PubMed:28851297
Annnotations
LitCoin-entities-OrganismTaxon-PD
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 1057-1062 | OrganismTaxon | denotes | human | NCBItxid:9606 |
| T2 | 1076-1081 | OrganismTaxon | denotes | mouse | NCBItxid:10090|NCBItxid:10088 |
| T4 | 1492-1501 | OrganismTaxon | denotes | erythroid | NCBItxid:94794 |
| T5 | 2149-2158 | OrganismTaxon | denotes | erythroid | NCBItxid:94794 |
LitCoin-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-118 | Sentence | denotes | An Aγ-globin G->A gene polymorphism associated with β039 thalassemia globin gene and high fetal hemoglobin production. |
| T2 | 119-130 | Sentence | denotes | BACKGROUND: |
| T3 | 131-323 | Sentence | denotes | Increase of the expression of γ-globin gene and high production of fetal hemoglobin (HbF) in β-thalassemia patients is widely accepted as associated with a milder or even asymptomatic disease. |
| T4 | 324-652 | Sentence | denotes | The search for HbF-associated polymorphisms (such as the XmnI, BCL11A and MYB polymorphisms) has recently gained great attention, in order to stratify β-thalassemia patients with respect to expectancy of the first transfusion, need for annual intake of blood, response to HbF inducers (the most studied of which is hydroxyurea). |
| T5 | 653-882 | Sentence | denotes | METHODS: Aγ-globin gene sequencing was performed on genomic DNA isolated from a total of 75 β-thalassemia patients, including 31 β039/β039, 33 β039/β+IVSI-110, 9 β+IVSI-110/β+IVSI-110, one β0IVSI-1/β+IVSI-6 and one β039/β+IVSI-6. |
| T6 | 883-891 | Sentence | denotes | RESULTS: |
| T7 | 892-1138 | Sentence | denotes | The results show that the rs368698783 polymorphism is present in β-thalassemia patients in the 5'UTR sequence (+25) of the Aγ-globin gene, known to affect the LYAR (human homologue of mouse Ly-1 antibody reactive clone) binding site 5'-GGTTAT-3'. |
| T8 | 1139-1308 | Sentence | denotes | This Aγ(+25 G->A) polymorphism is associated with the Gγ-globin-XmnI polymorphism and both are linked with the β039-globin gene, but not with the β+IVSI-110-globin gene. |
| T9 | 1309-1563 | Sentence | denotes | In agreement with the expectation that this mutation alters the LYAR binding activity, we found that the Aγ(+25 G->A) and Gγ-globin-XmnI polymorphisms are associated with high HbF in erythroid precursor cells isolated from β039/β039 thalassemia patients. |
| T10 | 1564-1576 | Sentence | denotes | CONCLUSIONS: |
| T11 | 1577-1988 | Sentence | denotes | As a potential explanation of our findings, we hypothesize that in β-thalassemia the Gγ-globin-XmnI/Aγ-globin-(G->A) genotype is frequently under genetic linkage with β0-thalassemia mutations, but not with the β+-thalassemia mutation here studied (i.e. β+IVSI-110) and that this genetic combination has been selected within the population of β0-thalassemia patients, due to functional association with high HbF. |
| T12 | 1989-2175 | Sentence | denotes | Here we describe the characterization of the rs368698783 (+25 G->A) polymorphism of the Aγ-globin gene associated in β039 thalassemia patients with high HbF in erythroid precursor cells. |
LitCoin-entities
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| 13386 | 3-12 | GeneOrGeneProduct | denotes | Aγ-globin | NCBIGene:3047 |
| 13387 | 13-17 | SequenceVariant | denotes | G->A | DBSNP:rs368698783 |
| 13388 | 52-75 | GeneOrGeneProduct | denotes | β039 thalassemia globin | NCBIGene:3043 |
| 13389 | 90-106 | GeneOrGeneProduct | denotes | fetal hemoglobin | NCBIGene:3040|NCBIGene:3048 |
| 13390 | 161-169 | GeneOrGeneProduct | denotes | γ-globin | NCBIGene:3047|NCBIGene:3048 |
| 13391 | 198-214 | GeneOrGeneProduct | denotes | fetal hemoglobin | NCBIGene:3040|NCBIGene:3048 |
| 13392 | 216-219 | GeneOrGeneProduct | denotes | HbF | NCBIGene:3040|NCBIGene:3048 |
| 13393 | 224-237 | DiseaseOrPhenotypicFeature | denotes | β-thalassemia | MESH:D017086 |
| 13394 | 238-246 | OrganismTaxon | denotes | patients | NCBITaxon:9606 |
| 13395 | 339-342 | GeneOrGeneProduct | denotes | HbF | NCBIGene:3040|NCBIGene:3048 |
| 13396 | 387-393 | GeneOrGeneProduct | denotes | BCL11A | NCBIGene:53335 |
| 13397 | 398-401 | GeneOrGeneProduct | denotes | MYB | NCBIGene:4602 |
| 13398 | 475-488 | DiseaseOrPhenotypicFeature | denotes | β-thalassemia | MESH:D017086 |
| 13399 | 489-497 | OrganismTaxon | denotes | patients | NCBITaxon:9606 |
| 13400 | 596-599 | GeneOrGeneProduct | denotes | HbF | NCBIGene:3040|NCBIGene:3048 |
| 13401 | 662-671 | GeneOrGeneProduct | denotes | Aγ-globin | NCBIGene:3047 |
| 13402 | 745-758 | DiseaseOrPhenotypicFeature | denotes | β-thalassemia | MESH:D017086 |
| 13403 | 759-767 | OrganismTaxon | denotes | patients | NCBITaxon:9606 |
| 13404 | 918-929 | SequenceVariant | denotes | rs368698783 | DBSNP:rs368698783 |
| 13405 | 957-970 | DiseaseOrPhenotypicFeature | denotes | β-thalassemia | MESH:D017086 |
| 13406 | 971-979 | OrganismTaxon | denotes | patients | NCBITaxon:9606 |
| 13407 | 1015-1024 | GeneOrGeneProduct | denotes | Aγ-globin | NCBIGene:3047 |
| 13408 | 1051-1055 | GeneOrGeneProduct | denotes | LYAR | NCBIGene:55646 |
| 13409 | 1057-1062 | OrganismTaxon | denotes | human | NCBITaxon:9606 |
| 13410 | 1076-1081 | OrganismTaxon | denotes | mouse | NCBITaxon:10090 |
| 13411 | 1082-1110 | GeneOrGeneProduct | denotes | Ly-1 antibody reactive clone | NCBIGene:17089 |
| 13412 | 1144-1146 | GeneOrGeneProduct | denotes | Aγ | NCBIGene:3047 |
| 13413 | 1147-1155 | SequenceVariant | denotes | +25 G->A | DBSNP:rs368698783 |
| 13414 | 1193-1202 | GeneOrGeneProduct | denotes | Gγ-globin | NCBIGene:3048 |
| 13415 | 1250-1261 | GeneOrGeneProduct | denotes | β039-globin | NCBIGene:3043 |
| 13416 | 1285-1302 | GeneOrGeneProduct | denotes | β+IVSI-110-globin | NCBIGene:3043 |
| 13417 | 1373-1377 | GeneOrGeneProduct | denotes | LYAR | NCBIGene:55646 |
| 13418 | 1414-1416 | GeneOrGeneProduct | denotes | Aγ | NCBIGene:3047 |
| 13419 | 1417-1425 | SequenceVariant | denotes | +25 G->A | DBSNP:rs368698783 |
| 13420 | 1431-1440 | GeneOrGeneProduct | denotes | Gγ-globin | NCBIGene:3048 |
| 13421 | 1485-1488 | GeneOrGeneProduct | denotes | HbF | NCBIGene:3040|NCBIGene:3048 |
| 13422 | 1532-1553 | DiseaseOrPhenotypicFeature | denotes | β039/β039 thalassemia | MESH:D017086 |
| 13423 | 1554-1562 | OrganismTaxon | denotes | patients | NCBITaxon:9606 |
| 13424 | 1644-1657 | DiseaseOrPhenotypicFeature | denotes | β-thalassemia | MESH:D017086 |
| 13425 | 1662-1671 | GeneOrGeneProduct | denotes | Gγ-globin | NCBIGene:3048 |
| 13426 | 1677-1686 | GeneOrGeneProduct | denotes | Aγ-globin | NCBIGene:3047 |
| 13427 | 1688-1692 | SequenceVariant | denotes | G->A | DBSNP:rs368698783 |
| 13428 | 1744-1758 | DiseaseOrPhenotypicFeature | denotes | β0-thalassemia | MESH:D017086 |
| 13429 | 1787-1801 | DiseaseOrPhenotypicFeature | denotes | β+-thalassemia | MESH:D017086 |
| 13430 | 1919-1933 | DiseaseOrPhenotypicFeature | denotes | β0-thalassemia | MESH:D017086 |
| 13431 | 1934-1942 | OrganismTaxon | denotes | patients | NCBITaxon:9606 |
| 13432 | 1984-1987 | GeneOrGeneProduct | denotes | HbF | NCBIGene:3040|NCBIGene:3048 |
| 13433 | 2034-2045 | SequenceVariant | denotes | rs368698783 | DBSNP:rs368698783 |
| 13434 | 2047-2055 | SequenceVariant | denotes | +25 G->A | DBSNP:rs368698783 |
| 13435 | 2077-2086 | GeneOrGeneProduct | denotes | Aγ-globin | NCBIGene:3047 |
| 13436 | 2106-2122 | DiseaseOrPhenotypicFeature | denotes | β039 thalassemia | MESH:D017086 |
| 13437 | 2123-2131 | OrganismTaxon | denotes | patients | NCBITaxon:9606 |
| 13438 | 2142-2145 | GeneOrGeneProduct | denotes | HbF | NCBIGene:3040|NCBIGene:3048 |
LitCoin_Mondo
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T1 | 57-68 | DiseaseOrPhenotypicFeature | denotes | thalassemia | 0000984 |
| T2 | 226-237 | DiseaseOrPhenotypicFeature | denotes | thalassemia | 0000984 |
| T3 | 477-488 | DiseaseOrPhenotypicFeature | denotes | thalassemia | 0000984 |
| T4 | 747-758 | DiseaseOrPhenotypicFeature | denotes | thalassemia | 0000984 |
| T5 | 959-970 | DiseaseOrPhenotypicFeature | denotes | thalassemia | 0000984 |
| T6 | 1542-1553 | DiseaseOrPhenotypicFeature | denotes | thalassemia | 0000984 |
| T7 | 1646-1657 | DiseaseOrPhenotypicFeature | denotes | thalassemia | 0000984 |
| T8 | 1747-1758 | DiseaseOrPhenotypicFeature | denotes | thalassemia | 0000984 |
| T9 | 1790-1801 | DiseaseOrPhenotypicFeature | denotes | thalassemia | 0000984 |
| T10 | 1922-1933 | DiseaseOrPhenotypicFeature | denotes | thalassemia | 0000984 |
| T11 | 2111-2122 | DiseaseOrPhenotypicFeature | denotes | thalassemia | 0000984 |
LitCoin-SeqVar
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 918-929 | SequenceVariant | denotes | rs368698783 |
| T2 | 2034-2045 | SequenceVariant | denotes | rs368698783 |
LitCoin-GeneOrGeneProduct-v0
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 6-14 | GeneOrGeneProduct | denotes | globin G |
| T2 | 69-75 | GeneOrGeneProduct | denotes | globin |
| T3 | 85-89 | GeneOrGeneProduct | denotes | high |
| T4 | 96-106 | GeneOrGeneProduct | denotes | hemoglobin |
| T5 | 107-117 | GeneOrGeneProduct | denotes | production |
| T6 | 163-169 | GeneOrGeneProduct | denotes | globin |
| T7 | 179-183 | GeneOrGeneProduct | denotes | high |
| T8 | 184-194 | GeneOrGeneProduct | denotes | production |
| T9 | 204-214 | GeneOrGeneProduct | denotes | hemoglobin |
| T10 | 297-301 | GeneOrGeneProduct | denotes | even |
| T11 | 387-393 | GeneOrGeneProduct | denotes | BCL11A |
| T12 | 398-401 | GeneOrGeneProduct | denotes | MYB |
| T13 | 437-442 | GeneOrGeneProduct | denotes | great |
| T14 | 600-608 | GeneOrGeneProduct | denotes | inducers |
| T15 | 653-660 | GeneOrGeneProduct | denotes | METHODS |
| T16 | 665-671 | GeneOrGeneProduct | denotes | globin |
| T17 | 733-738 | GeneOrGeneProduct | denotes | total |
| T18 | 987-992 | GeneOrGeneProduct | denotes | 5'UTR |
| T19 | 1018-1024 | GeneOrGeneProduct | denotes | globin |
| T20 | 1051-1055 | GeneOrGeneProduct | denotes | LYAR |
| T21 | 1063-1072 | GeneOrGeneProduct | denotes | homologue |
| T22 | 1082-1086 | GeneOrGeneProduct | denotes | Ly-1 |
| T23 | 1105-1110 | GeneOrGeneProduct | denotes | clone |
| T24 | 1112-1119 | GeneOrGeneProduct | denotes | binding |
| T25 | 1196-1202 | GeneOrGeneProduct | denotes | globin |
| T26 | 1234-1240 | GeneOrGeneProduct | denotes | linked |
| T27 | 1255-1261 | GeneOrGeneProduct | denotes | globin |
| T28 | 1296-1302 | GeneOrGeneProduct | denotes | globin |
| T29 | 1353-1361 | GeneOrGeneProduct | denotes | mutation |
| T30 | 1373-1377 | GeneOrGeneProduct | denotes | LYAR |
| T31 | 1378-1385 | GeneOrGeneProduct | denotes | binding |
| T32 | 1386-1394 | GeneOrGeneProduct | denotes | activity |
| T33 | 1434-1440 | GeneOrGeneProduct | denotes | globin |
| T34 | 1480-1484 | GeneOrGeneProduct | denotes | high |
| T35 | 1502-1511 | GeneOrGeneProduct | denotes | precursor |
| T36 | 1512-1517 | GeneOrGeneProduct | denotes | cells |
| T37 | 1611-1619 | GeneOrGeneProduct | denotes | findings |
| T38 | 1665-1671 | GeneOrGeneProduct | denotes | globin |
| T39 | 1680-1686 | GeneOrGeneProduct | denotes | globin |
| T40 | 1759-1768 | GeneOrGeneProduct | denotes | mutations |
| T41 | 1802-1810 | GeneOrGeneProduct | denotes | mutation |
| T42 | 1979-1983 | GeneOrGeneProduct | denotes | high |
| T43 | 2080-2086 | GeneOrGeneProduct | denotes | globin |
| T44 | 2137-2141 | GeneOrGeneProduct | denotes | high |
| T45 | 2159-2168 | GeneOrGeneProduct | denotes | precursor |
| T46 | 2169-2174 | GeneOrGeneProduct | denotes | cells |
LitCoin-GeneOrGeneProduct-v2
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 6-14 | GeneOrGeneProduct | denotes | globin G |
| T2 | 69-75 | GeneOrGeneProduct | denotes | globin |
| T3 | 85-89 | GeneOrGeneProduct | denotes | high |
| T4 | 96-106 | GeneOrGeneProduct | denotes | hemoglobin |
| T5 | 163-169 | GeneOrGeneProduct | denotes | globin |
| T6 | 179-183 | GeneOrGeneProduct | denotes | high |
| T7 | 204-214 | GeneOrGeneProduct | denotes | hemoglobin |
| T8 | 297-301 | GeneOrGeneProduct | denotes | even |
| T9 | 387-393 | GeneOrGeneProduct | denotes | BCL11A |
| T10 | 437-442 | GeneOrGeneProduct | denotes | great |
| T11 | 665-671 | GeneOrGeneProduct | denotes | globin |
| T12 | 987-992 | GeneOrGeneProduct | denotes | 5'UTR |
| T13 | 1018-1024 | GeneOrGeneProduct | denotes | globin |
| T14 | 1051-1055 | GeneOrGeneProduct | denotes | LYAR |
| T15 | 1063-1072 | GeneOrGeneProduct | denotes | homologue |
| T16 | 1082-1086 | GeneOrGeneProduct | denotes | Ly-1 |
| T17 | 1105-1110 | GeneOrGeneProduct | denotes | clone |
| T18 | 1112-1119 | GeneOrGeneProduct | denotes | binding |
| T19 | 1196-1202 | GeneOrGeneProduct | denotes | globin |
| T20 | 1255-1261 | GeneOrGeneProduct | denotes | globin |
| T21 | 1296-1302 | GeneOrGeneProduct | denotes | globin |
| T22 | 1373-1377 | GeneOrGeneProduct | denotes | LYAR |
| T23 | 1378-1385 | GeneOrGeneProduct | denotes | binding |
| T24 | 1434-1440 | GeneOrGeneProduct | denotes | globin |
| T25 | 1480-1484 | GeneOrGeneProduct | denotes | high |
| T26 | 1502-1511 | GeneOrGeneProduct | denotes | precursor |
| T27 | 1665-1671 | GeneOrGeneProduct | denotes | globin |
| T28 | 1680-1686 | GeneOrGeneProduct | denotes | globin |
| T29 | 1979-1983 | GeneOrGeneProduct | denotes | high |
| T30 | 2080-2086 | GeneOrGeneProduct | denotes | globin |
| T31 | 2137-2141 | GeneOrGeneProduct | denotes | high |
| T32 | 2159-2168 | GeneOrGeneProduct | denotes | precursor |
LitCoin-Disease-MeSH
| Id | Subject | Object | Predicate | Lexical cue | originalLabel |
|---|---|---|---|---|---|
| T1 | 57-68 | DiseaseOrPhenotypicFeature | denotes | thalassemia | D013789 |
| T2 | 226-237 | DiseaseOrPhenotypicFeature | denotes | thalassemia | D013789 |
| T3 | 302-322 | DiseaseOrPhenotypicFeature | denotes | asymptomatic disease | D058070 |
| T4 | 477-488 | DiseaseOrPhenotypicFeature | denotes | thalassemia | D013789 |
| T5 | 747-758 | DiseaseOrPhenotypicFeature | denotes | thalassemia | D013789 |
| T6 | 959-970 | DiseaseOrPhenotypicFeature | denotes | thalassemia | D013789 |
| T7 | 1542-1553 | DiseaseOrPhenotypicFeature | denotes | thalassemia | D013789 |
| T8 | 1646-1657 | DiseaseOrPhenotypicFeature | denotes | thalassemia | D013789 |
| T9 | 1747-1758 | DiseaseOrPhenotypicFeature | denotes | thalassemia | D013789 |
| T10 | 1790-1801 | DiseaseOrPhenotypicFeature | denotes | thalassemia | D013789 |
| T11 | 1922-1933 | DiseaseOrPhenotypicFeature | denotes | thalassemia | D013789 |
| T12 | 2111-2122 | DiseaseOrPhenotypicFeature | denotes | thalassemia | D013789 |
LitCoin-GeneOrGeneProduct-v3
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 6-14 | GeneOrGeneProduct | denotes | globin G |
| T2 | 69-75 | GeneOrGeneProduct | denotes | globin |
| T3 | 96-106 | GeneOrGeneProduct | denotes | hemoglobin |
| T4 | 163-169 | GeneOrGeneProduct | denotes | globin |
| T5 | 204-214 | GeneOrGeneProduct | denotes | hemoglobin |
| T6 | 387-393 | GeneOrGeneProduct | denotes | BCL11A |
| T7 | 437-442 | GeneOrGeneProduct | denotes | great |
| T8 | 665-671 | GeneOrGeneProduct | denotes | globin |
| T9 | 1018-1024 | GeneOrGeneProduct | denotes | globin |
| T10 | 1051-1055 | GeneOrGeneProduct | denotes | LYAR |
| T11 | 1082-1086 | GeneOrGeneProduct | denotes | Ly-1 |
| T12 | 1196-1202 | GeneOrGeneProduct | denotes | globin |
| T13 | 1255-1261 | GeneOrGeneProduct | denotes | globin |
| T14 | 1296-1302 | GeneOrGeneProduct | denotes | globin |
| T15 | 1373-1377 | GeneOrGeneProduct | denotes | LYAR |
| T16 | 1434-1440 | GeneOrGeneProduct | denotes | globin |
| T17 | 1665-1671 | GeneOrGeneProduct | denotes | globin |
| T18 | 1680-1686 | GeneOrGeneProduct | denotes | globin |
| T19 | 2080-2086 | GeneOrGeneProduct | denotes | globin |
LitCoin_Mondo_095
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T1 | 57-68 | DiseaseOrPhenotypicFeature | denotes | thalassemia | 0000984 |
| T2 | 226-237 | DiseaseOrPhenotypicFeature | denotes | thalassemia | 0000984 |
| T3 | 477-488 | DiseaseOrPhenotypicFeature | denotes | thalassemia | 0000984 |
| T4 | 747-758 | DiseaseOrPhenotypicFeature | denotes | thalassemia | 0000984 |
| T5 | 959-970 | DiseaseOrPhenotypicFeature | denotes | thalassemia | 0000984 |
| T6 | 1542-1553 | DiseaseOrPhenotypicFeature | denotes | thalassemia | 0000984 |
| T7 | 1646-1657 | DiseaseOrPhenotypicFeature | denotes | thalassemia | 0000984 |
| T8 | 1747-1758 | DiseaseOrPhenotypicFeature | denotes | thalassemia | 0000984 |
| T9 | 1790-1801 | DiseaseOrPhenotypicFeature | denotes | thalassemia | 0000984 |
| T10 | 1922-1933 | DiseaseOrPhenotypicFeature | denotes | thalassemia | 0000984 |
| T11 | 2111-2122 | DiseaseOrPhenotypicFeature | denotes | thalassemia | 0000984 |
LitCoin-MeSH-Disease-2
| Id | Subject | Object | Predicate | Lexical cue | ID: |
|---|---|---|---|---|---|
| T1 | 57-68 | DiseaseOrPhenotypicFeature | denotes | thalassemia | D013789 |
| T2 | 226-237 | DiseaseOrPhenotypicFeature | denotes | thalassemia | D013789 |
| T3 | 302-322 | DiseaseOrPhenotypicFeature | denotes | asymptomatic disease | D058070 |
| T4 | 477-488 | DiseaseOrPhenotypicFeature | denotes | thalassemia | D013789 |
| T5 | 747-758 | DiseaseOrPhenotypicFeature | denotes | thalassemia | D013789 |
| T6 | 959-970 | DiseaseOrPhenotypicFeature | denotes | thalassemia | D013789 |
| T7 | 1542-1553 | DiseaseOrPhenotypicFeature | denotes | thalassemia | D013789 |
| T8 | 1646-1657 | DiseaseOrPhenotypicFeature | denotes | thalassemia | D013789 |
| T9 | 1747-1758 | DiseaseOrPhenotypicFeature | denotes | thalassemia | D013789 |
| T10 | 1790-1801 | DiseaseOrPhenotypicFeature | denotes | thalassemia | D013789 |
| T11 | 1922-1933 | DiseaseOrPhenotypicFeature | denotes | thalassemia | D013789 |
| T12 | 2111-2122 | DiseaseOrPhenotypicFeature | denotes | thalassemia | D013789 |
LitCoin-MONDO_bioort2019
| Id | Subject | Object | Predicate | Lexical cue | #label |
|---|---|---|---|---|---|
| T1 | 57-68 | DiseaseOrPhenotypicFeature | denotes | thalassemia | D013789 |
| T2 | 226-237 | DiseaseOrPhenotypicFeature | denotes | thalassemia | D013789 |
| T3 | 302-322 | DiseaseOrPhenotypicFeature | denotes | asymptomatic disease | D058070 |
| T4 | 477-488 | DiseaseOrPhenotypicFeature | denotes | thalassemia | D013789 |
| T5 | 747-758 | DiseaseOrPhenotypicFeature | denotes | thalassemia | D013789 |
| T6 | 959-970 | DiseaseOrPhenotypicFeature | denotes | thalassemia | D013789 |
| T7 | 1542-1553 | DiseaseOrPhenotypicFeature | denotes | thalassemia | D013789 |
| T8 | 1646-1657 | DiseaseOrPhenotypicFeature | denotes | thalassemia | D013789 |
| T9 | 1747-1758 | DiseaseOrPhenotypicFeature | denotes | thalassemia | D013789 |
| T10 | 1790-1801 | DiseaseOrPhenotypicFeature | denotes | thalassemia | D013789 |
| T11 | 1922-1933 | DiseaseOrPhenotypicFeature | denotes | thalassemia | D013789 |
| T12 | 2111-2122 | DiseaseOrPhenotypicFeature | denotes | thalassemia | D013789 |
LitCoin-Chemical-MeSH-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | ID: |
|---|---|---|---|---|---|
| T1 | 6-12 | ChemicalEntity | denotes | globin | http://purl.obolibrary.org/obo/CHEBI_5386 |
| T2 | 69-75 | ChemicalEntity | denotes | globin | http://purl.obolibrary.org/obo/CHEBI_5386 |
| T3 | 96-106 | ChemicalEntity | denotes | hemoglobin | http://purl.obolibrary.org/obo/CHEBI_35143 |
| T4 | 163-169 | ChemicalEntity | denotes | globin | http://purl.obolibrary.org/obo/CHEBI_5386 |
| T5 | 204-214 | ChemicalEntity | denotes | hemoglobin | http://purl.obolibrary.org/obo/CHEBI_35143 |
| T6 | 639-650 | ChemicalEntity | denotes | hydroxyurea | D006918|http://purl.obolibrary.org/obo/CHEBI_44423 |
| T8 | 665-671 | ChemicalEntity | denotes | globin | http://purl.obolibrary.org/obo/CHEBI_5386 |
| T9 | 1018-1024 | ChemicalEntity | denotes | globin | http://purl.obolibrary.org/obo/CHEBI_5386 |
| T10 | 1196-1202 | ChemicalEntity | denotes | globin | http://purl.obolibrary.org/obo/CHEBI_5386 |
| T11 | 1255-1261 | ChemicalEntity | denotes | globin | http://purl.obolibrary.org/obo/CHEBI_5386 |
| T12 | 1296-1302 | ChemicalEntity | denotes | globin | http://purl.obolibrary.org/obo/CHEBI_5386 |
| T13 | 1434-1440 | ChemicalEntity | denotes | globin | http://purl.obolibrary.org/obo/CHEBI_5386 |
| T14 | 1665-1671 | ChemicalEntity | denotes | globin | http://purl.obolibrary.org/obo/CHEBI_5386 |
| T15 | 1680-1686 | ChemicalEntity | denotes | globin | http://purl.obolibrary.org/obo/CHEBI_5386 |
| T16 | 2080-2086 | ChemicalEntity | denotes | globin | http://purl.obolibrary.org/obo/CHEBI_5386 |
LitCoin-NCBITaxon-2
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 238-246 | OrganismTaxon | denotes | patients |
| T2 | 489-497 | OrganismTaxon | denotes | patients |
| T3 | 759-767 | OrganismTaxon | denotes | patients |
| T4 | 971-979 | OrganismTaxon | denotes | patients |
| T5 | 1057-1062 | OrganismTaxon | denotes | human |
| T6 | 1076-1081 | OrganismTaxon | denotes | mouse |
| T7 | 1492-1501 | OrganismTaxon | denotes | erythroid |
| T8 | 1554-1562 | OrganismTaxon | denotes | patients |
| T9 | 1934-1942 | OrganismTaxon | denotes | patients |
| T10 | 2123-2131 | OrganismTaxon | denotes | patients |
| T11 | 2149-2158 | OrganismTaxon | denotes | erythroid |
LitCoin-training-merged
| Id | Subject | Object | Predicate | Lexical cue | #label | ID: |
|---|---|---|---|---|---|---|
| T16 | 2080-2086 | ChemicalEntity | denotes | globin | http://purl.obolibrary.org/obo/CHEBI_5386 | |
| T15 | 1680-1686 | ChemicalEntity | denotes | globin | http://purl.obolibrary.org/obo/CHEBI_5386 | |
| T14 | 1665-1671 | ChemicalEntity | denotes | globin | http://purl.obolibrary.org/obo/CHEBI_5386 | |
| T13 | 1434-1440 | ChemicalEntity | denotes | globin | http://purl.obolibrary.org/obo/CHEBI_5386 | |
| T12 | 1296-1302 | ChemicalEntity | denotes | globin | http://purl.obolibrary.org/obo/CHEBI_5386 | |
| T11 | 1255-1261 | ChemicalEntity | denotes | globin | http://purl.obolibrary.org/obo/CHEBI_5386 | |
| T10 | 1196-1202 | ChemicalEntity | denotes | globin | http://purl.obolibrary.org/obo/CHEBI_5386 | |
| T9 | 1018-1024 | ChemicalEntity | denotes | globin | http://purl.obolibrary.org/obo/CHEBI_5386 | |
| T8 | 665-671 | ChemicalEntity | denotes | globin | http://purl.obolibrary.org/obo/CHEBI_5386 | |
| T6 | 639-650 | ChemicalEntity | denotes | hydroxyurea | http://purl.obolibrary.org/obo/CHEBI_44423|D006918 | |
| T5 | 204-214 | ChemicalEntity | denotes | hemoglobin | http://purl.obolibrary.org/obo/CHEBI_35143 | |
| T4 | 163-169 | ChemicalEntity | denotes | globin | http://purl.obolibrary.org/obo/CHEBI_5386 | |
| T3 | 96-106 | ChemicalEntity | denotes | hemoglobin | http://purl.obolibrary.org/obo/CHEBI_35143 | |
| T2 | 69-75 | ChemicalEntity | denotes | globin | http://purl.obolibrary.org/obo/CHEBI_5386 | |
| T1 | 6-12 | ChemicalEntity | denotes | globin | http://purl.obolibrary.org/obo/CHEBI_5386 | |
| T19 | 2080-2086 | GeneOrGeneProduct | denotes | globin | ||
| T18 | 1680-1686 | GeneOrGeneProduct | denotes | globin | ||
| T17 | 1665-1671 | GeneOrGeneProduct | denotes | globin | ||
| T99797 | 1434-1440 | GeneOrGeneProduct | denotes | globin | ||
| T39797 | 1373-1377 | GeneOrGeneProduct | denotes | LYAR | ||
| T50008 | 1296-1302 | GeneOrGeneProduct | denotes | globin | ||
| T95831 | 1255-1261 | GeneOrGeneProduct | denotes | globin | ||
| T41629 | 1196-1202 | GeneOrGeneProduct | denotes | globin | ||
| T65060 | 1082-1086 | GeneOrGeneProduct | denotes | Ly-1 | ||
| T78934 | 1051-1055 | GeneOrGeneProduct | denotes | LYAR | ||
| T74341 | 1018-1024 | GeneOrGeneProduct | denotes | globin | ||
| T33480 | 665-671 | GeneOrGeneProduct | denotes | globin | ||
| T7 | 437-442 | GeneOrGeneProduct | denotes | great | ||
| T96833 | 387-393 | GeneOrGeneProduct | denotes | BCL11A | ||
| T19660 | 204-214 | GeneOrGeneProduct | denotes | hemoglobin | ||
| T54702 | 163-169 | GeneOrGeneProduct | denotes | globin | ||
| T41288 | 96-106 | GeneOrGeneProduct | denotes | hemoglobin | ||
| T6870 | 69-75 | GeneOrGeneProduct | denotes | globin | ||
| T23870 | 6-14 | GeneOrGeneProduct | denotes | globin G | ||
| T77424 | 2111-2122 | DiseaseOrPhenotypicFeature | denotes | thalassemia | D013789 | |
| T2718 | 1922-1933 | DiseaseOrPhenotypicFeature | denotes | thalassemia | D013789 | |
| T26727 | 1790-1801 | DiseaseOrPhenotypicFeature | denotes | thalassemia | D013789 | |
| T67623 | 1747-1758 | DiseaseOrPhenotypicFeature | denotes | thalassemia | D013789 | |
| T11158 | 1646-1657 | DiseaseOrPhenotypicFeature | denotes | thalassemia | D013789 | |
| T63593 | 1542-1553 | DiseaseOrPhenotypicFeature | denotes | thalassemia | D013789 | |
| T40396 | 959-970 | DiseaseOrPhenotypicFeature | denotes | thalassemia | D013789 | |
| T80003 | 747-758 | DiseaseOrPhenotypicFeature | denotes | thalassemia | D013789 | |
| T40449 | 477-488 | DiseaseOrPhenotypicFeature | denotes | thalassemia | D013789 | |
| T55322 | 302-322 | DiseaseOrPhenotypicFeature | denotes | asymptomatic disease | D058070 | |
| T94269 | 226-237 | DiseaseOrPhenotypicFeature | denotes | thalassemia | D013789 | |
| T81974 | 57-68 | DiseaseOrPhenotypicFeature | denotes | thalassemia | D013789 | |
| T39335 | 2149-2158 | OrganismTaxon | denotes | erythroid | ||
| T45745 | 2123-2131 | OrganismTaxon | denotes | patients | ||
| T21987 | 1934-1942 | OrganismTaxon | denotes | patients | ||
| T45273 | 1554-1562 | OrganismTaxon | denotes | patients | ||
| T50017 | 1492-1501 | OrganismTaxon | denotes | erythroid | ||
| T87693 | 1076-1081 | OrganismTaxon | denotes | mouse | ||
| T70787 | 1057-1062 | OrganismTaxon | denotes | human | ||
| T93452 | 971-979 | OrganismTaxon | denotes | patients | ||
| T47779 | 759-767 | OrganismTaxon | denotes | patients | ||
| T1147 | 489-497 | OrganismTaxon | denotes | patients | ||
| T67950 | 238-246 | OrganismTaxon | denotes | patients | ||
| T79024 | 2034-2045 | SequenceVariant | denotes | rs368698783 | ||
| T34218 | 918-929 | SequenceVariant | denotes | rs368698783 |