PubMed:28498326
Annnotations
GoldHamster
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T3 | 59-78 | UBERON:0001066 | denotes | Intervertebral Disc |
| T4 | 59-91 | D055959 | denotes | Intervertebral Disc Degeneration |
| T5 | 59-91 | D055959 | denotes | Intervertebral Disc Degeneration |
| T10 | 156-175 | UBERON:0001066 | denotes | Intervertebral Disc |
| T8 | 156-175 | C535531 | denotes | Intervertebral Disc |
| T9 | 156-175 | C535531 | denotes | Intervertebral Disc |
| T11 | 176-188 | GO:0031099 | denotes | Regeneration |
| T12 | 291-308 | D055959 | denotes | disc degeneration |
| T13 | 291-308 | D055959 | denotes | disc degeneration |
| T14 | 313-325 | GO:0031099 | denotes | regeneration |
| T15 | 335-340 | D012757 | denotes | ovine |
| T16 | 335-340 | D012757 | denotes | ovine |
| T17 | 378-395 | D055959 | denotes | disc degeneration |
| T18 | 378-395 | D055959 | denotes | disc degeneration |
| T19 | 397-411 | CHEBI:87647 | denotes | Toluidine blue |
| T20 | 397-411 | D014048 | denotes | Toluidine blue |
| T21 | 397-411 | D014048 | denotes | Toluidine blue |
| T22 | 416-428 | CHEBI:51686 | denotes | Haematoxylin |
| T23 | 416-428 | CHEBI:5601 | denotes | Haematoxylin |
| T24 | 416-428 | CHEBI:51684 | denotes | Haematoxylin |
| T25 | 433-438 | 1310593 | denotes | Eosin |
| T26 | 433-438 | D004801 | denotes | Eosin |
| T27 | 433-438 | D004801 | denotes | Eosin |
| T28 | 442-445 | D000249 | denotes | amp |
| T29 | 442-445 | D000249 | denotes | amp |
| T30 | 442-445 | CHEBI:456215 | denotes | amp |
| T31 | 442-445 | CHEBI:16027 | denotes | amp |
| T32 | 442-445 | CHEBI:28971 | denotes | amp |
| T33 | 502-509 | GO:0031674 | denotes | i) disc |
| T34 | 544-556 | CHEBI:37396 | denotes | proteoglycan |
| T36 | 544-556 | D011509 | denotes | proteoglycan |
| T37 | 544-556 | D011509 | denotes | proteoglycan |
| T35 | 544-556 | GO:0005203 | denotes | proteoglycan |
| T38 | 600-612 | UBERON:0001981 | denotes | blood vessel |
| T43 | 692-702 | GO:0036074 | denotes | metaplasia |
| T40 | 692-702 | UBERON:4000142 | denotes | metaplasia |
| T41 | 692-702 | D008679 | denotes | metaplasia |
| T42 | 692-702 | D008679 | denotes | metaplasia |
| T45 | 799-820 | CL:0000134 | denotes | mesenchymal stem cell |
| T47 | 822-825 | PR:000010664 | denotes | MSC |
| T48 | 822-825 | PR:O60682 | denotes | MSC |
| T49 | 822-825 | PR:O88940 | denotes | MSC |
| T50 | 822-825 | CL:0000134 | denotes | MSC |
| T51 | 933-938 | SO:0001685 | denotes | score |
| T52 | 983-988 | PR:O00910 | denotes | STATA |
| T53 | 1005-1017 | CHEBI:37396 | denotes | proteoglycan |
| T55 | 1005-1017 | D011509 | denotes | proteoglycan |
| T56 | 1005-1017 | D011509 | denotes | proteoglycan |
| T54 | 1005-1017 | GO:0005203 | denotes | proteoglycan |
| T58 | 1065-1068 | A6QNQ6 | denotes | rim |
| T59 | 1065-1068 | Q99708 | denotes | rim |
| T60 | 1065-1068 | Q22366 | denotes | rim |
| T61 | 1065-1068 | B1WC58 | denotes | rim |
| T62 | 1065-1068 | PR:000013780 | denotes | rim |
| T63 | 1065-1068 | Q80YR6 | denotes | rim |
| T57 | 1065-1068 | CVCL_KR50 | denotes | rim |
| T64 | 1065-1068 | UBERON:0003147 | denotes | rim |
| T65 | 1130-1136 | UBERON:0001364 | denotes | radial |
| T66 | 1145-1150 | UBERON:0001827 | denotes | tears |
| T67 | 1174-1187 | UBERON:0004537 | denotes | blood vessels |
| T69 | 1346-1350 | PR:000023297 | denotes | MSCs |
| T70 | 1346-1350 | PR:P0C0S1 | denotes | MSCs |
| T68 | 1346-1350 | GO:0043854 | denotes | MSCs |
| T71 | 1404-1413 | MOP:0000569 | denotes | reduction |
| T72 | 1454-1459 | SO:0001685 | denotes | score |
| T76 | 1543-1550 | CHEBI:78059 | denotes | carrier |
| T75 | 1543-1550 | GO:0005215 | denotes | carrier |
PubMed_ArguminSci
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 190-396 | DRI_Background | denotes | The purpose of this study was to develop a quantitative histopathological scoring scheme to evaluate disc degeneration and regeneration using an ovine annular lesion model of experimental disc degeneration. |
| T2 | 397-703 | DRI_Approach | denotes | Toluidine blue and Haematoxylin and Eosin (H&E) staining were used to evaluate cellular morphology: (i) disc structure/lesion morphology; (ii) proteoglycan depletion; (iii) cellular morphology; (iv) blood vessel in-growth; (v) cell influx into lesion; and (vi) cystic degeneration/chondroid metaplasia. |
| T3 | 704-837 | DRI_Background | denotes | Three study groups were examined: 5 × 5 mm lesion; 6 × 20 mm lesion; and 6 × 20 mm lesion plus mesenchymal stem cell (MSC) treatment. |
| T4 | 838-998 | DRI_Background | denotes | Lumbar intervertebral discs (IVDs) were scored under categories (i-vi) to provide a cumulative score, which underwent statistical analysis using STATA software. |
| T5 | 999-1258 | DRI_Background | denotes | Focal proteoglycan depletion was associated with 5 × 5 mm annular rim lesions, bifurcations, annular delamellation, concentric and radial annular tears and an early influx of blood vessels and cells around remodeling lesions but the inner lesion did not heal. |
| T6 | 1259-1345 | DRI_Approach | denotes | Similar features in 6 × 20 mm lesions occurred over a 3-6-month post operative period. |
| T7 | 1346-1566 | DRI_Approach | denotes | MSCs induced a strong recovery in discal pathology with a reduction in cumulative histopathology degeneracy score from 15.2 to 2.7 (p = 0.001) over a three-month recovery period but no recovery in carrier injected discs. |
Goldhamster2_Cellosaurus
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T19 | 1311-1312 | CVCL_6479|Finite_cell_line|Mus musculus | denotes | a |
| T1 | 0-1 | CVCL_6479|Finite_cell_line|Mus musculus | denotes | A |
| T2 | 231-232 | CVCL_6479|Finite_cell_line|Mus musculus | denotes | a |
| T3 | 332-334 | CVCL_8754|Cancer_cell_line|Homo sapiens | denotes | an |
| T4 | 332-334 | CVCL_H241|Cancer_cell_line|Homo sapiens | denotes | an |
| T5 | 759-761 | CVCL_J923|Hybridoma|Mus musculus | denotes | 20 |
| T6 | 781-783 | CVCL_J923|Hybridoma|Mus musculus | denotes | 20 |
| T7 | 920-921 | CVCL_6479|Finite_cell_line|Mus musculus | denotes | a |
| T8 | 1065-1068 | CVCL_KR50|Hybridoma|Mus musculus | denotes | rim |
| T9 | 1155-1157 | CVCL_8754|Cancer_cell_line|Homo sapiens | denotes | an |
| T10 | 1155-1157 | CVCL_H241|Cancer_cell_line|Homo sapiens | denotes | an |
| T11 | 1283-1285 | CVCL_J923|Hybridoma|Mus musculus | denotes | 20 |
| T12 | 1311-1314 | CVCL_1061|Cancer_cell_line|Homo sapiens | denotes | a 3 |
| T13 | 1311-1314 | CVCL_1Q37|Spontaneously_immortalized_cell_line|Cricetulus griseus | denotes | a 3 |
| T14 | 1311-1314 | CVCL_5A61|Spontaneously_immortalized_cell_line|Cricetulus griseus | denotes | a 3 |
| T15 | 1311-1314 | CVCL_G649|Hybridoma|Mus musculus | denotes | a 3 |
| T16 | 1311-1314 | CVCL_JH29|Cancer_cell_line|Homo sapiens | denotes | a 3 |
| T17 | 1311-1314 | CVCL_LN35|Cancer_cell_line|Homo sapiens | denotes | a 3 |
| T18 | 1311-1314 | CVCL_ZU43|Transformed_cell_line|Homo sapiens | denotes | a 3 |
| T20 | 1359-1360 | CVCL_6479|Finite_cell_line|Mus musculus | denotes | a |
| T21 | 1402-1403 | CVCL_6479|Finite_cell_line|Mus musculus | denotes | a |
| T22 | 1494-1495 | CVCL_6479|Finite_cell_line|Mus musculus | denotes | a |