PubMed:28580974 JSONTXT

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{"target":"http://pubannotation.org/docs/sourcedb/PubMed/sourceid/28580974","sourcedb":"PubMed","sourceid":"28580974","text":"Stereoselective synthesis of enamino ketones through an aza-Michael/hydrolysis cascade reaction.\nWe have developed a mild, convenient and efficient synthesis of highly functionalized (Z)-β-enamino ketones from readily available 3,4-dihydroisoquinoline imines and ynones through an aza-Michael/hydrolysis cascade reaction. This method is also suitable for the preparation of (Z)-β-enamino esters using alkynoates as starting materials. Complex fully substituted pyrroles can be constructed from the obtained (Z)-β-enamino ketones. It is an attractive alternative approach for the preparation of highly functionalized enamino ketones, esters and pyrroles.","tracks":[]}