PubMed:28727069
Annnotations
{"target":"https://pubannotation.org/docs/sourcedb/PubMed/sourceid/28727069","sourcedb":"PubMed","sourceid":"28727069","text":"System dynamics modeling in designing breeding schemes: The case of Menz sheep in Ethiopian highlands.\nA comprehensive dynamic simulation model was developed to describe a community-based breeding program for the Menz sheep population of Ethiopia. Selection of male and female animals based on their own and maternal performance was simulated. The breeding goal traits were 6-mo weight, preweaning survival, and fertility rate. The model input data were obtained from the flock book, questionnaires, and references. The simulation model used a mix of deterministic and stochastic procedures to model the complex system. In the baseline scenario, the proportion of selected male and female animals varied between 20 and 30% and between 70 and 80%, respectively. A reasonable annual genetic gain was predicted for the breeding goal traits at the village level. For 6-mo weight and preweaning survival rate, the annual genetic gain varied from 0.213 to 0.214 kg and 0.255 to 0.256%, respectively. For fertility rate, an annual genetic gain of 0.063% was obtained. The predicted rate of inbreeding per year was between 0.094 and 0.116%. Furthermore, a scenario analysis was conducted by varying the proportions of selected animals. Annual genetic gains of 0.230 kg, 0.277%, and 0.069% were obtained for 6-mo weight, preweaning survival rate, and fertility rate, respectively, when the proportion of selected male and female animals decreased by 10%. The annual genetic gains decreased to 0.198 kg, 0.236%, and 0.059%, respectively, when the selection proportion of male and female animals increased by 10%. The lowest rate of inbreeding per year, ranging from 0.065 to 0.079%, was achieved when the selection proportion of selected male and female animals increased. The model is relevant for the step-by-step evaluation of more than one round of selection. It is flexible and usage driven. The model is a valuable tool to design different population structures and can be easily expanded to adopt different breeding strategies. Hence, the system dynamics modeling approach is a potential tool to describe complex breeding programs.","tracks":[{"project":"PubMed_ArguminSci","denotations":[{"id":"T1","span":{"begin":103,"end":247},"obj":"DRI_Challenge"},{"id":"T2","span":{"begin":248,"end":343},"obj":"DRI_Background"},{"id":"T3","span":{"begin":344,"end":427},"obj":"DRI_Background"},{"id":"T4","span":{"begin":428,"end":515},"obj":"DRI_Approach"},{"id":"T5","span":{"begin":516,"end":619},"obj":"DRI_Background"},{"id":"T6","span":{"begin":620,"end":760},"obj":"DRI_Outcome"},{"id":"T7","span":{"begin":761,"end":858},"obj":"DRI_Outcome"},{"id":"T8","span":{"begin":859,"end":993},"obj":"DRI_Background"},{"id":"T9","span":{"begin":994,"end":1060},"obj":"DRI_Background"},{"id":"T10","span":{"begin":1061,"end":1132},"obj":"DRI_Outcome"},{"id":"T11","span":{"begin":1133,"end":1227},"obj":"DRI_Background"},{"id":"T12","span":{"begin":1228,"end":1445},"obj":"DRI_Background"},{"id":"T13","span":{"begin":1446,"end":1602},"obj":"DRI_Outcome"},{"id":"T14","span":{"begin":1603,"end":1762},"obj":"DRI_Outcome"},{"id":"T15","span":{"begin":1763,"end":1853},"obj":"DRI_Outcome"},{"id":"T16","span":{"begin":1854,"end":1886},"obj":"DRI_Approach"},{"id":"T17","span":{"begin":1887,"end":2024},"obj":"DRI_Challenge"},{"id":"T18","span":{"begin":2025,"end":2128},"obj":"DRI_Challenge"}],"attributes":[{"subj":"T1","pred":"source","obj":"PubMed_ArguminSci"},{"subj":"T2","pred":"source","obj":"PubMed_ArguminSci"},{"subj":"T3","pred":"source","obj":"PubMed_ArguminSci"},{"subj":"T4","pred":"source","obj":"PubMed_ArguminSci"},{"subj":"T5","pred":"source","obj":"PubMed_ArguminSci"},{"subj":"T6","pred":"source","obj":"PubMed_ArguminSci"},{"subj":"T7","pred":"source","obj":"PubMed_ArguminSci"},{"subj":"T8","pred":"source","obj":"PubMed_ArguminSci"},{"subj":"T9","pred":"source","obj":"PubMed_ArguminSci"},{"subj":"T10","pred":"source","obj":"PubMed_ArguminSci"},{"subj":"T11","pred":"source","obj":"PubMed_ArguminSci"},{"subj":"T12","pred":"source","obj":"PubMed_ArguminSci"},{"subj":"T13","pred":"source","obj":"PubMed_ArguminSci"},{"subj":"T14","pred":"source","obj":"PubMed_ArguminSci"},{"subj":"T15","pred":"source","obj":"PubMed_ArguminSci"},{"subj":"T16","pred":"source","obj":"PubMed_ArguminSci"},{"subj":"T17","pred":"source","obj":"PubMed_ArguminSci"},{"subj":"T18","pred":"source","obj":"PubMed_ArguminSci"}]},{"project":"GoldHamster","denotations":[{"id":"T1","span":{"begin":73,"end":78},"obj":"9940"},{"id":"T2","span":{"begin":73,"end":78},"obj":"D012756"},{"id":"T3","span":{"begin":218,"end":223},"obj":"9940"},{"id":"T4","span":{"begin":218,"end":223},"obj":"D012756"},{"id":"T5","span":{"begin":261,"end":265},"obj":"UBERON:0003101"},{"id":"T6","span":{"begin":261,"end":265},"obj":"CHEBI:30780"},{"id":"T7","span":{"begin":270,"end":276},"obj":"UBERON:0003100"},{"id":"T8","span":{"begin":362,"end":368},"obj":"PR:Q96CJ1"},{"id":"T9","span":{"begin":362,"end":368},"obj":"PR:000006862"},{"id":"T10","span":{"begin":362,"end":368},"obj":"PR:Q91ZD6"},{"id":"T11","span":{"begin":362,"end":368},"obj":"PR:Q811X5"},{"id":"T12","span":{"begin":673,"end":677},"obj":"UBERON:0003101"},{"id":"T13","span":{"begin":673,"end":677},"obj":"CHEBI:30780"},{"id":"T14","span":{"begin":682,"end":688},"obj":"UBERON:0003100"},{"id":"T15","span":{"begin":789,"end":793},"obj":"SO:0001742"},{"id":"T16","span":{"begin":798,"end":807},"obj":"SO:0000732"},{"id":"T17","span":{"begin":830,"end":836},"obj":"PR:Q96CJ1"},{"id":"T18","span":{"begin":830,"end":836},"obj":"PR:000006862"},{"id":"T19","span":{"begin":830,"end":836},"obj":"PR:Q91ZD6"},{"id":"T20","span":{"begin":830,"end":836},"obj":"PR:Q811X5"},{"id":"T21","span":{"begin":924,"end":928},"obj":"SO:0001742"},{"id":"T22","span":{"begin":1032,"end":1036},"obj":"SO:0001742"},{"id":"T23","span":{"begin":1065,"end":1074},"obj":"SO:0000732"},{"id":"T24","span":{"begin":1404,"end":1408},"obj":"UBERON:0003101"},{"id":"T25","span":{"begin":1404,"end":1408},"obj":"CHEBI:30780"},{"id":"T26","span":{"begin":1413,"end":1419},"obj":"UBERON:0003100"},{"id":"T27","span":{"begin":1561,"end":1565},"obj":"UBERON:0003101"},{"id":"T28","span":{"begin":1561,"end":1565},"obj":"CHEBI:30780"},{"id":"T29","span":{"begin":1570,"end":1576},"obj":"UBERON:0003100"},{"id":"T30","span":{"begin":1728,"end":1732},"obj":"UBERON:0003101"},{"id":"T31","span":{"begin":1728,"end":1732},"obj":"CHEBI:30780"},{"id":"T32","span":{"begin":1737,"end":1743},"obj":"UBERON:0003100"}],"attributes":[{"subj":"T1","pred":"source","obj":"GoldHamster"},{"subj":"T2","pred":"source","obj":"GoldHamster"},{"subj":"T3","pred":"source","obj":"GoldHamster"},{"subj":"T4","pred":"source","obj":"GoldHamster"},{"subj":"T5","pred":"source","obj":"GoldHamster"},{"subj":"T6","pred":"source","obj":"GoldHamster"},{"subj":"T7","pred":"source","obj":"GoldHamster"},{"subj":"T8","pred":"source","obj":"GoldHamster"},{"subj":"T9","pred":"source","obj":"GoldHamster"},{"subj":"T10","pred":"source","obj":"GoldHamster"},{"subj":"T11","pred":"source","obj":"GoldHamster"},{"subj":"T12","pred":"source","obj":"GoldHamster"},{"subj":"T13","pred":"source","obj":"GoldHamster"},{"subj":"T14","pred":"source","obj":"GoldHamster"},{"subj":"T15","pred":"source","obj":"GoldHamster"},{"subj":"T16","pred":"source","obj":"GoldHamster"},{"subj":"T17","pred":"source","obj":"GoldHamster"},{"subj":"T18","pred":"source","obj":"GoldHamster"},{"subj":"T19","pred":"source","obj":"GoldHamster"},{"subj":"T20","pred":"source","obj":"GoldHamster"},{"subj":"T21","pred":"source","obj":"GoldHamster"},{"subj":"T22","pred":"source","obj":"GoldHamster"},{"subj":"T23","pred":"source","obj":"GoldHamster"},{"subj":"T24","pred":"source","obj":"GoldHamster"},{"subj":"T25","pred":"source","obj":"GoldHamster"},{"subj":"T26","pred":"source","obj":"GoldHamster"},{"subj":"T27","pred":"source","obj":"GoldHamster"},{"subj":"T28","pred":"source","obj":"GoldHamster"},{"subj":"T29","pred":"source","obj":"GoldHamster"},{"subj":"T30","pred":"source","obj":"GoldHamster"},{"subj":"T31","pred":"source","obj":"GoldHamster"},{"subj":"T32","pred":"source","obj":"GoldHamster"}]},{"project":"Goldhamster2_Cellosaurus","denotations":[{"id":"T1","span":{"begin":103,"end":104},"obj":"CVCL_6479|Finite_cell_line|Mus musculus"},{"id":"T2","span":{"begin":170,"end":171},"obj":"CVCL_6479|Finite_cell_line|Mus musculus"},{"id":"T3","span":{"begin":376,"end":378},"obj":"CVCL_1439|Cancer_cell_line|Homo sapiens"},{"id":"T4","span":{"begin":376,"end":378},"obj":"CVCL_7019|Cancer_cell_line|Homo sapiens"},{"id":"T5","span":{"begin":542,"end":543},"obj":"CVCL_6479|Finite_cell_line|Mus musculus"},{"id":"T6","span":{"begin":712,"end":714},"obj":"CVCL_J923|Hybridoma|Mus musculus"},{"id":"T7","span":{"begin":719,"end":721},"obj":"CVCL_J925|Hybridoma|Mus musculus"},{"id":"T8","span":{"begin":761,"end":762},"obj":"CVCL_6479|Finite_cell_line|Mus musculus"},{"id":"T9","span":{"begin":865,"end":867},"obj":"CVCL_1439|Cancer_cell_line|Homo sapiens"},{"id":"T10","span":{"begin":865,"end":867},"obj":"CVCL_7019|Cancer_cell_line|Homo sapiens"},{"id":"T11","span":{"begin":1014,"end":1016},"obj":"CVCL_8754|Cancer_cell_line|Homo sapiens"},{"id":"T12","span":{"begin":1014,"end":1016},"obj":"CVCL_H241|Cancer_cell_line|Homo sapiens"},{"id":"T13","span":{"begin":1146,"end":1147},"obj":"CVCL_6479|Finite_cell_line|Mus musculus"},{"id":"T14","span":{"begin":1301,"end":1303},"obj":"CVCL_1439|Cancer_cell_line|Homo sapiens"},{"id":"T15","span":{"begin":1301,"end":1303},"obj":"CVCL_7019|Cancer_cell_line|Homo sapiens"},{"id":"T16","span":{"begin":1830,"end":1833},"obj":"CVCL_Z424|Spontaneously_immortalized_cell_line|Ostrinia nubilalis"},{"id":"T17","span":{"begin":1900,"end":1901},"obj":"CVCL_6479|Finite_cell_line|Mus musculus"},{"id":"T18","span":{"begin":2073,"end":2074},"obj":"CVCL_6479|Finite_cell_line|Mus musculus"}],"attributes":[{"subj":"T1","pred":"source","obj":"Goldhamster2_Cellosaurus"},{"subj":"T2","pred":"source","obj":"Goldhamster2_Cellosaurus"},{"subj":"T3","pred":"source","obj":"Goldhamster2_Cellosaurus"},{"subj":"T4","pred":"source","obj":"Goldhamster2_Cellosaurus"},{"subj":"T5","pred":"source","obj":"Goldhamster2_Cellosaurus"},{"subj":"T6","pred":"source","obj":"Goldhamster2_Cellosaurus"},{"subj":"T7","pred":"source","obj":"Goldhamster2_Cellosaurus"},{"subj":"T8","pred":"source","obj":"Goldhamster2_Cellosaurus"},{"subj":"T9","pred":"source","obj":"Goldhamster2_Cellosaurus"},{"subj":"T10","pred":"source","obj":"Goldhamster2_Cellosaurus"},{"subj":"T11","pred":"source","obj":"Goldhamster2_Cellosaurus"},{"subj":"T12","pred":"source","obj":"Goldhamster2_Cellosaurus"},{"subj":"T13","pred":"source","obj":"Goldhamster2_Cellosaurus"},{"subj":"T14","pred":"source","obj":"Goldhamster2_Cellosaurus"},{"subj":"T15","pred":"source","obj":"Goldhamster2_Cellosaurus"},{"subj":"T16","pred":"source","obj":"Goldhamster2_Cellosaurus"},{"subj":"T17","pred":"source","obj":"Goldhamster2_Cellosaurus"},{"subj":"T18","pred":"source","obj":"Goldhamster2_Cellosaurus"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"PubMed_ArguminSci","color":"#ec93ab","default":true},{"id":"GoldHamster","color":"#93c5ec"},{"id":"Goldhamster2_Cellosaurus","color":"#dfec93"}]}]}}