes | glucose |
| T309 | 1194-1201 | 114202 | denotes | lactate |
| T306 | 1194-1201 | D019344 | denotes | lactate |
| T307 | 1194-1201 | CHEBI:16651 | denotes | lactate |
| T308 | 1194-1201 | D019344 | denotes | lactate |
| T310 | 1194-1201 | CHEBI:24996 | denotes | lactate |
| T312 | 1248-1262 | UBERON:0001013 | denotes | adipose tissue |
| T314 | 1270-1275 | CHEBI:18059 | denotes | lipid |
| T315 | 1270-1283 | GO:0019915 | denotes | lipid storage |
PubMed_ArguminSci
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 69-170 | DRI_Background | denotes | Adipose tissue is essential for whole-body glucose homeostasis, with a primary role in lipid storage. |
| T2 | 171-361 | DRI_Background | denotes | It has been previously observed that lactate production is also an important metabolic feature of adipocytes, but its relationship to adipose and whole-body glucose disposal remains unclear. |
| T3 | 362-516 | DRI_Background | denotes | Therefore, using a combination of metabolic labeling techniques, here we closely examined lactate production of cultured and primary mammalian adipocytes. |
| T4 | 517-672 | DRI_Background | denotes | Insulin treatment increased glucose uptake and conversion to lactate, with the latter responding more to insulin than did other metabolic fates of glucose. |
| T5 | 673-928 | DRI_Challenge | denotes | However, lactate production did not just serve as a mechanism to dispose of excess glucose, because we also observed that lactate production in adipocytes did not solely depend on glucose availability and even occurred independently of glucose metabolism. |
| T6 | 929-996 | DRI_Approach | denotes | This suggests that lactate production is prioritized in adipocytes. |
| T7 | 997-1164 | DRI_Background | denotes | Furthermore, knocking down lactate dehydrogenase specifically in the fat body of Drosophila flies lowered circulating lactate and improved whole-body glucose disposal. |
| T8 | 1165-1296 | DRI_Background | denotes | These results emphasize that lactate production is an additional metabolic role of adipose tissue beyond lipid storage and release. |
Goldhamster2_Cellosaurus
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 22-23 | CVCL_6479|Finite_cell_line|Mus musculus | denotes | a |
| T2 | 138-139 | CVCL_6479|Finite_cell_line|Mus musculus | denotes | a |
| T3 | 174-177 | CVCL_6758|Undefined_cell_line_type|Cricetulus griseus | denotes | has |
| T4 | 174-177 | CVCL_E689|Transformed_cell_line|Homo sapiens | denotes | has |
| T5 | 235-237 | CVCL_8754|Cancer_cell_line|Homo sapiens | denotes | an |
| T6 | 235-237 | CVCL_H241|Cancer_cell_line|Homo sapiens | denotes | an |
| T7 | 379-380 | CVCL_6479|Finite_cell_line|Mus musculus | denotes | a |
| T8 | 406-414 | CVCL_3734|Finite_cell_line|Homo sapiens | denotes | labeling |
| T9 | 432-434 | CVCL_5M23|Cancer_cell_line|Mesocricetus auratus | denotes | we |
| T10 | 723-724 | CVCL_6479|Finite_cell_line|Mus musculus | denotes | a |
| T11 | 773-775 | CVCL_5M23|Cancer_cell_line|Mesocricetus auratus | denotes | we |
| T12 | 1216-1218 | CVCL_8754|Cancer_cell_line|Homo sapiens | denotes | an |
| T13 | 1216-1218 | CVCL_H241|Cancer_cell_line|Homo sapiens | denotes | an |
GlyCosmos6-Glycan-Motif-Image
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 112-119 | Glycan_Motif | denotes | glucose | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G15021LG |
| T2 | 328-335 | Glycan_Motif | denotes | glucose | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G15021LG |
| T3 | 545-552 | Glycan_Motif | denotes | glucose | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G15021LG |
| T4 | 664-671 | Glycan_Motif | denotes | glucose | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G15021LG |
| T5 | 756-763 | Glycan_Motif | denotes | glucose | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G15021LG |
| T6 | 853-860 | Glycan_Motif | denotes | glucose | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G15021LG |
| T7 | 909-916 | Glycan_Motif | denotes | glucose | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G15021LG |
| T8 | 1147-1154 | Glycan_Motif | denotes | glucose | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G15021LG |
GlyCosmos6-Glycan-Motif-Structure
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 112-119 | https://glytoucan.org/Structures/Glycans/G15021LG | denotes | glucose |
| T2 | 328-335 | https://glytoucan.org/Structures/Glycans/G15021LG | denotes | glucose |
| T3 | 545-552 | https://glytoucan.org/Structures/Glycans/G15021LG | denotes | glucose |
| T4 | 664-671 | https://glytoucan.org/Structures/Glycans/G15021LG | denotes | glucose |
| T5 | 756-763 | https://glytoucan.org/Structures/Glycans/G15021LG | denotes | glucose |
| T6 | 853-860 | https://glytoucan.org/Structures/Glycans/G15021LG | denotes | glucose |
| T7 | 909-916 | https://glytoucan.org/Structures/Glycans/G15021LG | denotes | glucose |
| T8 | 1147-1154 | https://glytoucan.org/Structures/Glycans/G15021LG | denotes | glucose |
sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-68 | Sentence | denotes | Lactate production is a prioritized feature of adipocyte metabolism. |
| T2 | 69-170 | Sentence | denotes | Adipose tissue is essential for whole-body glucose homeostasis, with a primary role in lipid storage. |
| T3 | 171-361 | Sentence | denotes | It has been previously observed that lactate production is also an important metabolic feature of adipocytes, but its relationship to adipose and whole-body glucose disposal remains unclear. |
| T4 | 362-516 | Sentence | denotes | Therefore, using a combination of metabolic labeling techniques, here we closely examined lactate production of cultured and primary mammalian adipocytes. |
| T5 | 517-672 | Sentence | denotes | Insulin treatment increased glucose uptake and conversion to lactate, with the latter responding more to insulin than did other metabolic fates of glucose. |
| T6 | 673-928 | Sentence | denotes | However, lactate production did not just serve as a mechanism to dispose of excess glucose, because we also observed that lactate production in adipocytes did not solely depend on glucose availability and even occurred independently of glucose metabolism. |
| T7 | 929-996 | Sentence | denotes | This suggests that lactate production is prioritized in adipocytes. |
| T8 | 997-1164 | Sentence | denotes | Furthermore, knocking down lactate dehydrogenase specifically in the fat body of Drosophila flies lowered circulating lactate and improved whole-body glucose disposal. |
| T9 | 1165-1296 | Sentence | denotes | These results emphasize that lactate production is an additional metabolic role of adipose tissue beyond lipid storage and release. |
Glycosmos6-MAT
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 69-83 | http://purl.obolibrary.org/obo/MAT_0000015 | denotes | Adipose tissue |
| T2 | 1248-1262 | http://purl.obolibrary.org/obo/MAT_0000015 | denotes | adipose tissue |
Anatomy-MAT
| Id | Subject | Object | Predicate | Lexical cue | mat_id |
|---|---|---|---|---|---|
| T1 | 69-83 | Body_part | denotes | Adipose tissue | http://purl.obolibrary.org/obo/MAT_0000015 |
| T2 | 1248-1262 | Body_part | denotes | adipose tissue | http://purl.obolibrary.org/obo/MAT_0000015 |
NCBITAXON
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 1078-1088 | OrganismTaxon | denotes | Drosophila | 2081351|32281|7215 |
Anatomy-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 47-56 | Body_part | denotes | adipocyte | http://purl.obolibrary.org/obo/CL_0000136 |
| T2 | 69-83 | Body_part | denotes | Adipose tissue | http://purl.obolibrary.org/obo/UBERON_0001013 |
| T3 | 101-111 | Body_part | denotes | whole-body | http://purl.obolibrary.org/obo/UBERON_0000468|http://purl.obolibrary.org/obo/UBERON_0013702 |
| T5 | 269-279 | Body_part | denotes | adipocytes | http://purl.obolibrary.org/obo/CL_0000136 |
| T6 | 305-312 | Body_part | denotes | adipose | http://purl.obolibrary.org/obo/UBERON_0001013 |
| T7 | 317-327 | Body_part | denotes | whole-body | http://purl.obolibrary.org/obo/UBERON_0000468|http://purl.obolibrary.org/obo/UBERON_0013702 |
| T9 | 505-515 | Body_part | denotes | adipocytes | http://purl.obolibrary.org/obo/CL_0000136 |
| T10 | 817-827 | Body_part | denotes | adipocytes | http://purl.obolibrary.org/obo/CL_0000136 |
| T11 | 985-995 | Body_part | denotes | adipocytes | http://purl.obolibrary.org/obo/CL_0000136 |
| T12 | 1066-1074 | Body_part | denotes | fat body | http://purl.obolibrary.org/obo/UBERON_0003916|http://purl.obolibrary.org/obo/UBERON_0003917 |
| T14 | 1136-1146 | Body_part | denotes | whole-body | http://purl.obolibrary.org/obo/UBERON_0000468|http://purl.obolibrary.org/obo/UBERON_0013702 |
| T16 | 1248-1262 | Body_part | denotes | adipose tissue | http://purl.obolibrary.org/obo/UBERON_0001013 |
CL-cell
| Id | Subject | Object | Predicate | Lexical cue | cl_id |
|---|---|---|---|---|---|
| T1 | 47-56 | Cell | denotes | adipocyte | http://purl.obolibrary.org/obo/CL:0000136 |
| T2 | 269-279 | Cell | denotes | adipocytes | http://purl.obolibrary.org/obo/CL:0000136 |
| T3 | 505-515 | Cell | denotes | adipocytes | http://purl.obolibrary.org/obo/CL:0000136 |
| T4 | 817-827 | Cell | denotes | adipocytes | http://purl.obolibrary.org/obo/CL:0000136 |
| T5 | 985-995 | Cell | denotes | adipocytes | http://purl.obolibrary.org/obo/CL:0000136 |