PubMed:29367698
Annnotations
mondo_disease
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T1 | 216-235 | Disease | denotes | rotavirus infection | http://purl.obolibrary.org/obo/MONDO_0005194 |
Anatomy-MAT
| Id | Subject | Object | Predicate | Lexical cue | mat_id |
|---|---|---|---|---|---|
| T1 | 113-118 | Body_part | denotes | blood | http://purl.obolibrary.org/obo/MAT_0000083|http://purl.obolibrary.org/obo/MAT_0000315 |
| T3 | 448-454 | Body_part | denotes | saliva | http://purl.obolibrary.org/obo/MAT_0000444 |
| T4 | 985-990 | Body_part | denotes | blood | http://purl.obolibrary.org/obo/MAT_0000083|http://purl.obolibrary.org/obo/MAT_0000315 |
| T6 | 1108-1113 | Body_part | denotes | blood | http://purl.obolibrary.org/obo/MAT_0000083|http://purl.obolibrary.org/obo/MAT_0000315 |
Glycan-GlyCosmos
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 4-11 | Glycan | denotes | Lewis A | https://api.glycosmos.org/wurcs2image/latest/png/binary/G39023AU |
| T2 | 704-711 | Glycan | denotes | Lewis A | https://api.glycosmos.org/wurcs2image/latest/png/binary/G39023AU |
| T3 | 825-832 | Glycan | denotes | Lewis B | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00048MO |
GlyCosmos-GlycoEpitope
| Id | Subject | Object | Predicate | Lexical cue | glycoepitope_id |
|---|---|---|---|---|---|
| T1 | 4-11 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | Lewis A | http://www.glycoepitope.jp/epitopes/EP0007 |
| T2 | 704-711 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | Lewis A | http://www.glycoepitope.jp/epitopes/EP0007 |
| T3 | 825-832 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | Lewis B | http://www.glycoepitope.jp/epitopes/EP0010 |
GlyCosmos15-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T1 | 216-235 | Disease | denotes | rotavirus infection | http://purl.obolibrary.org/obo/MONDO_0005194 |
GlyCosmos15-NCBITAXON
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 216-225 | OrganismTaxon | denotes | rotavirus | 10912 |
GlyCosmos15-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 113-118 | Body_part | denotes | blood | http://purl.obolibrary.org/obo/UBERON_0000178 |
| T2 | 448-454 | Body_part | denotes | saliva | http://purl.obolibrary.org/obo/UBERON_0001836 |
| T3 | 534-540 | Body_part | denotes | plasma | http://purl.obolibrary.org/obo/UBERON_0001969 |
| T4 | 985-990 | Body_part | denotes | blood | http://purl.obolibrary.org/obo/UBERON_0000178 |
| T5 | 1108-1113 | Body_part | denotes | blood | http://purl.obolibrary.org/obo/UBERON_0000178 |
GlyCosmos15-MAT
| Id | Subject | Object | Predicate | Lexical cue | mat_id |
|---|---|---|---|---|---|
| T1 | 113-118 | Body_part | denotes | blood | http://purl.obolibrary.org/obo/MAT_0000083|http://purl.obolibrary.org/obo/MAT_0000315 |
| T3 | 448-454 | Body_part | denotes | saliva | http://purl.obolibrary.org/obo/MAT_0000444 |
| T4 | 985-990 | Body_part | denotes | blood | http://purl.obolibrary.org/obo/MAT_0000083|http://purl.obolibrary.org/obo/MAT_0000315 |
| T6 | 1108-1113 | Body_part | denotes | blood | http://purl.obolibrary.org/obo/MAT_0000083|http://purl.obolibrary.org/obo/MAT_0000315 |
GlyCosmos15-Sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-106 | Sentence | denotes | The Lewis A phenotype is a restriction factor for Rotateq and Rotarix vaccine-take in Nicaraguan children. |
| T2 | 107-267 | Sentence | denotes | Histo-blood group antigens (HBGAs) and the Lewis and secretor antigens are associated with susceptibility to rotavirus infection in a genotype-dependent manner. |
| T3 | 268-400 | Sentence | denotes | Nicaraguan children were prospectively enrolled in two cohorts vaccinated with either RotaTeq RV5 (n = 68) or Rotarix RV1 (n = 168). |
| T4 | 401-482 | Sentence | denotes | Lewis and secretor antigens were determined by saliva phenotyping and genotyping. |
| T5 | 483-622 | Sentence | denotes | Seroconversion was defined as a 4-fold increase in plasma IgA antibody titer 1 month after administration of the first dose of the vaccine. |
| T6 | 623-904 | Sentence | denotes | Regardless of the vaccine administered, significantly fewer of the children with Lewis A phenotype (0/14) seroconverted after receiving the first vaccine dose compared to 26% (45/175) of those with the Lewis B phenotype and 32% (15/47) of the Lewis negative individuals (P < 0.01). |
| T7 | 905-1152 | Sentence | denotes | Furthermore, following administration of the RV1 vaccine, secretor-positive ABO blood group B children seroconverted to a significantly lesser extent (5%) compared to secretor-positive children with ABO blood groups A (26%) and O (27%) (P < 0.05). |
| T8 | 1153-1274 | Sentence | denotes | Other factors such as pre-vaccination titers, sex, breastfeeding, and calprotectin levels did not influence vaccine-take. |
| T9 | 1275-1438 | Sentence | denotes | Differences in HBGA expression appear to be a contributing factor in the discrepancy in vaccine-take and thus, in vaccine efficacy in different ethnic populations. |
GlyCosmos15-Glycan
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 4-11 | Glycan | denotes | Lewis A | https://api.glycosmos.org/wurcs2image/latest/png/binary/G39023AU |
| T2 | 704-711 | Glycan | denotes | Lewis A | https://api.glycosmos.org/wurcs2image/latest/png/binary/G39023AU |
| T3 | 825-832 | Glycan | denotes | Lewis B | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00048MO |
GlyCosmos15-GlycoEpitope
| Id | Subject | Object | Predicate | Lexical cue | glycoepitope_id |
|---|---|---|---|---|---|
| T1 | 4-11 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | Lewis A | http://www.glycoepitope.jp/epitopes/EP0007 |
| T2 | 704-711 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | Lewis A | http://www.glycoepitope.jp/epitopes/EP0007 |
| T3 | 825-832 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | Lewis B | http://www.glycoepitope.jp/epitopes/EP0010 |
NCBITAXON
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 216-225 | OrganismTaxon | denotes | rotavirus | 10912 |
Anatomy-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 113-118 | Body_part | denotes | blood | http://purl.obolibrary.org/obo/UBERON_0000178 |
| T2 | 448-454 | Body_part | denotes | saliva | http://purl.obolibrary.org/obo/UBERON_0001836 |
| T3 | 534-540 | Body_part | denotes | plasma | http://purl.obolibrary.org/obo/UBERON_0001969 |
| T4 | 985-990 | Body_part | denotes | blood | http://purl.obolibrary.org/obo/UBERON_0000178 |
| T5 | 1108-1113 | Body_part | denotes | blood | http://purl.obolibrary.org/obo/UBERON_0000178 |