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PubMed:30006512
Annnotations
ngly1-sample5
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 433-452 | chem:24139 | denotes | N-acetylglucosamine |
T2 | 1177-1196 | chem:24139 | denotes | N-acetylglucosamine |
T3 | 1437-1443 | chem:24139 | denotes | GlcNAc |
NGLY1-deficiency
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
PD-NGLY1-deficiency-B_T1 | 433-452 | chem:24139 | denotes | N-acetylglucosamine |
PD-NGLY1-deficiency-B_T2 | 765-785 | chem:24139 | denotes | N-acetyl glucosamine |
PD-NGLY1-deficiency-B_T3 | 1177-1196 | chem:24139 | denotes | N-acetylglucosamine |
PD-NGLY1-deficiency-B_T4 | 1437-1443 | chem:24139 | denotes | GlcNAc |
T1 | 433-452 | chem:24139 | denotes | N-acetylglucosamine |
T2 | 765-785 | chem:24139 | denotes | N-acetyl glucosamine |
T3 | 1177-1196 | chem:24139 | denotes | N-acetylglucosamine |
T4 | 1437-1443 | chem:24139 | denotes | GlcNAc |
Anatomy-MAT
Id | Subject | Object | Predicate | Lexical cue | mat_id |
---|---|---|---|---|---|
T1 | 99-102 | Body_part | denotes | gut | http://purl.obolibrary.org/obo/MAT_0000043 |
T2 | 636-639 | Body_part | denotes | gut | http://purl.obolibrary.org/obo/MAT_0000043 |
T3 | 1283-1286 | Body_part | denotes | gut | http://purl.obolibrary.org/obo/MAT_0000043 |
Glycan-GlyCosmos
Id | Subject | Object | Predicate | Lexical cue | image |
---|---|---|---|---|---|
T1 | 1415-1422 | Glycan | denotes | lactose | https://api.glycosmos.org/wurcs2image/latest/png/binary/G15541SE |
T2 | 1525-1532 | Glycan | denotes | lactose | https://api.glycosmos.org/wurcs2image/latest/png/binary/G15541SE |
GlyCosmos15-UBERON
Id | Subject | Object | Predicate | Lexical cue | uberon_id |
---|---|---|---|---|---|
T1 | 99-102 | Body_part | denotes | gut | http://purl.obolibrary.org/obo/UBERON_0001007|http://purl.obolibrary.org/obo/UBERON_0001555|http://purl.obolibrary.org/obo/UBERON_0004907 |
T4 | 160-164 | Body_part | denotes | milk | http://purl.obolibrary.org/obo/UBERON_0001913 |
T5 | 263-285 | Body_part | denotes | gastrointestinal tract | http://purl.obolibrary.org/obo/UBERON_0005409 |
T6 | 510-514 | Body_part | denotes | milk | http://purl.obolibrary.org/obo/UBERON_0001913 |
T7 | 636-639 | Body_part | denotes | gut | http://purl.obolibrary.org/obo/UBERON_0001007|http://purl.obolibrary.org/obo/UBERON_0001555|http://purl.obolibrary.org/obo/UBERON_0004907 |
T10 | 1283-1286 | Body_part | denotes | gut | http://purl.obolibrary.org/obo/UBERON_0001007|http://purl.obolibrary.org/obo/UBERON_0001555|http://purl.obolibrary.org/obo/UBERON_0004907 |
GlyCosmos15-MAT
Id | Subject | Object | Predicate | Lexical cue | mat_id |
---|---|---|---|---|---|
T1 | 99-102 | Body_part | denotes | gut | http://purl.obolibrary.org/obo/MAT_0000043 |
T2 | 636-639 | Body_part | denotes | gut | http://purl.obolibrary.org/obo/MAT_0000043 |
T3 | 1283-1286 | Body_part | denotes | gut | http://purl.obolibrary.org/obo/MAT_0000043 |
GlyCosmos15-Sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 0-103 | Sentence | denotes | Carbohydrate Syntrophy enhances the establishment of Bifidobacterium breve UCC2003 in the neonatal gut. |
T2 | 104-304 | Sentence | denotes | The non-digestible oligosaccharide fraction of maternal milk represents an important of carbohydrate and energy source for saccharolytic bifidobacteria in the gastrointestinal tract during early life. |
T3 | 305-515 | Sentence | denotes | However, not all neonatal bifidobacteria isolates can directly metabolise the complex sialylated, fucosylated, sulphated and/or N-acetylglucosamine-containing oligosaccharide structures present in mothers milk. |
T4 | 516-640 | Sentence | denotes | For some bifidobacterial strains, efficient carbohydrate syntrophy or crossfeeding is key to their establishment in the gut. |
T5 | 641-863 | Sentence | denotes | In this study, we have adopted advanced functional genomic approaches to create single and double in-frame deletions of the N-acetyl glucosamine 6-phosphate deacetylase encoding genes, nagA1 and nagA2, of B. breve UCC2003. |
T6 | 864-1287 | Sentence | denotes | In vitro phenotypic analysis followed by in vivo studies on co-colonisation, mother to infant transmission, and evaluation of the relative co-establishment of B. bifidum and B. breve UCC2003 or UCC2003ΔnagA1ΔnagA2 in dam-reared neonatal mice demonstrates the importance of crossfeeding on sialic acid, fucose and N-acetylglucosamine-containing oligosaccharides for the establishment of B. breve UCC2003 in the neonatal gut. |
T7 | 1288-1561 | Sentence | denotes | Furthermore, transcriptomic analysis of in vivo gene expression shows upregulation of genes associated with the utilisation of lactose, sialic acid, GlcNAc-6-S and fucose in B. breve UCC2003, while for UCC2003ΔnagA1ΔnagA2 only genes for lactose metabolism were upregulated. |
GlyCosmos15-NCBITAXON
Id | Subject | Object | Predicate | Lexical cue | db_id |
---|---|---|---|---|---|
T1 | 53-74 | OrganismTaxon | denotes | Bifidobacterium breve | 1685 |
T2 | 1101-1105 | OrganismTaxon | denotes | mice | 10088 |
GlyCosmos15-Glycan
Id | Subject | Object | Predicate | Lexical cue | image |
---|---|---|---|---|---|
T1 | 1415-1422 | Glycan | denotes | lactose | https://api.glycosmos.org/wurcs2image/latest/png/binary/G15541SE |
T2 | 1525-1532 | Glycan | denotes | lactose | https://api.glycosmos.org/wurcs2image/latest/png/binary/G15541SE |
NCBITAXON
Id | Subject | Object | Predicate | Lexical cue | db_id |
---|---|---|---|---|---|
T1 | 53-74 | OrganismTaxon | denotes | Bifidobacterium breve | 1685 |
T2 | 1101-1105 | OrganismTaxon | denotes | mice | 10088 |
Anatomy-UBERON
Id | Subject | Object | Predicate | Lexical cue | uberon_id |
---|---|---|---|---|---|
T1 | 99-102 | Body_part | denotes | gut | http://purl.obolibrary.org/obo/UBERON_0001007|http://purl.obolibrary.org/obo/UBERON_0001555|http://purl.obolibrary.org/obo/UBERON_0004907 |
T4 | 160-164 | Body_part | denotes | milk | http://purl.obolibrary.org/obo/UBERON_0001913 |
T5 | 263-285 | Body_part | denotes | gastrointestinal tract | http://purl.obolibrary.org/obo/UBERON_0005409 |
T6 | 510-514 | Body_part | denotes | milk | http://purl.obolibrary.org/obo/UBERON_0001913 |
T7 | 636-639 | Body_part | denotes | gut | http://purl.obolibrary.org/obo/UBERON_0001007|http://purl.obolibrary.org/obo/UBERON_0001555|http://purl.obolibrary.org/obo/UBERON_0004907 |
T10 | 1283-1286 | Body_part | denotes | gut | http://purl.obolibrary.org/obo/UBERON_0001007|http://purl.obolibrary.org/obo/UBERON_0001555|http://purl.obolibrary.org/obo/UBERON_0004907 |