PubMed:29291351 / 776-945 JSONTXT

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    Inflammaging

    {"project":"Inflammaging","denotations":[{"id":"T8","span":{"begin":0,"end":169},"obj":"Sentence"},{"id":"T8","span":{"begin":0,"end":169},"obj":"Sentence"}],"text":"Mechanistically, CYLD interacts directly with the kinase TAK1 and removes its K63-linked polyubiquitin chain, which blocks downstream activation of the JNK-p38 cascades."}

    sonoma

    {"project":"sonoma","denotations":[{"id":"T-16","span":{"begin":17,"end":21},"obj":"GENE"},{"id":"T-17","span":{"begin":57,"end":61},"obj":"GENE"},{"id":"T-18","span":{"begin":66,"end":73},"obj":"NEGREG"},{"id":"T-19","span":{"begin":116,"end":122},"obj":"NEGREG"}],"relations":[{"id":"R-12","pred":"ThemeOf","subj":"T-18","obj":"T-19"}],"text":"Mechanistically, CYLD interacts directly with the kinase TAK1 and removes its K63-linked polyubiquitin chain, which blocks downstream activation of the JNK-p38 cascades."}