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Inflammaging

Id Subject Object Predicate Lexical cue
T1 0-323 Sentence denotes [NOD2 gene mutation in Moroccan patients with Crohn's disease: prevalence, genotypic study and correlation of NOD2 gene mutation with the phenotype of Crohn's disease].Mutation du gène NOD2 chez les patients marocains atteints de la maladie de Crohn: prévalence, étude génotypique et corrélation au phénotype de la maladie.
T2 324-526 Sentence denotes The aim of this study was to determine the prevalence of NOD2/CARD15 gene mutations in a group of Moroccan patients with Crohn's disease and to study its correlation with genotype-phenotypic expression.
T3 527-604 Sentence denotes We conducted a cross-sectional case-control study over a period of 16 months.
T4 605-732 Sentence denotes 101 patients with Crohn's disease were enrolled between January 2012 and April 2013 as well as a control group of 107 patients.
T5 733-843 Sentence denotes We performed a genetic analysis to identify 3 NOD2 gene variants: p.Arg702Trp, p.Gly908Arg and p.Leu1007fsins.
T6 844-932 Sentence denotes Then we conducted a study of the correlation between genotype and phenotypic expression.
T7 933-1100 Sentence denotes The genetic analysis of patients with Crohn's disease highlighted the presence of NOD2 mutation in 14 patients (13.77%) versus 7 patients (6.53%) in the control group.
T8 1101-1297 Sentence denotes The study of the frequency of different alleles showed p.Gly908Arg mutation in 6.43%, p.Leu1007fsins in 0.99% and p.Arg702Trp in 0.49% versus 2.80%, 0% and 0.46% in the control group respectively.
T9 1298-1592 Sentence denotes The study of the correlation between genotype and phenotypic expression showed that CARD15 mutation is associated with ileocecal Crohn's disease, with fistulizing and stenosing behavior in Crohn's disease as well as with severe evolution and frequent recourse to surgery and immunosuppressants.
T10 1593-1659 Sentence denotes The prevalence of NOD2/ CARD15 mutation in our case series is low.
T11 1660-1716 Sentence denotes This mutation is correlated with severe Crohn's disease.
T1 0-323 Sentence denotes [NOD2 gene mutation in Moroccan patients with Crohn's disease: prevalence, genotypic study and correlation of NOD2 gene mutation with the phenotype of Crohn's disease].Mutation du gène NOD2 chez les patients marocains atteints de la maladie de Crohn: prévalence, étude génotypique et corrélation au phénotype de la maladie.
T2 324-526 Sentence denotes The aim of this study was to determine the prevalence of NOD2/CARD15 gene mutations in a group of Moroccan patients with Crohn's disease and to study its correlation with genotype-phenotypic expression.
T3 527-604 Sentence denotes We conducted a cross-sectional case-control study over a period of 16 months.
T4 605-732 Sentence denotes 101 patients with Crohn's disease were enrolled between January 2012 and April 2013 as well as a control group of 107 patients.
T5 733-843 Sentence denotes We performed a genetic analysis to identify 3 NOD2 gene variants: p.Arg702Trp, p.Gly908Arg and p.Leu1007fsins.
T6 844-932 Sentence denotes Then we conducted a study of the correlation between genotype and phenotypic expression.
T7 933-1100 Sentence denotes The genetic analysis of patients with Crohn's disease highlighted the presence of NOD2 mutation in 14 patients (13.77%) versus 7 patients (6.53%) in the control group.
T8 1101-1297 Sentence denotes The study of the frequency of different alleles showed p.Gly908Arg mutation in 6.43%, p.Leu1007fsins in 0.99% and p.Arg702Trp in 0.49% versus 2.80%, 0% and 0.46% in the control group respectively.
T9 1298-1592 Sentence denotes The study of the correlation between genotype and phenotypic expression showed that CARD15 mutation is associated with ileocecal Crohn's disease, with fistulizing and stenosing behavior in Crohn's disease as well as with severe evolution and frequent recourse to surgery and immunosuppressants.
T10 1593-1659 Sentence denotes The prevalence of NOD2/ CARD15 mutation in our case series is low.
T11 1660-1716 Sentence denotes This mutation is correlated with severe Crohn's disease.