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sonoma2

Id Subject Object Predicate Lexical cue
T0 0-10 REG denotes Comparison
T1 14-27 GENE denotes procalcitonin
T2 60-69 MPA denotes biomarker
T3 73-80 CPA denotes frailty
T4 85-98 GENE denotes interleukin-6
T5 85-98 GENE denotes interleukin-6
T6 103-113 GENE denotes C-reactive
T7 103-121 GENE denotes C-reactive protein
T8 114-121 GENE denotes protein
T9 170-183 GENE denotes Procalcitonin
T10 185-188 GENE denotes PCT
T11 194-204 REG denotes predictive
T12 228-247 DISEASE denotes infectious disease
T13 229-248 DISEASE denotes infectious diseases
T14 267-274 REG denotes studied
T15 278-285 CPA denotes frailty
T16 328-331 GENE denotes PCT
T17 358-368 MPA denotes biomarkers
T18 369-382 GENE denotes [interleukin-
T19 370-383 GENE denotes interleukin-6
T20 384-388 GENE denotes (IL-
T21 385-389 GENE denotes IL-6
T22 395-413 GENE denotes C-reactive protei
T23 396-414 GENE denotes C-reactive protein
T24 415-418 GENE denotes (CR
T25 416-419 GENE denotes CRP
T26 430-441 REG denotes association
T27 447-454 CPA denotes frailty
T28 574-584 MPA denotes biomarkers
T29 620-627 CPA denotes Frailty
T30 714-725 REG denotes association
T31 729-739 MPA denotes biomarkers
T32 743-752 DISEASE denotes h infecti
T33 745-754 CPA denotes infection
T34 798-807 DISEASE denotes o pneumon
T35 800-809 DISEASE denotes pneumonia
T36 819-829 CPA denotes infections
T37 833-843 DISEASE denotes d "pneumon
T38 836-845 DISEASE denotes pneumonia
T39 1004-1013 DISEASE denotes e pneumon
T40 1006-1015 DISEASE denotes pneumonia
T41 1023-1033 REG denotes Prevalence
T42 1037-1044 CPA denotes frailty
T43 1094-1101 DISEASE denotes frailty
T44 1128-1138 REG denotes associated
T45 1144-1150 POSREG denotes higher
T46 1151-1154 GENE denotes PCT
T47 1157-1161 GENE denotes d IL
T48 1159-1163 GENE denotes IL-6
T49 1164-1170 MPA denotes levels
T50 1177-1180 GENE denotes t C
T51 1179-1182 GENE denotes CRP
T52 1184-1194 REG denotes Prevalence
T53 1198-1205 CPA denotes frailty
T54 1211-1220 DISEASE denotes e pneumon
T55 1213-1222 DISEASE denotes pneumonia
T56 1253-1260 CPA denotes frailty
T57 1265-1275 REG denotes associated
T58 1291-1301 MPA denotes biomarkers
T59 1378-1388 GENE denotes hemoglobin
T60 1390-1397 GENE denotes albumin
T61 1399-1410 CPA denotes neutrophils
T62 1415-1425 GENE denotes creatinine
T63 1427-1430 GENE denotes PCT
T64 1434-1446 GENE denotes t IL-6 and C
T65 1436-1440 GENE denotes IL-6
T66 1445-1448 GENE denotes CRP
T67 1454-1464 REG denotes associated
T68 1470-1477 CPA denotes frailty
T69 1566-1576 MPA denotes biomarkers
T70 1582-1592 REG denotes associated
T71 1598-1605 CPA denotes frailty
T72 1611-1620 DISEASE denotes e pneumon
T73 1613-1622 DISEASE denotes pneumonia
T74 1707-1710 GENE denotes PCT
T75 1716-1720 GENE denotes ot I
T76 1719-1723 GENE denotes IL-6
T77 1724-1727 GENE denotes or
T78 1727-1730 GENE denotes CRP
T79 1736-1746 REG denotes associated
T80 1752-1759 CPA denotes frailty
T81 1788-1797 DISEASE denotes ut infect
T82 1791-1800 DISEASE denotes infection
T83 1816-1826 MPA denotes biomarkers
T84 1832-1842 REG denotes associated
T85 1848-1855 CPA denotes frailty
T86 1873-1882 DISEASE denotes th pneumo
T87 1876-1885 DISEASE denotes pneumonia
R0 T2 T0 ThemeOf biomarker,Comparison
R1 T1 T0 ThemeOf procalcitonin,Comparison
R2 T1 T2 ThemeOf procalcitonin,biomarker
R3 T3 T0 ThemeOf frailty,Comparison
R4 T3 T2 ThemeOf frailty,biomarker
R5 T4 T0 ThemeOf interleukin-6,Comparison
R6 T4 T2 ThemeOf interleukin-6,biomarker
R7 T6 T0 ThemeOf C-reactive,Comparison
R8 T6 T2 ThemeOf C-reactive,biomarker
R9 T6 T8 ThemeOf C-reactive,protein
R10 T8 T0 ThemeOf protein,Comparison
R11 T8 T2 ThemeOf protein,biomarker
R12 T9 T11 ThemeOf Procalcitonin,predictive
R13 T9 T14 ThemeOf Procalcitonin,studied
R14 T10 T11 ThemeOf PCT,predictive
R15 T10 T14 ThemeOf PCT,studied
R16 T11 T14 ThemeOf predictive,studied
R17 T13 T11 ThemeOf infectious diseases,predictive
R18 T13 T14 ThemeOf infectious diseases,studied
R19 T15 T11 ThemeOf frailty,predictive
R20 T15 T14 ThemeOf frailty,studied
R21 T16 T17 ThemeOf PCT,biomarkers
R26 T21 T17 ThemeOf IL-6,biomarkers
R22 T16 T26 ThemeOf PCT,association
R23 T17 T26 ThemeOf biomarkers,association
R24 T19 T17 ThemeOf interleukin-6,biomarkers
R25 T19 T26 ThemeOf interleukin-6,association
R27 T21 T26 ThemeOf IL-6,association
R28 T23 T17 ThemeOf C-reactive protein,biomarkers
R29 T25 T23 ThemeOf CRP,C-reactive protein
R30 T23 T26 ThemeOf C-reactive protein,association
R31 T25 T17 ThemeOf CRP,biomarkers
R32 T25 T26 ThemeOf CRP,association
R33 T27 T26 ThemeOf frailty,association
R34 T31 T30 ThemeOf biomarkers,association
R35 T33 T30 ThemeOf infection,association
R36 T33 T31 ThemeOf infection,biomarkers
R37 T35 T30 ThemeOf pneumonia,association
R38 T35 T31 ThemeOf pneumonia,biomarkers
R39 T36 T30 ThemeOf infections,association
R40 T36 T31 ThemeOf infections,biomarkers
R41 T38 T30 ThemeOf pneumonia,association
R42 T38 T31 ThemeOf pneumonia,biomarkers
R43 T42 T41 ThemeOf frailty,Prevalence
R44 T42 T44 ThemeOf frailty,associated
R45 T42 T45 ThemeOf frailty,higher
R46 T43 T41 ThemeOf frailty,Prevalence
R47 T43 T44 ThemeOf frailty,associated
R48 T46 T44 ThemeOf PCT,associated
R49 T46 T45 ThemeOf PCT,higher
R50 T46 T49 ThemeOf PCT,levels
R51 T48 T44 ThemeOf IL-6,associated
R52 T48 T45 ThemeOf IL-6,higher
R53 T48 T49 ThemeOf IL-6,levels
R54 T49 T41 ThemeOf levels,Prevalence
R55 T49 T44 ThemeOf levels,associated
R56 T49 T45 ThemeOf levels,higher
R57 T51 T41 ThemeOf CRP,Prevalence
R58 T51 T44 ThemeOf CRP,associated
R59 T51 T45 ThemeOf CRP,higher
R60 T51 T49 ThemeOf CRP,levels
R61 T53 T52 ThemeOf frailty,Prevalence
R62 T53 T55 ThemeOf frailty,pneumonia
R63 T53 T57 ThemeOf frailty,associated
R64 T55 T52 ThemeOf pneumonia,Prevalence
R65 T55 T57 ThemeOf pneumonia,associated
R66 T56 T52 ThemeOf frailty,Prevalence
R67 T56 T57 ThemeOf frailty,associated
R68 T56 T58 ThemeOf frailty,biomarkers
R69 T58 T57 ThemeOf biomarkers,associated
R70 T60 T67 ThemeOf albumin,associated
R71 T61 T67 ThemeOf neutrophils,associated
R72 T62 T67 ThemeOf creatinine,associated
R73 T63 T67 ThemeOf PCT,associated
R74 T65 T67 ThemeOf IL-6,associated
R75 T66 T67 ThemeOf CRP,associated
R76 T68 T67 ThemeOf frailty,associated
R77 T69 T70 ThemeOf biomarkers,associated
R78 T71 T70 ThemeOf frailty,associated
R79 T73 T71 ThemeOf pneumonia,frailty
R80 T73 T69 ThemeOf pneumonia,biomarkers
R81 T73 T70 ThemeOf pneumonia,associated
R82 T74 T79 ThemeOf PCT,associated
R83 T74 T83 ThemeOf PCT,biomarkers
R84 T76 T79 ThemeOf IL-6,associated
R85 T76 T83 ThemeOf IL-6,biomarkers
R86 T78 T79 ThemeOf CRP,associated
R87 T78 T83 ThemeOf CRP,biomarkers
R88 T78 T84 ThemeOf CRP,associated
R89 T80 T79 ThemeOf frailty,associated
R90 T80 T83 ThemeOf frailty,biomarkers
R91 T80 T84 ThemeOf frailty,associated
R92 T82 T79 ThemeOf infection,associated
R93 T82 T80 ThemeOf infection,frailty
R94 T82 T83 ThemeOf infection,biomarkers
R95 T82 T84 ThemeOf infection,associated
R96 T83 T79 ThemeOf biomarkers,associated
R97 T83 T84 ThemeOf biomarkers,associated
R98 T85 T83 ThemeOf frailty,biomarkers
R99 T85 T84 ThemeOf frailty,associated
R100 T87 T83 ThemeOf pneumonia,biomarkers
R101 T87 T84 ThemeOf pneumonia,associated

Inflammaging

Id Subject Object Predicate Lexical cue
T1 0-164 Sentence denotes Comparison of procalcitonin, a potentially new inflammatory biomarker of frailty, to interleukin-6 and C-reactive protein among older Chinese hospitalized patients.
T2 165-169 Sentence denotes AIM:
T3 170-286 Sentence denotes Procalcitonin (PCT) has predictive value for patients with infectious diseases, but has not been studied in frailty.
T4 287-489 Sentence denotes The purpose of this study was to compare PCT to two other inflammatory biomarkers [interleukin-6 (IL-6)] and C-reactive protein (CRP) in their association with frailty among older hospitalized patients.
T5 490-498 Sentence denotes METHODS:
T6 499-619 Sentence denotes Retrospective study of inpatients (June-December, 2016), who had all three biomarkers measured within 24 h of admission.
T7 620-702 Sentence denotes Frailty was defined according to the Chinese version of a validated frailty scale.
T8 703-880 Sentence denotes Due to the association of biomarkers with infection, we divided patients into "non-infected" (no pneumonia or other infections) and "pneumonia" (using standard criteria) groups.
T9 881-889 Sentence denotes RESULTS:
T10 890-1022 Sentence denotes Of 435 patients (mean age 81.6 ± 8.6 years), 181 (41.6%) were designated the non-infected group and 254 (58.4%) the pneumonia group.
T11 1023-1183 Sentence denotes Prevalence of frailty in the non-infected group was 32.0% (58/181) and frailty (univariate analysis) was associated with higher PCT and IL-6 levels but not CRP.
T12 1184-1302 Sentence denotes Prevalence of frailty in the pneumonia group was 40.2% (102/254) and frailty was associated with all three biomarkers.
T13 1303-1629 Sentence denotes In multivariable analysis adjusting for age, gender, smoking, alcohol use, hemoglobin, albumin, neutrophils and creatinine, PCT (not IL-6 and CRP) was associated with frailty in the non-infected group (OR = 5.244; 95% CI, 1.622-16.947; P = 0.006) and none of the biomarkers were associated with frailty in the pneumonia group.
T14 1630-1642 Sentence denotes CONCLUSIONS:
T15 1643-1801 Sentence denotes Although the study is limited due to the retrospective methods, PCT but not IL-6 or CRP, was associated with frailty among older inpatients without infection.
T16 1802-1886 Sentence denotes None of these biomarkers were associated with frailty among patients with pneumonia.
T1 0-164 Sentence denotes Comparison of procalcitonin, a potentially new inflammatory biomarker of frailty, to interleukin-6 and C-reactive protein among older Chinese hospitalized patients.
T2 165-169 Sentence denotes AIM:
T3 170-286 Sentence denotes Procalcitonin (PCT) has predictive value for patients with infectious diseases, but has not been studied in frailty.
T4 287-489 Sentence denotes The purpose of this study was to compare PCT to two other inflammatory biomarkers [interleukin-6 (IL-6)] and C-reactive protein (CRP) in their association with frailty among older hospitalized patients.
T5 490-498 Sentence denotes METHODS:
T6 499-619 Sentence denotes Retrospective study of inpatients (June-December, 2016), who had all three biomarkers measured within 24 h of admission.
T7 620-702 Sentence denotes Frailty was defined according to the Chinese version of a validated frailty scale.
T8 703-880 Sentence denotes Due to the association of biomarkers with infection, we divided patients into "non-infected" (no pneumonia or other infections) and "pneumonia" (using standard criteria) groups.
T9 881-889 Sentence denotes RESULTS:
T10 890-1022 Sentence denotes Of 435 patients (mean age 81.6 ± 8.6 years), 181 (41.6%) were designated the non-infected group and 254 (58.4%) the pneumonia group.
T11 1023-1183 Sentence denotes Prevalence of frailty in the non-infected group was 32.0% (58/181) and frailty (univariate analysis) was associated with higher PCT and IL-6 levels but not CRP.
T12 1184-1302 Sentence denotes Prevalence of frailty in the pneumonia group was 40.2% (102/254) and frailty was associated with all three biomarkers.
T13 1303-1629 Sentence denotes In multivariable analysis adjusting for age, gender, smoking, alcohol use, hemoglobin, albumin, neutrophils and creatinine, PCT (not IL-6 and CRP) was associated with frailty in the non-infected group (OR = 5.244; 95% CI, 1.622-16.947; P = 0.006) and none of the biomarkers were associated with frailty in the pneumonia group.
T14 1630-1642 Sentence denotes CONCLUSIONS:
T15 1643-1801 Sentence denotes Although the study is limited due to the retrospective methods, PCT but not IL-6 or CRP, was associated with frailty among older inpatients without infection.
T16 1802-1886 Sentence denotes None of these biomarkers were associated with frailty among patients with pneumonia.