PubMed:28624519 / 0-778
Annnotations
{"target":"https://pubannotation.org/docs/sourcedb/PubMed/sourceid/28624519","sourcedb":"PubMed","sourceid":"28624519","text":"iTRAQ-based quantitative proteomics analysis of molecular mechanisms associated with Bombyx mori (Lepidoptera) larval midgut response to BmNPV in susceptible and near-isogenic strains.\nBombyx mori nucleopolyhedrovirus (BmNPV) has been identified as a major pathogen responsible for severe economic loss. Most silkworm strains are susceptible to BmNPV, with only a few highly resistant strains thus far identified. Here we investigated the molecular basis of silkworm resistance to BmNPV using susceptible (the recurrent parent P50) and resistant (near-isogenic line BC9) strains and a combination of iTRAQ-based quantitative proteomics, reverse-transcription quantitative PCR and Western blotting. By comparing the proteomes of infected and non-infected P50 and BC9 silkworms, w","tracks":[{"project":"sentences","denotations":[{"id":"T1","span":{"begin":0,"end":184},"obj":"Sentence"},{"id":"T2","span":{"begin":185,"end":303},"obj":"Sentence"},{"id":"T3","span":{"begin":304,"end":413},"obj":"Sentence"},{"id":"T4","span":{"begin":414,"end":697},"obj":"Sentence"},{"id":"T1","span":{"begin":0,"end":184},"obj":"Sentence"},{"id":"T2","span":{"begin":185,"end":303},"obj":"Sentence"},{"id":"T3","span":{"begin":304,"end":413},"obj":"Sentence"},{"id":"T4","span":{"begin":414,"end":697},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"attributes":[{"subj":"T1","pred":"source","obj":"sentences"},{"subj":"T2","pred":"source","obj":"sentences"},{"subj":"T3","pred":"source","obj":"sentences"},{"subj":"T4","pred":"source","obj":"sentences"},{"subj":"T1","pred":"source","obj":"sentences"},{"subj":"T2","pred":"source","obj":"sentences"},{"subj":"T3","pred":"source","obj":"sentences"},{"subj":"T4","pred":"source","obj":"sentences"}]},{"project":"silkworm","denotations":[{"id":"T1","span":{"begin":85,"end":96},"obj":"Species:7091"},{"id":"T2","span":{"begin":137,"end":142},"obj":"Species:271108"},{"id":"T3","span":{"begin":185,"end":217},"obj":"Species:271108"},{"id":"T4","span":{"begin":219,"end":224},"obj":"Species:271108"},{"id":"T5","span":{"begin":309,"end":317},"obj":"Species:7091"},{"id":"T6","span":{"begin":345,"end":350},"obj":"Species:271108"},{"id":"T7","span":{"begin":458,"end":466},"obj":"Species:7091"},{"id":"T8","span":{"begin":481,"end":486},"obj":"Species:271108"},{"id":"T9","span":{"begin":766,"end":775},"obj":"Species:7091"}],"attributes":[{"subj":"T1","pred":"source","obj":"silkworm"},{"subj":"T2","pred":"source","obj":"silkworm"},{"subj":"T3","pred":"source","obj":"silkworm"},{"subj":"T4","pred":"source","obj":"silkworm"},{"subj":"T5","pred":"source","obj":"silkworm"},{"subj":"T6","pred":"source","obj":"silkworm"},{"subj":"T7","pred":"source","obj":"silkworm"},{"subj":"T8","pred":"source","obj":"silkworm"},{"subj":"T9","pred":"source","obj":"silkworm"}]},{"project":"silkwormbase","denotations":[{"id":"T1","span":{"begin":85,"end":96},"obj":"Species:7091"},{"id":"T2","span":{"begin":137,"end":142},"obj":"Species:271108"},{"id":"T3","span":{"begin":185,"end":217},"obj":"Species:271108"},{"id":"T4","span":{"begin":219,"end":224},"obj":"Species:271108"},{"id":"T5","span":{"begin":309,"end":317},"obj":"Species:7091"},{"id":"T6","span":{"begin":345,"end":350},"obj":"Species:271108"},{"id":"T7","span":{"begin":458,"end":466},"obj":"Species:7091"},{"id":"T8","span":{"begin":481,"end":486},"obj":"Species:271108"},{"id":"T9","span":{"begin":766,"end":775},"obj":"Species:7091"}],"attributes":[{"subj":"T1","pred":"source","obj":"silkwormbase"},{"subj":"T2","pred":"source","obj":"silkwormbase"},{"subj":"T3","pred":"source","obj":"silkwormbase"},{"subj":"T4","pred":"source","obj":"silkwormbase"},{"subj":"T5","pred":"source","obj":"silkwormbase"},{"subj":"T6","pred":"source","obj":"silkwormbase"},{"subj":"T7","pred":"source","obj":"silkwormbase"},{"subj":"T8","pred":"source","obj":"silkwormbase"},{"subj":"T9","pred":"source","obj":"silkwormbase"}]},{"project":"NCBITAXON","denotations":[{"id":"T1","span":{"begin":85,"end":96},"obj":"OrganismTaxon"},{"id":"T2","span":{"begin":98,"end":109},"obj":"OrganismTaxon"},{"id":"T3","span":{"begin":137,"end":142},"obj":"OrganismTaxon"},{"id":"T4","span":{"begin":185,"end":217},"obj":"OrganismTaxon"},{"id":"T5","span":{"begin":219,"end":224},"obj":"OrganismTaxon"},{"id":"T6","span":{"begin":309,"end":317},"obj":"OrganismTaxon"},{"id":"T7","span":{"begin":345,"end":350},"obj":"OrganismTaxon"},{"id":"T8","span":{"begin":458,"end":466},"obj":"OrganismTaxon"},{"id":"T9","span":{"begin":481,"end":486},"obj":"OrganismTaxon"},{"id":"T10","span":{"begin":766,"end":775},"obj":"OrganismTaxon"}],"attributes":[{"id":"A1","pred":"db_id","subj":"T1","obj":"7091"},{"id":"A2","pred":"db_id","subj":"T2","obj":"7088"},{"id":"A3","pred":"db_id","subj":"T3","obj":"271108"},{"id":"A4","pred":"db_id","subj":"T4","obj":"271108"},{"id":"A5","pred":"db_id","subj":"T5","obj":"271108"},{"id":"A6","pred":"db_id","subj":"T6","obj":"7091"},{"id":"A7","pred":"db_id","subj":"T7","obj":"271108"},{"id":"A8","pred":"db_id","subj":"T8","obj":"7091"},{"id":"A9","pred":"db_id","subj":"T9","obj":"271108"},{"id":"A10","pred":"db_id","subj":"T10","obj":"7091"},{"subj":"T1","pred":"source","obj":"NCBITAXON"},{"subj":"T2","pred":"source","obj":"NCBITAXON"},{"subj":"T3","pred":"source","obj":"NCBITAXON"},{"subj":"T4","pred":"source","obj":"NCBITAXON"},{"subj":"T5","pred":"source","obj":"NCBITAXON"},{"subj":"T6","pred":"source","obj":"NCBITAXON"},{"subj":"T7","pred":"source","obj":"NCBITAXON"},{"subj":"T8","pred":"source","obj":"NCBITAXON"},{"subj":"T9","pred":"source","obj":"NCBITAXON"},{"subj":"T10","pred":"source","obj":"NCBITAXON"}]},{"project":"Anatomy-UBERON","denotations":[{"id":"T1","span":{"begin":118,"end":124},"obj":"Body_part"}],"attributes":[{"id":"A1","pred":"uberon_id","subj":"T1","obj":"http://purl.obolibrary.org/obo/UBERON_0001045"},{"subj":"T1","pred":"source","obj":"Anatomy-UBERON"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"sentences","color":"#93ceec","default":true},{"id":"silkworm","color":"#e8ec93"},{"id":"silkwormbase","color":"#d593ec"},{"id":"NCBITAXON","color":"#93ecbb"},{"id":"Anatomy-UBERON","color":"#eca193"}]}]}}