PubMed:28404752
Annnotations
PubMed_ArguminSci
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 73-250 | DRI_Background | denotes | lly organized macromolecular complexes are essential for cell and tissue function, but the mechanisms that organize micron-scale structures within cells are not well understood. |
| T2 | 251-396 | DRI_Outcome | denotes | Microtubule-based structures such as mitotic spindles scale with cell size, but less is known about the scaling of actin structures within cells. |
| T3 | 397-407 | REPLACED | denotes | Actin-rich |
| T4 | 417-566 | DRI_Outcome | denotes | precursors cover the ventral surface of the Drosophila embryo and larva and provide templates for cuticular structures involved in larval locomotion. |
| T5 | 567-745 | DRI_Approach | denotes | Using quantitative imaging and statistical modeling, we demonstrate that denticle number and spacing scale with cell length over a wide range of cell sizes in embryos and larvae. |
| T6 | 746-911 | DRI_Approach | denotes | Denticle number and spacing are reduced under space-limited conditions, and both features robustly scale over a 10-fold increase in cell length during larval growth. |
| T7 | 912-1191 | DRI_Outcome | denotes | We show that the relationship between cell length and denticle spacing can be recapitulated by specific mathematical equations in embryos and larvae and that accurate denticle spacing requires an intact microtubule network and the microtubule minus end-binding protein, Patronin. |
| T8 | 1192-1348 | DRI_Challenge | denotes | These results identify a novel mechanism of micro-tubule-dependent actin scaling that maintains precise patterns of actin organization during tissue growth. |
Goldhamster2_Cellosaurus
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 296-304 | CVCL_E018|Induced_pluripotent_stem_cell|Homo sapiens | denotes | spindles |
| T2 | 620-622 | CVCL_5M23|Cancer_cell_line|Mesocricetus auratus | denotes | we |
| T3 | 696-697 | CVCL_6479|Finite_cell_line|Mus musculus | denotes | a |
| T4 | 856-860 | CVCL_0130|Spontaneously_immortalized_cell_line|Rattus norvegicus | denotes | a 10 |
| T5 | 856-857 | CVCL_6479|Finite_cell_line|Mus musculus | denotes | a |
| T6 | 912-914 | CVCL_5M23|Cancer_cell_line|Mesocricetus auratus | denotes | We |
| T7 | 1105-1107 | CVCL_8754|Cancer_cell_line|Homo sapiens | denotes | an |
| T8 | 1105-1107 | CVCL_H241|Cancer_cell_line|Homo sapiens | denotes | an |
| T9 | 1215-1216 | CVCL_6479|Finite_cell_line|Mus musculus | denotes | a |
GoldHamster
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 55-65 | 2294143 | denotes | Drosophila |
| T2 | 55-65 | 504603 | denotes | Drosophila |
| T3 | 55-65 | 2294139 | denotes | Drosophila |
| T4 | 55-65 | 2294145 | denotes | Drosophila |
| T5 | 55-65 | 2294141 | denotes | Drosophila |
| T6 | 55-65 | 2294142 | denotes | Drosophila |
| T7 | 55-65 | 2294144 | denotes | Drosophila |
| T8 | 55-65 | 2294140 | denotes | Drosophila |
| T9 | 55-65 | D004330 | denotes | Drosophila |
| T10 | 55-65 | 2080301 | denotes | Drosophila |
| T11 | 87-111 | D046911 | denotes | macromolecular complexes |
| T12 | 139-145 | UBERON:0000479 | denotes | tissue |
| T13 | 196-201 | UBERON:0002542 | denotes | scale |
| T14 | 251-262 | GO:0005874 | denotes | Microtubule |
| T15 | 305-310 | UBERON:0002542 | denotes | scale |
| T16 | 366-371 | P53491 | denotes | actin |
| T17 | 366-371 | P45520 | denotes | actin |
| T18 | 366-371 | O00937 | denotes | actin |
| T19 | 366-371 | Q05214 | denotes | actin |
| T20 | 366-371 | P13363 | denotes | actin |
| T21 | 366-371 | Q39596 | denotes | actin |
| T22 | 366-371 | P30161 | denotes | actin |
| T23 | 366-371 | P53476 | denotes | actin |
| T24 | 366-371 | P51775 | denotes | actin |
| T25 | 366-371 | P60011 | denotes | actin |
| T26 | 366-371 | Q9P4D1 | denotes | actin |
| T27 | 366-371 | P50138 | denotes | actin |
| T28 | 366-371 | O65314 | denotes | actin |
| T29 | 366-371 | P26183 | denotes | actin |
| T30 | 366-371 | Q75D00 | denotes | actin |
| T31 | 366-371 | P53502 | denotes | actin |
| T32 | 366-371 | P11426 | denotes | actin |
| T33 | 366-371 | P80709 | denotes | actin |
| T34 | 366-371 | Q8X119 | denotes | actin |
| T35 | 366-371 | Q6TCF2 | denotes | actin |
| T36 | 366-371 | Q99023 | denotes | actin |
| T37 | 366-371 | A5DQP9 | denotes | actin |
| T38 | 366-371 | P60009 | denotes | actin |
| T39 | 366-371 | O65315 | denotes | actin |
| T40 | 366-371 | P26182 | denotes | actin |
| T41 | 366-371 | Q9UVF3 | denotes | actin |
| T42 | 366-371 | Q2U7A3 | denotes | actin |
| T43 | 366-371 | Q92192 | denotes | actin |
| T44 | 366-371 | Q9UVZ8 | denotes | actin |
| T45 | 366-371 | P53689 | denotes | actin |
| T46 | 366-371 | P68555 | denotes | actin |
| T47 | 366-371 | P53455 | denotes | actin |
| T48 | 366-371 | O13419 | denotes | actin |
| T49 | 366-371 | P60010 | denotes | actin |
| T50 | 366-371 | Q39758 | denotes | actin |
| T51 | 366-371 | P81085 | denotes | actin |
| T52 | 366-371 | P48465 | denotes | actin |
| T53 | 366-371 | P78711 | denotes | actin |
| T54 | 366-371 | P17128 | denotes | actin |
| T55 | 366-371 | P91754 | denotes | actin |
| T56 | 366-371 | Q24733 | denotes | actin |
| T57 | 366-371 | P14235 | denotes | actin |
| T58 | 366-371 | Q92193 | denotes | actin |
| T59 | 366-371 | Q11212 | denotes | actin |
| T60 | 366-371 | P45521 | denotes | actin |
| T61 | 366-371 | P53477 | denotes | actin |
| T62 | 366-371 | P53499 | denotes | actin |
| T63 | 366-371 | P24902 | denotes | actin |
| T64 | 366-371 | Q8SWN8 | denotes | actin |
| T65 | 366-371 | O17320 | denotes | actin |
| T66 | 366-371 | P10365 | denotes | actin |
| T68 | 366-371 | O16808 | denotes | actin |
| T69 | 366-371 | P53498 | denotes | actin |
| T70 | 366-371 | Q9UVX4 | denotes | actin |
| T71 | 366-371 | O81221 | denotes | actin |
| T72 | 366-371 | P20904 | denotes | actin |
| T73 | 366-371 | O65316 | denotes | actin |
| T74 | 366-371 | O74258 | denotes | actin |
| T75 | 366-371 | P53500 | denotes | actin |
| T76 | 366-371 | P10989 | denotes | actin |
| T77 | 366-371 | P90689 | denotes | actin |
| T67 | 366-371 | D000199 | denotes | actin |
| T78 | 397-402 | P53491 | denotes | Actin |
| T79 | 397-402 | P45520 | denotes | Actin |
| T80 | 397-402 | O00937 | denotes | Actin |
| T81 | 397-402 | Q05214 | denotes | Actin |
| T82 | 397-402 | P13363 | denotes | Actin |
| T83 | 397-402 | Q39596 | denotes | Actin |
| T84 | 397-402 | P30161 | denotes | Actin |
| T85 | 397-402 | P53476 | denotes | Actin |
| T86 | 397-402 | P51775 | denotes | Actin |
| T87 | 397-402 | P60011 | denotes | Actin |
| T88 | 397-402 | Q9P4D1 | denotes | Actin |
| T89 | 397-402 | P50138 | denotes | Actin |
| T90 | 397-402 | O65314 | denotes | Actin |
| T91 | 397-402 | P26183 | denotes | Actin |
| T92 | 397-402 | Q75D00 | denotes | Actin |
| T93 | 397-402 | P53502 | denotes | Actin |
| T94 | 397-402 | P11426 | denotes | Actin |
| T95 | 397-402 | P80709 | denotes | Actin |
| T96 | 397-402 | Q8X119 | denotes | Actin |
| T97 | 397-402 | Q6TCF2 | denotes | Actin |
| T98 | 397-402 | Q99023 | denotes | Actin |
| T99 | 397-402 | A5DQP9 | denotes | Actin |
| T100 | 397-402 | P60009 | denotes | Actin |
| T101 | 397-402 | O65315 | denotes | Actin |
| T102 | 397-402 | P26182 | denotes | Actin |
| T103 | 397-402 | Q9UVF3 | denotes | Actin |
| T104 | 397-402 | Q2U7A3 | denotes | Actin |
| T105 | 397-402 | Q92192 | denotes | Actin |
| T106 | 397-402 | Q9UVZ8 | denotes | Actin |
| T107 | 397-402 | P53689 | denotes | Actin |
| T108 | 397-402 | P68555 | denotes | Actin |
| T109 | 397-402 | P53455 | denotes | Actin |
| T110 | 397-402 | O13419 | denotes | Actin |
| T111 | 397-402 | P60010 | denotes | Actin |
| T112 | 397-402 | Q39758 | denotes | Actin |
| T113 | 397-402 | P81085 | denotes | Actin |
| T114 | 397-402 | P48465 | denotes | Actin |
| T115 | 397-402 | P78711 | denotes | Actin |
| T116 | 397-402 | P17128 | denotes | Actin |
| T117 | 397-402 | P91754 | denotes | Actin |
| T118 | 397-402 | Q24733 | denotes | Actin |
| T119 | 397-402 | P14235 | denotes | Actin |
| T120 | 397-402 | Q92193 | denotes | Actin |
| T121 | 397-402 | Q11212 | denotes | Actin |
| T122 | 397-402 | P45521 | denotes | Actin |
| T123 | 397-402 | P53477 | denotes | Actin |
| T124 | 397-402 | P53499 | denotes | Actin |
| T125 | 397-402 | P24902 | denotes | Actin |
| T126 | 397-402 | Q8SWN8 | denotes | Actin |
| T127 | 397-402 | O17320 | denotes | Actin |
| T128 | 397-402 | P10365 | denotes | Actin |
| T130 | 397-402 | O16808 | denotes | Actin |
| T131 | 397-402 | P53498 | denotes | Actin |
| T132 | 397-402 | Q9UVX4 | denotes | Actin |
| T133 | 397-402 | O81221 | denotes | Actin |
| T134 | 397-402 | P20904 | denotes | Actin |
| T135 | 397-402 | O65316 | denotes | Actin |
| T136 | 397-402 | O74258 | denotes | Actin |
| T137 | 397-402 | P53500 | denotes | Actin |
| T138 | 397-402 | P10989 | denotes | Actin |
| T139 | 397-402 | P90689 | denotes | Actin |
| T129 | 397-402 | D000199 | denotes | Actin |
| T140 | 408-416 | D003784 | denotes | denticle |
| T141 | 408-416 | D003784 | denotes | denticle |
| T142 | 461-471 | 2294143 | denotes | Drosophila |
| T143 | 461-471 | 504603 | denotes | Drosophila |
| T144 | 461-471 | 2294139 | denotes | Drosophila |
| T145 | 461-471 | 2294145 | denotes | Drosophila |
| T146 | 461-471 | 2294141 | denotes | Drosophila |
| T147 | 461-471 | 2294142 | denotes | Drosophila |
| T148 | 461-471 | 2294144 | denotes | Drosophila |
| T149 | 461-471 | 2294140 | denotes | Drosophila |
| T150 | 461-471 | D004330 | denotes | Drosophila |
| T151 | 461-471 | 2080301 | denotes | Drosophila |
| T152 | 472-478 | UBERON:0000922 | denotes | embryo |
| T155 | 483-488 | D007814 | denotes | larva |
| T153 | 483-488 | UBERON:0000069 | denotes | larva |
| T154 | 483-488 | UBERON:0002548 | denotes | larva |
| T156 | 483-488 | UBERON:0004728 | denotes | larva |
| T157 | 555-565 | GO:0040011 | denotes | locomotion |
| T158 | 640-648 | D003784 | denotes | denticle |
| T159 | 640-648 | D003784 | denotes | denticle |
| T160 | 668-673 | UBERON:0002542 | denotes | scale |
| T161 | 738-744 | D007814 | denotes | larvae |
| T162 | 746-754 | D003784 | denotes | Denticle |
| T163 | 746-754 | D003784 | denotes | Denticle |
| T164 | 845-850 | UBERON:0002542 | denotes | scale |
| T171 | 861-865 | PR:000022679 | denotes | fold |
| T172 | 861-865 | PR:Q2FZJ6 | denotes | fold |
| T173 | 861-865 | PR:A5I112 | denotes | fold |
| T174 | 861-865 | PR:P24186 | denotes | fold |
| T175 | 966-974 | D003784 | denotes | denticle |
| T176 | 966-974 | D003784 | denotes | denticle |
| T177 | 1054-1060 | D007814 | denotes | larvae |
| T178 | 1079-1087 | D003784 | denotes | denticle |
| T179 | 1079-1087 | D003784 | denotes | denticle |
| T180 | 1115-1126 | GO:0005874 | denotes | microtubule |
| T182 | 1143-1164 | GO:0036449 | denotes | microtubule minus end |
| T183 | 1143-1172 | GO:0051011 | denotes | microtubule minus end-binding |
| T184 | 1165-1172 | SO:0100018 | denotes | binding |
| T185 | 1165-1172 | SO:0001091 | denotes | binding |
| T187 | 1165-1180 | D002352 | denotes | binding protein |
| T192 | 1173-1180 | SO:0000104 | denotes | protein |
| T191 | 1173-1180 | PR:000000001 | denotes | protein |
| T188 | 1173-1180 | GO:0003675 | denotes | protein |
| T193 | 1182-1190 | A1ZAU8 | denotes | Patronin |
| T194 | 1182-1190 | PR:A1ZAU8 | denotes | Patronin |
| T195 | 1259-1264 | P53491 | denotes | actin |
| T196 | 1259-1264 | P45520 | denotes | actin |
| T197 | 1259-1264 | O00937 | denotes | actin |
| T198 | 1259-1264 | Q05214 | denotes | actin |
| T199 | 1259-1264 | P13363 | denotes | actin |
| T200 | 1259-1264 | Q39596 | denotes | actin |
| T201 | 1259-1264 | P30161 | denotes | actin |
| T202 | 1259-1264 | P53476 | denotes | actin |
| T203 | 1259-1264 | P51775 | denotes | actin |
| T204 | 1259-1264 | P60011 | denotes | actin |
| T205 | 1259-1264 | Q9P4D1 | denotes | actin |
| T206 | 1259-1264 | P50138 | denotes | actin |
| T207 | 1259-1264 | O65314 | denotes | actin |
| T208 | 1259-1264 | P26183 | denotes | actin |
| T209 | 1259-1264 | Q75D00 | denotes | actin |
| T210 | 1259-1264 | P53502 | denotes | actin |
| T211 | 1259-1264 | P11426 | denotes | actin |
| T212 | 1259-1264 | P80709 | denotes | actin |
| T213 | 1259-1264 | Q8X119 | denotes | actin |
| T214 | 1259-1264 | Q6TCF2 | denotes | actin |
| T215 | 1259-1264 | Q99023 | denotes | actin |
| T216 | 1259-1264 | A5DQP9 | denotes | actin |
| T217 | 1259-1264 | P60009 | denotes | actin |
| T218 | 1259-1264 | O65315 | denotes | actin |
| T219 | 1259-1264 | P26182 | denotes | actin |
| T220 | 1259-1264 | Q9UVF3 | denotes | actin |
| T221 | 1259-1264 | Q2U7A3 | denotes | actin |
| T222 | 1259-1264 | Q92192 | denotes | actin |
| T223 | 1259-1264 | Q9UVZ8 | denotes | actin |
| T224 | 1259-1264 | P53689 | denotes | actin |
| T225 | 1259-1264 | P68555 | denotes | actin |
| T226 | 1259-1264 | P53455 | denotes | actin |
| T227 | 1259-1264 | O13419 | denotes | actin |
| T228 | 1259-1264 | P60010 | denotes | actin |
| T229 | 1259-1264 | Q39758 | denotes | actin |
| T230 | 1259-1264 | P81085 | denotes | actin |
| T231 | 1259-1264 | P48465 | denotes | actin |
| T232 | 1259-1264 | P78711 | denotes | actin |
| T233 | 1259-1264 | P17128 | denotes | actin |
| T234 | 1259-1264 | P91754 | denotes | actin |
| T235 | 1259-1264 | Q24733 | denotes | actin |
| T236 | 1259-1264 | P14235 | denotes | actin |
| T237 | 1259-1264 | Q92193 | denotes | actin |
| T238 | 1259-1264 | Q11212 | denotes | actin |
| T239 | 1259-1264 | P45521 | denotes | actin |
| T240 | 1259-1264 | P53477 | denotes | actin |
| T241 | 1259-1264 | P53499 | denotes | actin |
| T242 | 1259-1264 | P24902 | denotes | actin |
| T243 | 1259-1264 | Q8SWN8 | denotes | actin |
| T244 | 1259-1264 | O17320 | denotes | actin |
| T245 | 1259-1264 | P10365 | denotes | actin |
| T247 | 1259-1264 | O16808 | denotes | actin |
| T248 | 1259-1264 | P53498 | denotes | actin |
| T249 | 1259-1264 | Q9UVX4 | denotes | actin |
| T250 | 1259-1264 | O81221 | denotes | actin |
| T251 | 1259-1264 | P20904 | denotes | actin |
| T252 | 1259-1264 | O65316 | denotes | actin |
| T253 | 1259-1264 | O74258 | denotes | actin |
| T254 | 1259-1264 | P53500 | denotes | actin |
| T255 | 1259-1264 | P10989 | denotes | actin |
| T256 | 1259-1264 | P90689 | denotes | actin |
| T246 | 1259-1264 | D000199 | denotes | actin |
| T257 | 1308-1313 | P53491 | denotes | actin |
| T258 | 1308-1313 | P45520 | denotes | actin |
| T259 | 1308-1313 | O00937 | denotes | actin |
| T260 | 1308-1313 | Q05214 | denotes | actin |
| T261 | 1308-1313 | P13363 | denotes | actin |
| T262 | 1308-1313 | Q39596 | denotes | actin |
| T263 | 1308-1313 | P30161 | denotes | actin |
| T264 | 1308-1313 | P53476 | denotes | actin |
| T265 | 1308-1313 | P51775 | denotes | actin |
| T266 | 1308-1313 | P60011 | denotes | actin |
| T267 | 1308-1313 | Q9P4D1 | denotes | actin |
| T268 | 1308-1313 | P50138 | denotes | actin |
| T269 | 1308-1313 | O65314 | denotes | actin |
| T270 | 1308-1313 | P26183 | denotes | actin |
| T271 | 1308-1313 | Q75D00 | denotes | actin |
| T272 | 1308-1313 | P53502 | denotes | actin |
| T273 | 1308-1313 | P11426 | denotes | actin |
| T274 | 1308-1313 | P80709 | denotes | actin |
| T275 | 1308-1313 | Q8X119 | denotes | actin |
| T276 | 1308-1313 | Q6TCF2 | denotes | actin |
| T277 | 1308-1313 | Q99023 | denotes | actin |
| T278 | 1308-1313 | A5DQP9 | denotes | actin |
| T279 | 1308-1313 | P60009 | denotes | actin |
| T280 | 1308-1313 | O65315 | denotes | actin |
| T281 | 1308-1313 | P26182 | denotes | actin |
| T282 | 1308-1313 | Q9UVF3 | denotes | actin |
| T283 | 1308-1313 | Q2U7A3 | denotes | actin |
| T284 | 1308-1313 | Q92192 | denotes | actin |
| T285 | 1308-1313 | Q9UVZ8 | denotes | actin |
| T286 | 1308-1313 | P53689 | denotes | actin |
| T287 | 1308-1313 | P68555 | denotes | actin |
| T288 | 1308-1313 | P53455 | denotes | actin |
| T289 | 1308-1313 | O13419 | denotes | actin |
| T290 | 1308-1313 | P60010 | denotes | actin |
| T291 | 1308-1313 | Q39758 | denotes | actin |
| T292 | 1308-1313 | P81085 | denotes | actin |
| T293 | 1308-1313 | P48465 | denotes | actin |
| T294 | 1308-1313 | P78711 | denotes | actin |
| T295 | 1308-1313 | P17128 | denotes | actin |
| T296 | 1308-1313 | P91754 | denotes | actin |
| T297 | 1308-1313 | Q24733 | denotes | actin |
| T298 | 1308-1313 | P14235 | denotes | actin |
| T299 | 1308-1313 | Q92193 | denotes | actin |
| T300 | 1308-1313 | Q11212 | denotes | actin |
| T301 | 1308-1313 | P45521 | denotes | actin |
| T302 | 1308-1313 | P53477 | denotes | actin |
| T303 | 1308-1313 | P53499 | denotes | actin |
| T304 | 1308-1313 | P24902 | denotes | actin |
| T305 | 1308-1313 | Q8SWN8 | denotes | actin |
| T306 | 1308-1313 | O17320 | denotes | actin |
| T307 | 1308-1313 | P10365 | denotes | actin |
| T309 | 1308-1313 | O16808 | denotes | actin |
| T310 | 1308-1313 | P53498 | denotes | actin |
| T311 | 1308-1313 | Q9UVX4 | denotes | actin |
| T312 | 1308-1313 | O81221 | denotes | actin |
| T313 | 1308-1313 | P20904 | denotes | actin |
| T314 | 1308-1313 | O65316 | denotes | actin |
| T315 | 1308-1313 | O74258 | denotes | actin |
| T316 | 1308-1313 | P53500 | denotes | actin |
| T317 | 1308-1313 | P10989 | denotes | actin |
| T318 | 1308-1313 | P90689 | denotes | actin |
| T308 | 1308-1313 | D000199 | denotes | actin |
| T319 | 1334-1340 | UBERON:0000479 | denotes | tissue |