> top > docs > PubMed:28512644 > annotations

PubMed:28512644 JSONTXT

Annnotations TAB JSON ListView MergeView

LitCoin-entities-OrganismTaxon-PD

Id Subject Object Predicate Lexical cue db_id
T1 190-203 OrganismTaxon denotes streptococcus NCBItxid:1301

LitCoin-sentences

Id Subject Object Predicate Lexical cue
T1 0-110 Sentence denotes Analysis of Serum Cytokines and Single-Nucleotide Polymorphisms of SOD1, SOD2, and CAT in Erysipelas Patients.
T2 111-220 Sentence denotes Increased free radical production had been documented in group A (β-hemolytic) streptococcus infection cases.
T3 221-491 Sentence denotes Comparing 71 erysipelas patients to 55 age-matched healthy individuals, we sought for CAT, SOD1, and SOD2 single polymorphism mutation (SNPs) interactions with erysipelas' predisposition and serum cytokine levels in the acute and recovery phases of erysipelas infection.
T4 492-633 Sentence denotes Whereas female patients had a higher predisposition to erysipelas, male patients were prone to having a facial localization of the infection.
T5 634-736 Sentence denotes The presence of SOD1 G7958, SOD2 T2734, and CAT C262 alleles was linked to erysipelas' predisposition.
T6 737-860 Sentence denotes T and C alleles of SOD2 T2734C individually were linked to patients with bullous and erythematous erysipelas, respectively.
T7 861-1004 Sentence denotes G and A alleles of SOD1 G7958A individually were associated with lower limbs and higher body part localizations of the infection, respectively.
T8 1005-1260 Sentence denotes Serum levels of IL-1β, CCL11, IL-2Rα, CXCL9, TRAIL, PDGF-BB, and CCL4 were associated with symptoms accompanying the infection, while IL-6, IL-9, IL-10, IL-13, IL-15, IL-17, G-CSF, and VEGF were associated with predisposition and recurrence of erysipelas.
T9 1261-1433 Sentence denotes While variations of IL-1β, IL-7, IL-8, IL-17, CCL5, and HGF were associated with the SOD2 T2734C SNP, variations of PDFG-BB and CCL2 were associated with the CAT C262T SNP.

LitCoin-entities

Id Subject Object Predicate Lexical cue db_id
12943 67-71 GeneOrGeneProduct denotes SOD1 NCBIGene:6647
12944 73-77 GeneOrGeneProduct denotes SOD2 NCBIGene:6648
12945 83-86 GeneOrGeneProduct denotes CAT NCBIGene:847
12946 90-100 DiseaseOrPhenotypicFeature denotes Erysipelas MESH:D004886
12947 101-109 OrganismTaxon denotes Patients NCBITaxon:9606
12948 190-213 DiseaseOrPhenotypicFeature denotes streptococcus infection MESH:D013290
12949 234-244 DiseaseOrPhenotypicFeature denotes erysipelas MESH:D004886
12950 245-253 OrganismTaxon denotes patients NCBITaxon:9606
12951 307-310 GeneOrGeneProduct denotes CAT NCBIGene:847
12952 312-316 GeneOrGeneProduct denotes SOD1 NCBIGene:6647
12953 322-326 GeneOrGeneProduct denotes SOD2 NCBIGene:6648
12954 381-391 DiseaseOrPhenotypicFeature denotes erysipelas MESH:D004886
12955 470-490 DiseaseOrPhenotypicFeature denotes erysipelas infection MESH:D004886
12956 507-515 OrganismTaxon denotes patients NCBITaxon:9606
12957 547-557 DiseaseOrPhenotypicFeature denotes erysipelas MESH:D004886
12958 564-572 OrganismTaxon denotes patients NCBITaxon:9606
12959 623-632 DiseaseOrPhenotypicFeature denotes infection MESH:D007239
12960 650-654 GeneOrGeneProduct denotes SOD1 NCBIGene:6647
12961 655-660 SequenceVariant denotes G7958 c|Aelle|G|7958
12962 662-666 GeneOrGeneProduct denotes SOD2 NCBIGene:6648
12963 667-672 SequenceVariant denotes T2734 c|Aelle|T|2734
12964 678-681 GeneOrGeneProduct denotes CAT NCBIGene:847
12965 682-686 SequenceVariant denotes C262 c|Aelle|C|262
12966 709-719 DiseaseOrPhenotypicFeature denotes erysipelas MESH:D004886
12967 756-760 GeneOrGeneProduct denotes SOD2 NCBIGene:6648
12968 761-767 SequenceVariant denotes T2734C c|SYB|T2734|C
12969 796-804 OrganismTaxon denotes patients NCBITaxon:9606
12970 822-845 DiseaseOrPhenotypicFeature denotes erythematous erysipelas MESH:D004886
12971 880-884 GeneOrGeneProduct denotes SOD1 NCBIGene:6647
12972 885-891 SequenceVariant denotes G7958A DBSNP:rs4998557
12973 980-989 DiseaseOrPhenotypicFeature denotes infection MESH:D007239
12974 1021-1026 GeneOrGeneProduct denotes IL-1β NCBIGene:3553
12975 1028-1033 GeneOrGeneProduct denotes CCL11 NCBIGene:6356
12976 1035-1041 GeneOrGeneProduct denotes IL-2Rα NCBIGene:3559
12977 1043-1048 GeneOrGeneProduct denotes CXCL9 NCBIGene:4283
12978 1050-1055 GeneOrGeneProduct denotes TRAIL NCBIGene:8743
12979 1057-1064 GeneOrGeneProduct denotes PDGF-BB NCBIGene:5155
12980 1070-1074 GeneOrGeneProduct denotes CCL4 NCBIGene:6351
12981 1122-1131 DiseaseOrPhenotypicFeature denotes infection MESH:D007239
12982 1139-1143 GeneOrGeneProduct denotes IL-6 NCBIGene:3569
12983 1145-1149 GeneOrGeneProduct denotes IL-9 NCBIGene:3578
12984 1151-1156 GeneOrGeneProduct denotes IL-10 NCBIGene:3586
12985 1158-1163 GeneOrGeneProduct denotes IL-13 NCBIGene:3596
12986 1165-1170 GeneOrGeneProduct denotes IL-15 NCBIGene:3600
12987 1172-1177 GeneOrGeneProduct denotes IL-17 NCBIGene:3605
12988 1179-1184 GeneOrGeneProduct denotes G-CSF NCBIGene:1440
12989 1190-1194 GeneOrGeneProduct denotes VEGF NCBIGene:7422
12990 1249-1259 DiseaseOrPhenotypicFeature denotes erysipelas MESH:D004886
12991 1281-1286 GeneOrGeneProduct denotes IL-1β NCBIGene:3553
12992 1288-1292 GeneOrGeneProduct denotes IL-7 NCBIGene:3574
12993 1294-1298 GeneOrGeneProduct denotes IL-8 NCBIGene:3576
12994 1300-1305 GeneOrGeneProduct denotes IL-17 NCBIGene:3605
12995 1307-1311 GeneOrGeneProduct denotes CCL5 NCBIGene:6352
12996 1317-1320 GeneOrGeneProduct denotes HGF NCBIGene:3082
12997 1346-1350 GeneOrGeneProduct denotes SOD2 NCBIGene:6648
12998 1351-1357 SequenceVariant denotes T2734C c|SYB|T2734|C
12999 1377-1384 GeneOrGeneProduct denotes PDFG-BB NCBIGene:5155
13000 1389-1393 GeneOrGeneProduct denotes CCL2 NCBIGene:6347
13001 1419-1422 GeneOrGeneProduct denotes CAT NCBIGene:847
13002 1423-1428 SequenceVariant denotes C262T c|SUB|C|262|T

LitCoin_Mondo

Id Subject Object Predicate Lexical cue mondo_id
T1 90-100 DiseaseOrPhenotypicFeature denotes Erysipelas 0001266
T2 234-244 DiseaseOrPhenotypicFeature denotes erysipelas 0001266
T3 381-391 DiseaseOrPhenotypicFeature denotes erysipelas 0001266
T4 470-480 DiseaseOrPhenotypicFeature denotes erysipelas 0001266
T5 547-557 DiseaseOrPhenotypicFeature denotes erysipelas 0001266
T6 709-719 DiseaseOrPhenotypicFeature denotes erysipelas 0001266
T7 835-845 DiseaseOrPhenotypicFeature denotes erysipelas 0001266
T8 1249-1259 DiseaseOrPhenotypicFeature denotes erysipelas 0001266

LitCoin-SeqVar

Id Subject Object Predicate Lexical cue
T1 761-767 SequenceVariant denotes T2734C
T2 885-891 SequenceVariant denotes G7958A
T3 1351-1357 SequenceVariant denotes T2734C
T4 1423-1428 SequenceVariant denotes C262T

LitCoin-GeneOrGeneProduct-v0

Id Subject Object Predicate Lexical cue
T1 67-71 GeneOrGeneProduct denotes SOD1
T2 73-77 GeneOrGeneProduct denotes SOD2
T3 83-86 GeneOrGeneProduct denotes CAT
T4 134-144 GeneOrGeneProduct denotes production
T5 214-219 GeneOrGeneProduct denotes cases
T6 307-310 GeneOrGeneProduct denotes CAT
T7 312-316 GeneOrGeneProduct denotes SOD1
T8 322-326 GeneOrGeneProduct denotes SOD2
T9 347-355 GeneOrGeneProduct denotes mutation
T10 516-521 GeneOrGeneProduct denotes had a
T11 559-563 GeneOrGeneProduct denotes male
T12 650-654 GeneOrGeneProduct denotes SOD1
T13 662-666 GeneOrGeneProduct denotes SOD2
T14 678-681 GeneOrGeneProduct denotes CAT
T15 699-705 GeneOrGeneProduct denotes linked
T16 756-760 GeneOrGeneProduct denotes SOD2
T17 786-792 GeneOrGeneProduct denotes linked
T18 880-884 GeneOrGeneProduct denotes SOD1
T19 932-937 GeneOrGeneProduct denotes limbs
T20 954-958 GeneOrGeneProduct denotes part
T21 1021-1025 GeneOrGeneProduct denotes IL-1
T22 1028-1033 GeneOrGeneProduct denotes CCL11
T23 1035-1040 GeneOrGeneProduct denotes IL-2R
T24 1043-1048 GeneOrGeneProduct denotes CXCL9
T25 1050-1055 GeneOrGeneProduct denotes TRAIL
T26 1057-1061 GeneOrGeneProduct denotes PDGF
T27 1070-1074 GeneOrGeneProduct denotes CCL4
T28 1139-1143 GeneOrGeneProduct denotes IL-6
T29 1145-1149 GeneOrGeneProduct denotes IL-9
T30 1151-1156 GeneOrGeneProduct denotes IL-10
T31 1158-1163 GeneOrGeneProduct denotes IL-13
T32 1165-1170 GeneOrGeneProduct denotes IL-15
T33 1172-1177 GeneOrGeneProduct denotes IL-17
T34 1179-1184 GeneOrGeneProduct denotes G-CSF
T35 1190-1194 GeneOrGeneProduct denotes VEGF
T36 1281-1285 GeneOrGeneProduct denotes IL-1
T37 1288-1292 GeneOrGeneProduct denotes IL-7
T38 1294-1298 GeneOrGeneProduct denotes IL-8
T39 1300-1305 GeneOrGeneProduct denotes IL-17
T40 1307-1311 GeneOrGeneProduct denotes CCL5
T41 1346-1350 GeneOrGeneProduct denotes SOD2
T42 1389-1393 GeneOrGeneProduct denotes CCL2
T43 1419-1422 GeneOrGeneProduct denotes CAT

LitCoin-GeneOrGeneProduct-v2

Id Subject Object Predicate Lexical cue
T1 67-71 GeneOrGeneProduct denotes SOD1
T2 73-77 GeneOrGeneProduct denotes SOD2
T3 312-316 GeneOrGeneProduct denotes SOD1
T4 322-326 GeneOrGeneProduct denotes SOD2
T5 650-654 GeneOrGeneProduct denotes SOD1
T6 662-666 GeneOrGeneProduct denotes SOD2
T7 756-760 GeneOrGeneProduct denotes SOD2
T8 880-884 GeneOrGeneProduct denotes SOD1
T9 1021-1025 GeneOrGeneProduct denotes IL-1
T10 1028-1033 GeneOrGeneProduct denotes CCL11
T11 1035-1040 GeneOrGeneProduct denotes IL-2R
T12 1043-1048 GeneOrGeneProduct denotes CXCL9
T13 1050-1055 GeneOrGeneProduct denotes TRAIL
T14 1057-1061 GeneOrGeneProduct denotes PDGF
T15 1070-1074 GeneOrGeneProduct denotes CCL4
T16 1139-1143 GeneOrGeneProduct denotes IL-6
T17 1145-1149 GeneOrGeneProduct denotes IL-9
T18 1151-1156 GeneOrGeneProduct denotes IL-10
T19 1158-1163 GeneOrGeneProduct denotes IL-13
T20 1165-1170 GeneOrGeneProduct denotes IL-15
T21 1172-1177 GeneOrGeneProduct denotes IL-17
T22 1179-1184 GeneOrGeneProduct denotes G-CSF
T23 1190-1194 GeneOrGeneProduct denotes VEGF
T24 1281-1285 GeneOrGeneProduct denotes IL-1
T25 1288-1292 GeneOrGeneProduct denotes IL-7
T26 1294-1298 GeneOrGeneProduct denotes IL-8
T27 1300-1305 GeneOrGeneProduct denotes IL-17
T28 1307-1311 GeneOrGeneProduct denotes CCL5
T29 1346-1350 GeneOrGeneProduct denotes SOD2
T30 1389-1393 GeneOrGeneProduct denotes CCL2

LitCoin-Disease-MeSH

Id Subject Object Predicate Lexical cue originalLabel
T1 90-100 DiseaseOrPhenotypicFeature denotes Erysipelas D004886
T2 204-213 DiseaseOrPhenotypicFeature denotes infection D007239
T3 234-244 DiseaseOrPhenotypicFeature denotes erysipelas D004886
T4 381-391 DiseaseOrPhenotypicFeature denotes erysipelas D004886
T5 470-480 DiseaseOrPhenotypicFeature denotes erysipelas D004886
T6 481-490 DiseaseOrPhenotypicFeature denotes infection D007239
T7 547-557 DiseaseOrPhenotypicFeature denotes erysipelas D004886
T8 623-632 DiseaseOrPhenotypicFeature denotes infection D007239
T9 709-719 DiseaseOrPhenotypicFeature denotes erysipelas D004886
T10 835-845 DiseaseOrPhenotypicFeature denotes erysipelas D004886
T11 980-989 DiseaseOrPhenotypicFeature denotes infection D007239
T12 1122-1131 DiseaseOrPhenotypicFeature denotes infection D007239
T13 1235-1245 DiseaseOrPhenotypicFeature denotes recurrence D012008
T14 1249-1259 DiseaseOrPhenotypicFeature denotes erysipelas D004886

LitCoin-GeneOrGeneProduct-v3

Id Subject Object Predicate Lexical cue
T1 67-71 GeneOrGeneProduct denotes SOD1
T2 73-77 GeneOrGeneProduct denotes SOD2
T3 312-316 GeneOrGeneProduct denotes SOD1
T4 322-326 GeneOrGeneProduct denotes SOD2
T5 650-654 GeneOrGeneProduct denotes SOD1
T6 662-666 GeneOrGeneProduct denotes SOD2
T7 756-760 GeneOrGeneProduct denotes SOD2
T8 880-884 GeneOrGeneProduct denotes SOD1
T9 1021-1025 GeneOrGeneProduct denotes IL-1
T10 1028-1033 GeneOrGeneProduct denotes CCL11
T11 1035-1040 GeneOrGeneProduct denotes IL-2R
T12 1043-1048 GeneOrGeneProduct denotes CXCL9
T13 1050-1055 GeneOrGeneProduct denotes TRAIL
T14 1057-1061 GeneOrGeneProduct denotes PDGF
T15 1070-1074 GeneOrGeneProduct denotes CCL4
T16 1139-1143 GeneOrGeneProduct denotes IL-6
T17 1145-1149 GeneOrGeneProduct denotes IL-9
T18 1151-1156 GeneOrGeneProduct denotes IL-10
T19 1158-1163 GeneOrGeneProduct denotes IL-13
T20 1165-1170 GeneOrGeneProduct denotes IL-15
T21 1172-1177 GeneOrGeneProduct denotes IL-17
T22 1179-1184 GeneOrGeneProduct denotes G-CSF
T23 1190-1194 GeneOrGeneProduct denotes VEGF
T24 1281-1285 GeneOrGeneProduct denotes IL-1
T25 1288-1292 GeneOrGeneProduct denotes IL-7
T26 1294-1298 GeneOrGeneProduct denotes IL-8
T27 1300-1305 GeneOrGeneProduct denotes IL-17
T28 1307-1311 GeneOrGeneProduct denotes CCL5
T29 1346-1350 GeneOrGeneProduct denotes SOD2
T30 1389-1393 GeneOrGeneProduct denotes CCL2

LitCoin_Mondo_095

Id Subject Object Predicate Lexical cue mondo_id
T1 90-100 DiseaseOrPhenotypicFeature denotes Erysipelas 0001266
T2 204-213 DiseaseOrPhenotypicFeature denotes infection 0005550
T3 234-244 DiseaseOrPhenotypicFeature denotes erysipelas 0001266
T4 381-391 DiseaseOrPhenotypicFeature denotes erysipelas 0001266
T5 470-480 DiseaseOrPhenotypicFeature denotes erysipelas 0001266
T6 481-490 DiseaseOrPhenotypicFeature denotes infection 0005550
T7 547-557 DiseaseOrPhenotypicFeature denotes erysipelas 0001266
T8 623-632 DiseaseOrPhenotypicFeature denotes infection 0005550
T9 709-719 DiseaseOrPhenotypicFeature denotes erysipelas 0001266
T10 835-845 DiseaseOrPhenotypicFeature denotes erysipelas 0001266
T11 980-989 DiseaseOrPhenotypicFeature denotes infection 0005550
T12 1122-1131 DiseaseOrPhenotypicFeature denotes infection 0005550
T13 1249-1259 DiseaseOrPhenotypicFeature denotes erysipelas 0001266

LitCoin-MeSH-Disease-2

Id Subject Object Predicate Lexical cue ID:
T1 90-100 DiseaseOrPhenotypicFeature denotes Erysipelas D004886
T2 204-213 DiseaseOrPhenotypicFeature denotes infection D007239
T3 234-244 DiseaseOrPhenotypicFeature denotes erysipelas D004886
T4 381-391 DiseaseOrPhenotypicFeature denotes erysipelas D004886
T5 470-480 DiseaseOrPhenotypicFeature denotes erysipelas D004886
T6 481-490 DiseaseOrPhenotypicFeature denotes infection D007239
T7 547-557 DiseaseOrPhenotypicFeature denotes erysipelas D004886
T8 623-632 DiseaseOrPhenotypicFeature denotes infection D007239
T9 709-719 DiseaseOrPhenotypicFeature denotes erysipelas D004886
T10 835-845 DiseaseOrPhenotypicFeature denotes erysipelas D004886
T11 980-989 DiseaseOrPhenotypicFeature denotes infection D007239
T12 1122-1131 DiseaseOrPhenotypicFeature denotes infection D007239
T13 1235-1245 DiseaseOrPhenotypicFeature denotes recurrence D012008
T14 1249-1259 DiseaseOrPhenotypicFeature denotes erysipelas D004886

LitCoin-MONDO_bioort2019

Id Subject Object Predicate Lexical cue #label
T1 90-100 DiseaseOrPhenotypicFeature denotes Erysipelas D004886
T2 234-244 DiseaseOrPhenotypicFeature denotes erysipelas D004886
T3 381-391 DiseaseOrPhenotypicFeature denotes erysipelas D004886
T4 470-480 DiseaseOrPhenotypicFeature denotes erysipelas D004886
T5 547-557 DiseaseOrPhenotypicFeature denotes erysipelas D004886
T6 709-719 DiseaseOrPhenotypicFeature denotes erysipelas D004886
T7 835-845 DiseaseOrPhenotypicFeature denotes erysipelas D004886
T8 1249-1259 DiseaseOrPhenotypicFeature denotes erysipelas D004886

LitCoin-NCBITaxon-2

Id Subject Object Predicate Lexical cue
T1 83-86 OrganismTaxon denotes CAT
T2 190-203 OrganismTaxon denotes streptococcus
T3 245-253 OrganismTaxon denotes patients
T4 307-310 OrganismTaxon denotes CAT
T5 507-515 OrganismTaxon denotes patients
T6 564-572 OrganismTaxon denotes patients
T7 678-681 OrganismTaxon denotes CAT
T8 796-804 OrganismTaxon denotes patients
T9 1419-1422 OrganismTaxon denotes CAT

LitCoin-Chemical-MeSH-CHEBI

Id Subject Object Predicate Lexical cue ID:
T1 121-133 ChemicalEntity denotes free radical D005609|http://purl.obolibrary.org/obo/CHEBI_26519
T3 1043-1048 ChemicalEntity denotes CXCL9 http://purl.obolibrary.org/obo/CHEBI_138154

LitCoin-training-merged

Id Subject Object Predicate Lexical cue #label ID:
T3 1043-1048 ChemicalEntity denotes CXCL9 http://purl.obolibrary.org/obo/CHEBI_138154
T1 121-133 ChemicalEntity denotes free radical http://purl.obolibrary.org/obo/CHEBI_26519|D005609
T30 1389-1393 GeneOrGeneProduct denotes CCL2
T29 1346-1350 GeneOrGeneProduct denotes SOD2
T28 1307-1311 GeneOrGeneProduct denotes CCL5
T27 1300-1305 GeneOrGeneProduct denotes IL-17
T26 1294-1298 GeneOrGeneProduct denotes IL-8
T25 1288-1292 GeneOrGeneProduct denotes IL-7
T24 1281-1285 GeneOrGeneProduct denotes IL-1
T23 1190-1194 GeneOrGeneProduct denotes VEGF
T22 1179-1184 GeneOrGeneProduct denotes G-CSF
T21 1172-1177 GeneOrGeneProduct denotes IL-17
T20 1165-1170 GeneOrGeneProduct denotes IL-15
T19 1158-1163 GeneOrGeneProduct denotes IL-13
T18 1151-1156 GeneOrGeneProduct denotes IL-10
T17 1145-1149 GeneOrGeneProduct denotes IL-9
T16 1139-1143 GeneOrGeneProduct denotes IL-6
T15 1070-1074 GeneOrGeneProduct denotes CCL4
T14 1057-1061 GeneOrGeneProduct denotes PDGF
T13 1050-1055 GeneOrGeneProduct denotes TRAIL
T12 1043-1048 GeneOrGeneProduct denotes CXCL9
T11 1035-1040 GeneOrGeneProduct denotes IL-2R
T10 1028-1033 GeneOrGeneProduct denotes CCL11
T9 1021-1025 GeneOrGeneProduct denotes IL-1
T8 880-884 GeneOrGeneProduct denotes SOD1
T7 756-760 GeneOrGeneProduct denotes SOD2
T6 662-666 GeneOrGeneProduct denotes SOD2
T5 650-654 GeneOrGeneProduct denotes SOD1
T4 322-326 GeneOrGeneProduct denotes SOD2
T14774 312-316 GeneOrGeneProduct denotes SOD1
T2 73-77 GeneOrGeneProduct denotes SOD2
T57184 67-71 GeneOrGeneProduct denotes SOD1
T94783 1249-1259 DiseaseOrPhenotypicFeature denotes erysipelas D004886
T64571 835-845 DiseaseOrPhenotypicFeature denotes erysipelas D004886
T1804 709-719 DiseaseOrPhenotypicFeature denotes erysipelas D004886
T39231 547-557 DiseaseOrPhenotypicFeature denotes erysipelas D004886
T83265 470-480 DiseaseOrPhenotypicFeature denotes erysipelas D004886
T72878 381-391 DiseaseOrPhenotypicFeature denotes erysipelas D004886
T73416 234-244 DiseaseOrPhenotypicFeature denotes erysipelas D004886
T85636 90-100 DiseaseOrPhenotypicFeature denotes Erysipelas D004886
T45408 1419-1422 OrganismTaxon denotes CAT
T345 796-804 OrganismTaxon denotes patients
T10420 678-681 OrganismTaxon denotes CAT
T41460 564-572 OrganismTaxon denotes patients
T29240 507-515 OrganismTaxon denotes patients
T71961 307-310 OrganismTaxon denotes CAT
T60226 245-253 OrganismTaxon denotes patients
T54566 190-203 OrganismTaxon denotes streptococcus
T72634 83-86 OrganismTaxon denotes CAT
T90512 1423-1428 SequenceVariant denotes C262T
T32567 1351-1357 SequenceVariant denotes T2734C
T50270 885-891 SequenceVariant denotes G7958A
T21512 761-767 SequenceVariant denotes T2734C