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PubMed_ArguminSci

Id Subject Object Predicate Lexical cue
T1 138-280 DRI_Background denotes The objective of this study was to assess the differentiation capability of synoviocytes derived from dogs with inflammatory joint conditions.
T2 281-442 DRI_Background denotes Cranial cruciate ligament ruptured (CCLr) (n=12) and medial patella luxated (MPL) (n=10) knee joints of the dogs were used to collect the synovial membrane (SM).
T3 443-667 DRI_Approach denotes Synoviocytes were enzymatically released from the SM and analyzed by flow cytometry for specific cellular markers (CD44 and CD90) of mesenchymal stem cells (MSCs), while doing histopathology from another part of SM sections.
T4 668-848 DRI_Background denotes Under specific culture conditions, synoviocytes were forced to differentiate into chondrogenesis, adipogenesis, osteogenesis and osteoclastogenesis to investigate the multipotency.
T5 849-1054 DRI_Background denotes Upon treatments phenotypes of cell cultures were analyzed by histopathology and by semi-quantitative reverse transcriptase polymerase chain reaction for the expression of each differentiation marker genes.
T6 1055-1230 DRI_Background denotes Although flow cytometry showing similar MSCs populations in CCLr and MPL synovium, synovial cells derived from CCLr showed higher multipotency compared to MPL-derived samples.
T7 1231-1398 DRI_Background denotes Further, synovial changes such as vascularity, mononuclear cell infiltration and cellular hypertrophy were more pronounced in CCLr-derived synovial tissue than in MPL.
T8 1399-1587 DRI_Background denotes Taken together, these findings suggested that the differentiation capability of SM-derived multipotent stem cells varies with inflammatory severity occurring in different joint conditions.

Goldhamster2_Cellosaurus

Id Subject Object Predicate Lexical cue
T1 438-440 CVCL_7004|Cancer_cell_line|Homo sapiens denotes SM
T2 493-495 CVCL_7004|Cancer_cell_line|Homo sapiens denotes SM
T3 655-657 CVCL_7004|Cancer_cell_line|Homo sapiens denotes SM
T4 1249-1256 CVCL_0238|Cancer_cell_line|Homo sapiens denotes changes
T5 1479-1481 CVCL_7004|Cancer_cell_line|Homo sapiens denotes SM

GoldHamster

Id Subject Object Predicate Lexical cue
T1 55-61 UBERON:0000982 denotes joints
T2 75-92 UBERON:0006659 denotes cruciate ligament
T5 93-100 D012421 denotes rupture
T6 93-100 D012421 denotes rupture
T7 112-119 UBERON:0002446 denotes patella
T8 132-136 D004285 denotes dogs
T9 240-244 D004285 denotes dogs
T10 263-268 UBERON:0004905 denotes joint
T11 263-268 UBERON:0000982 denotes joint
T12 289-306 UBERON:0006659 denotes cruciate ligament
T17 341-348 UBERON:0002446 denotes patella
T18 358-361 PR:P40238 denotes MPL
T20 358-361 PR:000023277 denotes MPL
T21 358-361 PR:000001939 denotes MPL
T22 358-361 PR:Q08351 denotes MPL
T23 358-361 PR:P37773 denotes MPL
T19 358-361 UBERON:0002662 denotes MPL
T26 370-374 UBERON:0009005 denotes knee
T27 370-374 UBERON:0001465 denotes knee
T28 375-381 UBERON:0000982 denotes joints
T29 389-393 D004285 denotes dogs
T30 419-436 UBERON:0002018 denotes synovial membrane
T31 419-436 UBERON:0007616 denotes synovial membrane
T33 428-436 GO:0016020 denotes membrane
T35 558-562 PR:P15379 denotes CD44
T36 558-562 PR:P26051 denotes CD44
T37 558-562 PR:000001307 denotes CD44
T38 558-562 PR:P16070 denotes CD44
T39 567-571 PR:000001843 denotes CD90
T41 600-604 PR:000023297 denotes MSCs
T42 600-604 PR:P0C0S1 denotes MSCs
T40 600-604 GO:0043854 denotes MSCs
T43 750-764 GO:0051216 denotes chondrogenesis
T44 766-778 GO:0060612 denotes adipogenesis
T45 766-778 GO:0045444 denotes adipogenesis
T46 780-792 GO:0001503 denotes osteogenesis
T47 950-957 SO:0001031 denotes reverse
T48 950-971 P23072 denotes reverse transcriptase
T49 950-971 P21329 denotes reverse transcriptase
T50 950-971 P23071 denotes reverse transcriptase
T51 950-971 P21328 denotes reverse transcriptase
T53 950-971 P23070 denotes reverse transcriptase
T54 950-971 Q9NBX4 denotes reverse transcriptase
T55 950-971 Q95SX7 denotes reverse transcriptase
T52 950-971 D012194 denotes reverse transcriptase
T61 958-971 GO:0003968 denotes transcriptase
T139 958-971 GO:0003899 denotes transcriptase
T163 958-971 GO:0034062 denotes transcriptase
T180 983-988 SO:0000419 denotes chain
T181 983-997 MOP:0000635 denotes chain reaction
T183 1095-1099 PR:000023297 denotes MSCs
T184 1095-1099 PR:P0C0S1 denotes MSCs
T182 1095-1099 GO:0043854 denotes MSCs
T185 1124-1127 PR:P40238 denotes MPL
T187 1124-1127 PR:000023277 denotes MPL
T188 1124-1127 PR:000001939 denotes MPL
T189 1124-1127 PR:Q08351 denotes MPL
T190 1124-1127 PR:P37773 denotes MPL
T186 1124-1127 UBERON:0002662 denotes MPL
T191 1128-1136 UBERON:0002018 denotes synovium
T192 1128-1136 UBERON:0007616 denotes synovium
T193 1128-1136 UBERON:0011233 denotes synovium
T194 1210-1213 PR:P40238 denotes MPL
T196 1210-1213 PR:000023277 denotes MPL
T197 1210-1213 PR:000001939 denotes MPL
T198 1210-1213 PR:Q08351 denotes MPL
T199 1210-1213 PR:P37773 denotes MPL
T195 1210-1213 UBERON:0002662 denotes MPL
T200 1278-1294 CL:0000842 denotes mononuclear cell
T201 1321-1332 D006984 denotes hypertrophy
T202 1321-1332 D006984 denotes hypertrophy
T203 1370-1385 UBERON:0007616 denotes synovial tissue
T205 1394-1397 PR:P40238 denotes MPL
T207 1394-1397 PR:000023277 denotes MPL
T208 1394-1397 PR:000001939 denotes MPL
T209 1394-1397 PR:Q08351 denotes MPL
T210 1394-1397 PR:P37773 denotes MPL
T206 1394-1397 UBERON:0002662 denotes MPL
T211 1570-1575 UBERON:0004905 denotes joint
T212 1570-1575 UBERON:0000982 denotes joint

Inflammaging

Id Subject Object Predicate Lexical cue
T1 0-137 Sentence denotes Differentiation potential of synoviocytes derived from joints with cranial cruciate ligament rupture and medial patella luxation in dogs.
T2 138-280 Sentence denotes The objective of this study was to assess the differentiation capability of synoviocytes derived from dogs with inflammatory joint conditions.
T3 281-442 Sentence denotes Cranial cruciate ligament ruptured (CCLr) (n=12) and medial patella luxated (MPL) (n=10) knee joints of the dogs were used to collect the synovial membrane (SM).
T4 443-667 Sentence denotes Synoviocytes were enzymatically released from the SM and analyzed by flow cytometry for specific cellular markers (CD44 and CD90) of mesenchymal stem cells (MSCs), while doing histopathology from another part of SM sections.
T5 668-848 Sentence denotes Under specific culture conditions, synoviocytes were forced to differentiate into chondrogenesis, adipogenesis, osteogenesis and osteoclastogenesis to investigate the multipotency.
T6 849-1054 Sentence denotes Upon treatments phenotypes of cell cultures were analyzed by histopathology and by semi-quantitative reverse transcriptase polymerase chain reaction for the expression of each differentiation marker genes.
T7 1055-1230 Sentence denotes Although flow cytometry showing similar MSCs populations in CCLr and MPL synovium, synovial cells derived from CCLr showed higher multipotency compared to MPL-derived samples.
T8 1231-1398 Sentence denotes Further, synovial changes such as vascularity, mononuclear cell infiltration and cellular hypertrophy were more pronounced in CCLr-derived synovial tissue than in MPL.
T9 1399-1587 Sentence denotes Taken together, these findings suggested that the differentiation capability of SM-derived multipotent stem cells varies with inflammatory severity occurring in different joint conditions.
T1 0-137 Sentence denotes Differentiation potential of synoviocytes derived from joints with cranial cruciate ligament rupture and medial patella luxation in dogs.
T2 138-280 Sentence denotes The objective of this study was to assess the differentiation capability of synoviocytes derived from dogs with inflammatory joint conditions.
T3 281-442 Sentence denotes Cranial cruciate ligament ruptured (CCLr) (n=12) and medial patella luxated (MPL) (n=10) knee joints of the dogs were used to collect the synovial membrane (SM).
T4 443-667 Sentence denotes Synoviocytes were enzymatically released from the SM and analyzed by flow cytometry for specific cellular markers (CD44 and CD90) of mesenchymal stem cells (MSCs), while doing histopathology from another part of SM sections.
T5 668-848 Sentence denotes Under specific culture conditions, synoviocytes were forced to differentiate into chondrogenesis, adipogenesis, osteogenesis and osteoclastogenesis to investigate the multipotency.
T6 849-1054 Sentence denotes Upon treatments phenotypes of cell cultures were analyzed by histopathology and by semi-quantitative reverse transcriptase polymerase chain reaction for the expression of each differentiation marker genes.
T7 1055-1230 Sentence denotes Although flow cytometry showing similar MSCs populations in CCLr and MPL synovium, synovial cells derived from CCLr showed higher multipotency compared to MPL-derived samples.
T8 1231-1398 Sentence denotes Further, synovial changes such as vascularity, mononuclear cell infiltration and cellular hypertrophy were more pronounced in CCLr-derived synovial tissue than in MPL.
T9 1399-1587 Sentence denotes Taken together, these findings suggested that the differentiation capability of SM-derived multipotent stem cells varies with inflammatory severity occurring in different joint conditions.