PubMed:30593372
Annnotations
GoldHamster
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 8-24 | D017934 | denotes | deltacoronavirus |
T4 | 33-37 | CVCL_5601 | denotes | TLR3 |
T2 | 33-37 | PR:000001154 | denotes | TLR3 |
T3 | 33-37 | PR:Q99MB1 | denotes | TLR3 |
T5 | 33-37 | PR:O15455 | denotes | TLR3 |
T6 | 39-44 | D018664 | denotes | IL-12 |
T8 | 39-44 | D018664 | denotes | IL-12 |
T7 | 39-44 | GO:0005143 | denotes | IL-12 |
T15 | 63-66 | CVCL_2693 | denotes | PKR |
T9 | 63-66 | Q03963 | denotes | PKR |
T10 | 63-66 | PR:000006959 | denotes | PKR |
T11 | 63-66 | P19525 | denotes | PKR |
T12 | 63-66 | PR:Q03963 | denotes | PKR |
T13 | 63-66 | PR:P19525 | denotes | PKR |
T14 | 63-66 | Q63184 | denotes | PKR |
T18 | 67-71 | SO:0000234 | denotes | mRNA |
T16 | 67-71 | D012333 | denotes | mRNA |
T17 | 67-71 | CHEBI:33699 | denotes | mRNA |
T19 | 103-110 | CVCL_E012 | denotes | patches |
T20 | 128-144 | D017934 | denotes | deltacoronavirus |
T21 | 175-180 | D013552 | denotes | swine |
T22 | 175-180 | 9823 | denotes | swine |
T23 | 198-209 | D017934 | denotes | coronavirus |
T24 | 229-237 | D003967 | denotes | diarrhea |
T25 | 229-237 | D003967 | denotes | diarrhea |
T27 | 299-302 | P30941 | denotes | pig |
T26 | 299-302 | 9823 | denotes | pig |
T28 | 360-368 | D014612 | denotes | vaccines |
T29 | 360-368 | D014612 | denotes | vaccines |
T30 | 399-411 | GO:0009405 | denotes | pathogenesis |
T31 | 421-430 | D007239 | denotes | infection |
T32 | 421-430 | D007239 | denotes | infection |
T33 | 448-455 | 32644 | denotes | unknown |
T34 | 562-565 | PR:000011410 | denotes | CHN |
T35 | 562-565 | PR:P30337 | denotes | CHN |
T36 | 562-565 | PR:Q92570 | denotes | CHN |
T37 | 562-565 | PR:Q7YU81 | denotes | CHN |
T38 | 562-565 | PR:P15882 | denotes | CHN |
T39 | 562-565 | PR:000005442 | denotes | CHN |
T40 | 562-565 | CHEBI:18407 | denotes | CHN |
T41 | 616-624 | D003967 | denotes | diarrhea |
T42 | 616-624 | D003967 | denotes | diarrhea |
T44 | 626-635 | D012328 | denotes | Virus RNA |
T47 | 632-635 | GO:0005562 | denotes | RNA |
T48 | 632-635 | SO:0000356 | denotes | RNA |
T45 | 632-635 | CHEBI:33697 | denotes | RNA |
T46 | 632-635 | D012313 | denotes | RNA |
T50 | 736-751 | UBERON:0002108 | denotes | small intestine |
T52 | 777-784 | D000941 | denotes | antigen |
T53 | 777-784 | CHEBI:59132 | denotes | antigen |
T54 | 777-784 | D000941 | denotes | antigen |
T57 | 905-909 | SO:0000234 | denotes | mRNA |
T55 | 905-909 | D012333 | denotes | mRNA |
T56 | 905-909 | CHEBI:33699 | denotes | mRNA |
T58 | 924-928 | PR:000001154 | denotes | TLR3 |
T59 | 924-928 | PR:Q99MB1 | denotes | TLR3 |
T61 | 924-928 | PR:O15455 | denotes | TLR3 |
T60 | 924-928 | CVCL_5601 | denotes | TLR3 |
T62 | 930-935 | D018664 | denotes | IL-12 |
T64 | 930-935 | D018664 | denotes | IL-12 |
T63 | 930-935 | GO:0005143 | denotes | IL-12 |
T65 | 955-958 | Q03963 | denotes | PKR |
T66 | 955-958 | PR:000006959 | denotes | PKR |
T67 | 955-958 | P19525 | denotes | PKR |
T68 | 955-958 | PR:Q03963 | denotes | PKR |
T69 | 955-958 | PR:P19525 | denotes | PKR |
T70 | 955-958 | Q63184 | denotes | PKR |
T71 | 955-958 | CVCL_2693 | denotes | PKR |
T72 | 1043-1050 | CVCL_E012 | denotes | patches |
T86 | 1051-1057 | D020152 | denotes | at 3 d |
T87 | 1088-1095 | CVCL_E012 | denotes | patches |
T88 | 1207-1211 | SO:0000704 | denotes | gene |
T89 | 1207-1222 | GO:0010467 | denotes | gene expression |
T90 | 1311-1320 | D007239 | denotes | infection |
T91 | 1311-1320 | D007239 | denotes | infection |
PubMed_ArguminSci
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 120-312 | DRI_Challenge | denotes | Porcine deltacoronavirus (PDCoV) is a newly identified swine enteropathogenic coronavirus that causes watery diarrhea in piglets and results in significant economic losses to the pig industry. |
T2 | 313-379 | DRI_Background | denotes | Currently there are no effective treatments or vaccines for PDCoV. |
T3 | 380-456 | DRI_Background | denotes | In particular, the pathogenesis of PDCoV infection is still largely unknown. |
T4 | 457-555 | DRI_Outcome | denotes | In this study, we reported that inoculating conventional weaned piglets with 1 × 109 TCID50 of the |
T5 | 574-625 | DRI_Outcome | denotes | strain by oral feeding could cause severe diarrhea. |
T6 | 626-699 | DRI_Background | denotes | Virus RNA was detected in rectal swabs from 1 to 7 days post inoculation. |
T7 | 700-863 | DRI_Outcome | denotes | In addition, microscopic lesions in small intestine were observed, and viral antigen also detected in the small intestines with PDCoV immunohistochemical staining. |
T8 | 864-1153 | DRI_Outcome | denotes | Importantly, PDCoV significantly induced mRNA expression of TLR3, IL-12, IFN-α, IFN-β, and PKR, the genes involved in modulation of the host immune responses, in infected Peyer's patches at 3 d.p.i., indicating that Peyer's patches play an important role in PDCoV immune responses in vivo. |
T9 | 1154-1321 | DRI_Outcome | denotes | Collectively, our findings suggest that the observed gene expression profile might help explain immunological and pathological changes associated with PDCoV infection. |
Goldhamster2_Cellosaurus
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 33-37 | CVCL_5601|Conditionally_immortalized_cell_line|Mus musculus | denotes | TLR3 |
T2 | 63-66 | CVCL_2693|Spontaneously_immortalized_cell_line|Sus scrofa | denotes | PKR |
T3 | 103-110 | CVCL_E012|Induced_pluripotent_stem_cell|Homo sapiens | denotes | patches |
T4 | 156-157 | CVCL_6479|Finite_cell_line|Mus musculus | denotes | a |
T5 | 472-474 | CVCL_5M23|Cancer_cell_line|Mesocricetus auratus | denotes | we |
T6 | 924-928 | CVCL_5601|Conditionally_immortalized_cell_line|Mus musculus | denotes | TLR3 |
T7 | 955-958 | CVCL_2693|Spontaneously_immortalized_cell_line|Sus scrofa | denotes | PKR |
T8 | 1043-1050 | CVCL_E012|Induced_pluripotent_stem_cell|Homo sapiens | denotes | patches |
T9 | 1051-1055 | CVCL_0146|Cancer_cell_line|Rattus norvegicus | denotes | at 3 |
T10 | 1051-1055 | CVCL_VR89|Cancer_cell_line|Mus musculus | denotes | at 3 |
T11 | 1088-1095 | CVCL_E012|Induced_pluripotent_stem_cell|Homo sapiens | denotes | patches |
T12 | 1101-1103 | CVCL_8754|Cancer_cell_line|Homo sapiens | denotes | an |
T13 | 1101-1103 | CVCL_H241|Cancer_cell_line|Homo sapiens | denotes | an |
T14 | 1281-1288 | CVCL_0238|Cancer_cell_line|Homo sapiens | denotes | changes |