PubMed:3056614
Annnotations
GlyCosmos6-Glycan-Motif-Image
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 841-851 | Glycan_Motif | denotes | Tn antigen | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G57321FI |
| T2 | 977-988 | Glycan_Motif | denotes | (T) antigen | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00031MO |
| T3 | 1099-1110 | Glycan_Motif | denotes | Tn antigens | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G57321FI |
| T4 | 1403-1413 | Glycan_Motif | denotes | Tn antigen | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G57321FI |
| T5 | 1522-1532 | Glycan_Motif | denotes | Tn antigen | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G57321FI |
sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| TextSentencer_T1 | 0-197 | Sentence | denotes | Blood group Tn-active macromolecules from human carcinomas and erythrocytes: characterization of and specific reactivity with mono- and poly-clonal anti-Tn antibodies induced by various immunogens. |
| TextSentencer_T2 | 198-462 | Sentence | denotes | In contrast to healthy and noncarcinoma-diseased tissues, greater than 80% of all carcinomas (CAs) tested express immunoreactive O-(2-acetamido-2-deoxy-alpha-D-galacto-pyranosyl)-(1----3)-serine/threon ine [alpha-D-GalpNAc-(1----3)-Ser/Thr] in their glycoproteins. |
| TextSentencer_T3 | 463-595 | Sentence | denotes | CA cells shed, into the tumor's environment, Tn, which is involved in cancer pathogenesis as adhesion molecule and as autoimmunogen. |
| TextSentencer_T4 | 596-688 | Sentence | denotes | An increase in density of Tn on primary CA frequently parallels augmented CA aggressiveness. |
| TextSentencer_T5 | 689-989 | Sentence | denotes | Tn-Active glycoproteins of culture-grown human breast CA DU 4475 cells were isolated from cytoplasm and from spent growth medium, and erythrocyte (RBC) Tn antigen was prepared by (1----3)-beta-D-galactosidase treatment of isolated human O RBC MN glycoprotein-derived Thomsen-Friedenreich (T) antigen. |
| TextSentencer_T6 | 990-1111 | Sentence | denotes | Immunochemical, serological, physical, and chemical analyses showed close resemblance of CA- and RBC-derived Tn antigens. |
| TextSentencer_T7 | 1112-1287 | Sentence | denotes | The preponderant carbohydrate in both Tn glycoproteins is the alpha-D-GalpNAc residue, and the antigens have a qualitatively and quantitatively similar amino acid composition. |
| TextSentencer_T8 | 1288-1479 | Sentence | denotes | Highly specific rodent monoclonal (Mo) anti-Tn antibodies (Abs) were elicited with Tn RBC and normal O RBC-derived Tn antigen, and compared with CA-anti-Tn MoAbs unwittingly evoked by others. |
| TextSentencer_T9 | 1480-1562 | Sentence | denotes | A sensitive enzyme immunoassay (EIA) with Tn antigen as solid phase was developed. |
| TextSentencer_T10 | 1563-1813 | Sentence | denotes | In this system, highly purified, "naturally occurring" anti-Tn antibodies, which all humans possess, were more sensitive in quantitating breast CA Tn structures than the anti-Tn MoAbs induced by Tn RBCs, and by RBC- and CA-derived Tn-active antigens. |
| TextSentencer_T11 | 1814-1878 | Sentence | denotes | The sensitivity of anti-Tn MoAbs was higher in detecting RBC-Tn. |
| T1 | 0-197 | Sentence | denotes | Blood group Tn-active macromolecules from human carcinomas and erythrocytes: characterization of and specific reactivity with mono- and poly-clonal anti-Tn antibodies induced by various immunogens. |
| T2 | 198-462 | Sentence | denotes | In contrast to healthy and noncarcinoma-diseased tissues, greater than 80% of all carcinomas (CAs) tested express immunoreactive O-(2-acetamido-2-deoxy-alpha-D-galacto-pyranosyl)-(1----3)-serine/threon ine [alpha-D-GalpNAc-(1----3)-Ser/Thr] in their glycoproteins. |
| T3 | 463-595 | Sentence | denotes | CA cells shed, into the tumor's environment, Tn, which is involved in cancer pathogenesis as adhesion molecule and as autoimmunogen. |
| T4 | 596-688 | Sentence | denotes | An increase in density of Tn on primary CA frequently parallels augmented CA aggressiveness. |
| T5 | 689-989 | Sentence | denotes | Tn-Active glycoproteins of culture-grown human breast CA DU 4475 cells were isolated from cytoplasm and from spent growth medium, and erythrocyte (RBC) Tn antigen was prepared by (1----3)-beta-D-galactosidase treatment of isolated human O RBC MN glycoprotein-derived Thomsen-Friedenreich (T) antigen. |
| T6 | 990-1111 | Sentence | denotes | Immunochemical, serological, physical, and chemical analyses showed close resemblance of CA- and RBC-derived Tn antigens. |
| T7 | 1112-1287 | Sentence | denotes | The preponderant carbohydrate in both Tn glycoproteins is the alpha-D-GalpNAc residue, and the antigens have a qualitatively and quantitatively similar amino acid composition. |
| T8 | 1288-1479 | Sentence | denotes | Highly specific rodent monoclonal (Mo) anti-Tn antibodies (Abs) were elicited with Tn RBC and normal O RBC-derived Tn antigen, and compared with CA-anti-Tn MoAbs unwittingly evoked by others. |
| T9 | 1480-1562 | Sentence | denotes | A sensitive enzyme immunoassay (EIA) with Tn antigen as solid phase was developed. |
| T10 | 1563-1813 | Sentence | denotes | In this system, highly purified, "naturally occurring" anti-Tn antibodies, which all humans possess, were more sensitive in quantitating breast CA Tn structures than the anti-Tn MoAbs induced by Tn RBCs, and by RBC- and CA-derived Tn-active antigens. |
| T11 | 1814-1878 | Sentence | denotes | The sensitivity of anti-Tn MoAbs was higher in detecting RBC-Tn. |
GlyCosmos6-Glycan-Motif-Structure
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 841-851 | https://glytoucan.org/Structures/Glycans/G57321FI | denotes | Tn antigen |
| T2 | 977-988 | https://glytoucan.org/Structures/Glycans/G00031MO | denotes | (T) antigen |
| T3 | 1099-1110 | https://glytoucan.org/Structures/Glycans/G57321FI | denotes | Tn antigens |
| T4 | 1403-1413 | https://glytoucan.org/Structures/Glycans/G57321FI | denotes | Tn antigen |
| T5 | 1522-1532 | https://glytoucan.org/Structures/Glycans/G57321FI | denotes | Tn antigen |
Glycosmos6-GlycoEpitope
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 841-851 | http://www.glycoepitope.jp/epitopes/EP0021 | denotes | Tn antigen |
| T2 | 1403-1413 | http://www.glycoepitope.jp/epitopes/EP0021 | denotes | Tn antigen |
| T3 | 1522-1532 | http://www.glycoepitope.jp/epitopes/EP0021 | denotes | Tn antigen |
Glycosmos6-MAT
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-5 | http://purl.obolibrary.org/obo/MAT_0000083 | denotes | Blood |
| T2 | 0-5 | http://purl.obolibrary.org/obo/MAT_0000315 | denotes | Blood |
GlyCosmos15-Glycan
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 841-851 | Glycan | denotes | Tn antigen | https://api.glycosmos.org/wurcs2image/latest/png/binary/G57321FI |
| T2 | 977-988 | Glycan | denotes | (T) antigen | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00031MO |
| T3 | 1403-1413 | Glycan | denotes | Tn antigen | https://api.glycosmos.org/wurcs2image/latest/png/binary/G57321FI |
| T4 | 1522-1532 | Glycan | denotes | Tn antigen | https://api.glycosmos.org/wurcs2image/latest/png/binary/G57321FI |
Anatomy-MAT
| Id | Subject | Object | Predicate | Lexical cue | mat_id |
|---|---|---|---|---|---|
| T1 | 0-5 | Body_part | denotes | Blood | http://purl.obolibrary.org/obo/MAT_0000083|http://purl.obolibrary.org/obo/MAT_0000315 |
HP-phenotype
| Id | Subject | Object | Predicate | Lexical cue | hp_id |
|---|---|---|---|---|---|
| T1 | 48-58 | Phenotype | denotes | carcinomas | HP:0030731 |
| T2 | 280-290 | Phenotype | denotes | carcinomas | HP:0030731 |
| T3 | 292-295 | Phenotype | denotes | CAs | HP:0030731 |
| T4 | 533-539 | Phenotype | denotes | cancer | HP:0002664 |
| T5 | 673-687 | Phenotype | denotes | aggressiveness | HP:0000718 |
mondo_disease
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T1 | 48-58 | Disease | denotes | carcinomas | http://purl.obolibrary.org/obo/MONDO_0004993 |
| T2 | 280-290 | Disease | denotes | carcinomas | http://purl.obolibrary.org/obo/MONDO_0004993 |
| T3 | 292-295 | Disease | denotes | CAs | http://purl.obolibrary.org/obo/MONDO_0004993 |
| T4 | 533-539 | Disease | denotes | cancer | http://purl.obolibrary.org/obo/MONDO_0004992 |
Glycan-GlyCosmos
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 841-851 | Glycan | denotes | Tn antigen | https://api.glycosmos.org/wurcs2image/latest/png/binary/G57321FI |
| T2 | 1403-1413 | Glycan | denotes | Tn antigen | https://api.glycosmos.org/wurcs2image/latest/png/binary/G57321FI |
| T3 | 1522-1532 | Glycan | denotes | Tn antigen | https://api.glycosmos.org/wurcs2image/latest/png/binary/G57321FI |
GlyCosmos15-HP
| Id | Subject | Object | Predicate | Lexical cue | hp_id |
|---|---|---|---|---|---|
| T1 | 48-58 | Phenotype | denotes | carcinomas | HP:0030731 |
| T2 | 280-290 | Phenotype | denotes | carcinomas | HP:0030731 |
| T3 | 292-295 | Phenotype | denotes | CAs | HP:0030731 |
| T4 | 533-539 | Phenotype | denotes | cancer | HP:0002664 |
| T5 | 673-687 | Phenotype | denotes | aggressiveness | HP:0000718 |
GlyCosmos15-CL
| Id | Subject | Object | Predicate | Lexical cue | cl_id |
|---|---|---|---|---|---|
| T1 | 63-75 | Cell | denotes | erythrocytes | http://purl.obolibrary.org/obo/CL:0000232 |
| T2 | 136-140 | Cell | denotes | poly | http://purl.obolibrary.org/obo/CL:0000096|http://purl.obolibrary.org/obo/CL:0000775 |
| T4 | 823-834 | Cell | denotes | erythrocyte | http://purl.obolibrary.org/obo/CL:0000232 |
GlyCosmos15-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 0-5 | Body_part | denotes | Blood | http://purl.obolibrary.org/obo/UBERON_0000178 |
| T2 | 63-75 | Body_part | denotes | erythrocytes | http://purl.obolibrary.org/obo/CL_0000232 |
| T3 | 736-742 | Body_part | denotes | breast | http://purl.obolibrary.org/obo/UBERON_0000310 |
| T4 | 779-788 | Body_part | denotes | cytoplasm | http://purl.obolibrary.org/obo/GO_0005737 |
| T5 | 823-834 | Body_part | denotes | erythrocyte | http://purl.obolibrary.org/obo/CL_0000232 |
| T6 | 1700-1706 | Body_part | denotes | breast | http://purl.obolibrary.org/obo/UBERON_0000310 |
GlyCosmos15-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T1 | 48-58 | Disease | denotes | carcinomas | MONDO:0004993 |
| T2 | 280-290 | Disease | denotes | carcinomas | MONDO:0004993 |
| T3 | 292-295 | Disease | denotes | CAs | MONDO:0004993 |
| T4 | 533-539 | Disease | denotes | cancer | MONDO:0004992 |
GlyCosmos15-Taxon
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 42-47 | Organism | denotes | human | 9606 |
| T2 | 730-735 | Organism | denotes | human | 9606 |
| T3 | 920-925 | Organism | denotes | human | 9606 |
GlyCosmos15-GlycoEpitope
| Id | Subject | Object | Predicate | Lexical cue | glycoepitope_id |
|---|---|---|---|---|---|
| T1 | 841-851 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | Tn antigen | http://www.glycoepitope.jp/epitopes/EP0021 |
| T2 | 1403-1413 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | Tn antigen | http://www.glycoepitope.jp/epitopes/EP0021 |
| T3 | 1522-1532 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | Tn antigen | http://www.glycoepitope.jp/epitopes/EP0021 |
GlyCosmos15-Sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-197 | Sentence | denotes | Blood group Tn-active macromolecules from human carcinomas and erythrocytes: characterization of and specific reactivity with mono- and poly-clonal anti-Tn antibodies induced by various immunogens. |
| T2 | 198-462 | Sentence | denotes | In contrast to healthy and noncarcinoma-diseased tissues, greater than 80% of all carcinomas (CAs) tested express immunoreactive O-(2-acetamido-2-deoxy-alpha-D-galacto-pyranosyl)-(1----3)-serine/threon ine [alpha-D-GalpNAc-(1----3)-Ser/Thr] in their glycoproteins. |
| T3 | 463-595 | Sentence | denotes | CA cells shed, into the tumor's environment, Tn, which is involved in cancer pathogenesis as adhesion molecule and as autoimmunogen. |
| T4 | 596-688 | Sentence | denotes | An increase in density of Tn on primary CA frequently parallels augmented CA aggressiveness. |
| T5 | 689-989 | Sentence | denotes | Tn-Active glycoproteins of culture-grown human breast CA DU 4475 cells were isolated from cytoplasm and from spent growth medium, and erythrocyte (RBC) Tn antigen was prepared by (1----3)-beta-D-galactosidase treatment of isolated human O RBC MN glycoprotein-derived Thomsen-Friedenreich (T) antigen. |
| T6 | 990-1111 | Sentence | denotes | Immunochemical, serological, physical, and chemical analyses showed close resemblance of CA- and RBC-derived Tn antigens. |
| T7 | 1112-1287 | Sentence | denotes | The preponderant carbohydrate in both Tn glycoproteins is the alpha-D-GalpNAc residue, and the antigens have a qualitatively and quantitatively similar amino acid composition. |
| T8 | 1288-1479 | Sentence | denotes | Highly specific rodent monoclonal (Mo) anti-Tn antibodies (Abs) were elicited with Tn RBC and normal O RBC-derived Tn antigen, and compared with CA-anti-Tn MoAbs unwittingly evoked by others. |
| T9 | 1480-1562 | Sentence | denotes | A sensitive enzyme immunoassay (EIA) with Tn antigen as solid phase was developed. |
| T10 | 1563-1813 | Sentence | denotes | In this system, highly purified, "naturally occurring" anti-Tn antibodies, which all humans possess, were more sensitive in quantitating breast CA Tn structures than the anti-Tn MoAbs induced by Tn RBCs, and by RBC- and CA-derived Tn-active antigens. |
| T11 | 1814-1878 | Sentence | denotes | The sensitivity of anti-Tn MoAbs was higher in detecting RBC-Tn. |
GlyCosmos15-FMA
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 0-5 | Body_part | denotes | Blood | FMA:9670 |
| T2 | 63-75 | Body_part | denotes | erythrocytes | FMA:62845 |
| T3 | 247-254 | Body_part | denotes | tissues | FMA:9637 |
| T4 | 736-742 | Body_part | denotes | breast | FMA:9601 |
| T5 | 779-788 | Body_part | denotes | cytoplasm | FMA:66835 |
| T6 | 823-834 | Body_part | denotes | erythrocyte | FMA:62845 |
| T7 | 1700-1706 | Body_part | denotes | breast | FMA:9601 |
GlyCosmos15-MAT
| Id | Subject | Object | Predicate | Lexical cue | mat_id |
|---|---|---|---|---|---|
| T1 | 0-5 | Body_part | denotes | Blood | http://purl.obolibrary.org/obo/MAT_0000315 |
NCBITAXON
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 42-47 | OrganismTaxon | denotes | human | 9606 |
| T2 | 730-735 | OrganismTaxon | denotes | human | 9606 |
| T3 | 920-925 | OrganismTaxon | denotes | human | 9606 |
GlyCosmos-GlycoEpitope
| Id | Subject | Object | Predicate | Lexical cue | glycoepitope_id |
|---|---|---|---|---|---|
| T1 | 841-851 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | Tn antigen | http://www.glycoepitope.jp/epitopes/EP0021 |
| T2 | 1403-1413 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | Tn antigen | http://www.glycoepitope.jp/epitopes/EP0021 |
| T3 | 1522-1532 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | Tn antigen | http://www.glycoepitope.jp/epitopes/EP0021 |
Anatomy-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 0-5 | Body_part | denotes | Blood | http://purl.obolibrary.org/obo/UBERON_0000178 |
| T2 | 63-75 | Body_part | denotes | erythrocytes | http://purl.obolibrary.org/obo/CL_0000232 |
| T3 | 736-742 | Body_part | denotes | breast | http://purl.obolibrary.org/obo/UBERON_0000310 |
| T4 | 779-788 | Body_part | denotes | cytoplasm | http://purl.obolibrary.org/obo/GO_0005737 |
| T5 | 823-834 | Body_part | denotes | erythrocyte | http://purl.obolibrary.org/obo/CL_0000232 |
| T6 | 1700-1706 | Body_part | denotes | breast | http://purl.obolibrary.org/obo/UBERON_0000310 |
CL-cell
| Id | Subject | Object | Predicate | Lexical cue | cl_id |
|---|---|---|---|---|---|
| T1 | 63-75 | Cell | denotes | erythrocytes | http://purl.obolibrary.org/obo/CL:0000232 |
| T2 | 136-140 | Cell | denotes | poly | http://purl.obolibrary.org/obo/CL:0000096|http://purl.obolibrary.org/obo/CL:0000775 |
| T4 | 823-834 | Cell | denotes | erythrocyte | http://purl.obolibrary.org/obo/CL:0000232 |