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Inflammaging

Id Subject Object Predicate Lexical cue
T1 0-118 Sentence denotes Ileal pouch of ulcerative colitis and familial adenomatous polyposis patients exhibit modulation of autophagy markers.
T2 119-289 Sentence denotes Total retocolectomy with ileal pouch-anal anastomosis (IPAA) is the surgery of choice for patients with ulcerative colitis (UC) that are refractory to clinical treatment.
T3 290-361 Sentence denotes Pouchitis is one of the most common complications after this procedure.
T4 362-433 Sentence denotes Defects in autophagy have been reported in inflammatory bowel diseases.
T5 434-474 Sentence denotes However, there are no studies on the IP.
T6 475-613 Sentence denotes Therefore, we studied markers for autophagy in the IP mucosa of UC and FAP patients comparing them to controls with a normal distal ileum.
T7 614-715 Sentence denotes Sixteen patients with IP in "J" shape, asymptomatic and with endoscopically normal IP were evaluated.
T8 716-786 Sentence denotes The control group consisted of eight patients with normal colonoscopy.
T9 787-893 Sentence denotes There was a significant decrease in the transcriptional levels of ATG5, MAP1LC3A and BAX in the FAP group.
T10 894-1001 Sentence denotes There was also a decrease in the protein level of Beclin-1 in the UC and FAP compared to the control group.
T11 1002-1189 Sentence denotes Although the LC3II levels by immunoblot were higher in the UC group, LC3/p62 co-localization were lower in the immunofluorescence analysis in the UC and FAP compared to the control group.
T12 1190-1278 Sentence denotes Corroborating these results, there was an increase of p62 by immunoblot in the UC group.
T13 1279-1411 Sentence denotes These findings indicated a modulation of macroautophagy markers in the IP, which may explain the mucosa inflammation predisposition.
T1 0-118 Sentence denotes Ileal pouch of ulcerative colitis and familial adenomatous polyposis patients exhibit modulation of autophagy markers.
T2 119-289 Sentence denotes Total retocolectomy with ileal pouch-anal anastomosis (IPAA) is the surgery of choice for patients with ulcerative colitis (UC) that are refractory to clinical treatment.
T3 290-361 Sentence denotes Pouchitis is one of the most common complications after this procedure.
T4 362-433 Sentence denotes Defects in autophagy have been reported in inflammatory bowel diseases.
T5 434-474 Sentence denotes However, there are no studies on the IP.
T6 475-613 Sentence denotes Therefore, we studied markers for autophagy in the IP mucosa of UC and FAP patients comparing them to controls with a normal distal ileum.
T7 614-715 Sentence denotes Sixteen patients with IP in "J" shape, asymptomatic and with endoscopically normal IP were evaluated.
T8 716-786 Sentence denotes The control group consisted of eight patients with normal colonoscopy.
T9 787-893 Sentence denotes There was a significant decrease in the transcriptional levels of ATG5, MAP1LC3A and BAX in the FAP group.
T10 894-1001 Sentence denotes There was also a decrease in the protein level of Beclin-1 in the UC and FAP compared to the control group.
T11 1002-1189 Sentence denotes Although the LC3II levels by immunoblot were higher in the UC group, LC3/p62 co-localization were lower in the immunofluorescence analysis in the UC and FAP compared to the control group.
T12 1190-1278 Sentence denotes Corroborating these results, there was an increase of p62 by immunoblot in the UC group.
T13 1279-1411 Sentence denotes These findings indicated a modulation of macroautophagy markers in the IP, which may explain the mucosa inflammation predisposition.

GlyCosmos15-Glycan

Id Subject Object Predicate Lexical cue image
T1 1071-1074 Glycan denotes LC3 https://api.glycosmos.org/wurcs2image/latest/png/binary/G06239NA

mondo_disease

Id Subject Object Predicate Lexical cue mondo_id
T1 15-33 Disease denotes ulcerative colitis http://purl.obolibrary.org/obo/MONDO_0005101|http://purl.obolibrary.org/obo/MONDO_0009960
T3 38-68 Disease denotes familial adenomatous polyposis http://purl.obolibrary.org/obo/MONDO_0021055
T4 223-241 Disease denotes ulcerative colitis http://purl.obolibrary.org/obo/MONDO_0005101|http://purl.obolibrary.org/obo/MONDO_0009960
T6 243-245 Disease denotes UC http://purl.obolibrary.org/obo/MONDO_0005101
T7 290-299 Disease denotes Pouchitis http://purl.obolibrary.org/obo/MONDO_0005312
T8 405-432 Disease denotes inflammatory bowel diseases http://purl.obolibrary.org/obo/MONDO_0005265
T9 539-541 Disease denotes UC http://purl.obolibrary.org/obo/MONDO_0005101
T10 546-549 Disease denotes FAP http://purl.obolibrary.org/obo/MONDO_0021055
T11 883-886 Disease denotes FAP http://purl.obolibrary.org/obo/MONDO_0021055
T12 960-962 Disease denotes UC http://purl.obolibrary.org/obo/MONDO_0005101
T13 967-970 Disease denotes FAP http://purl.obolibrary.org/obo/MONDO_0021055
T14 1061-1063 Disease denotes UC http://purl.obolibrary.org/obo/MONDO_0005101
T15 1148-1150 Disease denotes UC http://purl.obolibrary.org/obo/MONDO_0005101
T16 1155-1158 Disease denotes FAP http://purl.obolibrary.org/obo/MONDO_0021055
T17 1269-1271 Disease denotes UC http://purl.obolibrary.org/obo/MONDO_0005101
T18 1376-1395 Disease denotes mucosa inflammation http://purl.obolibrary.org/obo/MONDO_0020579

GlyCosmos15-HP

Id Subject Object Predicate Lexical cue hp_id
T1 15-33 Phenotype denotes ulcerative colitis HP:0100279
T2 223-241 Phenotype denotes ulcerative colitis HP:0100279
T3 243-245 Phenotype denotes UC HP:0100279
T4 405-432 Phenotype denotes inflammatory bowel diseases HP:0002037
T5 539-541 Phenotype denotes UC HP:0100279
T6 960-962 Phenotype denotes UC HP:0100279
T7 1061-1063 Phenotype denotes UC HP:0100279
T8 1148-1150 Phenotype denotes UC HP:0100279
T9 1269-1271 Phenotype denotes UC HP:0100279

GlyCosmos15-Sentences

Id Subject Object Predicate Lexical cue
T1 0-118 Sentence denotes Ileal pouch of ulcerative colitis and familial adenomatous polyposis patients exhibit modulation of autophagy markers.
T2 119-289 Sentence denotes Total retocolectomy with ileal pouch-anal anastomosis (IPAA) is the surgery of choice for patients with ulcerative colitis (UC) that are refractory to clinical treatment.
T3 290-361 Sentence denotes Pouchitis is one of the most common complications after this procedure.
T4 362-433 Sentence denotes Defects in autophagy have been reported in inflammatory bowel diseases.
T5 434-474 Sentence denotes However, there are no studies on the IP.
T6 475-613 Sentence denotes Therefore, we studied markers for autophagy in the IP mucosa of UC and FAP patients comparing them to controls with a normal distal ileum.
T7 614-715 Sentence denotes Sixteen patients with IP in "J" shape, asymptomatic and with endoscopically normal IP were evaluated.
T8 716-786 Sentence denotes The control group consisted of eight patients with normal colonoscopy.
T9 787-893 Sentence denotes There was a significant decrease in the transcriptional levels of ATG5, MAP1LC3A and BAX in the FAP group.
T10 894-1001 Sentence denotes There was also a decrease in the protein level of Beclin-1 in the UC and FAP compared to the control group.
T11 1002-1189 Sentence denotes Although the LC3II levels by immunoblot were higher in the UC group, LC3/p62 co-localization were lower in the immunofluorescence analysis in the UC and FAP compared to the control group.
T12 1190-1278 Sentence denotes Corroborating these results, there was an increase of p62 by immunoblot in the UC group.
T13 1279-1411 Sentence denotes These findings indicated a modulation of macroautophagy markers in the IP, which may explain the mucosa inflammation predisposition.

GlyCosmos15-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T1 15-33 Disease denotes ulcerative colitis MONDO:0009960|MONDO:0005101
T3 38-68 Disease denotes familial adenomatous polyposis MONDO:0021055
T4 223-241 Disease denotes ulcerative colitis MONDO:0009960|MONDO:0005101
T6 243-245 Disease denotes UC MONDO:0009960|MONDO:0005101
T8 290-299 Disease denotes Pouchitis MONDO:0005312
T9 405-432 Disease denotes inflammatory bowel diseases MONDO:0005265
T10 539-541 Disease denotes UC MONDO:0009960|MONDO:0005101
T12 960-962 Disease denotes UC MONDO:0009960|MONDO:0005101
T14 1061-1063 Disease denotes UC MONDO:0009960|MONDO:0005101
T16 1148-1150 Disease denotes UC MONDO:0009960|MONDO:0005101
T18 1269-1271 Disease denotes UC MONDO:0009960|MONDO:0005101
T20 1376-1395 Disease denotes mucosa inflammation MONDO:0020579

GlyCosmos15-Taxon

Id Subject Object Predicate Lexical cue db_id
T1 69-77 Organism denotes patients 9606
T2 209-217 Organism denotes patients 9606
T3 550-558 Organism denotes patients 9606
T4 622-630 Organism denotes patients 9606
T5 753-761 Organism denotes patients 9606

GlyCosmos15-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 6-11 Body_part denotes pouch http://purl.obolibrary.org/obo/UBERON_0009118|http://purl.obolibrary.org/obo/UBERON_0009856
T3 150-155 Body_part denotes pouch http://purl.obolibrary.org/obo/UBERON_0009118|http://purl.obolibrary.org/obo/UBERON_0009856
T5 418-423 Body_part denotes bowel http://purl.obolibrary.org/obo/UBERON_0000160
T6 529-535 Body_part denotes mucosa http://purl.obolibrary.org/obo/UBERON_0000344
T7 607-612 Body_part denotes ileum http://purl.obolibrary.org/obo/UBERON_0002116
T8 1376-1382 Body_part denotes mucosa http://purl.obolibrary.org/obo/UBERON_0000344

GlyCosmos15-FMA

Id Subject Object Predicate Lexical cue db_id
T1 161-172 Body_part denotes anastomosis FMA:3726
T2 418-423 Body_part denotes bowel FMA:7199
T3 529-535 Body_part denotes mucosa FMA:85355
T4 607-612 Body_part denotes ileum FMA:7208
T5 1376-1382 Body_part denotes mucosa FMA:85355

GlyCosmos15-MAT

Id Subject Object Predicate Lexical cue mat_id
T1 607-612 Body_part denotes ileum http://purl.obolibrary.org/obo/MAT_0000282

Anatomy-MAT

Id Subject Object Predicate Lexical cue mat_id
T1 607-612 Body_part denotes ileum http://purl.obolibrary.org/obo/MAT_0000282

Anatomy-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 6-11 Body_part denotes pouch http://purl.obolibrary.org/obo/UBERON_0009118|http://purl.obolibrary.org/obo/UBERON_0009856
T3 150-155 Body_part denotes pouch http://purl.obolibrary.org/obo/UBERON_0009118|http://purl.obolibrary.org/obo/UBERON_0009856
T5 418-423 Body_part denotes bowel http://purl.obolibrary.org/obo/UBERON_0000160
T6 529-535 Body_part denotes mucosa http://purl.obolibrary.org/obo/UBERON_0000344
T7 607-612 Body_part denotes ileum http://purl.obolibrary.org/obo/UBERON_0002116
T8 1376-1382 Body_part denotes mucosa http://purl.obolibrary.org/obo/UBERON_0000344

HP-phenotype

Id Subject Object Predicate Lexical cue hp_id
T1 15-33 Phenotype denotes ulcerative colitis HP:0100279
T2 223-241 Phenotype denotes ulcerative colitis HP:0100279
T3 243-245 Phenotype denotes UC HP:0100279
T4 405-432 Phenotype denotes inflammatory bowel diseases HP:0002037
T5 539-541 Phenotype denotes UC HP:0100279
T6 960-962 Phenotype denotes UC HP:0100279
T7 1061-1063 Phenotype denotes UC HP:0100279
T8 1148-1150 Phenotype denotes UC HP:0100279
T9 1269-1271 Phenotype denotes UC HP:0100279