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sonoma2

Id Subject Object Predicate Lexical cue
T0 41-87 GENE denotes sodium taurocholate cotransporting polypeptide
T1 76-98 DISEASE denotes polypeptide deficiency
T2 88-98 VAR denotes deficiency
T3 152-198 GENE denotes sodium taurocholate cotransporting polypeptide
T4 200-204 GENE denotes NTCP
T5 206-216 VAR denotes deficiency
T6 321-330 REG denotes resulting
T7 331-333 REG denotes in
T8 339-356 DISEASE denotes liver dysfunction
T9 617-621 GENE denotes NTCP
T10 622-632 VAR denotes deficiency
T11 809-813 GENE denotes NTCP
T12 814-823 VAR denotes deficient
T13 814-823 DISEASE denotes deficient
T14 841-848 GENE denotes SLC10A1
T15 854-862 VAR denotes mutation
T16 875-879 GENE denotes NTCP
T17 880-890 VAR denotes deficiency
T18 901-915 DISEASE denotes liver diseases
T19 921-928 REG denotes present
T20 956-966 REG denotes determined
T21 1003-1011 DISEASE denotes jaundice
T22 1170-1181 MPA denotes serum level
T23 1185-1200 MPA denotes total bile acid
T24 1205-1209 POSREG denotes high
T25 1243-1246 REG denotes had
T26 1256-1262 CPA denotes growth
T27 1267-1278 CPA denotes development
T28 1309-1318 REG denotes presented
T29 1332-1340 DISEASE denotes jaundice
T30 1361-1366 REG denotes found
T31 1370-1374 REG denotes have
T32 1375-1393 MPA denotes hyperbilirubinemia
T33 1375-1393 DISEASE denotes hyperbilirubinemia
T34 1450-1458 REG denotes revealed
T35 1468-1488 CPA denotes chronic inflammation
T36 1476-1488 DISEASE denotes inflammation
T37 1540-1545 REG denotes found
T38 1552-1561 REG denotes suffering
T39 1567-1577 DISEASE denotes gallstones
T40 1608-1612 GENE denotes NTCP
T41 1613-1623 VAR denotes deficiency
T42 1669-1675 REG denotes showed
T43 1684-1704 MPA denotes clinical expressions
T44 1714-1722 DISEASE denotes jaundice
T45 1761-1765 GENE denotes NTCP
T46 1766-1776 VAR denotes deficiency
T47 1833-1840 REG denotes similar
T48 1858-1881 DISEASE denotes hepatocellular jaundice
T49 1961-1971 DISEASE denotes gallstones
T50 1986-1992 REG denotes caused
T51 1996-2000 GENE denotes NTCP
T52 2001-2011 VAR denotes deficiency
R33 T44 T42 ThemeOf jaundice,showed
R34 T44 T43 ThemeOf jaundice,clinical expressions
R35 T45 T46 ThemeOf NTCP,deficiency
R36 T46 T47 ThemeOf deficiency,similar
R0 T0 T2 ThemeOf sodium taurocholate cotransporting polypeptide,deficiency
R1 T3 T5 ThemeOf sodium taurocholate cotransporting polypeptide,deficiency
R2 T4 T5 ThemeOf NTCP,deficiency
R3 T5 T7 CauseOf deficiency,in
R4 T8 T6 ThemeOf liver dysfunction,resulting
R5 T8 T7 ThemeOf liver dysfunction,in
R6 T9 T10 ThemeOf NTCP,deficiency
R7 T11 T12 ThemeOf NTCP,deficient
R8 T11 T15 ThemeOf NTCP,mutation
R9 T14 T15 ThemeOf SLC10A1,mutation
R10 T16 T17 ThemeOf NTCP,deficiency
R11 T18 T19 ThemeOf liver diseases,present
R12 T18 T20 ThemeOf liver diseases,determined
R13 T21 T19 ThemeOf jaundice,present
R14 T21 T20 ThemeOf jaundice,determined
R15 T23 T22 ThemeOf total bile acid,serum level
R16 T22 T24 ThemeOf serum level,high
R17 T23 T24 ThemeOf total bile acid,high
R18 T26 T25 ThemeOf growth,had
R19 T27 T26 ThemeOf development,growth
R20 T27 T25 ThemeOf development,had
R21 T29 T28 ThemeOf jaundice,presented
R22 T29 T30 ThemeOf jaundice,found
R23 T29 T31 ThemeOf jaundice,have
R24 T31 T30 ThemeOf have,found
R25 T32 T28 ThemeOf hyperbilirubinemia,presented
R26 T32 T30 ThemeOf hyperbilirubinemia,found
R27 T32 T31 ThemeOf hyperbilirubinemia,have
R28 T35 T34 ThemeOf chronic inflammation,revealed
R29 T39 T37 ThemeOf gallstones,found
R30 T39 T38 ThemeOf gallstones,suffering
R31 T40 T41 ThemeOf NTCP,deficiency
R32 T43 T42 ThemeOf clinical expressions,showed
R37 T48 T47 ThemeOf hepatocellular jaundice,similar
R38 T49 T50 ThemeOf gallstones,caused
R39 T51 T52 ThemeOf NTCP,deficiency
R40 T52 T50 CauseOf deficiency,caused

Inflammaging

Id Subject Object Predicate Lexical cue
T1 0-121 Sentence denotes Clinical and histopathologic features of sodium taurocholate cotransporting polypeptide deficiency in pediatric patients.
T2 122-264 Sentence denotes Until now, the recognition of sodium taurocholate cotransporting polypeptide (NTCP) deficiency has been mainly based on sporadic case reports.
T3 265-357 Sentence denotes It was previously believed to be mildly symptomatic and resulting in mild liver dysfunction.
T4 358-500 Sentence denotes However, to our knowledge, there have been no reports about the histopathologic and ultrastructural pathologic characteristics of the disease.
T5 501-863 Sentence denotes The aim of the study was to analyze the clinical, histopathologic and ultrastructural pathologic characteristics of NTCP deficiency in 13 pediatric patients.From August 2012 to October 2018, this retrospective study conducted in the Department of Pediatrics of Tongji Hospital, China analyzed the data of 13 NTCP deficient patients with an SLC10A1 gene mutation.
T6 864-1045 Sentence denotes Except for NTCP deficiency, no other liver diseases were present in the patients, which was determined by both a genetic testing panel for jaundice and by reviewing medical records.
T7 1046-1229 Sentence denotes The laboratory results, imaging, histopathologic, and ultrastructural pathologic information were recorded for analysis.The serum level of total bile acid was high in all 13 patients.
T8 1230-1279 Sentence denotes All patients had adequate growth and development.
T9 1280-1394 Sentence denotes Eight of the patients (8/13) presented with visible jaundice and 12 (12/13) were found to have hyperbilirubinemia.
T10 1395-1508 Sentence denotes A needle liver biopsy was performed in 11 cases, which revealed slightly chronic inflammation in all 11 patients.
T11 1509-1723 Sentence denotes One of the patients (1/13) was found to be suffering from gallstones.The data showed that although NTCP deficiency was often asymptomatic, some of the patients showed obvious clinical expressions, such as jaundice.
T12 1724-1882 Sentence denotes Among the 13 pediatric patients with NTCP deficiency, both the biochemical and histopathologic features were similar to those of mild hepatocellular jaundice.
T13 1883-2012 Sentence denotes In addition, it was determined that the clinical features in the patient with gallstones may have been caused by NTCP deficiency.
T1 0-121 Sentence denotes Clinical and histopathologic features of sodium taurocholate cotransporting polypeptide deficiency in pediatric patients.
T2 122-264 Sentence denotes Until now, the recognition of sodium taurocholate cotransporting polypeptide (NTCP) deficiency has been mainly based on sporadic case reports.
T3 265-357 Sentence denotes It was previously believed to be mildly symptomatic and resulting in mild liver dysfunction.
T4 358-500 Sentence denotes However, to our knowledge, there have been no reports about the histopathologic and ultrastructural pathologic characteristics of the disease.
T5 501-863 Sentence denotes The aim of the study was to analyze the clinical, histopathologic and ultrastructural pathologic characteristics of NTCP deficiency in 13 pediatric patients.From August 2012 to October 2018, this retrospective study conducted in the Department of Pediatrics of Tongji Hospital, China analyzed the data of 13 NTCP deficient patients with an SLC10A1 gene mutation.
T6 864-1045 Sentence denotes Except for NTCP deficiency, no other liver diseases were present in the patients, which was determined by both a genetic testing panel for jaundice and by reviewing medical records.
T7 1046-1229 Sentence denotes The laboratory results, imaging, histopathologic, and ultrastructural pathologic information were recorded for analysis.The serum level of total bile acid was high in all 13 patients.
T8 1230-1279 Sentence denotes All patients had adequate growth and development.
T9 1280-1394 Sentence denotes Eight of the patients (8/13) presented with visible jaundice and 12 (12/13) were found to have hyperbilirubinemia.
T10 1395-1508 Sentence denotes A needle liver biopsy was performed in 11 cases, which revealed slightly chronic inflammation in all 11 patients.
T11 1509-1723 Sentence denotes One of the patients (1/13) was found to be suffering from gallstones.The data showed that although NTCP deficiency was often asymptomatic, some of the patients showed obvious clinical expressions, such as jaundice.
T12 1724-1882 Sentence denotes Among the 13 pediatric patients with NTCP deficiency, both the biochemical and histopathologic features were similar to those of mild hepatocellular jaundice.
T13 1883-2012 Sentence denotes In addition, it was determined that the clinical features in the patient with gallstones may have been caused by NTCP deficiency.