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sentences

Id Subject Object Predicate Lexical cue
T1 0-105 Sentence denotes Rat pheochromocytoma tyrosine hydroxylase is phosphorylated on serine 40 by an associated protein kinase.
T2 106-386 Sentence denotes Tyrosine hydroxylase, a key enzyme in the biosynthesis of catecholamines, was previously shown to be phosphorylated on four distinct serine residues in PC12 cell cultures, each one being specific for the kinase system involved (McTigue, M., Cremins, J., and Halegoua, S. (1985) J.
T3 387-392 Sentence denotes Biol.
T4 393-398 Sentence denotes Chem.
T5 399-415 Sentence denotes 260, 9047-9056).
T6 416-554 Sentence denotes A cAMP- and Ca2+-independent protein kinase was found to be associated with tyrosine hydroxylase purified from rat pheochromocytoma tumor.
T7 555-726 Sentence denotes The use of this activity and the availability of a large amount of purified tyrosine hydroxylase allowed identification of the site phosphorylated by this kinase activity.
T8 727-896 Sentence denotes A peptide of 1.5 kDa (about 12 residues long), carrying the phosphorylation site, was released from 32P-labeled tyrosine hydroxylase by limited proteolysis with trypsin.
T9 897-1024 Sentence denotes This peptide was isolated from trypsinized tyrosine hydroxylase by sequential gel filtration and ion exchange chromatographies.
T10 1025-1142 Sentence denotes Analysis by thin layer chromatography of an acid hydrolysate of the peptide revealed that it contained phosphoserine.
T11 1143-1318 Sentence denotes The sequence determination of the peptide showed that it corresponded to the residues 38-45 in the tyrosine hydroxylase primary structure (Arg-Gln-Ser(P)-Leu-Ile-Glu-Asp-Ala).
T12 1319-1483 Sentence denotes Thus, the associated kinase phosphorylated Ser-40, one of the phosphorylation sites for the cAMP-dependent protein kinase also found in rat pheochromocytoma tumors.
T13 1484-1583 Sentence denotes These results are compared to those recently appearing in a report by Campbell et al. (Campbell, D.
T14 1584-1598 Sentence denotes G., Hardie, D.
T15 1599-1618 Sentence denotes G., and Vulliet, P.
T16 1619-1631 Sentence denotes R. (1986) J.
T17 1632-1637 Sentence denotes Biol.
T18 1638-1643 Sentence denotes Chem.
T19 1644-1662 Sentence denotes 261, 10489-10492).
T1 0-105 Sentence denotes Rat pheochromocytoma tyrosine hydroxylase is phosphorylated on serine 40 by an associated protein kinase.
T2 106-386 Sentence denotes Tyrosine hydroxylase, a key enzyme in the biosynthesis of catecholamines, was previously shown to be phosphorylated on four distinct serine residues in PC12 cell cultures, each one being specific for the kinase system involved (McTigue, M., Cremins, J., and Halegoua, S. (1985) J.
T3 387-392 Sentence denotes Biol.
T4 393-398 Sentence denotes Chem.
T5 399-415 Sentence denotes 260, 9047-9056).
T6 416-554 Sentence denotes A cAMP- and Ca2+-independent protein kinase was found to be associated with tyrosine hydroxylase purified from rat pheochromocytoma tumor.
T7 555-726 Sentence denotes The use of this activity and the availability of a large amount of purified tyrosine hydroxylase allowed identification of the site phosphorylated by this kinase activity.
T8 727-896 Sentence denotes A peptide of 1.5 kDa (about 12 residues long), carrying the phosphorylation site, was released from 32P-labeled tyrosine hydroxylase by limited proteolysis with trypsin.
T9 897-1024 Sentence denotes This peptide was isolated from trypsinized tyrosine hydroxylase by sequential gel filtration and ion exchange chromatographies.
T10 1025-1142 Sentence denotes Analysis by thin layer chromatography of an acid hydrolysate of the peptide revealed that it contained phosphoserine.
T11 1143-1318 Sentence denotes The sequence determination of the peptide showed that it corresponded to the residues 38-45 in the tyrosine hydroxylase primary structure (Arg-Gln-Ser(P)-Leu-Ile-Glu-Asp-Ala).
T12 1319-1483 Sentence denotes Thus, the associated kinase phosphorylated Ser-40, one of the phosphorylation sites for the cAMP-dependent protein kinase also found in rat pheochromocytoma tumors.
T13 1484-1583 Sentence denotes These results are compared to those recently appearing in a report by Campbell et al. (Campbell, D.
T14 1584-1598 Sentence denotes G., Hardie, D.
T15 1599-1618 Sentence denotes G., and Vulliet, P.
T16 1619-1631 Sentence denotes R. (1986) J.
T17 1632-1637 Sentence denotes Biol.
T18 1638-1643 Sentence denotes Chem.
T19 1644-1662 Sentence denotes 261, 10489-10492).

PubmedHPO

Id Subject Object Predicate Lexical cue
T1 531-547 HP_0002666 denotes pheochromocytoma
T2 548-553 HP_0002664 denotes tumor
T3 1459-1475 HP_0002666 denotes pheochromocytoma
T4 1476-1482 HP_0002664 denotes tumors

HP-phenotype

Id Subject Object Predicate Lexical cue hp_id
T1 4-20 Phenotype denotes pheochromocytoma HP:0002666
T2 531-547 Phenotype denotes pheochromocytoma HP:0002666
T3 548-553 Phenotype denotes tumor HP:0002664
T4 1459-1475 Phenotype denotes pheochromocytoma HP:0002666

mondo_disease

Id Subject Object Predicate Lexical cue mondo_id
T1 4-20 Disease denotes pheochromocytoma http://purl.obolibrary.org/obo/MONDO_0004974|http://purl.obolibrary.org/obo/MONDO_0008233
T3 531-547 Disease denotes pheochromocytoma http://purl.obolibrary.org/obo/MONDO_0004974|http://purl.obolibrary.org/obo/MONDO_0008233
T5 548-553 Disease denotes tumor http://purl.obolibrary.org/obo/MONDO_0005070
T6 1459-1475 Disease denotes pheochromocytoma http://purl.obolibrary.org/obo/MONDO_0004974|http://purl.obolibrary.org/obo/MONDO_0008233
T8 1476-1482 Disease denotes tumors http://purl.obolibrary.org/obo/MONDO_0005070

NCBITAXON

Id Subject Object Predicate Lexical cue db_id
T1 527-530 OrganismTaxon denotes rat 10114|10116
T3 1455-1458 OrganismTaxon denotes rat 10114|10116

Anatomy-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 1042-1047 Body_part denotes layer http://purl.obolibrary.org/obo/UBERON_0000119|http://purl.obolibrary.org/obo/UBERON_0022303