PubMed:28518143
Annnotations
LitCoin-entities-OrganismTaxon-PD
Id | Subject | Object | Predicate | Lexical cue | db_id |
---|---|---|---|---|---|
T1 | 554-558 | OrganismTaxon | denotes | rats | NCBItxid:10118|NCBItxid:10116|NCBItxid:10114 |
LitCoin-sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T10 | 1419-1590 | Sentence | denotes | In turn, these effects disrupt the structure and function of the mitochondria and the cell gap junction, result in the reduced ATP synthesis and the increased ATP leakage. |
T11 | 1591-1760 | Sentence | denotes | Stimulation of CaSR significantly attenuates HG-induced abnormal myocardial energy metabolism, suggesting CaSR would be a promising potential therapeutic target for DCM. |
T7 | 981-1162 | Sentence | denotes | In contrast, HG increased extracellular ATP concentration, the expression of gp78, mitochondrial fission proteins (Fis1, Drp1), and the ubiquitination levels of Mfn1, Mfn2 and Cx43. |
T8 | 1163-1241 | Sentence | denotes | Moreover, CaSR agonist and gp78-siRNA significantly reduced the above changes. |
T9 | 1242-1418 | Sentence | denotes | Taken together, these results suggest that HG induces myocardial energy metabolism disorder via decrease of CaSR expression, and activation of gp78-ubiquitin proteasome system. |
T1 | 0-129 | Sentence | denotes | Calcium sensing receptor protects high glucose-induced energy metabolism disorder via blocking gp78-ubiquitin proteasome pathway. |
T2 | 130-230 | Sentence | denotes | Diabetic cardiomyopathy (DCM) is a major complication and fatal cause of the patients with diabetes. |
T3 | 231-409 | Sentence | denotes | The calcium sensing receptor (CaSR) is a G protein-coupled receptor, which is involved in maintaining calcium homeostasis, regulating cell proliferation and apoptosis, and so on. |
T4 | 410-607 | Sentence | denotes | In our previous study, we found that CaSR expression, intracellular calcium levels and cardiac function were all significantly decreased in DCM rats; however, the exact mechanism are not clear yet. |
T5 | 608-769 | Sentence | denotes | The present study revealed the protective role of CaSR in myocardial energy metabolism disorder induced by high glucose (HG) as well as the underlying mechanism. |
T6 | 770-980 | Sentence | denotes | Here, we demonstrated that HG decreased the expression of CaSR, mitochondrial fusion proteins (Mfn1, Mfn2), cell gap junction related proteins (Cx43, β-catenin, N-cadherin), and intracellular ATP concentration. |
LitCoin-entities
Id | Subject | Object | Predicate | Lexical cue | db_id |
---|---|---|---|---|---|
13003 | 0-24 | GeneOrGeneProduct | denotes | Calcium sensing receptor | NCBIGene:24247 |
13004 | 39-46 | ChemicalEntity | denotes | glucose | MESH:D005947 |
13005 | 62-81 | DiseaseOrPhenotypicFeature | denotes | metabolism disorder | MESH:D008659 |
13006 | 95-99 | GeneOrGeneProduct | denotes | gp78 | NCBIGene:361367 |
13007 | 130-153 | DiseaseOrPhenotypicFeature | denotes | Diabetic cardiomyopathy | MESH:D058065 |
13008 | 155-158 | DiseaseOrPhenotypicFeature | denotes | DCM | MESH:D002311 |
13009 | 207-215 | OrganismTaxon | denotes | patients | NCBITaxon:9606 |
13010 | 221-229 | DiseaseOrPhenotypicFeature | denotes | diabetes | MESH:D003920 |
13011 | 235-259 | GeneOrGeneProduct | denotes | calcium sensing receptor | NCBIGene:24247 |
13012 | 261-265 | GeneOrGeneProduct | denotes | CaSR | NCBIGene:24247 |
13013 | 272-298 | GeneOrGeneProduct | denotes | G protein-coupled receptor | NCBIGene:24247 |
13014 | 333-340 | ChemicalEntity | denotes | calcium | MESH:D002118 |
13015 | 447-451 | GeneOrGeneProduct | denotes | CaSR | NCBIGene:24247 |
13016 | 478-485 | ChemicalEntity | denotes | calcium | MESH:D002118 |
13017 | 550-553 | DiseaseOrPhenotypicFeature | denotes | DCM | MESH:D002311 |
13018 | 554-558 | OrganismTaxon | denotes | rats | NCBITaxon:10116 |
13019 | 658-662 | GeneOrGeneProduct | denotes | CaSR | NCBIGene:24247 |
13020 | 666-703 | DiseaseOrPhenotypicFeature | denotes | myocardial energy metabolism disorder | MESH:D009202 |
13021 | 720-727 | ChemicalEntity | denotes | glucose | MESH:D005947 |
13022 | 828-832 | GeneOrGeneProduct | denotes | CaSR | NCBIGene:24247 |
13023 | 865-869 | GeneOrGeneProduct | denotes | Mfn1 | NCBIGene:192647 |
13024 | 871-875 | GeneOrGeneProduct | denotes | Mfn2 | NCBIGene:64476 |
13025 | 914-918 | GeneOrGeneProduct | denotes | Cx43 | NCBIGene:24392 |
13026 | 920-929 | GeneOrGeneProduct | denotes | β-catenin | NCBIGene:84353 |
13027 | 931-941 | GeneOrGeneProduct | denotes | N-cadherin | NCBIGene:83501 |
13028 | 962-965 | ChemicalEntity | denotes | ATP | MESH:D000255 |
13029 | 1021-1024 | ChemicalEntity | denotes | ATP | MESH:D000255 |
13030 | 1058-1062 | GeneOrGeneProduct | denotes | gp78 | NCBIGene:361367 |
13031 | 1096-1100 | GeneOrGeneProduct | denotes | Fis1 | NCBIGene:288584 |
13032 | 1102-1106 | GeneOrGeneProduct | denotes | Drp1 | NCBIGene:114114 |
13033 | 1142-1146 | GeneOrGeneProduct | denotes | Mfn1 | NCBIGene:192647 |
13034 | 1148-1152 | GeneOrGeneProduct | denotes | Mfn2 | NCBIGene:64476 |
13035 | 1157-1161 | GeneOrGeneProduct | denotes | Cx43 | NCBIGene:24392 |
13036 | 1173-1177 | GeneOrGeneProduct | denotes | CaSR | NCBIGene:24247 |
13037 | 1190-1194 | GeneOrGeneProduct | denotes | gp78 | NCBIGene:361367 |
13038 | 1296-1333 | DiseaseOrPhenotypicFeature | denotes | myocardial energy metabolism disorder | MESH:D009202 |
13039 | 1350-1354 | GeneOrGeneProduct | denotes | CaSR | NCBIGene:24247 |
13040 | 1385-1389 | GeneOrGeneProduct | denotes | gp78 | NCBIGene:361367 |
13041 | 1546-1549 | ChemicalEntity | denotes | ATP | MESH:D000255 |
13042 | 1578-1581 | ChemicalEntity | denotes | ATP | MESH:D000255 |
13043 | 1606-1610 | GeneOrGeneProduct | denotes | CaSR | NCBIGene:24247 |
13044 | 1647-1684 | DiseaseOrPhenotypicFeature | denotes | abnormal myocardial energy metabolism | MESH:D009202 |
13045 | 1697-1701 | GeneOrGeneProduct | denotes | CaSR | NCBIGene:24247 |
13046 | 1756-1759 | DiseaseOrPhenotypicFeature | denotes | DCM | MESH:D002311 |
LitCoin_Mondo
Id | Subject | Object | Predicate | Lexical cue | mondo_id |
---|---|---|---|---|---|
T1 | 139-153 | DiseaseOrPhenotypicFeature | denotes | cardiomyopathy | 0004994 |
LitCoin-GeneOrGeneProduct-v0
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 16-24 | GeneOrGeneProduct | denotes | receptor |
T2 | 34-38 | GeneOrGeneProduct | denotes | high |
T3 | 47-54 | GeneOrGeneProduct | denotes | induced |
T4 | 86-94 | GeneOrGeneProduct | denotes | blocking |
T5 | 95-99 | GeneOrGeneProduct | denotes | gp78 |
T6 | 100-109 | GeneOrGeneProduct | denotes | ubiquitin |
T7 | 110-120 | GeneOrGeneProduct | denotes | proteasome |
T8 | 130-138 | GeneOrGeneProduct | denotes | Diabetic |
T9 | 155-158 | GeneOrGeneProduct | denotes | DCM |
T10 | 165-170 | GeneOrGeneProduct | denotes | major |
T11 | 221-229 | GeneOrGeneProduct | denotes | diabetes |
T12 | 235-259 | GeneOrGeneProduct | denotes | calcium sensing receptor |
T13 | 261-265 | GeneOrGeneProduct | denotes | CaSR |
T14 | 272-298 | GeneOrGeneProduct | denotes | G protein-coupled receptor |
T15 | 333-364 | GeneOrGeneProduct | denotes | calcium homeostasis, regulating |
T16 | 365-369 | GeneOrGeneProduct | denotes | cell |
T17 | 388-397 | GeneOrGeneProduct | denotes | apoptosis |
T18 | 447-451 | GeneOrGeneProduct | denotes | CaSR |
T19 | 478-492 | GeneOrGeneProduct | denotes | calcium levels |
T20 | 519-522 | GeneOrGeneProduct | denotes | all |
T21 | 550-553 | GeneOrGeneProduct | denotes | DCM |
T22 | 658-662 | GeneOrGeneProduct | denotes | CaSR |
T23 | 704-711 | GeneOrGeneProduct | denotes | induced |
T24 | 715-719 | GeneOrGeneProduct | denotes | high |
T25 | 828-832 | GeneOrGeneProduct | denotes | CaSR |
T26 | 834-847 | GeneOrGeneProduct | denotes | mitochondrial |
T27 | 848-854 | GeneOrGeneProduct | denotes | fusion |
T28 | 855-863 | GeneOrGeneProduct | denotes | proteins |
T29 | 865-869 | GeneOrGeneProduct | denotes | Mfn1 |
T30 | 871-875 | GeneOrGeneProduct | denotes | Mfn2 |
T31 | 878-882 | GeneOrGeneProduct | denotes | cell |
T32 | 896-912 | GeneOrGeneProduct | denotes | related proteins |
T33 | 914-918 | GeneOrGeneProduct | denotes | Cx43 |
T34 | 922-929 | GeneOrGeneProduct | denotes | catenin |
T35 | 931-941 | GeneOrGeneProduct | denotes | N-cadherin |
T36 | 962-965 | GeneOrGeneProduct | denotes | ATP |
T37 | 984-992 | GeneOrGeneProduct | denotes | contrast |
T38 | 1007-1020 | GeneOrGeneProduct | denotes | extracellular |
T39 | 1021-1024 | GeneOrGeneProduct | denotes | ATP |
T40 | 1058-1062 | GeneOrGeneProduct | denotes | gp78 |
T41 | 1064-1077 | GeneOrGeneProduct | denotes | mitochondrial |
T42 | 1086-1094 | GeneOrGeneProduct | denotes | proteins |
T43 | 1096-1100 | GeneOrGeneProduct | denotes | Fis1 |
T44 | 1102-1106 | GeneOrGeneProduct | denotes | Drp1 |
T45 | 1117-1131 | GeneOrGeneProduct | denotes | ubiquitination |
T46 | 1142-1146 | GeneOrGeneProduct | denotes | Mfn1 |
T47 | 1148-1152 | GeneOrGeneProduct | denotes | Mfn2 |
T48 | 1157-1161 | GeneOrGeneProduct | denotes | Cx43 |
T49 | 1173-1177 | GeneOrGeneProduct | denotes | CaSR |
T50 | 1190-1194 | GeneOrGeneProduct | denotes | gp78 |
T51 | 1215-1222 | GeneOrGeneProduct | denotes | reduced |
T52 | 1288-1295 | GeneOrGeneProduct | denotes | induces |
T53 | 1350-1354 | GeneOrGeneProduct | denotes | CaSR |
T54 | 1371-1381 | GeneOrGeneProduct | denotes | activation |
T55 | 1385-1389 | GeneOrGeneProduct | denotes | gp78 |
T56 | 1390-1399 | GeneOrGeneProduct | denotes | ubiquitin |
T57 | 1400-1410 | GeneOrGeneProduct | denotes | proteasome |
T58 | 1442-1449 | GeneOrGeneProduct | denotes | disrupt |
T59 | 1484-1496 | GeneOrGeneProduct | denotes | mitochondria |
T60 | 1505-1509 | GeneOrGeneProduct | denotes | cell |
T61 | 1538-1545 | GeneOrGeneProduct | denotes | reduced |
T62 | 1546-1549 | GeneOrGeneProduct | denotes | ATP |
T63 | 1578-1581 | GeneOrGeneProduct | denotes | ATP |
T64 | 1606-1610 | GeneOrGeneProduct | denotes | CaSR |
T65 | 1625-1635 | GeneOrGeneProduct | denotes | attenuates |
T66 | 1639-1646 | GeneOrGeneProduct | denotes | induced |
T67 | 1697-1701 | GeneOrGeneProduct | denotes | CaSR |
T68 | 1756-1759 | GeneOrGeneProduct | denotes | DCM |
LitCoin-GeneOrGeneProduct-v2
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 16-24 | GeneOrGeneProduct | denotes | receptor |
T2 | 34-38 | GeneOrGeneProduct | denotes | high |
T3 | 95-99 | GeneOrGeneProduct | denotes | gp78 |
T4 | 100-109 | GeneOrGeneProduct | denotes | ubiquitin |
T5 | 110-120 | GeneOrGeneProduct | denotes | proteasome |
T6 | 165-170 | GeneOrGeneProduct | denotes | major |
T7 | 221-229 | GeneOrGeneProduct | denotes | diabetes |
T8 | 235-259 | GeneOrGeneProduct | denotes | calcium sensing receptor |
T9 | 261-265 | GeneOrGeneProduct | denotes | CaSR |
T10 | 272-298 | GeneOrGeneProduct | denotes | G protein-coupled receptor |
T11 | 333-364 | GeneOrGeneProduct | denotes | calcium homeostasis, regulating |
T12 | 365-369 | GeneOrGeneProduct | denotes | cell |
T13 | 388-397 | GeneOrGeneProduct | denotes | apoptosis |
T14 | 447-451 | GeneOrGeneProduct | denotes | CaSR |
T15 | 478-492 | GeneOrGeneProduct | denotes | calcium levels |
T16 | 658-662 | GeneOrGeneProduct | denotes | CaSR |
T17 | 715-719 | GeneOrGeneProduct | denotes | high |
T18 | 828-832 | GeneOrGeneProduct | denotes | CaSR |
T19 | 834-847 | GeneOrGeneProduct | denotes | mitochondrial |
T20 | 848-854 | GeneOrGeneProduct | denotes | fusion |
T21 | 865-869 | GeneOrGeneProduct | denotes | Mfn1 |
T22 | 871-875 | GeneOrGeneProduct | denotes | Mfn2 |
T23 | 878-882 | GeneOrGeneProduct | denotes | cell |
T24 | 896-912 | GeneOrGeneProduct | denotes | related proteins |
T25 | 914-918 | GeneOrGeneProduct | denotes | Cx43 |
T26 | 922-929 | GeneOrGeneProduct | denotes | catenin |
T27 | 931-941 | GeneOrGeneProduct | denotes | N-cadherin |
T28 | 1007-1020 | GeneOrGeneProduct | denotes | extracellular |
T29 | 1058-1062 | GeneOrGeneProduct | denotes | gp78 |
T30 | 1064-1077 | GeneOrGeneProduct | denotes | mitochondrial |
T31 | 1096-1100 | GeneOrGeneProduct | denotes | Fis1 |
T32 | 1102-1106 | GeneOrGeneProduct | denotes | Drp1 |
T33 | 1142-1146 | GeneOrGeneProduct | denotes | Mfn1 |
T34 | 1148-1152 | GeneOrGeneProduct | denotes | Mfn2 |
T35 | 1157-1161 | GeneOrGeneProduct | denotes | Cx43 |
T36 | 1173-1177 | GeneOrGeneProduct | denotes | CaSR |
T37 | 1190-1194 | GeneOrGeneProduct | denotes | gp78 |
T38 | 1215-1222 | GeneOrGeneProduct | denotes | reduced |
T39 | 1350-1354 | GeneOrGeneProduct | denotes | CaSR |
T40 | 1385-1389 | GeneOrGeneProduct | denotes | gp78 |
T41 | 1390-1399 | GeneOrGeneProduct | denotes | ubiquitin |
T42 | 1400-1410 | GeneOrGeneProduct | denotes | proteasome |
T43 | 1484-1496 | GeneOrGeneProduct | denotes | mitochondria |
T44 | 1505-1509 | GeneOrGeneProduct | denotes | cell |
T45 | 1538-1545 | GeneOrGeneProduct | denotes | reduced |
T46 | 1606-1610 | GeneOrGeneProduct | denotes | CaSR |
T47 | 1697-1701 | GeneOrGeneProduct | denotes | CaSR |
LitCoin-Disease-MeSH
Id | Subject | Object | Predicate | Lexical cue | originalLabel |
---|---|---|---|---|---|
T1 | 130-153 | DiseaseOrPhenotypicFeature | denotes | Diabetic cardiomyopathy | D058065 |
T2 | 155-158 | DiseaseOrPhenotypicFeature | denotes | DCM | D058065 |
T3 | 221-229 | DiseaseOrPhenotypicFeature | denotes | diabetes | DISEASE |
T4 | 550-553 | DiseaseOrPhenotypicFeature | denotes | DCM | D058065 |
T5 | 1756-1759 | DiseaseOrPhenotypicFeature | denotes | DCM | D058065 |
LitCoin-GeneOrGeneProduct-v3
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 0-24 | GeneOrGeneProduct | denotes | Calcium sensing receptor |
T2 | 95-99 | GeneOrGeneProduct | denotes | gp78 |
T3 | 100-109 | GeneOrGeneProduct | denotes | ubiquitin |
T4 | 110-120 | GeneOrGeneProduct | denotes | proteasome |
T5 | 235-259 | GeneOrGeneProduct | denotes | calcium sensing receptor |
T6 | 261-265 | GeneOrGeneProduct | denotes | CaSR |
T7 | 272-298 | GeneOrGeneProduct | denotes | G protein-coupled receptor |
T8 | 333-364 | GeneOrGeneProduct | denotes | calcium homeostasis, regulating |
T9 | 447-451 | GeneOrGeneProduct | denotes | CaSR |
T10 | 658-662 | GeneOrGeneProduct | denotes | CaSR |
T11 | 828-832 | GeneOrGeneProduct | denotes | CaSR |
T12 | 834-863 | GeneOrGeneProduct | denotes | mitochondrial fusion proteins |
T13 | 865-869 | GeneOrGeneProduct | denotes | Mfn1 |
T14 | 871-875 | GeneOrGeneProduct | denotes | Mfn2 |
T15 | 914-918 | GeneOrGeneProduct | denotes | Cx43 |
T16 | 922-929 | GeneOrGeneProduct | denotes | catenin |
T17 | 931-941 | GeneOrGeneProduct | denotes | N-cadherin |
T18 | 1058-1062 | GeneOrGeneProduct | denotes | gp78 |
T19 | 1064-1094 | GeneOrGeneProduct | denotes | mitochondrial fission proteins |
T20 | 1096-1100 | GeneOrGeneProduct | denotes | Fis1 |
T21 | 1102-1106 | GeneOrGeneProduct | denotes | Drp1 |
T22 | 1142-1146 | GeneOrGeneProduct | denotes | Mfn1 |
T23 | 1148-1152 | GeneOrGeneProduct | denotes | Mfn2 |
T24 | 1157-1161 | GeneOrGeneProduct | denotes | Cx43 |
T25 | 1173-1177 | GeneOrGeneProduct | denotes | CaSR |
T26 | 1190-1194 | GeneOrGeneProduct | denotes | gp78 |
T27 | 1350-1354 | GeneOrGeneProduct | denotes | CaSR |
T28 | 1385-1389 | GeneOrGeneProduct | denotes | gp78 |
T29 | 1390-1399 | GeneOrGeneProduct | denotes | ubiquitin |
T30 | 1400-1410 | GeneOrGeneProduct | denotes | proteasome |
T31 | 1606-1610 | GeneOrGeneProduct | denotes | CaSR |
T32 | 1697-1701 | GeneOrGeneProduct | denotes | CaSR |
LitCoin_Mondo_095
Id | Subject | Object | Predicate | Lexical cue | mondo_id |
---|---|---|---|---|---|
T1 | 139-153 | DiseaseOrPhenotypicFeature | denotes | cardiomyopathy | 0004994 |
T2 | 155-158 | DiseaseOrPhenotypicFeature | denotes | DCM | 0019315|0016333 |
T4 | 221-229 | DiseaseOrPhenotypicFeature | denotes | diabetes | 0005015 |
T5 | 550-553 | DiseaseOrPhenotypicFeature | denotes | DCM | 0019315|0016333 |
T7 | 1756-1759 | DiseaseOrPhenotypicFeature | denotes | DCM | 0019315|0016333 |
LitCoin-MeSH-Disease-2
Id | Subject | Object | Predicate | Lexical cue | ID: |
---|---|---|---|---|---|
T1 | 62-81 | DiseaseOrPhenotypicFeature | denotes | metabolism disorder | DISEASE |
T2 | 130-153 | DiseaseOrPhenotypicFeature | denotes | Diabetic cardiomyopathy | D058065 |
T3 | 155-158 | DiseaseOrPhenotypicFeature | denotes | DCM | D058065 |
T4 | 221-229 | DiseaseOrPhenotypicFeature | denotes | diabetes | DISEASE |
T5 | 550-553 | DiseaseOrPhenotypicFeature | denotes | DCM | D058065 |
T6 | 666-703 | DiseaseOrPhenotypicFeature | denotes | myocardial energy metabolism disorder | DISEASE |
T7 | 1296-1333 | DiseaseOrPhenotypicFeature | denotes | myocardial energy metabolism disorder | DISEASE |
T8 | 1647-1684 | DiseaseOrPhenotypicFeature | denotes | abnormal myocardial energy metabolism | DISEASE |
T9 | 1756-1759 | DiseaseOrPhenotypicFeature | denotes | DCM | D058065 |
LitCoin-MONDO_bioort2019
Id | Subject | Object | Predicate | Lexical cue | #label |
---|---|---|---|---|---|
T1 | 62-81 | DiseaseOrPhenotypicFeature | denotes | metabolism disorder | DISEASE |
T2 | 130-153 | DiseaseOrPhenotypicFeature | denotes | Diabetic cardiomyopathy | D058065 |
T3 | 155-158 | DiseaseOrPhenotypicFeature | denotes | DCM | D058065 |
T4 | 221-229 | DiseaseOrPhenotypicFeature | denotes | diabetes | DISEASE |
T5 | 550-553 | DiseaseOrPhenotypicFeature | denotes | DCM | D058065 |
T6 | 666-703 | DiseaseOrPhenotypicFeature | denotes | myocardial energy metabolism disorder | DISEASE |
T7 | 1296-1333 | DiseaseOrPhenotypicFeature | denotes | myocardial energy metabolism disorder | DISEASE |
T8 | 1647-1684 | DiseaseOrPhenotypicFeature | denotes | abnormal myocardial energy metabolism | DISEASE |
T9 | 1756-1759 | DiseaseOrPhenotypicFeature | denotes | DCM | D058065 |
LitCoin-Chemical-MeSH-CHEBI
Id | Subject | Object | Predicate | Lexical cue | ID: |
---|---|---|---|---|---|
T1 | 0-7 | ChemicalEntity | denotes | Calcium | http://purl.obolibrary.org/obo/CHEBI_22984 |
T2 | 39-46 | ChemicalEntity | denotes | glucose | D005947|http://purl.obolibrary.org/obo/CHEBI_4167|http://purl.obolibrary.org/obo/CHEBI_17234 |
T5 | 110-120 | ChemicalEntity | denotes | proteasome | D046988 |
T6 | 155-158 | ChemicalEntity | denotes | DCM | http://purl.obolibrary.org/obo/CHEBI_15767 |
T7 | 235-242 | ChemicalEntity | denotes | calcium | D002118|http://purl.obolibrary.org/obo/CHEBI_29320|http://purl.obolibrary.org/obo/CHEBI_22984 |
T10 | 333-340 | ChemicalEntity | denotes | calcium | D002118|http://purl.obolibrary.org/obo/CHEBI_29320|http://purl.obolibrary.org/obo/CHEBI_22984 |
T13 | 478-485 | ChemicalEntity | denotes | calcium | D002118|http://purl.obolibrary.org/obo/CHEBI_29320|http://purl.obolibrary.org/obo/CHEBI_22984 |
T16 | 550-553 | ChemicalEntity | denotes | DCM | http://purl.obolibrary.org/obo/CHEBI_15767 |
T17 | 720-727 | ChemicalEntity | denotes | glucose | D005947|http://purl.obolibrary.org/obo/CHEBI_4167|http://purl.obolibrary.org/obo/CHEBI_17234 |
T20 | 962-965 | ChemicalEntity | denotes | ATP | http://purl.obolibrary.org/obo/CHEBI_30616|http://purl.obolibrary.org/obo/CHEBI_15422 |
T22 | 1021-1024 | ChemicalEntity | denotes | ATP | http://purl.obolibrary.org/obo/CHEBI_30616|http://purl.obolibrary.org/obo/CHEBI_15422 |
T24 | 1400-1410 | ChemicalEntity | denotes | proteasome | D046988 |
T25 | 1546-1549 | ChemicalEntity | denotes | ATP | http://purl.obolibrary.org/obo/CHEBI_30616|http://purl.obolibrary.org/obo/CHEBI_15422 |
T27 | 1578-1581 | ChemicalEntity | denotes | ATP | http://purl.obolibrary.org/obo/CHEBI_30616|http://purl.obolibrary.org/obo/CHEBI_15422 |
T29 | 1756-1759 | ChemicalEntity | denotes | DCM | http://purl.obolibrary.org/obo/CHEBI_15767 |
LitCoin-NCBITaxon-2
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 207-215 | OrganismTaxon | denotes | patients |
T2 | 554-558 | OrganismTaxon | denotes | rats |
LitCoin-training-merged
Id | Subject | Object | Predicate | Lexical cue | #label | ID: |
---|---|---|---|---|---|---|
T29 | 1756-1759 | ChemicalEntity | denotes | DCM | http://purl.obolibrary.org/obo/CHEBI_15767 | |
T27 | 1578-1581 | ChemicalEntity | denotes | ATP | http://purl.obolibrary.org/obo/CHEBI_15422|http://purl.obolibrary.org/obo/CHEBI_30616 | |
T25 | 1546-1549 | ChemicalEntity | denotes | ATP | http://purl.obolibrary.org/obo/CHEBI_15422|http://purl.obolibrary.org/obo/CHEBI_30616 | |
T24 | 1400-1410 | ChemicalEntity | denotes | proteasome | D046988 | |
T22 | 1021-1024 | ChemicalEntity | denotes | ATP | http://purl.obolibrary.org/obo/CHEBI_15422|http://purl.obolibrary.org/obo/CHEBI_30616 | |
T20 | 962-965 | ChemicalEntity | denotes | ATP | http://purl.obolibrary.org/obo/CHEBI_15422|http://purl.obolibrary.org/obo/CHEBI_30616 | |
T17 | 720-727 | ChemicalEntity | denotes | glucose | http://purl.obolibrary.org/obo/CHEBI_17234|http://purl.obolibrary.org/obo/CHEBI_4167|D005947 | |
T16 | 550-553 | ChemicalEntity | denotes | DCM | http://purl.obolibrary.org/obo/CHEBI_15767 | |
T13 | 478-485 | ChemicalEntity | denotes | calcium | http://purl.obolibrary.org/obo/CHEBI_22984|http://purl.obolibrary.org/obo/CHEBI_29320|D002118 | |
T10 | 333-340 | ChemicalEntity | denotes | calcium | http://purl.obolibrary.org/obo/CHEBI_22984|http://purl.obolibrary.org/obo/CHEBI_29320|D002118 | |
T7 | 235-242 | ChemicalEntity | denotes | calcium | http://purl.obolibrary.org/obo/CHEBI_22984|http://purl.obolibrary.org/obo/CHEBI_29320|D002118 | |
T6 | 155-158 | ChemicalEntity | denotes | DCM | http://purl.obolibrary.org/obo/CHEBI_15767 | |
T5 | 110-120 | ChemicalEntity | denotes | proteasome | D046988 | |
T2 | 39-46 | ChemicalEntity | denotes | glucose | http://purl.obolibrary.org/obo/CHEBI_17234|http://purl.obolibrary.org/obo/CHEBI_4167|D005947 | |
T1 | 0-7 | ChemicalEntity | denotes | Calcium | http://purl.obolibrary.org/obo/CHEBI_22984 | |
T32 | 1697-1701 | GeneOrGeneProduct | denotes | CaSR | ||
T31 | 1606-1610 | GeneOrGeneProduct | denotes | CaSR | ||
T30 | 1400-1410 | GeneOrGeneProduct | denotes | proteasome | ||
T66927 | 1390-1399 | GeneOrGeneProduct | denotes | ubiquitin | ||
T28 | 1385-1389 | GeneOrGeneProduct | denotes | gp78 | ||
T96083 | 1350-1354 | GeneOrGeneProduct | denotes | CaSR | ||
T26 | 1190-1194 | GeneOrGeneProduct | denotes | gp78 | ||
T25719 | 1173-1177 | GeneOrGeneProduct | denotes | CaSR | ||
T8695 | 1157-1161 | GeneOrGeneProduct | denotes | Cx43 | ||
T23 | 1148-1152 | GeneOrGeneProduct | denotes | Mfn2 | ||
T54074 | 1142-1146 | GeneOrGeneProduct | denotes | Mfn1 | ||
T21 | 1102-1106 | GeneOrGeneProduct | denotes | Drp1 | ||
T35725 | 1096-1100 | GeneOrGeneProduct | denotes | Fis1 | ||
T19 | 1064-1094 | GeneOrGeneProduct | denotes | mitochondrial fission proteins | ||
T18 | 1058-1062 | GeneOrGeneProduct | denotes | gp78 | ||
T94452 | 931-941 | GeneOrGeneProduct | denotes | N-cadherin | ||
T3107 | 922-929 | GeneOrGeneProduct | denotes | catenin | ||
T15 | 914-918 | GeneOrGeneProduct | denotes | Cx43 | ||
T14 | 871-875 | GeneOrGeneProduct | denotes | Mfn2 | ||
T1351 | 865-869 | GeneOrGeneProduct | denotes | Mfn1 | ||
T12 | 834-863 | GeneOrGeneProduct | denotes | mitochondrial fusion proteins | ||
T11 | 828-832 | GeneOrGeneProduct | denotes | CaSR | ||
T42076 | 658-662 | GeneOrGeneProduct | denotes | CaSR | ||
T9 | 447-451 | GeneOrGeneProduct | denotes | CaSR | ||
T8 | 333-364 | GeneOrGeneProduct | denotes | calcium homeostasis, regulating | ||
T6815 | 272-298 | GeneOrGeneProduct | denotes | G protein-coupled receptor | ||
T56106 | 261-265 | GeneOrGeneProduct | denotes | CaSR | ||
T91326 | 235-259 | GeneOrGeneProduct | denotes | calcium sensing receptor | ||
T4 | 110-120 | GeneOrGeneProduct | denotes | proteasome | ||
T3 | 100-109 | GeneOrGeneProduct | denotes | ubiquitin | ||
T8022 | 95-99 | GeneOrGeneProduct | denotes | gp78 | ||
T76220 | 0-24 | GeneOrGeneProduct | denotes | Calcium sensing receptor | ||
T97009 | 1756-1759 | DiseaseOrPhenotypicFeature | denotes | DCM | D058065 | |
T30387 | 1647-1684 | DiseaseOrPhenotypicFeature | denotes | abnormal myocardial energy metabolism | DISEASE | |
T12484 | 1296-1333 | DiseaseOrPhenotypicFeature | denotes | myocardial energy metabolism disorder | DISEASE | |
T38540 | 666-703 | DiseaseOrPhenotypicFeature | denotes | myocardial energy metabolism disorder | DISEASE | |
T80324 | 550-553 | DiseaseOrPhenotypicFeature | denotes | DCM | D058065 | |
T28042 | 221-229 | DiseaseOrPhenotypicFeature | denotes | diabetes | DISEASE | |
T80732 | 155-158 | DiseaseOrPhenotypicFeature | denotes | DCM | D058065 | |
T64370 | 130-153 | DiseaseOrPhenotypicFeature | denotes | Diabetic cardiomyopathy | D058065 | |
T35104 | 62-81 | DiseaseOrPhenotypicFeature | denotes | metabolism disorder | DISEASE | |
T78306 | 554-558 | OrganismTaxon | denotes | rats | ||
T74485 | 207-215 | OrganismTaxon | denotes | patients |