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c_corpus

Id Subject Object Predicate Lexical cue
T12 0-5 PR:P35716 denotes SOX11
T13 0-5 PR:000015419 denotes SOX11
T14 0-5 PR:Q7M6Y2 denotes SOX11
T15 0-5 PR:P48435 denotes SOX11
T16 0-5 PR:P0C1G9 denotes SOX11
T17 15-30 GO:0036267 denotes invasive growth
T18 15-30 GO:0051831 denotes invasive growth
T19 15-30 GO:0044409 denotes invasive growth
T20 15-30 GO:0007125 denotes invasive growth
T21 15-30 GO:0044412 denotes invasive growth
T22 15-30 GO:0001404 denotes invasive growth
T25 35-59 D002285 denotes ductal carcinoma in situ
T26 35-59 D002285 denotes ductal carcinoma in situ
T42 92-97 PR:P35716 denotes SOX11
T43 92-97 PR:000015419 denotes SOX11
T44 92-97 PR:Q7M6Y2 denotes SOX11
T45 92-97 PR:P48435 denotes SOX11
T46 92-97 PR:P0C1G9 denotes SOX11
T47 102-111 P02301 denotes embryonic
T48 102-111 PR:000029532 denotes embryonic
T49 164-170 UBERON:0000310 denotes breast
T50 199-208 CHEBI:50114 denotes oestrogen
T53 239-263 D002285 denotes ductal carcinoma in situ
T54 239-263 D002285 denotes ductal carcinoma in situ
T60 265-269 CVCL_5552 denotes DCIS
T59 265-269 D002285 denotes DCIS
T61 265-269 D002285 denotes DCIS
T62 312-322 SO:0000783 denotes engineered
T74 334-339 PR:P35716 denotes SOX11
T75 334-339 PR:000015419 denotes SOX11
T76 334-339 PR:Q7M6Y2 denotes SOX11
T77 334-339 PR:P48435 denotes SOX11
T78 334-339 PR:P0C1G9 denotes SOX11
T80 450-472 P41751 denotes aldehyde dehydrogenase
T81 450-472 O74187 denotes aldehyde dehydrogenase
T82 450-472 A0A5C1REZ4 denotes aldehyde dehydrogenase
T83 450-472 P08157 denotes aldehyde dehydrogenase
T84 450-472 P45959 denotes aldehyde dehydrogenase
T85 450-472 P0C6D7 denotes aldehyde dehydrogenase
T86 450-472 Q27640 denotes aldehyde dehydrogenase
T87 450-472 P40108 denotes aldehyde dehydrogenase
T88 450-472 Q8GAK7 denotes aldehyde dehydrogenase
T89 450-472 P12693 denotes aldehyde dehydrogenase
T90 450-472 Q9RYG9 denotes aldehyde dehydrogenase
T91 450-472 Q9ZA11 denotes aldehyde dehydrogenase
T92 450-472 A1B4L2 denotes aldehyde dehydrogenase
T93 450-472 A5F3A7 denotes aldehyde dehydrogenase
T95 450-472 Q8VXQ2 denotes aldehyde dehydrogenase
T96 450-472 P42041 denotes aldehyde dehydrogenase
T94 450-472 D000444 denotes aldehyde dehydrogenase
T99 474-478 P23883 denotes ALDH
T100 474-478 P80472 denotes ALDH
T101 474-478 P41751 denotes ALDH
T102 474-478 O74187 denotes ALDH
T103 474-478 P08157 denotes ALDH
T104 474-478 P17201 denotes ALDH
T105 474-478 PR:P23883 denotes ALDH
T107 474-478 P40108 denotes ALDH
T108 474-478 PR:000023651 denotes ALDH
T109 474-478 P80705 denotes ALDH
T110 474-478 PR:P51647 denotes ALDH
T111 474-478 P80704 denotes ALDH
T112 474-478 P42041 denotes ALDH
T106 474-478 GO:0004030 denotes ALDH
T113 534-538 D002285 denotes DCIS
T115 534-538 D002285 denotes DCIS
T116 534-542 CVCL_5552 denotes DCIS.com
T117 539-542 CHEBI:17905 denotes com
T118 549-559 SO:0000783 denotes engineered
T130 571-576 PR:P35716 denotes SOX11
T131 571-576 PR:000015419 denotes SOX11
T132 571-576 PR:Q7M6Y2 denotes SOX11
T133 571-576 PR:P48435 denotes SOX11
T134 571-576 PR:P0C1G9 denotes SOX11
T135 594-598 P23883 denotes ALDH
T136 594-598 P80472 denotes ALDH
T137 594-598 P41751 denotes ALDH
T138 594-598 O74187 denotes ALDH
T139 594-598 P08157 denotes ALDH
T140 594-598 P17201 denotes ALDH
T141 594-598 PR:P23883 denotes ALDH
T143 594-598 P40108 denotes ALDH
T144 594-598 PR:000023651 denotes ALDH
T145 594-598 P80705 denotes ALDH
T146 594-598 PR:P51647 denotes ALDH
T147 594-598 P80704 denotes ALDH
T148 594-598 P42041 denotes ALDH
T142 594-598 GO:0004030 denotes ALDH
T149 654-658 PR:P15379 denotes CD44
T150 654-658 PR:P26051 denotes CD44
T151 654-658 PR:000001307 denotes CD44
T152 654-658 PR:P16070 denotes CD44
T153 660-664 PR:Q07490 denotes CD24
T154 660-664 PR:P25063 denotes CD24
T155 660-664 PR:000001932 denotes CD24
T156 660-664 PR:P24807 denotes CD24
T157 666-670 P23883 denotes ALDH
T158 666-670 P80472 denotes ALDH
T159 666-670 P41751 denotes ALDH
T160 666-670 O74187 denotes ALDH
T161 666-670 P08157 denotes ALDH
T162 666-670 P17201 denotes ALDH
T163 666-670 PR:P23883 denotes ALDH
T165 666-670 P40108 denotes ALDH
T166 666-670 PR:000023651 denotes ALDH
T167 666-670 P80705 denotes ALDH
T168 666-670 PR:P51647 denotes ALDH
T169 666-670 P80704 denotes ALDH
T170 666-670 P42041 denotes ALDH
T164 666-670 GO:0004030 denotes ALDH
T171 705-709 D002285 denotes DCIS
T173 705-709 D002285 denotes DCIS
T174 705-713 CVCL_5552 denotes DCIS.com
T175 710-713 CHEBI:17905 denotes com
T187 735-740 PR:P35716 denotes SOX11
T188 735-740 PR:000015419 denotes SOX11
T189 735-740 PR:Q7M6Y2 denotes SOX11
T190 735-740 PR:P48435 denotes SOX11
T191 735-740 PR:P0C1G9 denotes SOX11
T203 755-760 PR:P35716 denotes SOX11
T204 755-760 PR:000015419 denotes SOX11
T205 755-760 PR:Q7M6Y2 denotes SOX11
T206 755-760 PR:P48435 denotes SOX11
T207 755-760 PR:P0C1G9 denotes SOX11
T208 775-779 D002285 denotes DCIS
T210 775-779 D002285 denotes DCIS
T211 775-783 CVCL_5552 denotes DCIS.com
T212 780-783 CHEBI:17905 denotes com
T213 807-822 GO:0036267 denotes invasive growth
T214 807-822 GO:0051831 denotes invasive growth
T215 807-822 GO:0044409 denotes invasive growth
T216 807-822 GO:0007125 denotes invasive growth
T217 807-822 GO:0044412 denotes invasive growth
T218 807-822 GO:0001404 denotes invasive growth
T219 882-889 MGI:87853 denotes a mouse
T220 884-889 10090 denotes mouse
T221 884-889 D051379 denotes mouse
T223 899-903 CVCL_5552 denotes DCIS
T222 899-903 D002285 denotes DCIS
T224 899-903 D002285 denotes DCIS
T225 923-928 D006801 denotes human
T226 929-936 D004194 denotes disease
T227 929-936 D004194 denotes disease
T239 1026-1031 PR:P35716 denotes SOX11
T240 1026-1031 PR:000015419 denotes SOX11
T241 1026-1031 PR:Q7M6Y2 denotes SOX11
T242 1026-1031 PR:P48435 denotes SOX11
T243 1026-1031 PR:P0C1G9 denotes SOX11
T245 1066-1070 CVCL_5552 denotes DCIS
T244 1066-1070 D002285 denotes DCIS
T246 1066-1070 D002285 denotes DCIS
T247 1083-1089 UBERON:0000310 denotes breast
T248 1083-1096 D001943 denotes breast cancer
T249 1083-1096 D001943 denotes breast cancer
T250 1122-1132 SO:0001633 denotes downstream
T262 1146-1151 PR:P35716 denotes SOX11
T263 1146-1151 PR:000015419 denotes SOX11
T264 1146-1151 PR:Q7M6Y2 denotes SOX11
T265 1146-1151 PR:P48435 denotes SOX11
T266 1146-1151 PR:P0C1G9 denotes SOX11
T267 1257-1267 GO:0065007 denotes regulation
T268 1309-1329 GO:0048589 denotes developmental growth
T280 1357-1362 PR:P35716 denotes SOX11
T281 1357-1362 PR:000015419 denotes SOX11
T282 1357-1362 PR:Q7M6Y2 denotes SOX11
T283 1357-1362 PR:P48435 denotes SOX11
T284 1357-1362 PR:P0C1G9 denotes SOX11
T285 1378-1387 CHEBI:59163 denotes biomarker
T287 1392-1396 CVCL_5552 denotes DCIS
T286 1392-1396 D002285 denotes DCIS
T288 1392-1396 D002285 denotes DCIS
T289 1502-1508 UBERON:0000310 denotes breast
T290 1502-1515 D001943 denotes breast cancer
T291 1502-1515 D001943 denotes breast cancer
T292 1634-1639 PR:Q91ZZ5 denotes Great

UseCases_ArguminSci_Discourse

Id Subject Object Predicate Lexical cue
T1 0-72 DRI_Background denotes SOX11 promotes invasive growth and ductal carcinoma in situ progression.
T2 73-208 DRI_Outcome denotes Here, we show that SOX11, an embryonic mammary marker that is normally silent in postnatal breast cells, is expressed in many oestrogen
T3 209-238 Token_Label.OUTSIDE denotes receptor-negative preinvasive
T4 239-279 DRI_Outcome denotes ductal carcinoma in situ (DCIS) lesions.
T5 280-533 DRI_Background denotes Mature mammary epithelial cells engineered to express SOX11 showed alterations in progenitor cell populations, including an expanded basal-like population with increased aldehyde dehydrogenase (ALDH) activity, and increased mammosphere-forming capacity.
T6 534-649 DRI_Background denotes DCIS.com cells engineered to express SOX11 showed increased ALDH activity, which is a feature of cancer stem cells.
T7 650-741 DRI_Background denotes The CD44+/CD24-/ALDH+ cell population was increased in DCIS.com cells that expressed SOX11.
T8 742-754 REPLACED denotes Upregulating
T9 755-760 Token_Label.OUTSIDE denotes SOX11
T10 761-937 DRI_Outcome denotes expression in DCIS.com cells led to increased invasive growth both in vitro and when they were injected intraductally in a mouse model of DCIS that recapitulates human disease.
T11 938-1097 DRI_Background denotes Invasive lesions formed sooner and tumour growth was augmented in vivo, suggesting that SOX11 contributes to the progression of DCIS to invasive breast cancer.
T12 1098-1330 DRI_Outcome denotes We identified potential downstream effectors of SOX11 during both microinvasive and invasive tumour growth stages, including several with established links to regulation of progenitor cell function and prenatal developmental growth.
T13 1331-1516 DRI_Outcome denotes Our findings suggest that SOX11 is a potential biomarker for DCIS lesions containing cells harbouring distinct biological features that are likely to progress to invasive breast cancer.
T14 1517-1536 DRI_Unspecified denotes © 2017 The Authors.
T15 1537-1660 DRI_Background denotes The Journal of Pathology published by John Wiley & Sons Ltd on behalf of Pathological Society of Great Britain and Ireland.

PubMed_ArguminSci

Id Subject Object Predicate Lexical cue
T1 73-208 DRI_Outcome denotes Here, we show that SOX11, an embryonic mammary marker that is normally silent in postnatal breast cells, is expressed in many oestrogen
T2 239-279 DRI_Outcome denotes ductal carcinoma in situ (DCIS) lesions.
T3 280-533 DRI_Background denotes Mature mammary epithelial cells engineered to express SOX11 showed alterations in progenitor cell populations, including an expanded basal-like population with increased aldehyde dehydrogenase (ALDH) activity, and increased mammosphere-forming capacity.
T4 534-649 DRI_Background denotes DCIS.com cells engineered to express SOX11 showed increased ALDH activity, which is a feature of cancer stem cells.
T5 650-741 DRI_Background denotes The CD44+/CD24-/ALDH+ cell population was increased in DCIS.com cells that expressed SOX11.
T6 742-754 REPLACED denotes Upregulating
T7 761-937 DRI_Outcome denotes expression in DCIS.com cells led to increased invasive growth both in vitro and when they were injected intraductally in a mouse model of DCIS that recapitulates human disease.
T8 938-1097 DRI_Background denotes Invasive lesions formed sooner and tumour growth was augmented in vivo, suggesting that SOX11 contributes to the progression of DCIS to invasive breast cancer.
T9 1098-1330 DRI_Outcome denotes We identified potential downstream effectors of SOX11 during both microinvasive and invasive tumour growth stages, including several with established links to regulation of progenitor cell function and prenatal developmental growth.
T10 1331-1516 DRI_Outcome denotes Our findings suggest that SOX11 is a potential biomarker for DCIS lesions containing cells harbouring distinct biological features that are likely to progress to invasive breast cancer.
T11 1537-1660 DRI_Background denotes The Journal of Pathology published by John Wiley & Sons Ltd on behalf of Pathological Society of Great Britain and Ireland.