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GoldHamster

Id Subject Object Predicate Lexical cue
T1 11-19 C056165 denotes Apocynin
T2 11-19 CHEBI:2781 denotes Apocynin
T3 11-19 C056165 denotes Apocynin
T6 29-56 D015427 denotes Ischemia-Reperfusion Injury
T7 29-56 D015427 denotes Ischemia-Reperfusion Injury
T12 60-64 10118 denotes Rats
T13 60-64 10116 denotes Rats
T14 60-64 D051381 denotes Rats
T15 77-85 D007511 denotes Ischemia
T16 77-85 D007511 denotes Ischemia
T17 166-187 D009203 denotes myocardial infarction
T18 166-187 D009203 denotes myocardial infarction
T21 277-296 D045506 denotes therapeutic effects
T22 277-296 D045506 denotes therapeutic effects
T23 300-308 C056165 denotes apocynin
T24 300-308 CHEBI:2781 denotes apocynin
T25 300-308 C056165 denotes apocynin
T26 317-322 UBERON:0002107 denotes liver
T28 358-361 PR:P63003-1 denotes rat
T29 358-361 PR:Q2G0B1 denotes rat
T30 358-361 PR:Q8VHJ4 denotes rat
T27 358-361 10116 denotes rat
T31 358-361 D051381 denotes rat
T32 389-393 10118 denotes rats
T33 389-393 10116 denotes rats
T34 389-393 D051381 denotes rats
T35 469-473 C005703 denotes sham
T36 469-473 C005703 denotes sham
T37 469-473 CHEBI:45615 denotes sham
T38 548-552 10118 denotes rats
T39 548-552 10116 denotes rats
T40 548-552 D051381 denotes rats
T41 618-626 D007511 denotes ischemia
T42 618-626 D007511 denotes ischemia
T43 674-678 10118 denotes rats
T44 674-678 10116 denotes rats
T45 674-678 D051381 denotes rats
T46 719-725 UBERON:0000479 denotes tissue
T47 736-744 D016877 denotes oxidants
T48 736-744 CHEBI:63248 denotes oxidants
T49 736-744 D016877 denotes oxidants
T50 749-761 CHEBI:22586 denotes antioxidants
T51 749-761 D000975 denotes antioxidants
T52 749-761 D000975 denotes antioxidants
T53 763-771 P44390 denotes catalase
T54 763-771 Q9S3V0 denotes catalase
T55 763-771 P0A323 denotes catalase
T56 763-771 P0A325 denotes catalase
T57 763-771 P45737 denotes catalase
T58 763-771 Q5RF10 denotes catalase
T59 763-771 PR:000005061 denotes catalase
T60 763-771 Q8CPD0 denotes catalase
T61 763-771 P55311 denotes catalase
T62 763-771 Q9PWF7 denotes catalase
T63 763-771 Q59296 denotes catalase
T64 763-771 O93662 denotes catalase
T65 763-771 Q7MFM6 denotes catalase
T66 763-771 Q9ZN99 denotes catalase
T68 763-771 Q59714 denotes catalase
T69 763-771 Q49XC1 denotes catalase
T70 763-771 Q9KW19 denotes catalase
T71 763-771 P30266 denotes catalase
T72 763-771 Q5HG86 denotes catalase
T73 763-771 Q2I6W4 denotes catalase
T74 763-771 Q64405 denotes catalase
T75 763-771 O68146 denotes catalase
T76 763-771 Q59635 denotes catalase
T77 763-771 O62839 denotes catalase
T78 763-771 P0A327 denotes catalase
T79 763-771 P77872 denotes catalase
T80 763-771 P25890 denotes catalase
T81 763-771 P0A326 denotes catalase
T82 763-771 Q8X1P0 denotes catalase
T83 763-771 Q2FH99 denotes catalase
T84 763-771 P55313 denotes catalase
T85 763-771 Q7A5T2 denotes catalase
T86 763-771 Q926X0 denotes catalase
T87 763-771 Q9Z598 denotes catalase
T88 763-771 Q59602 denotes catalase
T89 763-771 Q9M5L6 denotes catalase
T90 763-771 Q59337 denotes catalase
T91 763-771 Q27710 denotes catalase
T92 763-771 Q2PUJ9 denotes catalase
T93 763-771 Q6GH72 denotes catalase
T94 763-771 Q8NWV5 denotes catalase
T95 763-771 P55306 denotes catalase
T96 763-771 P29422 denotes catalase
T97 763-771 P55310 denotes catalase
T98 763-771 P00432 denotes catalase
T99 763-771 P46206 denotes catalase
T100 763-771 O52762 denotes catalase
T101 763-771 P04040 denotes catalase
T102 763-771 Q87JE8 denotes catalase
T103 763-771 P81138 denotes catalase
T104 763-771 Q8FWU0 denotes catalase
T105 763-771 Q8KHV6 denotes catalase
T106 763-771 P32290 denotes catalase
T107 763-771 P45739 denotes catalase
T108 763-771 Q8Y3P9 denotes catalase
T109 763-771 P24168 denotes catalase
T110 763-771 Q9ZKX5 denotes catalase
T111 763-771 Q4L643 denotes catalase
T112 763-771 P90682 denotes catalase
T113 763-771 P04762 denotes catalase
T114 763-771 Q9L4S1 denotes catalase
T115 763-771 P30265 denotes catalase
T116 763-771 P07145 denotes catalase
T117 763-771 O24339 denotes catalase
T118 763-771 Q5HPK8 denotes catalase
T119 763-771 Q2FYU7 denotes catalase
T120 763-771 Q6G9M4 denotes catalase
T121 763-771 P11934 denotes catalase
T122 763-771 P0A324 denotes catalase
T123 763-771 Q9KRQ1 denotes catalase
T124 763-771 Q9PT92 denotes catalase
T125 763-771 P17336 denotes catalase
T126 763-771 P42321 denotes catalase
T127 763-771 P24270 denotes catalase
T128 763-771 Q8D452 denotes catalase
T129 763-771 Q9AXH0 denotes catalase
T130 763-771 O97492 denotes catalase
T132 763-771 Q99UE2 denotes catalase
T133 763-771 Q2YXT2 denotes catalase
T67 763-771 D002374 denotes catalase
T131 763-771 CHEBI:3463 denotes catalase
T137 773-788 1657018 denotes malondialdehyde
T134 773-788 CHEBI:566274 denotes malondialdehyde
T135 773-788 D008315 denotes malondialdehyde
T136 773-788 D008315 denotes malondialdehyde
T139 790-805 1600930 denotes myeloperoxidase
T138 790-805 PR:000010543 denotes myeloperoxidase
T141 790-805 P11247 denotes myeloperoxidase
T142 790-805 P05164 denotes myeloperoxidase
T140 790-805 D009195 denotes myeloperoxidase
T144 828-831 PR:P61851 denotes SOD
T143 828-831 GO:0004784 denotes SOD
T149 844-855 4890 denotes glutathione
T145 844-855 D005978 denotes glutathione
T146 844-855 D005978 denotes glutathione
T147 844-855 CHEBI:11107 denotes glutathione
T148 844-855 CHEBI:11094 denotes glutathione
T150 844-855 CHEBI:57925 denotes glutathione
T151 844-855 CHEBI:16856 denotes glutathione
T153 880-883 PR:P61851 denotes SOD
T152 880-883 GO:0004784 denotes SOD
T154 926-930 C005703 denotes sham
T155 926-930 C005703 denotes sham
T156 926-930 CHEBI:45615 denotes sham
T158 995-998 PR:P61851 denotes SOD
T157 995-998 GO:0004784 denotes SOD
T159 1046-1061 PR:000010543 denotes myeloperoxidase
T162 1046-1061 P11247 denotes myeloperoxidase
T163 1046-1061 P05164 denotes myeloperoxidase
T160 1046-1061 1600930 denotes myeloperoxidase
T161 1046-1061 D009195 denotes myeloperoxidase
T164 1096-1100 C005703 denotes sham
T165 1096-1100 C005703 denotes sham
T166 1096-1100 CHEBI:45615 denotes sham
T167 1183-1189 UBERON:0001969 denotes plasma
T172 1196-1207 4890 denotes glutathione
T168 1196-1207 D005978 denotes glutathione
T169 1196-1207 D005978 denotes glutathione
T170 1196-1207 CHEBI:11107 denotes glutathione
T171 1196-1207 CHEBI:11094 denotes glutathione
T173 1196-1207 CHEBI:57925 denotes glutathione
T174 1196-1207 CHEBI:16856 denotes glutathione
T175 1209-1217 P44390 denotes catalase
T176 1209-1217 Q9S3V0 denotes catalase
T177 1209-1217 P0A323 denotes catalase
T178 1209-1217 P0A325 denotes catalase
T179 1209-1217 P45737 denotes catalase
T180 1209-1217 Q5RF10 denotes catalase
T181 1209-1217 PR:000005061 denotes catalase
T182 1209-1217 Q8CPD0 denotes catalase
T183 1209-1217 P55311 denotes catalase
T184 1209-1217 Q9PWF7 denotes catalase
T185 1209-1217 Q59296 denotes catalase
T186 1209-1217 O93662 denotes catalase
T187 1209-1217 Q7MFM6 denotes catalase
T188 1209-1217 Q9ZN99 denotes catalase
T190 1209-1217 Q59714 denotes catalase
T191 1209-1217 Q49XC1 denotes catalase
T192 1209-1217 Q9KW19 denotes catalase
T193 1209-1217 P30266 denotes catalase
T194 1209-1217 Q5HG86 denotes catalase
T195 1209-1217 Q2I6W4 denotes catalase
T196 1209-1217 Q64405 denotes catalase
T197 1209-1217 O68146 denotes catalase
T198 1209-1217 Q59635 denotes catalase
T199 1209-1217 O62839 denotes catalase
T200 1209-1217 P0A327 denotes catalase
T201 1209-1217 P77872 denotes catalase
T202 1209-1217 P25890 denotes catalase
T203 1209-1217 P0A326 denotes catalase
T204 1209-1217 Q8X1P0 denotes catalase
T205 1209-1217 Q2FH99 denotes catalase
T206 1209-1217 P55313 denotes catalase
T207 1209-1217 Q7A5T2 denotes catalase
T208 1209-1217 Q926X0 denotes catalase
T209 1209-1217 Q9Z598 denotes catalase
T210 1209-1217 Q59602 denotes catalase
T211 1209-1217 Q9M5L6 denotes catalase
T212 1209-1217 Q59337 denotes catalase
T213 1209-1217 Q27710 denotes catalase
T214 1209-1217 Q2PUJ9 denotes catalase
T215 1209-1217 Q6GH72 denotes catalase
T216 1209-1217 Q8NWV5 denotes catalase
T217 1209-1217 P55306 denotes catalase
T218 1209-1217 P29422 denotes catalase
T219 1209-1217 P55310 denotes catalase
T220 1209-1217 P00432 denotes catalase
T221 1209-1217 P46206 denotes catalase
T222 1209-1217 O52762 denotes catalase
T223 1209-1217 P04040 denotes catalase
T224 1209-1217 Q87JE8 denotes catalase
T225 1209-1217 P81138 denotes catalase
T226 1209-1217 Q8FWU0 denotes catalase
T227 1209-1217 Q8KHV6 denotes catalase
T228 1209-1217 P32290 denotes catalase
T229 1209-1217 P45739 denotes catalase
T230 1209-1217 Q8Y3P9 denotes catalase
T231 1209-1217 P24168 denotes catalase
T232 1209-1217 Q9ZKX5 denotes catalase
T233 1209-1217 Q4L643 denotes catalase
T234 1209-1217 P90682 denotes catalase
T235 1209-1217 P04762 denotes catalase
T236 1209-1217 Q9L4S1 denotes catalase
T237 1209-1217 P30265 denotes catalase
T238 1209-1217 P07145 denotes catalase
T239 1209-1217 O24339 denotes catalase
T240 1209-1217 Q5HPK8 denotes catalase
T241 1209-1217 Q2FYU7 denotes catalase
T242 1209-1217 Q6G9M4 denotes catalase
T243 1209-1217 P11934 denotes catalase
T244 1209-1217 P0A324 denotes catalase
T245 1209-1217 Q9KRQ1 denotes catalase
T246 1209-1217 Q9PT92 denotes catalase
T247 1209-1217 P17336 denotes catalase
T248 1209-1217 P42321 denotes catalase
T249 1209-1217 P24270 denotes catalase
T250 1209-1217 Q8D452 denotes catalase
T251 1209-1217 Q9AXH0 denotes catalase
T252 1209-1217 O97492 denotes catalase
T254 1209-1217 Q99UE2 denotes catalase
T255 1209-1217 Q2YXT2 denotes catalase
T189 1209-1217 D002374 denotes catalase
T253 1209-1217 CHEBI:3463 denotes catalase
T259 1223-1238 1657018 denotes malondialdehyde
T256 1223-1238 CHEBI:566274 denotes malondialdehyde
T257 1223-1238 D008315 denotes malondialdehyde
T258 1223-1238 D008315 denotes malondialdehyde
T260 1292-1296 10118 denotes rats
T261 1292-1296 10116 denotes rats
T262 1292-1296 D051381 denotes rats
T263 1386-1391 UBERON:0002107 denotes liver
T264 1488-1499 CHEBI:22586 denotes antioxidant
T266 1513-1516 PR:P63003-1 denotes rat
T267 1513-1516 PR:Q2G0B1 denotes rat
T268 1513-1516 PR:Q8VHJ4 denotes rat
T265 1513-1516 10116 denotes rat
T269 1513-1516 D051381 denotes rat
T270 1526-1531 UBERON:0002107 denotes liver

PubMed_Structured_Abstracts

Id Subject Object Predicate Lexical cue
T1 77-368 OBJECTIVE denotes Ischemia-reperfusion (IR) injury is associated with various clinical conditions, such as myocardial infarction, shock, and surgery under vascular occlusion. We aimed to investigate the protective and therapeutic effects of apocynin (AP) on liver injury induced by IR in an in vivo rat model.
T2 378-857 METHODS denotes Thirty-two rats were randomly divided into 4 experimental groups with n = 8 in each group: sham, IR, AP, and IR + AP. AP (20 mg/kg) was intraperitoneally administered to rats in the AP and IR + AP groups for 30 minutes before 60 minutes of ischemia and followed by 60 minutes of reperfusion. All rats were killed on the same day to evaluate tissue levels of oxidants and antioxidants (catalase, malondialdehyde, myeloperoxidase, superoxidedismutase (SOD), and total glutathione).
T3 867-1297 RESULTS denotes IR decreased SOD levels in IR group when compared with the sham group. AP supplementation to IR group significantly ameliorated SOD levels (P < .05). Also, IR caused elevation of myeloperoxidase production when compared with the sham group, whereas AP treatment prevented these hazardous effects (P < .05). However, plasma total glutathione, catalase, and malondialdehyde levels did not differ between the AP + IR and the IR rats.
T4 1310-1535 CONCLUSIONS denotes The main finding of the present study was that AP may be protective against liver IR injury. Our results suggested that AP pretreatment suppressed oxidative stress and increased antioxidant levels in an rat model of liver IR.

Goldhamster2_Cellosaurus

Id Subject Object Predicate Lexical cue
T1 99-101 CVCL_ZD54|Transformed_cell_line|Homo sapiens denotes IR
T2 234-236 CVCL_5M23|Cancer_cell_line|Mesocricetus auratus denotes We
T3 310-312 CVCL_E457|Transformed_cell_line|Homo sapiens denotes AP
T4 341-343 CVCL_ZD54|Transformed_cell_line|Homo sapiens denotes IR
T5 347-349 CVCL_8754|Cancer_cell_line|Homo sapiens denotes an
T6 347-349 CVCL_H241|Cancer_cell_line|Homo sapiens denotes an
T7 448-453 CVCL_D463|Transformed_cell_line|Mus musculus denotes n = 8
T8 448-453 CVCL_IZ69|Spontaneously_immortalized_cell_line|Homo sapiens denotes n = 8
T9 475-477 CVCL_ZD54|Transformed_cell_line|Homo sapiens denotes IR
T10 479-481 CVCL_E457|Transformed_cell_line|Homo sapiens denotes AP
T11 487-489 CVCL_ZD54|Transformed_cell_line|Homo sapiens denotes IR
T12 492-494 CVCL_E457|Transformed_cell_line|Homo sapiens denotes AP
T13 496-498 CVCL_E457|Transformed_cell_line|Homo sapiens denotes AP
T14 500-502 CVCL_J923|Hybridoma|Mus musculus denotes 20
T15 560-562 CVCL_E457|Transformed_cell_line|Homo sapiens denotes AP
T16 567-569 CVCL_ZD54|Transformed_cell_line|Homo sapiens denotes IR
T17 572-574 CVCL_E457|Transformed_cell_line|Homo sapiens denotes AP
T18 586-588 CVCL_J925|Hybridoma|Mus musculus denotes 30
T19 604-606 CVCL_C917|Induced_pluripotent_stem_cell|Homo sapiens denotes 60
T20 643-645 CVCL_C917|Induced_pluripotent_stem_cell|Homo sapiens denotes 60
T21 867-869 CVCL_ZD54|Transformed_cell_line|Homo sapiens denotes IR
T22 894-896 CVCL_ZD54|Transformed_cell_line|Homo sapiens denotes IR
T23 938-940 CVCL_E457|Transformed_cell_line|Homo sapiens denotes AP
T24 960-962 CVCL_ZD54|Transformed_cell_line|Homo sapiens denotes IR
T25 1023-1025 CVCL_ZD54|Transformed_cell_line|Homo sapiens denotes IR
T26 1116-1118 CVCL_E457|Transformed_cell_line|Homo sapiens denotes AP
T27 1273-1275 CVCL_E457|Transformed_cell_line|Homo sapiens denotes AP
T28 1278-1280 CVCL_ZD54|Transformed_cell_line|Homo sapiens denotes IR
T29 1289-1291 CVCL_ZD54|Transformed_cell_line|Homo sapiens denotes IR
T30 1357-1359 CVCL_E457|Transformed_cell_line|Homo sapiens denotes AP
T31 1360-1363 CVCL_E773|Transformed_cell_line|Homo sapiens denotes may
T32 1392-1394 CVCL_ZD54|Transformed_cell_line|Homo sapiens denotes IR
T33 1430-1432 CVCL_E457|Transformed_cell_line|Homo sapiens denotes AP
T34 1510-1512 CVCL_8754|Cancer_cell_line|Homo sapiens denotes an
T35 1510-1512 CVCL_H241|Cancer_cell_line|Homo sapiens denotes an
T36 1532-1534 CVCL_ZD54|Transformed_cell_line|Homo sapiens denotes IR