PubMed:29536284 JSONTXT

{"project":"maxiaofeng52_800_3","denotations":[{"id":"T1","span":{"begin":173,"end":176},"obj":"DP"},{"id":"T2","span":{"begin":142,"end":145},"obj":"DP"},{"id":"T3","span":{"begin":251,"end":254},"obj":"DP"},{"id":"T4","span":{"begin":375,"end":378},"obj":"DP"},{"id":"T5","span":{"begin":609,"end":612},"obj":"DP"},{"id":"T6","span":{"begin":688,"end":691},"obj":"DP"}],"text":"Testing the Efficacy of Combined Motivational Interviewing and Cognitive Behavioral Skills Training to Reduce Methamphetamine Use and Improve HIV Medication Adherence Among HIV-Positive Gay and Bisexual Men.\nPrior research has identified subgroups of HIV-positive gay and bisexual men (GBM) based upon information, motivation, and behavioral skills (IMB) profiles related to HIV medication adherence and methamphetamine use. We conducted a randomized controlled trial of a combined motivational interview (MI) and cognitive behavioral therapy (CBT) intervention tailored specifically to the unique context of HIV-positive GBM, and tested whether IMB profiles moderated treatment effects. HIV-positive GBM (N = 210) were randomized to MI + CBT or an attention-matched education control. Both conditions resulted in reduced methamphetamine use, improved medication adherence (and higher CD4 and lower viral loads), and fewer acts of condomless anal sex at 3, 6, 9 and 12 months post-intervention. Furthermore, the MI + CBT condition achieved greater improvements in medication adherence for men who had greater barriers to change compared to similarly-classified men in the control condition, suggesting the importance of pre-intervention profiles for tailoring future interventions."}

{"project":"wangzhuo19_800_3","denotations":[{"id":"T1","span":{"begin":251,"end":254},"obj":"DP"},{"id":"T2","span":{"begin":142,"end":145},"obj":"DP"},{"id":"T3","span":{"begin":173,"end":176},"obj":"DP"},{"id":"T4","span":{"begin":375,"end":378},"obj":"DP"},{"id":"T5","span":{"begin":609,"end":612},"obj":"DP"},{"id":"T6","span":{"begin":688,"end":691},"obj":"DP"}],"text":"Testing the Efficacy of Combined Motivational Interviewing and Cognitive Behavioral Skills Training to Reduce Methamphetamine Use and Improve HIV Medication Adherence Among HIV-Positive Gay and Bisexual Men.\nPrior research has identified subgroups of HIV-positive gay and bisexual men (GBM) based upon information, motivation, and behavioral skills (IMB) profiles related to HIV medication adherence and methamphetamine use. We conducted a randomized controlled trial of a combined motivational interview (MI) and cognitive behavioral therapy (CBT) intervention tailored specifically to the unique context of HIV-positive GBM, and tested whether IMB profiles moderated treatment effects. HIV-positive GBM (N = 210) were randomized to MI + CBT or an attention-matched education control. Both conditions resulted in reduced methamphetamine use, improved medication adherence (and higher CD4 and lower viral loads), and fewer acts of condomless anal sex at 3, 6, 9 and 12 months post-intervention. Furthermore, the MI + CBT condition achieved greater improvements in medication adherence for men who had greater barriers to change compared to similarly-classified men in the control condition, suggesting the importance of pre-intervention profiles for tailoring future interventions."}