PubMed:31129139 / 131-449 JSONTXT

{"project":"PubMed_Structured_Abstracts","denotations":[{"id":"T1","span":{"begin":0,"end":318},"obj":"OBJECTIVE"}],"text":"Acetaminophen (APAP) overdose is the most frequent cause of drug-induced liver damage. Magnolia officinalis is a traditional hepatoprotective Chinese medicine and Honokiol (HO) is the major active constituent. The present study was to investigate the effect of HO on APAP-induced hepatotoxicity and related mechanisms."}

{"project":"Goldhamster2_Cellosaurus","denotations":[{"id":"T1","span":{"begin":111,"end":112},"obj":"CVCL_6479|Finite_cell_line|Mus musculus"},{"id":"T2","span":{"begin":173,"end":175},"obj":"CVCL_M698|Cancer_cell_line|Homo sapiens"},{"id":"T3","span":{"begin":190,"end":196},"obj":"CVCL_C410|Hybridoma|Mus musculus"},{"id":"T4","span":{"begin":261,"end":263},"obj":"CVCL_M698|Cancer_cell_line|Homo sapiens"}],"text":"Acetaminophen (APAP) overdose is the most frequent cause of drug-induced liver damage. Magnolia officinalis is a traditional hepatoprotective Chinese medicine and Honokiol (HO) is the major active constituent. The present study was to investigate the effect of HO on APAP-induced hepatotoxicity and related mechanisms."}

{"project":"GoldHamster","denotations":[{"id":"T19","span":{"begin":0,"end":13},"obj":"161"},{"id":"T18","span":{"begin":0,"end":13},"obj":"D000082"},{"id":"T20","span":{"begin":0,"end":13},"obj":"D000082"},{"id":"T21","span":{"begin":0,"end":13},"obj":"CHEBI:46195"},{"id":"T22","span":{"begin":15,"end":19},"obj":"D000082"},{"id":"T23","span":{"begin":15,"end":19},"obj":"D000082"},{"id":"T24","span":{"begin":15,"end":19},"obj":"CHEBI:46195"},{"id":"T25","span":{"begin":60,"end":64},"obj":"CHEBI:23888"},{"id":"T26","span":{"begin":60,"end":78},"obj":"D056486"},{"id":"T27","span":{"begin":60,"end":78},"obj":"D056486"},{"id":"T28","span":{"begin":73,"end":78},"obj":"UBERON:0002107"},{"id":"T30","span":{"begin":87,"end":107},"obj":"85864"},{"id":"T31","span":{"begin":87,"end":107},"obj":"D031566"},{"id":"T32","span":{"begin":150,"end":158},"obj":"CHEBI:23888"},{"id":"T33","span":{"begin":163,"end":171},"obj":"C005499"},{"id":"T34","span":{"begin":163,"end":171},"obj":"C005499"},{"id":"T35","span":{"begin":163,"end":171},"obj":"CHEBI:5759"},{"id":"T36","span":{"begin":267,"end":271},"obj":"D000082"},{"id":"T37","span":{"begin":267,"end":271},"obj":"D000082"},{"id":"T38","span":{"begin":267,"end":271},"obj":"CHEBI:46195"}],"text":"Acetaminophen (APAP) overdose is the most frequent cause of drug-induced liver damage. Magnolia officinalis is a traditional hepatoprotective Chinese medicine and Honokiol (HO) is the major active constituent. The present study was to investigate the effect of HO on APAP-induced hepatotoxicity and related mechanisms."}