PubMed:316310 JSONTXT

{"project":"Preeclampsia","denotations":[{"id":"PD-Preeclampsia-B_T1","span":{"begin":798,"end":810},"obj":"ORPHA:275555"}],"namespaces":[{"prefix":"ORPHA","uri":"www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=EN\u0026Expert="}],"text":"Radioimmunoassay of serum SP 1 and HPL in normal and abnormal pregnancies.\nSerum concentrations of the pregnancy-specific beta 1-glycoprotein (SP 1) and human placental lactogen (HPL) were measured by radioimmunoassay in 372 blood samples obtained from 40 women in the second half of a normal singleton pregnancy. The mean level of SP 1 steadily increased from 40 micrograms/ml in the 22nd week of pregnancy to 168 micrograms/ml in the 36th week of gestation and thereafter reached a plateau. The half-life of SP 1 during the first week after delivery was about 39 h. The clinical value of SP 1 in comparison to HPL estimations was assessed in a prospective study of a few high risk pregnancies. There were no significant differences between serum SP 1 and HPL levels in pregnancies complicated by preeclampsia with or without intrauterine growth retardation and in twin pregnancies. Serum HPL and SP 1 levels were equally effective in predicting placental insufficiency with fetal growth retardation."}

{"project":"Preeclampsia-compare","denotations":[{"id":"PD-Preeclampsia-B_T1","span":{"begin":798,"end":810},"obj":"ORPHA:275555"}],"namespaces":[{"prefix":"ORPHA","uri":"www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=EN\u0026Expert="}],"text":"Radioimmunoassay of serum SP 1 and HPL in normal and abnormal pregnancies.\nSerum concentrations of the pregnancy-specific beta 1-glycoprotein (SP 1) and human placental lactogen (HPL) were measured by radioimmunoassay in 372 blood samples obtained from 40 women in the second half of a normal singleton pregnancy. The mean level of SP 1 steadily increased from 40 micrograms/ml in the 22nd week of pregnancy to 168 micrograms/ml in the 36th week of gestation and thereafter reached a plateau. The half-life of SP 1 during the first week after delivery was about 39 h. The clinical value of SP 1 in comparison to HPL estimations was assessed in a prospective study of a few high risk pregnancies. There were no significant differences between serum SP 1 and HPL levels in pregnancies complicated by preeclampsia with or without intrauterine growth retardation and in twin pregnancies. Serum HPL and SP 1 levels were equally effective in predicting placental insufficiency with fetal growth retardation."}

{"project":"sentences","denotations":[{"id":"TextSentencer_T1","span":{"begin":0,"end":74},"obj":"Sentence"},{"id":"TextSentencer_T2","span":{"begin":75,"end":313},"obj":"Sentence"},{"id":"TextSentencer_T3","span":{"begin":314,"end":492},"obj":"Sentence"},{"id":"TextSentencer_T4","span":{"begin":493,"end":567},"obj":"Sentence"},{"id":"TextSentencer_T5","span":{"begin":568,"end":695},"obj":"Sentence"},{"id":"TextSentencer_T6","span":{"begin":696,"end":883},"obj":"Sentence"},{"id":"TextSentencer_T7","span":{"begin":884,"end":1001},"obj":"Sentence"},{"id":"T1","span":{"begin":0,"end":74},"obj":"Sentence"},{"id":"T2","span":{"begin":75,"end":313},"obj":"Sentence"},{"id":"T3","span":{"begin":314,"end":492},"obj":"Sentence"},{"id":"T4","span":{"begin":493,"end":567},"obj":"Sentence"},{"id":"T5","span":{"begin":568,"end":695},"obj":"Sentence"},{"id":"T6","span":{"begin":696,"end":883},"obj":"Sentence"},{"id":"T7","span":{"begin":884,"end":1001},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Radioimmunoassay of serum SP 1 and HPL in normal and abnormal pregnancies.\nSerum concentrations of the pregnancy-specific beta 1-glycoprotein (SP 1) and human placental lactogen (HPL) were measured by radioimmunoassay in 372 blood samples obtained from 40 women in the second half of a normal singleton pregnancy. The mean level of SP 1 steadily increased from 40 micrograms/ml in the 22nd week of pregnancy to 168 micrograms/ml in the 36th week of gestation and thereafter reached a plateau. The half-life of SP 1 during the first week after delivery was about 39 h. The clinical value of SP 1 in comparison to HPL estimations was assessed in a prospective study of a few high risk pregnancies. There were no significant differences between serum SP 1 and HPL levels in pregnancies complicated by preeclampsia with or without intrauterine growth retardation and in twin pregnancies. Serum HPL and SP 1 levels were equally effective in predicting placental insufficiency with fetal growth retardation."}

{"project":"UBERON-AE","denotations":[{"id":"PD-UBERON-AE-B_T1","span":{"begin":20,"end":25},"obj":"http://purl.obolibrary.org/obo/UBERON_0001977"},{"id":"PD-UBERON-AE-B_T2","span":{"begin":742,"end":747},"obj":"http://purl.obolibrary.org/obo/UBERON_0001977"},{"id":"PD-UBERON-AE-B_T3","span":{"begin":225,"end":230},"obj":"http://purl.obolibrary.org/obo/UBERON_0000178"}],"text":"Radioimmunoassay of serum SP 1 and HPL in normal and abnormal pregnancies.\nSerum concentrations of the pregnancy-specific beta 1-glycoprotein (SP 1) and human placental lactogen (HPL) were measured by radioimmunoassay in 372 blood samples obtained from 40 women in the second half of a normal singleton pregnancy. The mean level of SP 1 steadily increased from 40 micrograms/ml in the 22nd week of pregnancy to 168 micrograms/ml in the 36th week of gestation and thereafter reached a plateau. The half-life of SP 1 during the first week after delivery was about 39 h. The clinical value of SP 1 in comparison to HPL estimations was assessed in a prospective study of a few high risk pregnancies. There were no significant differences between serum SP 1 and HPL levels in pregnancies complicated by preeclampsia with or without intrauterine growth retardation and in twin pregnancies. Serum HPL and SP 1 levels were equally effective in predicting placental insufficiency with fetal growth retardation."}

{"project":"preeclampsia_genes","denotations":[{"id":"PD-PreeclampsiaGenes-B_T1","span":{"begin":103,"end":141},"obj":"HGNC:PSG8"},{"id":"PD-PreeclampsiaGenes-B_T2","span":{"begin":103,"end":141},"obj":"HGNC:PSG1"},{"id":"PD-PreeclampsiaGenes-B_T3","span":{"begin":103,"end":141},"obj":"HGNC:PSG3"},{"id":"PD-PreeclampsiaGenes-B_T4","span":{"begin":103,"end":141},"obj":"HGNC:PSG9"},{"id":"PD-PreeclampsiaGenes-B_T5","span":{"begin":103,"end":141},"obj":"HGNC:PSG2"},{"id":"PD-PreeclampsiaGenes-B_T6","span":{"begin":103,"end":141},"obj":"HGNC:PSG5"},{"id":"PD-PreeclampsiaGenes-B_T7","span":{"begin":103,"end":141},"obj":"HGNC:PSG4"},{"id":"PD-PreeclampsiaGenes-B_T8","span":{"begin":103,"end":141},"obj":"HGNC:PSG6"},{"id":"PD-PreeclampsiaGenes-B_T9","span":{"begin":103,"end":141},"obj":"HGNC:PSG11"},{"id":"PD-PreeclampsiaGenes-B_T10","span":{"begin":129,"end":141},"obj":"HGNC:GP2"}],"text":"Radioimmunoassay of serum SP 1 and HPL in normal and abnormal pregnancies.\nSerum concentrations of the pregnancy-specific beta 1-glycoprotein (SP 1) and human placental lactogen (HPL) were measured by radioimmunoassay in 372 blood samples obtained from 40 women in the second half of a normal singleton pregnancy. The mean level of SP 1 steadily increased from 40 micrograms/ml in the 22nd week of pregnancy to 168 micrograms/ml in the 36th week of gestation and thereafter reached a plateau. The half-life of SP 1 during the first week after delivery was about 39 h. The clinical value of SP 1 in comparison to HPL estimations was assessed in a prospective study of a few high risk pregnancies. There were no significant differences between serum SP 1 and HPL levels in pregnancies complicated by preeclampsia with or without intrauterine growth retardation and in twin pregnancies. Serum HPL and SP 1 levels were equally effective in predicting placental insufficiency with fetal growth retardation."}

{"project":"performance-test","denotations":[{"id":"PD-UBERON-AE-B_T1","span":{"begin":225,"end":230},"obj":"http://purl.obolibrary.org/obo/UBERON_0000178"},{"id":"PD-UBERON-AE-B_T2","span":{"begin":159,"end":168},"obj":"http://purl.obolibrary.org/obo/UBERON_0001987"},{"id":"PD-UBERON-AE-B_T3","span":{"begin":947,"end":956},"obj":"http://purl.obolibrary.org/obo/UBERON_0001987"},{"id":"PD-UBERON-AE-B_T4","span":{"begin":20,"end":25},"obj":"http://purl.obolibrary.org/obo/UBERON_0001977"},{"id":"PD-UBERON-AE-B_T5","span":{"begin":75,"end":80},"obj":"http://purl.obolibrary.org/obo/UBERON_0001977"},{"id":"PD-UBERON-AE-B_T6","span":{"begin":742,"end":747},"obj":"http://purl.obolibrary.org/obo/UBERON_0001977"},{"id":"PD-UBERON-AE-B_T7","span":{"begin":884,"end":889},"obj":"http://purl.obolibrary.org/obo/UBERON_0001977"}],"text":"Radioimmunoassay of serum SP 1 and HPL in normal and abnormal pregnancies.\nSerum concentrations of the pregnancy-specific beta 1-glycoprotein (SP 1) and human placental lactogen (HPL) were measured by radioimmunoassay in 372 blood samples obtained from 40 women in the second half of a normal singleton pregnancy. The mean level of SP 1 steadily increased from 40 micrograms/ml in the 22nd week of pregnancy to 168 micrograms/ml in the 36th week of gestation and thereafter reached a plateau. The half-life of SP 1 during the first week after delivery was about 39 h. The clinical value of SP 1 in comparison to HPL estimations was assessed in a prospective study of a few high risk pregnancies. There were no significant differences between serum SP 1 and HPL levels in pregnancies complicated by preeclampsia with or without intrauterine growth retardation and in twin pregnancies. Serum HPL and SP 1 levels were equally effective in predicting placental insufficiency with fetal growth retardation."}