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PubMed:28486813 JSONTXT

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GoldHamster

Id Subject Object Predicate Lexical cue
T1 72-78 UBERON:0000982 denotes Joints
T3 241-245 PR:000023297 denotes MSCs
T4 241-245 PR:P0C0S1 denotes MSCs
T2 241-245 GO:0043854 denotes MSCs
T8 406-428 UBERON:0009984 denotes medial femoral condyle
T12 441-445 PR:000023297 denotes MSCs
T13 441-445 PR:P0C0S1 denotes MSCs
T11 441-445 GO:0043854 denotes MSCs
T16 465-475 UBERON:0001485 denotes knee joint
T19 498-505 D011817 denotes rabbits
T20 498-505 9986 denotes rabbits
T21 602-605 PR:000010664 denotes MSC
T22 602-605 PR:O60682 denotes MSC
T23 602-605 PR:O88940 denotes MSC
T24 602-605 CL:0000134 denotes MSC
T27 653-657 PR:000023297 denotes MSCs
T28 653-657 PR:P0C0S1 denotes MSCs
T26 653-657 GO:0043854 denotes MSCs
T29 668-674 UBERON:0000479 denotes tissue
T34 775-779 PR:000023297 denotes MSCs
T35 775-779 PR:P0C0S1 denotes MSCs
T33 775-779 GO:0043854 denotes MSCs
T36 823-829 UBERON:0000479 denotes tissue
T40 902-905 PR:000010664 denotes MSC
T41 902-905 PR:O60682 denotes MSC
T42 902-905 PR:O88940 denotes MSC
T43 902-905 CL:0000134 denotes MSC
T44 971-977 UBERON:0000479 denotes tissue
T48 1084-1087 PR:000010664 denotes MSC
T49 1084-1087 PR:O60682 denotes MSC
T50 1084-1087 PR:O88940 denotes MSC
T51 1084-1087 CL:0000134 denotes MSC
T52 1133-1136 PR:000010664 denotes MSC
T53 1133-1136 PR:O60682 denotes MSC
T54 1133-1136 PR:O88940 denotes MSC
T55 1133-1136 CL:0000134 denotes MSC
T59 1195-1201 UBERON:0000479 denotes tissue
T60 1214-1219 UBERON:0000119 denotes layer
T61 1214-1219 UBERON:0022303 denotes layer
T65 1248-1265 UBERON:0010996 denotes hyaline cartilage
T66 1248-1265 UBERON:0001994 denotes hyaline cartilage
T69 1256-1275 GO:0051216 denotes cartilage formation
T71 1305-1311 UBERON:0000479 denotes tissue
T72 1353-1358 UBERON:0000119 denotes layer
T73 1353-1358 UBERON:0022303 denotes layer
T74 1366-1372 CVCL_E031 denotes center
T75 1388-1404 UBERON:0035878 denotes Subchondral bone
T81 1451-1454 PR:000010664 denotes MSC
T82 1451-1454 PR:O60682 denotes MSC
T83 1451-1454 PR:O88940 denotes MSC
T84 1451-1454 CL:0000134 denotes MSC
T85 1503-1507 UBERON:0001474 denotes bone
T86 1503-1507 UBERON:0002481 denotes bone
T90 1573-1577 PR:000023297 denotes MSCs
T91 1573-1577 PR:P0C0S1 denotes MSCs
T89 1573-1577 GO:0043854 denotes MSCs
T92 1606-1622 UBERON:0035878 denotes subchondral bone

PubMed_Structured_Abstracts

Id Subject Object Predicate Lexical cue
T1 118-300 OBJECTIVE denotes The aim of this study was to evaluate an intraarticular injection of different doses of autologous mesenchymal stem cells (MSCs) for improving repair of midterm osteochondral defect.
T2 309-780 DESIGN denotes At 4 weeks postoperative marrow stimulation model bilaterally (3 mm diameter; 4 mm depth) in the medial femoral condyle, autologous MSCs were injected into knee joint. Twenty-four Japanese rabbits aged 6 months were divided randomly into 4 groups ( n = 6 per group): the control group and and MSC groups including 0.125, 1.25, and 6.25 million MSCs. Repaired tissue was assessed macroscopically and histologically at 4 and 12 weeks after intraarticular injection of MSCs.
T3 790-1508 RESULTS denotes At 12 weeks, there was no repair tissue in the control group. The gross appearance of the 1.25 and 6.25 million MSC groups revealed complete repair of the defect with white to pink tissue at 12 weeks. An osteochondral repair was histologically significantly better in the 1.25 and 6.25 million MSC groups than in the control and 0.125 million MSC groups at 4 and 12 weeks, due to presence of hyaline-like tissue in the deep layer at 4 weeks, and at 12 weeks hyaline cartilage formation at the periphery and fibrous tissue containing some chondrocytes in the deep layer of the center of the defect. Subchondral bone was restructured in the 1.25 and 6.25 million MSC groups, although it did not resemble the normal bone.
T4 1521-1673 CONCLUSION denotes An intraarticular injection of 1.25 or 6.25 million MSCs could promote the repair of subchondral bone, even in the case of midterm osteochondral defect.

Goldhamster2_Cellosaurus

Id Subject Object Predicate Lexical cue
T1 156-158 CVCL_8754|Cancer_cell_line|Homo sapiens denotes an
T2 156-158 CVCL_H241|Cancer_cell_line|Homo sapiens denotes an
T3 309-313 CVCL_Y660|Cancer_cell_line|Rattus norvegicus denotes At 4
T4 558-563 CVCL_D461|Transformed_cell_line|Mus musculus denotes n = 6
T5 723-727 CVCL_Y660|Cancer_cell_line|Rattus norvegicus denotes at 4
T6 991-993 CVCL_8754|Cancer_cell_line|Homo sapiens denotes An
T7 991-993 CVCL_H241|Cancer_cell_line|Homo sapiens denotes An
T8 1144-1148 CVCL_Y660|Cancer_cell_line|Rattus norvegicus denotes at 4
T9 1220-1224 CVCL_Y660|Cancer_cell_line|Rattus norvegicus denotes at 4
T10 1366-1372 CVCL_E031|Induced_pluripotent_stem_cell|Homo sapiens denotes center
T11 1400-1408 CVCL_D953|Induced_pluripotent_stem_cell|Homo sapiens denotes bone was
T12 1503-1507 CVCL_D953|Induced_pluripotent_stem_cell|Homo sapiens denotes bone
T13 1521-1523 CVCL_8754|Cancer_cell_line|Homo sapiens denotes An
T14 1521-1523 CVCL_H241|Cancer_cell_line|Homo sapiens denotes An
T15 1618-1622 CVCL_D953|Induced_pluripotent_stem_cell|Homo sapiens denotes bone