PubMed:28777492
Annnotations
Inflammaging
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 0-114 | Sentence | denotes | Gankyrin induces STAT3 activation in tumour microenvironment and sorafenib resistance in hepatocellular carcinoma. |
T2 | 115-203 | Sentence | denotes | Most hepatocellular carcinomas (HCCs) develop as a result of chronic liver inflammation. |
T3 | 204-313 | Sentence | denotes | We have shown that the oncoprotein gankyrin is critical for inflammation-induced tumourigenesis in the colon. |
T4 | 314-414 | Sentence | denotes | Although the in vitro function of gankyrin is well known, its role in vivo remains to be elucidated. |
T5 | 415-668 | Sentence | denotes | We investigated the effect of gankyrin in tumour microenvironment of mice with liver parenchymal cell-specific gankyrin ablation (Alb-Cre;gankyrin(f/f) ) and gankyrin deletion both in liver parenchymal and non-parenchymal cells (Mx1-Cre;gankyrin(f/f) ). |
T6 | 669-721 | Sentence | denotes | Gankyrin upregulates VEGF expression in tumor cells. |
T7 | 722-968 | Sentence | denotes | Gankyrin binds to Src homology 2 domain-containing protein tyrosine phosphatase-1 (SHP-1), mainly expressed in liver non-parenchymal cells, resulting in phosphorylation and activation of signal transducer and activator of transcription 3 (STAT3). |
T8 | 969-1238 | Sentence | denotes | Gankyrin deficiency in non-parenchymal cells, but not in parenchymal cells, reduced STAT3 activity, interleukin (IL)-6 production, and cancer stem cell marker (Bmi1 and epithelial cell adhesion molecule [EpCAM]) expression, leading to attenuated tumourigenic potential. |
T9 | 1239-1308 | Sentence | denotes | Chronic inflammation enhances gankyrin expression in the human liver. |
T10 | 1309-1467 | Sentence | denotes | Gankyrin expression in the tumour microenvironment is negatively correlated with progression-free survival in patients undergoing sorafenib treatment for HCC. |
T11 | 1468-1651 | Sentence | denotes | Thus, gankyrin appears to play a critical oncogenic function in tumour microenvironment and may be a potential target for developing therapeutic and preventive strategies against HCC. |
T12 | 1652-1691 | Sentence | denotes | This article is protected by copyright. |
T13 | 1692-1712 | Sentence | denotes | All rights reserved. |
T1 | 0-114 | Sentence | denotes | Gankyrin induces STAT3 activation in tumour microenvironment and sorafenib resistance in hepatocellular carcinoma. |
T2 | 115-203 | Sentence | denotes | Most hepatocellular carcinomas (HCCs) develop as a result of chronic liver inflammation. |
T3 | 204-313 | Sentence | denotes | We have shown that the oncoprotein gankyrin is critical for inflammation-induced tumourigenesis in the colon. |
T4 | 314-414 | Sentence | denotes | Although the in vitro function of gankyrin is well known, its role in vivo remains to be elucidated. |
T5 | 415-668 | Sentence | denotes | We investigated the effect of gankyrin in tumour microenvironment of mice with liver parenchymal cell-specific gankyrin ablation (Alb-Cre;gankyrin(f/f) ) and gankyrin deletion both in liver parenchymal and non-parenchymal cells (Mx1-Cre;gankyrin(f/f) ). |
T6 | 669-721 | Sentence | denotes | Gankyrin upregulates VEGF expression in tumor cells. |
T7 | 722-968 | Sentence | denotes | Gankyrin binds to Src homology 2 domain-containing protein tyrosine phosphatase-1 (SHP-1), mainly expressed in liver non-parenchymal cells, resulting in phosphorylation and activation of signal transducer and activator of transcription 3 (STAT3). |
T8 | 969-1238 | Sentence | denotes | Gankyrin deficiency in non-parenchymal cells, but not in parenchymal cells, reduced STAT3 activity, interleukin (IL)-6 production, and cancer stem cell marker (Bmi1 and epithelial cell adhesion molecule [EpCAM]) expression, leading to attenuated tumourigenic potential. |
T9 | 1239-1308 | Sentence | denotes | Chronic inflammation enhances gankyrin expression in the human liver. |
T10 | 1309-1467 | Sentence | denotes | Gankyrin expression in the tumour microenvironment is negatively correlated with progression-free survival in patients undergoing sorafenib treatment for HCC. |
T11 | 1468-1651 | Sentence | denotes | Thus, gankyrin appears to play a critical oncogenic function in tumour microenvironment and may be a potential target for developing therapeutic and preventive strategies against HCC. |
T12 | 1652-1691 | Sentence | denotes | This article is protected by copyright. |
T13 | 1692-1712 | Sentence | denotes | All rights reserved. |
LitCoin-entities-OrganismTaxon-PD
Id | Subject | Object | Predicate | Lexical cue | db_id |
---|---|---|---|---|---|
T1 | 484-488 | OrganismTaxon | denotes | mice | NCBItxid:10095|NCBItxid:10088 |
T3 | 1296-1301 | OrganismTaxon | denotes | human | NCBItxid:9606 |
LitCoin-sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 0-114 | Sentence | denotes | Gankyrin induces STAT3 activation in tumour microenvironment and sorafenib resistance in hepatocellular carcinoma. |
T2 | 115-203 | Sentence | denotes | Most hepatocellular carcinomas (HCCs) develop as a result of chronic liver inflammation. |
T3 | 204-313 | Sentence | denotes | We have shown that the oncoprotein gankyrin is critical for inflammation-induced tumourigenesis in the colon. |
T4 | 314-414 | Sentence | denotes | Although the in vitro function of gankyrin is well known, its role in vivo remains to be elucidated. |
T5 | 415-668 | Sentence | denotes | We investigated the effect of gankyrin in tumour microenvironment of mice with liver parenchymal cell-specific gankyrin ablation (Alb-Cre;gankyrin(f/f) ) and gankyrin deletion both in liver parenchymal and non-parenchymal cells (Mx1-Cre;gankyrin(f/f) ). |
T6 | 669-721 | Sentence | denotes | Gankyrin upregulates VEGF expression in tumor cells. |
T7 | 722-968 | Sentence | denotes | Gankyrin binds to Src homology 2 domain-containing protein tyrosine phosphatase-1 (SHP-1), mainly expressed in liver non-parenchymal cells, resulting in phosphorylation and activation of signal transducer and activator of transcription 3 (STAT3). |
T8 | 969-1238 | Sentence | denotes | Gankyrin deficiency in non-parenchymal cells, but not in parenchymal cells, reduced STAT3 activity, interleukin (IL)-6 production, and cancer stem cell marker (Bmi1 and epithelial cell adhesion molecule [EpCAM]) expression, leading to attenuated tumourigenic potential. |
T9 | 1239-1308 | Sentence | denotes | Chronic inflammation enhances gankyrin expression in the human liver. |
T10 | 1309-1467 | Sentence | denotes | Gankyrin expression in the tumour microenvironment is negatively correlated with progression-free survival in patients undergoing sorafenib treatment for HCC. |
T11 | 1468-1651 | Sentence | denotes | Thus, gankyrin appears to play a critical oncogenic function in tumour microenvironment and may be a potential target for developing therapeutic and preventive strategies against HCC. |
T12 | 1652-1691 | Sentence | denotes | This article is protected by copyright. |
T13 | 1692-1712 | Sentence | denotes | All rights reserved. |
LitCoin-entities
Id | Subject | Object | Predicate | Lexical cue | db_id |
---|---|---|---|---|---|
13250 | 0-8 | GeneOrGeneProduct | denotes | Gankyrin | NCBIGene:53380 |
13251 | 17-22 | GeneOrGeneProduct | denotes | STAT3 | NCBIGene:20848 |
13252 | 37-43 | DiseaseOrPhenotypicFeature | denotes | tumour | MESH:D009369 |
13253 | 65-74 | ChemicalEntity | denotes | sorafenib | MESH:D000077157 |
13254 | 89-113 | DiseaseOrPhenotypicFeature | denotes | hepatocellular carcinoma | MESH:D006528 |
13255 | 120-145 | DiseaseOrPhenotypicFeature | denotes | hepatocellular carcinomas | MESH:D006528 |
13256 | 147-150 | DiseaseOrPhenotypicFeature | denotes | HCC | MESH:D006528 |
13257 | 176-202 | DiseaseOrPhenotypicFeature | denotes | chronic liver inflammation | MESH:D007249 |
13258 | 227-238 | GeneOrGeneProduct | denotes | oncoprotein | NCBIGene:53380 |
13259 | 239-247 | GeneOrGeneProduct | denotes | gankyrin | NCBIGene:53380 |
13260 | 264-276 | DiseaseOrPhenotypicFeature | denotes | inflammation | MESH:D007249 |
13261 | 285-299 | DiseaseOrPhenotypicFeature | denotes | tumourigenesis | MESH:D009369 |
13262 | 348-356 | GeneOrGeneProduct | denotes | gankyrin | NCBIGene:5716 |
13263 | 445-453 | GeneOrGeneProduct | denotes | gankyrin | NCBIGene:53380 |
13264 | 458-463 | DiseaseOrPhenotypicFeature | denotes | umour | MESH:D009369 |
13265 | 484-488 | OrganismTaxon | denotes | mice | NCBITaxon:10090 |
13266 | 526-534 | GeneOrGeneProduct | denotes | gankyrin | NCBIGene:53380 |
13267 | 545-548 | GeneOrGeneProduct | denotes | Alb | NCBIGene:11657 |
13268 | 553-561 | GeneOrGeneProduct | denotes | gankyrin | NCBIGene:53380 |
13269 | 573-581 | GeneOrGeneProduct | denotes | gankyrin | NCBIGene:53380 |
13270 | 644-647 | GeneOrGeneProduct | denotes | Mx1 | NCBIGene:17857 |
13271 | 652-660 | GeneOrGeneProduct | denotes | gankyrin | NCBIGene:53380 |
13272 | 669-677 | GeneOrGeneProduct | denotes | Gankyrin | NCBIGene:5716 |
13273 | 690-694 | GeneOrGeneProduct | denotes | VEGF | NCBIGene:22339 |
13274 | 709-714 | DiseaseOrPhenotypicFeature | denotes | tumor | MESH:D009369 |
13275 | 722-730 | GeneOrGeneProduct | denotes | Gankyrin | NCBIGene:53380 |
13276 | 740-803 | GeneOrGeneProduct | denotes | Src homology 2 domain-containing protein tyrosine phosphatase-1 | NCBIGene:15170 |
13277 | 805-810 | GeneOrGeneProduct | denotes | SHP-1 | NCBIGene:15170 |
13278 | 909-959 | GeneOrGeneProduct | denotes | signal transducer and activator of transcription 3 | NCBIGene:20848 |
13279 | 961-966 | GeneOrGeneProduct | denotes | STAT3 | NCBIGene:20848 |
13280 | 969-977 | GeneOrGeneProduct | denotes | Gankyrin | NCBIGene:53380 |
13281 | 1053-1058 | GeneOrGeneProduct | denotes | STAT3 | NCBIGene:20848 |
13282 | 1069-1087 | GeneOrGeneProduct | denotes | interleukin (IL)-6 | NCBIGene:16193 |
13283 | 1104-1110 | DiseaseOrPhenotypicFeature | denotes | cancer | MESH:D009369 |
13284 | 1129-1133 | GeneOrGeneProduct | denotes | Bmi1 | NCBIGene:12151 |
13285 | 1138-1171 | GeneOrGeneProduct | denotes | epithelial cell adhesion molecule | NCBIGene:17075 |
13286 | 1173-1178 | GeneOrGeneProduct | denotes | EpCAM | NCBIGene:17075 |
13287 | 1215-1227 | DiseaseOrPhenotypicFeature | denotes | tumourigenic | MESH:D009369 |
13288 | 1239-1259 | DiseaseOrPhenotypicFeature | denotes | Chronic inflammation | MESH:D007249 |
13289 | 1269-1277 | GeneOrGeneProduct | denotes | gankyrin | NCBIGene:5716 |
13290 | 1296-1301 | OrganismTaxon | denotes | human | NCBITaxon:9606 |
13291 | 1309-1317 | GeneOrGeneProduct | denotes | Gankyrin | NCBIGene:5716 |
13292 | 1336-1342 | DiseaseOrPhenotypicFeature | denotes | tumour | MESH:D009369 |
13293 | 1419-1427 | OrganismTaxon | denotes | patients | NCBITaxon:9606 |
13294 | 1439-1448 | ChemicalEntity | denotes | sorafenib | MESH:D000077157 |
13295 | 1463-1466 | DiseaseOrPhenotypicFeature | denotes | HCC | MESH:D006528 |
13296 | 1474-1482 | GeneOrGeneProduct | denotes | gankyrin | NCBIGene:53380 |
13297 | 1532-1538 | DiseaseOrPhenotypicFeature | denotes | tumour | MESH:D009369 |
13298 | 1647-1650 | DiseaseOrPhenotypicFeature | denotes | HCC | MESH:D006528 |
LitCoin_Mondo
Id | Subject | Object | Predicate | Lexical cue | mondo_id |
---|---|---|---|---|---|
T1 | 89-113 | DiseaseOrPhenotypicFeature | denotes | hepatocellular carcinoma | 0007256 |
T2 | 104-113 | DiseaseOrPhenotypicFeature | denotes | carcinoma | 0004993 |
T3 | 120-145 | DiseaseOrPhenotypicFeature | denotes | hepatocellular carcinomas | 0007256 |
T4 | 1104-1110 | DiseaseOrPhenotypicFeature | denotes | cancer | 0004992 |
LitCoin-GeneOrGeneProduct-v0
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 0-8 | GeneOrGeneProduct | denotes | Gankyrin |
T2 | 9-16 | GeneOrGeneProduct | denotes | induces |
T3 | 17-22 | GeneOrGeneProduct | denotes | STAT3 |
T4 | 23-33 | GeneOrGeneProduct | denotes | activation |
T5 | 147-151 | GeneOrGeneProduct | denotes | HCCs |
T6 | 184-189 | GeneOrGeneProduct | denotes | liver |
T7 | 239-247 | GeneOrGeneProduct | denotes | gankyrin |
T8 | 277-284 | GeneOrGeneProduct | denotes | induced |
T9 | 348-356 | GeneOrGeneProduct | denotes | gankyrin |
T10 | 445-453 | GeneOrGeneProduct | denotes | gankyrin |
T11 | 484-488 | GeneOrGeneProduct | denotes | mice |
T12 | 494-499 | GeneOrGeneProduct | denotes | liver |
T13 | 512-516 | GeneOrGeneProduct | denotes | cell |
T14 | 526-534 | GeneOrGeneProduct | denotes | gankyrin |
T15 | 545-552 | GeneOrGeneProduct | denotes | Alb-Cre |
T16 | 553-561 | GeneOrGeneProduct | denotes | gankyrin |
T17 | 573-581 | GeneOrGeneProduct | denotes | gankyrin |
T18 | 599-604 | GeneOrGeneProduct | denotes | liver |
T19 | 637-642 | GeneOrGeneProduct | denotes | cells |
T20 | 644-647 | GeneOrGeneProduct | denotes | Mx1 |
T21 | 652-660 | GeneOrGeneProduct | denotes | gankyrin |
T22 | 669-677 | GeneOrGeneProduct | denotes | Gankyrin |
T23 | 690-694 | GeneOrGeneProduct | denotes | VEGF |
T24 | 709-714 | GeneOrGeneProduct | denotes | tumor |
T25 | 715-720 | GeneOrGeneProduct | denotes | cells |
T26 | 722-730 | GeneOrGeneProduct | denotes | Gankyrin |
T27 | 731-736 | GeneOrGeneProduct | denotes | binds |
T28 | 744-752 | GeneOrGeneProduct | denotes | homology |
T29 | 755-780 | GeneOrGeneProduct | denotes | domain-containing protein |
T30 | 781-801 | GeneOrGeneProduct | denotes | tyrosine phosphatase |
T31 | 805-810 | GeneOrGeneProduct | denotes | SHP-1 |
T32 | 813-819 | GeneOrGeneProduct | denotes | mainly |
T33 | 833-838 | GeneOrGeneProduct | denotes | liver |
T34 | 855-860 | GeneOrGeneProduct | denotes | cells |
T35 | 895-905 | GeneOrGeneProduct | denotes | activation |
T36 | 909-957 | GeneOrGeneProduct | denotes | signal transducer and activator of transcription |
T37 | 961-966 | GeneOrGeneProduct | denotes | STAT3 |
T38 | 969-977 | GeneOrGeneProduct | denotes | Gankyrin |
T39 | 1008-1013 | GeneOrGeneProduct | denotes | cells |
T40 | 1038-1043 | GeneOrGeneProduct | denotes | cells |
T41 | 1045-1052 | GeneOrGeneProduct | denotes | reduced |
T42 | 1053-1058 | GeneOrGeneProduct | denotes | STAT3 |
T43 | 1059-1067 | GeneOrGeneProduct | denotes | activity |
T44 | 1081-1087 | GeneOrGeneProduct | denotes | (IL)-6 |
T45 | 1088-1098 | GeneOrGeneProduct | denotes | production |
T46 | 1116-1120 | GeneOrGeneProduct | denotes | cell |
T47 | 1129-1133 | GeneOrGeneProduct | denotes | Bmi1 |
T48 | 1138-1171 | GeneOrGeneProduct | denotes | epithelial cell adhesion molecule |
T49 | 1173-1178 | GeneOrGeneProduct | denotes | EpCAM |
T50 | 1204-1214 | GeneOrGeneProduct | denotes | attenuated |
T51 | 1269-1277 | GeneOrGeneProduct | denotes | gankyrin |
T52 | 1302-1307 | GeneOrGeneProduct | denotes | liver |
T53 | 1309-1317 | GeneOrGeneProduct | denotes | Gankyrin |
T54 | 1474-1482 | GeneOrGeneProduct | denotes | gankyrin |
T55 | 1510-1519 | GeneOrGeneProduct | denotes | oncogenic |
T56 | 1560-1568 | GeneOrGeneProduct | denotes | may be a |
T57 | 1692-1695 | GeneOrGeneProduct | denotes | All |
T58 | 1696-1702 | GeneOrGeneProduct | denotes | rights |
LitCoin-GeneOrGeneProduct-v2
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 0-8 | GeneOrGeneProduct | denotes | Gankyrin |
T2 | 17-22 | GeneOrGeneProduct | denotes | STAT3 |
T3 | 184-189 | GeneOrGeneProduct | denotes | liver |
T4 | 239-247 | GeneOrGeneProduct | denotes | gankyrin |
T5 | 348-356 | GeneOrGeneProduct | denotes | gankyrin |
T6 | 445-453 | GeneOrGeneProduct | denotes | gankyrin |
T7 | 494-499 | GeneOrGeneProduct | denotes | liver |
T8 | 512-516 | GeneOrGeneProduct | denotes | cell |
T9 | 526-534 | GeneOrGeneProduct | denotes | gankyrin |
T10 | 545-552 | GeneOrGeneProduct | denotes | Alb-Cre |
T11 | 553-561 | GeneOrGeneProduct | denotes | gankyrin |
T12 | 573-581 | GeneOrGeneProduct | denotes | gankyrin |
T13 | 599-604 | GeneOrGeneProduct | denotes | liver |
T14 | 644-647 | GeneOrGeneProduct | denotes | Mx1 |
T15 | 652-660 | GeneOrGeneProduct | denotes | gankyrin |
T16 | 669-677 | GeneOrGeneProduct | denotes | Gankyrin |
T17 | 690-694 | GeneOrGeneProduct | denotes | VEGF |
T18 | 722-730 | GeneOrGeneProduct | denotes | Gankyrin |
T19 | 755-780 | GeneOrGeneProduct | denotes | domain-containing protein |
T20 | 781-801 | GeneOrGeneProduct | denotes | tyrosine phosphatase |
T21 | 805-810 | GeneOrGeneProduct | denotes | SHP-1 |
T22 | 833-838 | GeneOrGeneProduct | denotes | liver |
T23 | 909-957 | GeneOrGeneProduct | denotes | signal transducer and activator of transcription |
T24 | 961-966 | GeneOrGeneProduct | denotes | STAT3 |
T25 | 969-977 | GeneOrGeneProduct | denotes | Gankyrin |
T26 | 1045-1052 | GeneOrGeneProduct | denotes | reduced |
T27 | 1053-1058 | GeneOrGeneProduct | denotes | STAT3 |
T28 | 1116-1120 | GeneOrGeneProduct | denotes | cell |
T29 | 1129-1133 | GeneOrGeneProduct | denotes | Bmi1 |
T30 | 1138-1171 | GeneOrGeneProduct | denotes | epithelial cell adhesion molecule |
T31 | 1173-1178 | GeneOrGeneProduct | denotes | EpCAM |
T32 | 1204-1214 | GeneOrGeneProduct | denotes | attenuated |
T33 | 1269-1277 | GeneOrGeneProduct | denotes | gankyrin |
T34 | 1302-1307 | GeneOrGeneProduct | denotes | liver |
T35 | 1309-1317 | GeneOrGeneProduct | denotes | Gankyrin |
T36 | 1474-1482 | GeneOrGeneProduct | denotes | gankyrin |
LitCoin-Disease-MeSH
Id | Subject | Object | Predicate | Lexical cue | originalLabel |
---|---|---|---|---|---|
T1 | 37-43 | DiseaseOrPhenotypicFeature | denotes | tumour | DISEASE |
T2 | 89-113 | DiseaseOrPhenotypicFeature | denotes | hepatocellular carcinoma | D006528 |
T3 | 120-145 | DiseaseOrPhenotypicFeature | denotes | hepatocellular carcinomas | D006528 |
T4 | 147-151 | DiseaseOrPhenotypicFeature | denotes | HCCs | D006528 |
T5 | 190-202 | DiseaseOrPhenotypicFeature | denotes | inflammation | D007249 |
T6 | 264-276 | DiseaseOrPhenotypicFeature | denotes | inflammation | D007249 |
T7 | 457-463 | DiseaseOrPhenotypicFeature | denotes | tumour | DISEASE |
T8 | 709-714 | DiseaseOrPhenotypicFeature | denotes | tumor | D009369 |
T9 | 1104-1110 | DiseaseOrPhenotypicFeature | denotes | cancer | D009369 |
T10 | 1247-1259 | DiseaseOrPhenotypicFeature | denotes | inflammation | D007249 |
T11 | 1336-1342 | DiseaseOrPhenotypicFeature | denotes | tumour | DISEASE |
T12 | 1463-1466 | DiseaseOrPhenotypicFeature | denotes | HCC | DISEASE |
T13 | 1532-1538 | DiseaseOrPhenotypicFeature | denotes | tumour | DISEASE |
T14 | 1647-1650 | DiseaseOrPhenotypicFeature | denotes | HCC | DISEASE |
LitCoin-GeneOrGeneProduct-v3
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 0-8 | GeneOrGeneProduct | denotes | Gankyrin |
T2 | 17-22 | GeneOrGeneProduct | denotes | STAT3 |
T3 | 239-247 | GeneOrGeneProduct | denotes | gankyrin |
T4 | 348-356 | GeneOrGeneProduct | denotes | gankyrin |
T5 | 445-453 | GeneOrGeneProduct | denotes | gankyrin |
T6 | 526-534 | GeneOrGeneProduct | denotes | gankyrin |
T7 | 545-552 | GeneOrGeneProduct | denotes | Alb-Cre |
T8 | 553-561 | GeneOrGeneProduct | denotes | gankyrin |
T9 | 573-581 | GeneOrGeneProduct | denotes | gankyrin |
T10 | 644-647 | GeneOrGeneProduct | denotes | Mx1 |
T11 | 652-660 | GeneOrGeneProduct | denotes | gankyrin |
T12 | 669-677 | GeneOrGeneProduct | denotes | Gankyrin |
T13 | 690-694 | GeneOrGeneProduct | denotes | VEGF |
T14 | 722-730 | GeneOrGeneProduct | denotes | Gankyrin |
T15 | 755-780 | GeneOrGeneProduct | denotes | domain-containing protein |
T16 | 781-801 | GeneOrGeneProduct | denotes | tyrosine phosphatase |
T17 | 805-810 | GeneOrGeneProduct | denotes | SHP-1 |
T18 | 909-957 | GeneOrGeneProduct | denotes | signal transducer and activator of transcription |
T19 | 961-966 | GeneOrGeneProduct | denotes | STAT3 |
T20 | 969-977 | GeneOrGeneProduct | denotes | Gankyrin |
T21 | 1053-1058 | GeneOrGeneProduct | denotes | STAT3 |
T22 | 1129-1133 | GeneOrGeneProduct | denotes | Bmi1 |
T23 | 1138-1171 | GeneOrGeneProduct | denotes | epithelial cell adhesion molecule |
T24 | 1173-1178 | GeneOrGeneProduct | denotes | EpCAM |
T25 | 1269-1277 | GeneOrGeneProduct | denotes | gankyrin |
T26 | 1309-1317 | GeneOrGeneProduct | denotes | Gankyrin |
T27 | 1474-1482 | GeneOrGeneProduct | denotes | gankyrin |
LitCoin_Mondo_095
Id | Subject | Object | Predicate | Lexical cue | mondo_id |
---|---|---|---|---|---|
T1 | 89-113 | DiseaseOrPhenotypicFeature | denotes | hepatocellular carcinoma | 0007256 |
T2 | 120-145 | DiseaseOrPhenotypicFeature | denotes | hepatocellular carcinomas | 0007256 |
T3 | 147-151 | DiseaseOrPhenotypicFeature | denotes | HCCs | 0007256 |
T4 | 184-202 | DiseaseOrPhenotypicFeature | denotes | liver inflammation | 0002251 |
T5 | 709-714 | DiseaseOrPhenotypicFeature | denotes | tumor | 0005070 |
T6 | 1463-1466 | DiseaseOrPhenotypicFeature | denotes | HCC | 0007256 |
T7 | 1647-1650 | DiseaseOrPhenotypicFeature | denotes | HCC | 0007256 |
LitCoin-MeSH-Disease-2
Id | Subject | Object | Predicate | Lexical cue | ID: |
---|---|---|---|---|---|
T1 | 37-43 | DiseaseOrPhenotypicFeature | denotes | tumour | DISEASE |
T2 | 89-113 | DiseaseOrPhenotypicFeature | denotes | hepatocellular carcinoma | D006528 |
T3 | 120-145 | DiseaseOrPhenotypicFeature | denotes | hepatocellular carcinomas | D006528 |
T4 | 147-151 | DiseaseOrPhenotypicFeature | denotes | HCCs | D006528 |
T5 | 190-202 | DiseaseOrPhenotypicFeature | denotes | inflammation | DISEASE|D007249 |
T7 | 264-276 | DiseaseOrPhenotypicFeature | denotes | inflammation | DISEASE|D007249 |
T9 | 285-299 | DiseaseOrPhenotypicFeature | denotes | tumourigenesis | DISEASE |
T10 | 457-463 | DiseaseOrPhenotypicFeature | denotes | tumour | DISEASE |
T11 | 709-714 | DiseaseOrPhenotypicFeature | denotes | tumor | D009369 |
T12 | 1104-1110 | DiseaseOrPhenotypicFeature | denotes | cancer | D009369 |
T13 | 1215-1227 | DiseaseOrPhenotypicFeature | denotes | tumourigenic | DISEASE |
T14 | 1247-1259 | DiseaseOrPhenotypicFeature | denotes | inflammation | DISEASE|D007249 |
T16 | 1336-1342 | DiseaseOrPhenotypicFeature | denotes | tumour | DISEASE |
T17 | 1463-1466 | DiseaseOrPhenotypicFeature | denotes | HCC | DISEASE |
T18 | 1532-1538 | DiseaseOrPhenotypicFeature | denotes | tumour | DISEASE |
T19 | 1647-1650 | DiseaseOrPhenotypicFeature | denotes | HCC | DISEASE |
LitCoin-MONDO_bioort2019
Id | Subject | Object | Predicate | Lexical cue | #label |
---|---|---|---|---|---|
T1 | 37-43 | DiseaseOrPhenotypicFeature | denotes | tumour | DISEASE |
T2 | 89-113 | DiseaseOrPhenotypicFeature | denotes | hepatocellular carcinoma | D006528 |
T3 | 120-145 | DiseaseOrPhenotypicFeature | denotes | hepatocellular carcinomas | D006528 |
T4 | 147-151 | DiseaseOrPhenotypicFeature | denotes | HCCs | D006528 |
T5 | 190-202 | DiseaseOrPhenotypicFeature | denotes | inflammation | D007249 |
T6 | 264-276 | DiseaseOrPhenotypicFeature | denotes | inflammation | D007249 |
T7 | 285-299 | DiseaseOrPhenotypicFeature | denotes | tumourigenesis | DISEASE |
T8 | 457-463 | DiseaseOrPhenotypicFeature | denotes | tumour | DISEASE |
T9 | 709-714 | DiseaseOrPhenotypicFeature | denotes | tumor | D009369 |
T10 | 1104-1110 | DiseaseOrPhenotypicFeature | denotes | cancer | D009369 |
T11 | 1215-1227 | DiseaseOrPhenotypicFeature | denotes | tumourigenic | DISEASE |
T12 | 1247-1259 | DiseaseOrPhenotypicFeature | denotes | inflammation | D007249 |
T13 | 1336-1342 | DiseaseOrPhenotypicFeature | denotes | tumour | DISEASE |
T14 | 1463-1466 | DiseaseOrPhenotypicFeature | denotes | HCC | DISEASE |
T15 | 1532-1538 | DiseaseOrPhenotypicFeature | denotes | tumour | DISEASE |
T16 | 1647-1650 | DiseaseOrPhenotypicFeature | denotes | HCC | DISEASE |
LitCoin-NCBITaxon-2
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 484-488 | OrganismTaxon | denotes | mice |
T2 | 1296-1301 | OrganismTaxon | denotes | human |
T3 | 1419-1427 | OrganismTaxon | denotes | patients |
LitCoin-Chemical-MeSH-CHEBI
Id | Subject | Object | Predicate | Lexical cue | ID: |
---|---|---|---|---|---|
T1 | 65-74 | ChemicalEntity | denotes | sorafenib | D000077157|http://purl.obolibrary.org/obo/CHEBI_50924 |
T3 | 781-789 | ChemicalEntity | denotes | tyrosine | http://purl.obolibrary.org/obo/CHEBI_18186 |
T4 | 790-801 | ChemicalEntity | denotes | phosphatase | D010744 |
T5 | 1439-1448 | ChemicalEntity | denotes | sorafenib | D000077157|http://purl.obolibrary.org/obo/CHEBI_50924 |
LitCoin-training-merged
Id | Subject | Object | Predicate | Lexical cue | #label | ID: |
---|---|---|---|---|---|---|
T5 | 1439-1448 | ChemicalEntity | denotes | sorafenib | http://purl.obolibrary.org/obo/CHEBI_50924|D000077157 | |
T4 | 790-801 | ChemicalEntity | denotes | phosphatase | D010744 | |
T3 | 781-789 | ChemicalEntity | denotes | tyrosine | http://purl.obolibrary.org/obo/CHEBI_18186 | |
T1 | 65-74 | ChemicalEntity | denotes | sorafenib | http://purl.obolibrary.org/obo/CHEBI_50924|D000077157 | |
T27 | 1474-1482 | GeneOrGeneProduct | denotes | gankyrin | ||
T26 | 1309-1317 | GeneOrGeneProduct | denotes | Gankyrin | ||
T25 | 1269-1277 | GeneOrGeneProduct | denotes | gankyrin | ||
T24 | 1173-1178 | GeneOrGeneProduct | denotes | EpCAM | ||
T23 | 1138-1171 | GeneOrGeneProduct | denotes | epithelial cell adhesion molecule | ||
T22 | 1129-1133 | GeneOrGeneProduct | denotes | Bmi1 | ||
T21 | 1053-1058 | GeneOrGeneProduct | denotes | STAT3 | ||
T20 | 969-977 | GeneOrGeneProduct | denotes | Gankyrin | ||
T19 | 961-966 | GeneOrGeneProduct | denotes | STAT3 | ||
T18 | 909-957 | GeneOrGeneProduct | denotes | signal transducer and activator of transcription | ||
T17 | 805-810 | GeneOrGeneProduct | denotes | SHP-1 | ||
T16 | 781-801 | GeneOrGeneProduct | denotes | tyrosine phosphatase | ||
T15 | 755-780 | GeneOrGeneProduct | denotes | domain-containing protein | ||
T14 | 722-730 | GeneOrGeneProduct | denotes | Gankyrin | ||
T13 | 690-694 | GeneOrGeneProduct | denotes | VEGF | ||
T12 | 669-677 | GeneOrGeneProduct | denotes | Gankyrin | ||
T11 | 652-660 | GeneOrGeneProduct | denotes | gankyrin | ||
T10 | 644-647 | GeneOrGeneProduct | denotes | Mx1 | ||
T9 | 573-581 | GeneOrGeneProduct | denotes | gankyrin | ||
T8 | 553-561 | GeneOrGeneProduct | denotes | gankyrin | ||
T7 | 545-552 | GeneOrGeneProduct | denotes | Alb-Cre | ||
T6 | 526-534 | GeneOrGeneProduct | denotes | gankyrin | ||
T72501 | 445-453 | GeneOrGeneProduct | denotes | gankyrin | ||
T15851 | 348-356 | GeneOrGeneProduct | denotes | gankyrin | ||
T89212 | 239-247 | GeneOrGeneProduct | denotes | gankyrin | ||
T2 | 17-22 | GeneOrGeneProduct | denotes | STAT3 | ||
T74841 | 0-8 | GeneOrGeneProduct | denotes | Gankyrin | ||
T98522 | 1647-1650 | DiseaseOrPhenotypicFeature | denotes | HCC | DISEASE | |
T88120 | 1532-1538 | DiseaseOrPhenotypicFeature | denotes | tumour | DISEASE | |
T92949 | 1463-1466 | DiseaseOrPhenotypicFeature | denotes | HCC | DISEASE | |
T90271 | 1336-1342 | DiseaseOrPhenotypicFeature | denotes | tumour | DISEASE | |
T20570 | 1247-1259 | DiseaseOrPhenotypicFeature | denotes | inflammation | D007249 | |
T69949 | 1215-1227 | DiseaseOrPhenotypicFeature | denotes | tumourigenic | DISEASE | |
T22785 | 1104-1110 | DiseaseOrPhenotypicFeature | denotes | cancer | D009369 | |
T19203 | 709-714 | DiseaseOrPhenotypicFeature | denotes | tumor | D009369 | |
T69700 | 457-463 | DiseaseOrPhenotypicFeature | denotes | tumour | DISEASE | |
T1253 | 285-299 | DiseaseOrPhenotypicFeature | denotes | tumourigenesis | DISEASE | |
T32815 | 264-276 | DiseaseOrPhenotypicFeature | denotes | inflammation | D007249 | |
T48597 | 190-202 | DiseaseOrPhenotypicFeature | denotes | inflammation | D007249 | |
T51567 | 147-151 | DiseaseOrPhenotypicFeature | denotes | HCCs | D006528 | |
T99019 | 120-145 | DiseaseOrPhenotypicFeature | denotes | hepatocellular carcinomas | D006528 | |
T69082 | 89-113 | DiseaseOrPhenotypicFeature | denotes | hepatocellular carcinoma | D006528 | |
T24854 | 37-43 | DiseaseOrPhenotypicFeature | denotes | tumour | DISEASE | |
T69835 | 1419-1427 | OrganismTaxon | denotes | patients | ||
T88377 | 1296-1301 | OrganismTaxon | denotes | human | ||
T65791 | 484-488 | OrganismTaxon | denotes | mice |