| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T1 |
160-391 |
DRI_Challenge |
denotes |
Background Diffusion-weighted imaging (DWI) and fluid-attenuated inversion recovery (FLAIR) mismatch was suggested to identify stroke patients with unknown time of symptom onset likely to be within the time window for thrombolysis. |
| T2 |
392-513 |
DRI_Challenge |
denotes |
Aims We aimed to study clinical characteristics associated with DWI-FLAIR mismatch in patients with unknown onset stroke. |
| T3 |
514-778 |
DRI_Outcome |
denotes |
Methods We analyzed baseline MRI and clinical data from patients with acute ischemic stroke proven by DWI from WAKE-UP, an investigator-initiated, randomized, placebo-controlled trial of MRI-based thrombolysis in stroke patients with unknown time of symptom onset. |
| T4 |
779-871 |
DRI_Background |
denotes |
Clinical characteristics were compared between patients with and without DWI-FLAIR mismatch. |
| T5 |
953-1221 |
DRI_Approach |
denotes |
A shorter delay between last seen well and symptom recognition (p = 0.0063), a shorter delay between symptom recognition and arrival at hospital (p = 0.0025), and history of atrial fibrillation (p = 0.19) were predictors of DWI-FLAIR mismatch in multivariate analysis. |
| T6 |
1222-1279 |
DRI_Approach |
denotes |
All other characteristics were comparable between groups. |
| T7 |
1280-1444 |
DRI_Challenge |
denotes |
Conclusions There are only minor differences in measured clinical characteristics between unknown symptom onset stroke patients with and without DWI-FLAIR mismatch. |
| T8 |
1445-1607 |
DRI_Outcome |
denotes |
DWI-FLAIR mismatch as an indicator of stroke onset within 4.5 h shows no relevant association with commonly collected clinical characteristics of stroke patients. |
