PubMed:28490634 / 1660-1925 JSONTXT

{"project":"sentences","denotations":[{"id":"T8","span":{"begin":0,"end":265},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Both matriptase and prostasin are significantly down-regulated in colonic tissues from human subjects with active ulcerative colitis or Crohn's disease, implicating the loss of this barrier-protective protease pathway in the pathogenesis of irritable bowel disease."}

{"project":"Glycosmos6-MAT","denotations":[{"id":"T2","span":{"begin":66,"end":73},"obj":"http://purl.obolibrary.org/obo/MAT_0000526"}],"text":"Both matriptase and prostasin are significantly down-regulated in colonic tissues from human subjects with active ulcerative colitis or Crohn's disease, implicating the loss of this barrier-protective protease pathway in the pathogenesis of irritable bowel disease."}

{"project":"Inflammaging","denotations":[{"id":"T8","span":{"begin":0,"end":265},"obj":"Sentence"},{"id":"T8","span":{"begin":0,"end":265},"obj":"Sentence"}],"text":"Both matriptase and prostasin are significantly down-regulated in colonic tissues from human subjects with active ulcerative colitis or Crohn's disease, implicating the loss of this barrier-protective protease pathway in the pathogenesis of irritable bowel disease."}

{"project":"mondo_disease","denotations":[{"id":"T13","span":{"begin":114,"end":132},"obj":"Disease"},{"id":"T15","span":{"begin":136,"end":151},"obj":"Disease"}],"attributes":[{"id":"A13","pred":"mondo_id","subj":"T13","obj":"http://purl.obolibrary.org/obo/MONDO_0005101"},{"id":"A14","pred":"mondo_id","subj":"T13","obj":"http://purl.obolibrary.org/obo/MONDO_0009960"},{"id":"A15","pred":"mondo_id","subj":"T15","obj":"http://purl.obolibrary.org/obo/MONDO_0005011"}],"text":"Both matriptase and prostasin are significantly down-regulated in colonic tissues from human subjects with active ulcerative colitis or Crohn's disease, implicating the loss of this barrier-protective protease pathway in the pathogenesis of irritable bowel disease."}

{"project":"HP-phenotype","denotations":[{"id":"T10","span":{"begin":114,"end":132},"obj":"Phenotype"},{"id":"T11","span":{"begin":136,"end":151},"obj":"Phenotype"},{"id":"T12","span":{"begin":241,"end":250},"obj":"Phenotype"}],"attributes":[{"id":"A10","pred":"hp_id","subj":"T10","obj":"HP:0100279"},{"id":"A11","pred":"hp_id","subj":"T11","obj":"HP:0100280"},{"id":"A12","pred":"hp_id","subj":"T12","obj":"HP:0000737"}],"namespaces":[{"prefix":"HP","uri":"http://purl.obolibrary.org/obo/HP_"}],"text":"Both matriptase and prostasin are significantly down-regulated in colonic tissues from human subjects with active ulcerative colitis or Crohn's disease, implicating the loss of this barrier-protective protease pathway in the pathogenesis of irritable bowel disease."}

{"project":"NCBITAXON","denotations":[{"id":"T3","span":{"begin":87,"end":92},"obj":"OrganismTaxon"}],"attributes":[{"id":"A3","pred":"db_id","subj":"T3","obj":"9606"}],"text":"Both matriptase and prostasin are significantly down-regulated in colonic tissues from human subjects with active ulcerative colitis or Crohn's disease, implicating the loss of this barrier-protective protease pathway in the pathogenesis of irritable bowel disease."}

{"project":"Anatomy-UBERON","denotations":[{"id":"T5","span":{"begin":251,"end":256},"obj":"Body_part"}],"attributes":[{"id":"A5","pred":"uberon_id","subj":"T5","obj":"http://purl.obolibrary.org/obo/UBERON_0000160"}],"text":"Both matriptase and prostasin are significantly down-regulated in colonic tissues from human subjects with active ulcerative colitis or Crohn's disease, implicating the loss of this barrier-protective protease pathway in the pathogenesis of irritable bowel disease."}

{"project":"Anatomy-MAT","denotations":[{"id":"T2","span":{"begin":66,"end":73},"obj":"Body_part"}],"attributes":[{"id":"A2","pred":"mat_id","subj":"T2","obj":"http://purl.obolibrary.org/obo/MAT_0000526"}],"text":"Both matriptase and prostasin are significantly down-regulated in colonic tissues from human subjects with active ulcerative colitis or Crohn's disease, implicating the loss of this barrier-protective protease pathway in the pathogenesis of irritable bowel disease."}