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GlyCosmos6-Glycan-Motif-Image

Id Subject Object Predicate Lexical cue image
T1 818-829 Glycan_Motif denotes sialic acid https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G81533KY
T2 1661-1672 Glycan_Motif denotes sialic acid https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G81533KY
T3 1780-1791 Glycan_Motif denotes sialic acid https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G81533KY

sentences

Id Subject Object Predicate Lexical cue
T1 0-77 Sentence denotes Asparagine-linked oligosaccharides on lutropin, follitropin, and thyrotropin.
T2 78-80 Sentence denotes I.
T3 81-212 Sentence denotes Structural elucidation of the sulfated and sialylated oligosaccharides on bovine, ovine, and human pituitary glycoprotein hormones.
T4 213-456 Sentence denotes We have elucidated the structures of the anionic asparagine-linked oligosaccharides present on the glycoprotein hormones lutropin (luteinizing hormone), follitropin (follicle-stimulating hormone), and thyrotropin (thyroid-stimulating hormone).
T5 457-621 Sentence denotes Purified hormones, isolated from bovine, ovine, and human pituitaries, were digested with N-glycanase, and the released oligosaccharides were reduced with NaB[3H]4.
T6 622-839 Sentence denotes The 3H-labeled oligosaccharides from each hormone were then fractionated by anion-exchange high performance liquid chromatography (HPLC) into populations differing in the number of sulfate and/or sialic acid moieties.
T7 840-1075 Sentence denotes The anionic oligosaccharides were further purified as well as structurally characterized using a variety of preparative and analytical techniques, including HPLC, endo- and exoglycosidase digestions, and lectin affinity chromatography.
T8 1076-1345 Sentence denotes The sulfated, sialylated, and sulfated/sialylated structures, which together comprised 67-90% of the asparagine-linked oligosaccharides on the pituitary glycoprotein hormones, were highly heterogeneous and displayed hormone- as well as animal species-specific features.
T9 1346-1491 Sentence denotes The sulfated oligosaccharides consisted of hybrid and complex type oligosaccharides with one or two branches terminating in SO4-4GalNAc beta 1,4.
T10 1492-1682 Sentence denotes In contrast, the sialylated oligosaccharides consisted of a wide array of differing structures containing two or three peripheral branches as well as one, two, or three sialic acid moieties.
T11 1683-1849 Sentence denotes A previously uncharacterized dibranched oligosaccharide, bearing one residue each of sulfate and sialic acid, was found on all of the hormones except bovine lutropin.
T12 1850-2082 Sentence denotes In this study, we describe the purification and detailed structural characterizations of the sulfated, sialylated, and sulfated/sialylated oligosaccharides found on lutropin, follitropin, and thyrotropin from several animal species.
T13 2083-2151 Sentence denotes In the accompanying paper (Green, E.D., and Baenziger, J.U.(1987) J.
T14 2152-2157 Sentence denotes Biol.
T15 2158-2163 Sentence denotes Chem.
T16 2164-2447 Sentence denotes 262, 36-44) we demonstrate the marked quantitative differences among the pituitary glycoprotein hormones in terms of sulfation, sialylation, and underlying oligosaccharide structures, as well as provide evidence for site-specific synthesis of oligosaccharides on individual hormones.
T1 0-77 Sentence denotes Asparagine-linked oligosaccharides on lutropin, follitropin, and thyrotropin.
T2 78-80 Sentence denotes I.
T3 81-212 Sentence denotes Structural elucidation of the sulfated and sialylated oligosaccharides on bovine, ovine, and human pituitary glycoprotein hormones.
T4 213-456 Sentence denotes We have elucidated the structures of the anionic asparagine-linked oligosaccharides present on the glycoprotein hormones lutropin (luteinizing hormone), follitropin (follicle-stimulating hormone), and thyrotropin (thyroid-stimulating hormone).
T5 457-621 Sentence denotes Purified hormones, isolated from bovine, ovine, and human pituitaries, were digested with N-glycanase, and the released oligosaccharides were reduced with NaB[3H]4.
T6 622-839 Sentence denotes The 3H-labeled oligosaccharides from each hormone were then fractionated by anion-exchange high performance liquid chromatography (HPLC) into populations differing in the number of sulfate and/or sialic acid moieties.
T7 840-1075 Sentence denotes The anionic oligosaccharides were further purified as well as structurally characterized using a variety of preparative and analytical techniques, including HPLC, endo- and exoglycosidase digestions, and lectin affinity chromatography.
T8 1076-1345 Sentence denotes The sulfated, sialylated, and sulfated/sialylated structures, which together comprised 67-90% of the asparagine-linked oligosaccharides on the pituitary glycoprotein hormones, were highly heterogeneous and displayed hormone- as well as animal species-specific features.
T9 1346-1491 Sentence denotes The sulfated oligosaccharides consisted of hybrid and complex type oligosaccharides with one or two branches terminating in SO4-4GalNAc beta 1,4.
T10 1492-1682 Sentence denotes In contrast, the sialylated oligosaccharides consisted of a wide array of differing structures containing two or three peripheral branches as well as one, two, or three sialic acid moieties.
T11 1683-1849 Sentence denotes A previously uncharacterized dibranched oligosaccharide, bearing one residue each of sulfate and sialic acid, was found on all of the hormones except bovine lutropin.
T12 1850-2082 Sentence denotes In this study, we describe the purification and detailed structural characterizations of the sulfated, sialylated, and sulfated/sialylated oligosaccharides found on lutropin, follitropin, and thyrotropin from several animal species.
T13 2083-2151 Sentence denotes In the accompanying paper (Green, E.D., and Baenziger, J.U.(1987) J.
T14 2152-2157 Sentence denotes Biol.
T15 2158-2163 Sentence denotes Chem.
T16 2164-2447 Sentence denotes 262, 36-44) we demonstrate the marked quantitative differences among the pituitary glycoprotein hormones in terms of sulfation, sialylation, and underlying oligosaccharide structures, as well as provide evidence for site-specific synthesis of oligosaccharides on individual hormones.

GlyCosmos6-Glycan-Motif-Structure

Id Subject Object Predicate Lexical cue
T1 818-829 https://glytoucan.org/Structures/Glycans/G81533KY denotes sialic acid
T2 1661-1672 https://glytoucan.org/Structures/Glycans/G81533KY denotes sialic acid
T3 1780-1791 https://glytoucan.org/Structures/Glycans/G81533KY denotes sialic acid

Glycosmos6-MAT

Id Subject Object Predicate Lexical cue
T1 180-189 http://purl.obolibrary.org/obo/MAT_0000077 denotes pituitary
T2 427-434 http://purl.obolibrary.org/obo/MAT_0000081 denotes thyroid
T3 515-526 http://purl.obolibrary.org/obo/MAT_0000077 denotes pituitaries
T4 1219-1228 http://purl.obolibrary.org/obo/MAT_0000077 denotes pituitary
T5 2237-2246 http://purl.obolibrary.org/obo/MAT_0000077 denotes pituitary

NGLY1-deficiency

Id Subject Object Predicate Lexical cue
PD-NGLY1-deficiency-B_T1 547-558 hgnc:17646 denotes N-glycanase

mondo_disease

Id Subject Object Predicate Lexical cue mondo_id
T1 180-189 Disease denotes pituitary http://purl.obolibrary.org/obo/MONDO_0021156
T2 1219-1228 Disease denotes pituitary http://purl.obolibrary.org/obo/MONDO_0021156
T3 2237-2246 Disease denotes pituitary http://purl.obolibrary.org/obo/MONDO_0021156

Anatomy-MAT

Id Subject Object Predicate Lexical cue mat_id
T1 180-189 Body_part denotes pituitary http://purl.obolibrary.org/obo/MAT_0000077
T2 427-434 Body_part denotes thyroid http://purl.obolibrary.org/obo/MAT_0000081
T3 515-526 Body_part denotes pituitaries http://purl.obolibrary.org/obo/MAT_0000077
T4 1219-1228 Body_part denotes pituitary http://purl.obolibrary.org/obo/MAT_0000077
T5 2237-2246 Body_part denotes pituitary http://purl.obolibrary.org/obo/MAT_0000077

NCBITAXON

Id Subject Object Predicate Lexical cue db_id
T1 155-161 OrganismTaxon denotes bovine 9913
T2 174-179 OrganismTaxon denotes human 9606
T3 490-496 OrganismTaxon denotes bovine 9913
T4 509-514 OrganismTaxon denotes human 9606
T5 1833-1839 OrganismTaxon denotes bovine 9913

Lectin-Jamboree-Sentence

Id Subject Object Predicate Lexical cue
T1 0-77 Sentence denotes Asparagine-linked oligosaccharides on lutropin, follitropin, and thyrotropin.
T2 78-212 Sentence denotes I. Structural elucidation of the sulfated and sialylated oligosaccharides on bovine, ovine, and human pituitary glycoprotein hormones.
T3 213-456 Sentence denotes We have elucidated the structures of the anionic asparagine-linked oligosaccharides present on the glycoprotein hormones lutropin (luteinizing hormone), follitropin (follicle-stimulating hormone), and thyrotropin (thyroid-stimulating hormone).
T4 457-621 Sentence denotes Purified hormones, isolated from bovine, ovine, and human pituitaries, were digested with N-glycanase, and the released oligosaccharides were reduced with NaB[3H]4.
T5 622-839 Sentence denotes The 3H-labeled oligosaccharides from each hormone were then fractionated by anion-exchange high performance liquid chromatography (HPLC) into populations differing in the number of sulfate and/or sialic acid moieties.
T6 840-1075 Sentence denotes The anionic oligosaccharides were further purified as well as structurally characterized using a variety of preparative and analytical techniques, including HPLC, endo- and exoglycosidase digestions, and lectin affinity chromatography.
T7 1076-1345 Sentence denotes The sulfated, sialylated, and sulfated/sialylated structures, which together comprised 67-90% of the asparagine-linked oligosaccharides on the pituitary glycoprotein hormones, were highly heterogeneous and displayed hormone- as well as animal species-specific features.
T8 1346-1491 Sentence denotes The sulfated oligosaccharides consisted of hybrid and complex type oligosaccharides with one or two branches terminating in SO4-4GalNAc beta 1,4.
T9 1492-1682 Sentence denotes In contrast, the sialylated oligosaccharides consisted of a wide array of differing structures containing two or three peripheral branches as well as one, two, or three sialic acid moieties.
T10 1683-1849 Sentence denotes A previously uncharacterized dibranched oligosaccharide, bearing one residue each of sulfate and sialic acid, was found on all of the hormones except bovine lutropin.
T11 1850-2082 Sentence denotes In this study, we describe the purification and detailed structural characterizations of the sulfated, sialylated, and sulfated/sialylated oligosaccharides found on lutropin, follitropin, and thyrotropin from several animal species.
T12 2083-2447 Sentence denotes In the accompanying paper (Green, E.D., and Baenziger, J.U.(1987) J. Biol. Chem. 262, 36-44) we demonstrate the marked quantitative differences among the pituitary glycoprotein hormones in terms of sulfation, sialylation, and underlying oligosaccharide structures, as well as provide evidence for site-specific synthesis of oligosaccharides on individual hormones.

Anatomy-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 180-189 Body_part denotes pituitary http://purl.obolibrary.org/obo/UBERON_0000007
T2 379-387 Body_part denotes follicle http://purl.obolibrary.org/obo/UBERON_0003199|http://purl.obolibrary.org/obo/UBERON_0036150
T4 427-434 Body_part denotes thyroid http://purl.obolibrary.org/obo/UBERON_0002046
T5 1219-1228 Body_part denotes pituitary http://purl.obolibrary.org/obo/UBERON_0000007
T6 2237-2246 Body_part denotes pituitary http://purl.obolibrary.org/obo/UBERON_0000007