PubMed:28747658 / 0-514 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PubMed/sourceid/28747658","sourcedb":"PubMed","sourceid":"28747658","text":"A single amino acid substitution confers B-cell clonogenic activity to the HIV-1 matrix protein p17.\nRecent data highlight the presence, in HIV-1-seropositive patients with lymphoma, of p17 variants (vp17s) endowed with B-cell clonogenicity, suggesting a role of vp17s in lymphomagenesis. We investigated the mechanisms responsible for the functional disparity on B cells between a wild-type p17 (refp17) and a vp17 named S75X. Here, we show that a single Arginine (R) to Glycine (G) mutation at position 76 in 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