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PubMed:29579213 JSONTXT

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GlyCosmos6-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 251-260 Body_part denotes enveloped http://purl.obolibrary.org/obo/GO_0031975
T2 280-288 Body_part denotes envelope http://purl.obolibrary.org/obo/GO_0031975
T3 289-297 Body_part denotes membrane http://purl.obolibrary.org/obo/GO_0016020|http://purl.obolibrary.org/obo/UBERON_0000094|http://purl.obolibrary.org/obo/UBERON_0000158
T6 320-324 Body_part denotes cell http://purl.obolibrary.org/obo/CL_0000000
T7 507-515 Body_part denotes envelope http://purl.obolibrary.org/obo/GO_0031975
T8 806-810 Body_part denotes cell http://purl.obolibrary.org/obo/CL_0000000
T9 1177-1186 Body_part denotes enveloped http://purl.obolibrary.org/obo/GO_0031975
T10 1376-1380 Body_part denotes cell http://purl.obolibrary.org/obo/CL_0000000
T11 1407-1416 Body_part denotes enveloped http://purl.obolibrary.org/obo/GO_0031975
T12 1430-1437 Body_part denotes simplex http://purl.obolibrary.org/obo/UBERON_0005350

sentences

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-38 Sentence denotes Global aspects of viral glycosylation.
TextSentencer_T2 39-246 Sentence denotes Enveloped viruses encompass some of the most common human pathogens causing infections of different severity, ranging from no or very few symptoms to lethal disease as seen with the viral hemorrhagic fevers.
TextSentencer_T3 247-468 Sentence denotes All enveloped viruses possess an envelope membrane derived from the host cell, modified with often heavily glycosylated virally encoded glycoproteins important for infectivity, viral particle formation and immune evasion.
TextSentencer_T4 469-685 Sentence denotes While N-linked glycosylation of viral envelope proteins is well characterized with respect to location, structure and site occupancy, information on mucin-type O-glycosylation of these proteins is less comprehensive.
TextSentencer_T5 686-893 Sentence denotes Studies on viral glycosylation are often limited to analysis of recombinant proteins that in most cases are produced in cell lines with a glycosylation capacity different from the capacity of the host cells.
TextSentencer_T6 894-1033 Sentence denotes The glycosylation pattern of the produced recombinant glycoproteins might therefore be different from the pattern on native viral proteins.
TextSentencer_T7 1034-1201 Sentence denotes In this review, we provide a historical perspective on analysis of viral glycosylation, and summarize known roles of glycans in the biology of enveloped human viruses.
TextSentencer_T8 1202-1462 Sentence denotes In addition, we describe how to overcome the analytical limitations by using a global approach based on mass spectrometry to identify viral O-glycosylation in virus-infected cell lysates using the complex enveloped virus herpes simplex virus type 1 as a model.
TextSentencer_T9 1463-1655 Sentence denotes We underscore that glycans often pay important contributions to overall protein structure, function and immune recognition, and that glycans represent a crucial determinant for vaccine design.
TextSentencer_T10 1656-1876 Sentence denotes High throughput analysis of glycosylation on relevant glycoprotein formulations, as well as data compilation and sharing is therefore important to identify consensus glycosylation patterns for translational applications.
T1 0-38 Sentence denotes Global aspects of viral glycosylation.
T2 39-246 Sentence denotes Enveloped viruses encompass some of the most common human pathogens causing infections of different severity, ranging from no or very few symptoms to lethal disease as seen with the viral hemorrhagic fevers.
T3 247-468 Sentence denotes All enveloped viruses possess an envelope membrane derived from the host cell, modified with often heavily glycosylated virally encoded glycoproteins important for infectivity, viral particle formation and immune evasion.
T4 469-685 Sentence denotes While N-linked glycosylation of viral envelope proteins is well characterized with respect to location, structure and site occupancy, information on mucin-type O-glycosylation of these proteins is less comprehensive.
T5 686-893 Sentence denotes Studies on viral glycosylation are often limited to analysis of recombinant proteins that in most cases are produced in cell lines with a glycosylation capacity different from the capacity of the host cells.
T6 894-1033 Sentence denotes The glycosylation pattern of the produced recombinant glycoproteins might therefore be different from the pattern on native viral proteins.
T7 1034-1201 Sentence denotes In this review, we provide a historical perspective on analysis of viral glycosylation, and summarize known roles of glycans in the biology of enveloped human viruses.
T8 1202-1462 Sentence denotes In addition, we describe how to overcome the analytical limitations by using a global approach based on mass spectrometry to identify viral O-glycosylation in virus-infected cell lysates using the complex enveloped virus herpes simplex virus type 1 as a model.
T9 1463-1655 Sentence denotes We underscore that glycans often pay important contributions to overall protein structure, function and immune recognition, and that glycans represent a crucial determinant for vaccine design.
T10 1656-1876 Sentence denotes High throughput analysis of glycosylation on relevant glycoprotein formulations, as well as data compilation and sharing is therefore important to identify consensus glycosylation patterns for translational applications.

mondo_disease

Id Subject Object Predicate Lexical cue mondo_id
T1 115-125 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550
T2 221-245 Disease denotes viral hemorrhagic fevers http://purl.obolibrary.org/obo/MONDO_0018087
T3 411-429 Disease denotes infectivity, viral http://purl.obolibrary.org/obo/MONDO_0005108
T4 1423-1437 Disease denotes herpes simplex http://purl.obolibrary.org/obo/MONDO_0004609

GlyCosmos6-CLO

Id Subject Object Predicate Lexical cue
T1 320-324 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T2 806-810 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T3 887-892 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T4 1376-1380 http://purl.obolibrary.org/obo/GO_0005623 denotes cell

NCBITAXON

Id Subject Object Predicate Lexical cue db_id
T1 49-56 OrganismTaxon denotes viruses NCBItxid:10239
T2 91-96 OrganismTaxon denotes human NCBItxid:9606
T3 261-268 OrganismTaxon denotes viruses NCBItxid:10239
T4 1187-1192 OrganismTaxon denotes human NCBItxid:9606
T5 1193-1200 OrganismTaxon denotes viruses NCBItxid:10239
T6 1423-1450 OrganismTaxon denotes herpes simplex virus type 1 NCBItxid:10298