> top > docs > PubMed:29197581 > annotations

PubMed:29197581 JSONTXT

Annnotations TAB JSON ListView MergeView

sentences

Id Subject Object Predicate Lexical cue
T1 0-48 Sentence denotes Proteomic analysis of Bombyx mori molting fluid:
T2 49-83 Sentence denotes Insights into the molting process.
T3 84-196 Sentence denotes Molting is an essential biological process occurring multiple times throughout the life cycle of most Ecdysozoa.
T4 197-284 Sentence denotes Molting fluids accumulate and function in the exuvial space during the molting process.
T5 285-465 Sentence denotes In this study, we used liquid chromatography-tandem mass spectrometry to investigate the molting fluids to analyze the molecular mechanisms of molting in the silkworm, Bombyx mori.
T6 466-692 Sentence denotes In total, 375 proteins were identified in molting fluids from the silkworm at 14-16h before pupation and eclosion, including 12 chitin metabolism-related enzymes, 35 serine proteases, 15 peptidases, and 38 protease inhibitors.
T7 693-803 Sentence denotes Gene ontology analysis indicated that "catalytic" constitutes the most enriched function in the molting fluid.
T8 804-951 Sentence denotes Gene expression patterns and bioinformatic analyses suggested that numerous enzymes are involved in the degradation of cuticle proteins and chitin.
T9 952-1111 Sentence denotes Protein-protein interaction network and activity analyses showed that protease inhibitors are involved in the regulation of multiple pathways in molting fluid.
T10 1112-1208 Sentence denotes Additionally, many immune-related proteins may be involved in the immune defense during molting.
T11 1209-1427 Sentence denotes These results provide a comprehensive proteomic insight into proteolytic enzymes and protease inhibitors in molting fluid, and will likely improve the current understanding of physiological processes in insect molting.
T12 1428-1452 Sentence denotes BIOLOGICAL SIGNIFICANCE:
T13 1453-1512 Sentence denotes Insect molting constitutes a dynamic physiological process.
T14 1513-1677 Sentence denotes To better understand this process, we used LC-MS/MS to investigate the proteome of silkworm molting fluids and identified key proteins involved in silkworm molting.
T15 1678-1826 Sentence denotes The biological processes of the old cuticle degradation pathway and immune defense response were analyzed in the proteome of silkworm molting fluid.
T16 1827-1924 Sentence denotes We report that protease inhibitors serve as key factors in the regulation of the molting process.
T17 1925-2012 Sentence denotes The proteomic results provide new insight into biological molting processes in insects.
T1 0-48 Sentence denotes Proteomic analysis of Bombyx mori molting fluid:
T2 49-83 Sentence denotes Insights into the molting process.
T3 84-196 Sentence denotes Molting is an essential biological process occurring multiple times throughout the life cycle of most Ecdysozoa.
T4 197-284 Sentence denotes Molting fluids accumulate and function in the exuvial space during the molting process.
T5 285-465 Sentence denotes In this study, we used liquid chromatography-tandem mass spectrometry to investigate the molting fluids to analyze the molecular mechanisms of molting in the silkworm, Bombyx mori.
T6 466-692 Sentence denotes In total, 375 proteins were identified in molting fluids from the silkworm at 14-16h before pupation and eclosion, including 12 chitin metabolism-related enzymes, 35 serine proteases, 15 peptidases, and 38 protease inhibitors.
T7 693-803 Sentence denotes Gene ontology analysis indicated that "catalytic" constitutes the most enriched function in the molting fluid.
T8 804-951 Sentence denotes Gene expression patterns and bioinformatic analyses suggested that numerous enzymes are involved in the degradation of cuticle proteins and chitin.
T9 952-1111 Sentence denotes Protein-protein interaction network and activity analyses showed that protease inhibitors are involved in the regulation of multiple pathways in molting fluid.
T10 1112-1208 Sentence denotes Additionally, many immune-related proteins may be involved in the immune defense during molting.
T11 1209-1427 Sentence denotes These results provide a comprehensive proteomic insight into proteolytic enzymes and protease inhibitors in molting fluid, and will likely improve the current understanding of physiological processes in insect molting.
T12 1428-1452 Sentence denotes BIOLOGICAL SIGNIFICANCE:
T13 1453-1512 Sentence denotes Insect molting constitutes a dynamic physiological process.
T14 1513-1677 Sentence denotes To better understand this process, we used LC-MS/MS to investigate the proteome of silkworm molting fluids and identified key proteins involved in silkworm molting.
T15 1678-1826 Sentence denotes The biological processes of the old cuticle degradation pathway and immune defense response were analyzed in the proteome of silkworm molting fluid.
T16 1827-1924 Sentence denotes We report that protease inhibitors serve as key factors in the regulation of the molting process.
T17 1925-2012 Sentence denotes The proteomic results provide new insight into biological molting processes in insects.

Glycosmos6-MAT

Id Subject Object Predicate Lexical cue
T1 923-930 http://purl.obolibrary.org/obo/MAT_0000150 denotes cuticle
T2 1714-1721 http://purl.obolibrary.org/obo/MAT_0000150 denotes cuticle

silkworm

Id Subject Object Predicate Lexical cue
T1 22-33 Species:7091 denotes Bombyx mori
T2 186-195 Species:1206794 denotes Ecdysozoa
T3 443-451 Species:7091 denotes silkworm
T4 453-464 Species:7091 denotes Bombyx mori
T5 532-540 Species:7091 denotes silkworm
T6 594-600 Chemical:MESH:D002686 denotes chitin
T7 1596-1604 Species:7091 denotes silkworm
T8 1660-1668 Species:7091 denotes silkworm
T9 1803-1811 Species:7091 denotes silkworm

silkwormbase

Id Subject Object Predicate Lexical cue
T1 22-33 Species:7091 denotes Bombyx mori
T2 186-195 Species:1206794 denotes Ecdysozoa
T3 443-451 Species:7091 denotes silkworm
T4 453-464 Species:7091 denotes Bombyx mori
T5 532-540 Species:7091 denotes silkworm
T6 594-600 Chemical:MESH:D002686 denotes chitin
T7 1596-1604 Species:7091 denotes silkworm
T8 1660-1668 Species:7091 denotes silkworm
T9 1803-1811 Species:7091 denotes silkworm

GlyCosmos15-Glycan

Id Subject Object Predicate Lexical cue image
T1 594-600 Glycan denotes chitin https://api.glycosmos.org/wurcs2image/latest/png/binary/G97099AY
T2 944-950 Glycan denotes chitin https://api.glycosmos.org/wurcs2image/latest/png/binary/G97099AY

Anatomy-MAT

Id Subject Object Predicate Lexical cue mat_id
T1 923-930 Body_part denotes cuticle http://purl.obolibrary.org/obo/MAT_0000150
T2 1714-1721 Body_part denotes cuticle http://purl.obolibrary.org/obo/MAT_0000150

Glycan-GlyCosmos

Id Subject Object Predicate Lexical cue image
T1 594-600 Glycan denotes chitin https://api.glycosmos.org/wurcs2image/latest/png/binary/G97099AY
T2 944-950 Glycan denotes chitin https://api.glycosmos.org/wurcs2image/latest/png/binary/G97099AY

GlyCosmos15-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 42-47 Body_part denotes fluid http://purl.obolibrary.org/obo/UBERON_0006314
T2 251-256 Body_part denotes space http://purl.obolibrary.org/obo/UBERON_0000464
T3 797-802 Body_part denotes fluid http://purl.obolibrary.org/obo/UBERON_0006314
T4 923-930 Body_part denotes cuticle http://purl.obolibrary.org/obo/UBERON_0001001|http://purl.obolibrary.org/obo/UBERON_0001002|http://purl.obolibrary.org/obo/UBERON_0004882
T7 1105-1110 Body_part denotes fluid http://purl.obolibrary.org/obo/UBERON_0006314
T8 1325-1330 Body_part denotes fluid http://purl.obolibrary.org/obo/UBERON_0006314
T9 1714-1721 Body_part denotes cuticle http://purl.obolibrary.org/obo/UBERON_0001001|http://purl.obolibrary.org/obo/UBERON_0001002|http://purl.obolibrary.org/obo/UBERON_0004882
T12 1820-1825 Body_part denotes fluid http://purl.obolibrary.org/obo/UBERON_0006314

GlyCosmos15-Taxon

Id Subject Object Predicate Lexical cue db_id
T1 22-33 Organism denotes Bombyx mori 7091
T2 186-195 Organism denotes Ecdysozoa 1206794
T3 443-451 Organism denotes silkworm 7091
T4 453-464 Organism denotes Bombyx mori 7091
T5 532-540 Organism denotes silkworm 7091
T6 1596-1604 Organism denotes silkworm 7091
T7 1660-1668 Organism denotes silkworm 7091
T8 1803-1811 Organism denotes silkworm 7091

GlyCosmos15-Sentences

Id Subject Object Predicate Lexical cue
T1 0-48 Sentence denotes Proteomic analysis of Bombyx mori molting fluid:
T2 49-83 Sentence denotes Insights into the molting process.
T3 84-284 Sentence denotes Molting is an essential biological process occurring multiple times throughout the life cycle of most Ecdysozoa. Molting fluids accumulate and function in the exuvial space during the molting process.
T4 285-465 Sentence denotes In this study, we used liquid chromatography-tandem mass spectrometry to investigate the molting fluids to analyze the molecular mechanisms of molting in the silkworm, Bombyx mori.
T5 466-692 Sentence denotes In total, 375 proteins were identified in molting fluids from the silkworm at 14-16h before pupation and eclosion, including 12 chitin metabolism-related enzymes, 35 serine proteases, 15 peptidases, and 38 protease inhibitors.
T6 693-803 Sentence denotes Gene ontology analysis indicated that "catalytic" constitutes the most enriched function in the molting fluid.
T7 804-951 Sentence denotes Gene expression patterns and bioinformatic analyses suggested that numerous enzymes are involved in the degradation of cuticle proteins and chitin.
T8 952-1111 Sentence denotes Protein-protein interaction network and activity analyses showed that protease inhibitors are involved in the regulation of multiple pathways in molting fluid.
T9 1112-1208 Sentence denotes Additionally, many immune-related proteins may be involved in the immune defense during molting.
T10 1209-1427 Sentence denotes These results provide a comprehensive proteomic insight into proteolytic enzymes and protease inhibitors in molting fluid, and will likely improve the current understanding of physiological processes in insect molting.
T11 1428-1452 Sentence denotes BIOLOGICAL SIGNIFICANCE:
T12 1453-1512 Sentence denotes Insect molting constitutes a dynamic physiological process.
T13 1513-1677 Sentence denotes To better understand this process, we used LC-MS/MS to investigate the proteome of silkworm molting fluids and identified key proteins involved in silkworm molting.
T14 1678-1826 Sentence denotes The biological processes of the old cuticle degradation pathway and immune defense response were analyzed in the proteome of silkworm molting fluid.
T15 1827-1924 Sentence denotes We report that protease inhibitors serve as key factors in the regulation of the molting process.
T16 1925-2012 Sentence denotes The proteomic results provide new insight into biological molting processes in insects.

GlyCosmos15-MAT

Id Subject Object Predicate Lexical cue mat_id
T1 923-930 Body_part denotes cuticle http://purl.obolibrary.org/obo/MAT_0000150
T2 1714-1721 Body_part denotes cuticle http://purl.obolibrary.org/obo/MAT_0000150

NCBITAXON

Id Subject Object Predicate Lexical cue db_id
T1 22-33 OrganismTaxon denotes Bombyx mori 7091
T2 186-195 OrganismTaxon denotes Ecdysozoa 1206794
T3 443-451 OrganismTaxon denotes silkworm 7091
T4 453-464 OrganismTaxon denotes Bombyx mori 7091
T5 532-540 OrganismTaxon denotes silkworm 7091
T6 1596-1604 OrganismTaxon denotes silkworm 7091
T7 1660-1668 OrganismTaxon denotes silkworm 7091
T8 1803-1811 OrganismTaxon denotes silkworm 7091

Anatomy-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 42-47 Body_part denotes fluid http://purl.obolibrary.org/obo/UBERON_0006314
T2 251-256 Body_part denotes space http://purl.obolibrary.org/obo/UBERON_0000464
T3 797-802 Body_part denotes fluid http://purl.obolibrary.org/obo/UBERON_0006314
T4 923-930 Body_part denotes cuticle http://purl.obolibrary.org/obo/UBERON_0001001|http://purl.obolibrary.org/obo/UBERON_0001002|http://purl.obolibrary.org/obo/UBERON_0004882
T7 1105-1110 Body_part denotes fluid http://purl.obolibrary.org/obo/UBERON_0006314
T8 1325-1330 Body_part denotes fluid http://purl.obolibrary.org/obo/UBERON_0006314
T9 1714-1721 Body_part denotes cuticle http://purl.obolibrary.org/obo/UBERON_0001001|http://purl.obolibrary.org/obo/UBERON_0001002|http://purl.obolibrary.org/obo/UBERON_0004882
T12 1820-1825 Body_part denotes fluid http://purl.obolibrary.org/obo/UBERON_0006314