PubMed:29170521
Annnotations
HP-phenotype
| Id | Subject | Object | Predicate | Lexical cue | hp_id |
|---|---|---|---|---|---|
| T1 | 268-285 | Phenotype | denotes | neurodegeneration | HP:0002180 |
Glycan-GlyCosmos
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 456-459 | Glycan | denotes | GM2 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G79389NT |
| T2 | 464-467 | Glycan | denotes | GM3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G91237TK |
| T3 | 895-898 | Glycan | denotes | GM2 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G79389NT |
| T4 | 903-906 | Glycan | denotes | GM3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G91237TK |
| T5 | 1066-1069 | Glycan | denotes | GM3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G91237TK |
| T6 | 1153-1156 | Glycan | denotes | GM1 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G48558GR |
GlyCosmos-GlycoEpitope
| Id | Subject | Object | Predicate | Lexical cue | glycoepitope_id |
|---|---|---|---|---|---|
| T1 | 1153-1156 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | GM1 | http://www.glycoepitope.jp/epitopes/EP0050 |
GlyCosmos15-HP
| Id | Subject | Object | Predicate | Lexical cue | hp_id |
|---|---|---|---|---|---|
| T1 | 268-285 | Phenotype | denotes | neurodegeneration | HP:0002180 |
GlyCosmos15-NCBITAXON
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 105-108 | OrganismTaxon | denotes | rat | 10114|10116 |
| T3 | 722-726 | OrganismTaxon | denotes | rats | 10114|10116 |
GlyCosmos15-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 109-114 | Body_part | denotes | brain | http://purl.obolibrary.org/obo/UBERON_0000955|http://purl.obolibrary.org/obo/UBERON_6110636 |
| T3 | 392-397 | Body_part | denotes | brain | http://purl.obolibrary.org/obo/UBERON_0000955|http://purl.obolibrary.org/obo/UBERON_6110636 |
| T5 | 833-838 | Body_part | denotes | brain | http://purl.obolibrary.org/obo/UBERON_0000955|http://purl.obolibrary.org/obo/UBERON_6110636 |
| T7 | 988-1003 | Body_part | denotes | corpus callosum | http://purl.obolibrary.org/obo/UBERON_0002336 |
| T8 | 1448-1453 | Body_part | denotes | brain | http://purl.obolibrary.org/obo/UBERON_0000955|http://purl.obolibrary.org/obo/UBERON_6110636 |
GlyCosmos15-MAT
| Id | Subject | Object | Predicate | Lexical cue | mat_id |
|---|---|---|---|---|---|
| T1 | 109-114 | Body_part | denotes | brain | http://purl.obolibrary.org/obo/MAT_0000098 |
| T2 | 392-397 | Body_part | denotes | brain | http://purl.obolibrary.org/obo/MAT_0000098 |
| T3 | 833-838 | Body_part | denotes | brain | http://purl.obolibrary.org/obo/MAT_0000098 |
| T4 | 988-1003 | Body_part | denotes | corpus callosum | http://purl.obolibrary.org/obo/MAT_0000286 |
| T5 | 1448-1453 | Body_part | denotes | brain | http://purl.obolibrary.org/obo/MAT_0000098 |
GlyCosmos15-Sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-135 | Sentence | denotes | Age-dependent and regional heterogeneity in the long-chain base of A-series gangliosides observed in the rat brain using MALDI Imaging. |
| T2 | 136-286 | Sentence | denotes | Alterations in the long chain base of the sphingosine moiety of gangliosides have been shown to play a role in neurodevelopment and neurodegeneration. |
| T3 | 287-468 | Sentence | denotes | Indeed, the accumulation of d20:1 sphingosine has been referred to as a metabolic marker of aging in the brain, however, this remains to be shown in simple gangliosides GM2 and GM3. |
| T4 | 469-747 | Sentence | denotes | In this study, Matrix-assisted laser desorption/ionization Imaging Mass Spectrometry (MALDI IMS) was used to examine the neuroanatomical distribution of A-series gangliosides with either 18 or 20 carbon sphingosine chains (d18:1 or d20:1) in Fisher 344 rats across the lifespan. |
| T5 | 748-839 | Sentence | denotes | The ratio of d20:1/d18:1 species was determined across 11 regions of interest in the brain. |
| T6 | 840-1070 | Sentence | denotes | Interestingly, a decrease in the d20:1/d18:1 ratio for GM2 and GM3 was observed during early development with the exception of the peri-ventricular corpus callosum, where an age-dependent increase was observed for ganglioside GM3. |
| T7 | 1071-1284 | Sentence | denotes | An age-dependent increase in d20:1 species was confirmed for complex gangliosides GM1 and GD1 with the most significant increase during early development and a high degree of anatomical heterogeneity during aging. |
| T8 | 1285-1454 | Sentence | denotes | The unique neuroanatomically-specific responses of d20:1 ganglioside abundance may lead to a better understanding of regional vulnerability to damage in the aging brain. |
GlyCosmos15-Glycan
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 456-459 | Glycan | denotes | GM2 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G79389NT |
| T2 | 464-467 | Glycan | denotes | GM3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G91237TK |
| T3 | 895-898 | Glycan | denotes | GM2 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G79389NT |
| T4 | 903-906 | Glycan | denotes | GM3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G91237TK |
| T5 | 1066-1069 | Glycan | denotes | GM3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G91237TK |
| T6 | 1153-1156 | Glycan | denotes | GM1 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G48558GR |
GlyCosmos15-GlycoEpitope
| Id | Subject | Object | Predicate | Lexical cue | glycoepitope_id |
|---|---|---|---|---|---|
| T1 | 1153-1156 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | GM1 | http://www.glycoepitope.jp/epitopes/EP0050 |
NCBITAXON
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 105-108 | OrganismTaxon | denotes | rat | 10114|10116 |
| T3 | 722-726 | OrganismTaxon | denotes | rats | 10114|10116 |
Anatomy-MAT
| Id | Subject | Object | Predicate | Lexical cue | mat_id |
|---|---|---|---|---|---|
| T1 | 109-114 | Body_part | denotes | brain | http://purl.obolibrary.org/obo/MAT_0000098 |
| T2 | 392-397 | Body_part | denotes | brain | http://purl.obolibrary.org/obo/MAT_0000098 |
| T3 | 833-838 | Body_part | denotes | brain | http://purl.obolibrary.org/obo/MAT_0000098 |
| T4 | 988-1003 | Body_part | denotes | corpus callosum | http://purl.obolibrary.org/obo/MAT_0000286 |
| T5 | 1448-1453 | Body_part | denotes | brain | http://purl.obolibrary.org/obo/MAT_0000098 |
Anatomy-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 109-114 | Body_part | denotes | brain | http://purl.obolibrary.org/obo/UBERON_0000955|http://purl.obolibrary.org/obo/UBERON_6110636 |
| T3 | 392-397 | Body_part | denotes | brain | http://purl.obolibrary.org/obo/UBERON_0000955|http://purl.obolibrary.org/obo/UBERON_6110636 |
| T5 | 833-838 | Body_part | denotes | brain | http://purl.obolibrary.org/obo/UBERON_0000955|http://purl.obolibrary.org/obo/UBERON_6110636 |
| T7 | 988-1003 | Body_part | denotes | corpus callosum | http://purl.obolibrary.org/obo/UBERON_0002336 |
| T8 | 1448-1453 | Body_part | denotes | brain | http://purl.obolibrary.org/obo/UBERON_0000955|http://purl.obolibrary.org/obo/UBERON_6110636 |