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kaiyin_test

Id Subject Object Predicate Lexical cue
T1 0-4 Var denotes Loss
T2 42-47 Gene denotes rad51
T3 48-53 Reg denotes leads
T4 57-85 Disease denotes Fanconi anemia-like symptoms
T5 246-260 Disease denotes Fanconi anemia
T6 579-584 Gene denotes rad51
T7 585-601 NegReg denotes loss-of-function
T8 602-609 Var denotes mutants
T9 636-638 Disease denotes FA
R1 T1 T3 CauseOf Loss,leads
R2 T4 T3 ThemeOf Fanconi anemia-like symptoms,leads
R3 T2 T1 ThemeOf rad51,Loss
R4 T8 T7 CauseOf mutants,loss-of-function
R5 T9 T7 ThemeOf FA,loss-of-function
R6 T6 T8 ThemeOf rad51,mutants

name_no

Id Subject Object Predicate Lexical cue
T1 0-4 Var denotes Loss
T2 42-47 Gene denotes rad51
T3 48-53 Reg denotes leads
T4 57-85 Disease denotes Fanconi anemia-like symptoms
T5 246-260 Disease denotes Fanconi anemia
T6 579-584 Gene denotes rad51
T7 585-601 NegReg denotes loss-of-function
T8 602-609 Var denotes mutants
T9 636-638 Disease denotes FA
R1 T1 T3 CauseOf Loss,leads
R2 T4 T3 ThemeOf Fanconi anemia-like symptoms,leads
R3 T2 T1 ThemeOf rad51,Loss
R4 T8 T7 CauseOf mutants,loss-of-function
R5 T9 T7 ThemeOf FA,loss-of-function
R6 T6 T8 ThemeOf rad51,mutants

Inflammaging

Id Subject Object Predicate Lexical cue
T1 0-99 Sentence denotes Loss of the homologous recombination gene rad51 leads to Fanconi anemia-like symptoms in zebrafish.
T2 100-208 Sentence denotes RAD51 is an indispensable homologous recombination protein, necessary for strand invasion and crossing over.
T3 209-349 Sentence denotes It has recently been designated as a Fanconi anemia (FA) gene, following the discovery of two patients carrying dominant-negative mutations.
T4 350-499 Sentence denotes FA is a hereditary DNA-repair disorder characterized by various congenital abnormalities, progressive bone marrow failure, and cancer predisposition.
T5 500-568 Sentence denotes In this report, we describe a viable vertebrate model of RAD51 loss.
T6 569-734 Sentence denotes Zebrafish rad51 loss-of-function mutants developed key features of FA, including hypocellular kidney marrow, sensitivity to cross-linking agents, and decreased size.
T7 735-887 Sentence denotes We show that some of these symptoms stem from both decreased proliferation and increased apoptosis of embryonic hematopoietic stem and progenitor cells.
T8 888-1008 Sentence denotes Comutation of p53 was able to rescue the hematopoietic defects seen in the single mutants, but led to tumor development.
T9 1009-1176 Sentence denotes We further demonstrate that prolonged inflammatory stress can exacerbate the hematological impairment, leading to an additional decrease in kidney marrow cell numbers.
T10 1177-1395 Sentence denotes These findings strengthen the assignment of RAD51 as a Fanconi gene and provide more evidence for the notion that aberrant p53 signaling during embryogenesis leads to the hematological defects seen later in life in FA.
T11 1396-1559 Sentence denotes Further research on this zebrafish FA model will lead to a deeper understanding of the molecular basis of bone marrow failure in FA and the cellular role of RAD51.
T1 0-99 Sentence denotes Loss of the homologous recombination gene rad51 leads to Fanconi anemia-like symptoms in zebrafish.
T2 100-208 Sentence denotes RAD51 is an indispensable homologous recombination protein, necessary for strand invasion and crossing over.
T3 209-349 Sentence denotes It has recently been designated as a Fanconi anemia (FA) gene, following the discovery of two patients carrying dominant-negative mutations.
T4 350-499 Sentence denotes FA is a hereditary DNA-repair disorder characterized by various congenital abnormalities, progressive bone marrow failure, and cancer predisposition.
T5 500-568 Sentence denotes In this report, we describe a viable vertebrate model of RAD51 loss.
T6 569-734 Sentence denotes Zebrafish rad51 loss-of-function mutants developed key features of FA, including hypocellular kidney marrow, sensitivity to cross-linking agents, and decreased size.
T7 735-887 Sentence denotes We show that some of these symptoms stem from both decreased proliferation and increased apoptosis of embryonic hematopoietic stem and progenitor cells.
T8 888-1008 Sentence denotes Comutation of p53 was able to rescue the hematopoietic defects seen in the single mutants, but led to tumor development.
T9 1009-1176 Sentence denotes We further demonstrate that prolonged inflammatory stress can exacerbate the hematological impairment, leading to an additional decrease in kidney marrow cell numbers.
T10 1177-1395 Sentence denotes These findings strengthen the assignment of RAD51 as a Fanconi gene and provide more evidence for the notion that aberrant p53 signaling during embryogenesis leads to the hematological defects seen later in life in FA.
T11 1396-1559 Sentence denotes Further research on this zebrafish FA model will lead to a deeper understanding of the molecular basis of bone marrow failure in FA and the cellular role of RAD51.